Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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Operators and Enhancers/Silencers

Wikipedia has two images, of a eukaryotic gene and of a prokaryotic gene. They show the difference that the prokaryotic gene also has an operator while the eukaryotic gene does not. Both also have ...
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Why do humans have 46 chromosomes? [duplicate]

Humans have approximately 25000 genes. Why are these genes on 46 chromosomes? Why not 40 or 50?
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How could one calculate the gene flow between two populations?

Imagine there are two populations X and Y, and for each population you have the genotypes of each individual in that population (e.g. Aa, AA, aa, etc.), but for multiple loci (e.g. AABb). How could ...
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Difference Between Gene Delivery and Gene Therapy

What is the specific difference between gene delivery and gene therapy? As far as I understand, gene delivery is the first step of gene therapy, but where does gene delivery end and gene therapy ...
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Known ways to modify the genetic structure of the 13 loci used in CODIS

After reading the answer to Does our DNA change during our lives?, I was wondering if and how it would be possible to change the structure of the 13 loci that are used in the CODIS database, in such a ...
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Are fishes evolving?

As far as I know, Fishing has been one of the important occupation since early ages, and infinite number of fishes have already been captured. As the time passes, they must've developed some sort of ...
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Can an argument be made that humans are 90% bacterial?

On the blog, All about Scientist in Microword: Microbiology, I read the post We are 90% bacteria, actually, which says that humans are 90% bacterial cells. If this is the case, then why don't we ...
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84 views

How many genes does D. melanogaster have?

Obviously there is no 100% exact number, but I came across this on flybase, the gold standard for annotation. I am confused now. "Genes located to the genome", is that what I am looking for? If so, ...
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“Signal Advance”: Unsure of meaning or contextual use

I am reading through Recombinant DNA; Genes and Genomes - A Short Course - Third Edition by James D. Watson, et. al. and I came across this paragraph in the discussion about discrete factors of ...
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33 views

Is it possible to have raw ngs data to practice

I'm looking for raw human ngs data to practice in bioinformatics. Better if it is from different machines (illumina, roche, pacsbio, etc). Panels, exomes and genomes. Anyone knows something?
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Microbiome Data

How is it possible to access microbiome data like that found here? I'd like to perform analyses on similar type of data, but cannot find OTU data like that at the Human Biome Project. Thanks for any ...
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Why do we assume that the first humans were dark-skinned?

According to the article Dark skin and blue eyes: How Europeans once looked: It is widely accepted that Man's oldest common forefather was dark skinned, and that people became more pale as they ...
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Colorblindness in females and random X chromosome inactivation

From Annenberg Learner: Because the X is inactivated randomly in cells, one cell could have the maternal X inactivated, while the adjacent cell could have the paternal X inactivated. This causes ...
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321 views

What does it mean to have a Y-DNA Haplogroup “R-M512”? [closed]

I did a DNA test to learn about my origins, but the results are highly technical. I see I have a Y-DNA Haplogroup R-M512 and a mutation (zero marker in DYS448). I Googled these terms and came across ...
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4k views

How does plant grafting work?

Plant grafting is a process whereby a piece of one plant is inserted into another and results in a change of the original plant. For example, grafting a piece of a lemon tree into a bitter orange tree ...
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HIV and open reading frames

In Wilk et al. 2001 I saw that HIV has 3 open reading frames. In the Watts et al. 2009, I noticed they mentioned HIV has 9 open reading frames. I don't understand this very well. e.g. ...
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31 views

What is the Genetic Cause of Homosexuality? [duplicate]

So, I'm just wondering about this because I read the following in my Biology textbook about fruit fly genes: "Normal male and female flies express distinct forms of the fru gene. When females are ...
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8k views

Is diabetes mellitus a sex-linked disease?

There are two types of diabetes mellitus. a. Type 1 diabetes mellitus b. Type 2 diabetes melliuts Is either of them a sex linked disease? Can either one be inherited? My book says, "this disease is ...
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When performing mutagenesis for an assay, how do you decide on the sample size of individuals to be mutated such that all genes are covered?

If I want to study, say, gustatory response of salmons to a bile acid, I need to mutagenize a sample of salmon males. However, given that there are many genes involved in this response, what is ...
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614 views

Can genes change as we age?

Let's say you're a 23 year old man who impregnates a woman. Will your genes be the same if you were to impregnate another woman at age 35? Will your genes in those 12 years have ...
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Please explain this disrepancy about ageing

We read that ageing is related to cell death when we run out of telomeres at the end of our DNA molecules. Humans live roughly for 70 years - the traditional three-score years and ten. This compares ...
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86 views

What does it mean to clone a gene?

When I look up information related to the identification of disease genes, texts will often refer to the gene being "first cloned." What does "clone" mean in this context? Is it simply a synonym for ...
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How was the cama's life expectancy computed?

A cama is a hybrid between a male dromedary camel and a female llama. The first cama was born on January 14, 1998, yet on the Wikipedia page it is said that a cama's life span is 30–40 years. How was ...
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163 views

Why are hybrid offspring mostly sterile? [closed]

Hybrid infertility is a common trait in cross-species offspring. Most are sterile, as they do not produce viable gametes. Examples of this can include Ligers and Mules. Could modern advancement in ...
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Sexual selection and genotypes [closed]

I have question about genetics and sexual selection. This is re-worded from a problem that was posed to help me and others understand what is going on here. Say you have a fictional species on an ...
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28 views

Why are we supposed as unable to change our intrinsic behaviour? [closed]

People say that habit can be changed but not the intrinsic behavior of an individual. One can control it for a certain period but eternal control or refrain is not possible. Is that true? If yes why? ...
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Math backbone in biology/genetic

Are there any good books, that shows some advanced models in genetics particularly? The problem is i don't see any good math model in genetics interactions exept combinatorics. I'd like to know what ...
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Amputation of part of the cytoplasm of the amoeba? [closed]

We ampute a part of the cytoplasm of the amoeba many times and we observe that amoeba is not divided This experience allows to deduce the cause of the division of amoeba Do that have relation with ...
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How often does bacterial transformation happen?

I have been reading: M. Dröge, A. Pühler, W. Selbitschka, "Horizontal gene transfer among bacteria in terrestrial and aquatic habitats as assessed by microcosm and field studies", Biol. Fertil. ...
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161 views

Are non-coding RNAs introns?

I am slightly confused as to what part of the genome codes for non-coding RNAs. Is it the introns? This would make sense to me as to why they are not transcribed as the introns are not transcribed. Or ...
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genetic complementation problem

I've attached the picture of the problem. SO, based on the information I managed to assemble two large cistrons. (if the combination of two mutants yield (-) mutations are on the same chromosome) ...
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What is the instructional language of DNA?

DNA carries most of the genetic instructions used in the development, functioning and reproduction of all known living organisms and many viruses (Wikipedia). Is it already know how ATCG's ...
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Difference between micro RNA and short-interfering RNA and CRISPR Cas 9 system?

I read this article https://www.quantamagazine.org/20150206-crispr-dna-editor-bacteria/ and am slightly puzzled as to why the CRISPR/Cas 9 system is seen as being so revolutionary. It seems like the ...
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recombination frequency problem

Three loci C, D and E are located on the same chromosome in this order. We found that the frequency of recombinants between C and D is 10% and that between D and E it is 20%. Assuming that ...
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Why can't this be 1st meiotic division non-disjunction as well?

The child has gotten 2 "sick" chromosomes from his dad and 1 healthy from his mom, leaving it with trisomy 13. I can see how this can happen in the second meiotic division of the father but I can ...
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Gel Electrophoresis

we add Etbr within the agarose gel but we do not add Etbr directly in native PAGE ?when we make agarose gel, we add Etbr before its solidification but we do not add Etbr when the native PAGE gel is in ...
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49 views

Coefficient of Inbreeding - implementation issue

The formula for the coefficient of inbreeding is as follows... I have a family tree going back 9 generations. Say I find a common ancestor X in the 4th generation on the mothers side and in the 5th ...
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Why does size decrease across the sequence of human chromosomes?

The following graph shows a decrease in the amount of base pairs per chromosome across the sequential set of human chromosomes: Is this because chromosomes were originally numbered by their size on ...
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Fur genetics - what are the causes of fur colour decision?

This Australian Shepherd puppy's father is a black-tri; mother is a blue merle. What would cause this dog to have so much white color? Are there any general explanations as to why this might ...
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332 views

Can bacteria release free DNA into their environment?

Natural transformation AKA natural competence involves the uptake of DNA into a competent bacterium (for horizontal gene transfer or as a food source). My question is about where this extracellular ...
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167 views

Electroporation vs gene guns [closed]

What are the pros and cons of using electroporators (left) and gene guns (right) for transformation in terms of: Price Target organism Efficacy Ease of use Maintenance
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Calculating the frequency of a recessive allele in case of three segregating alleles

Is it correct to say: A. f(A) = p; f(a) = q B. p = f(AA) + ½ f(Aa)=$\sqrt{f(AA)}$? Also, For a gene locus segregating more than two alleles, the frequency of each allele is the frequency of ...
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How to find name of the gene

Considering the kegg page, this page contains the description of the gene Edwardsiella tarda EIB202: ETAE_0074 . Now this gene has a name given in the page as : wabG. Now considering another gene 1 ...
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Human Endogenous Retroviruses

I am reading this paper, which shows that a Human Endogenous Retrovirus (HERV) K provirus is present at the orthologous position of gorilla and chimpanzee genomes but absent in the human genome. If ...
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41 views

Animal gene in plants

Usually only microbes, specifically bacteria are used to express genes of other species for various functions. But, it is possible to try and express an animal gene into a plant. Bacteria like ...
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Lac operon: How can lactose enter the cell in the absence of lactose permease?

My textbook states that lactose permease...transports lactose into the cell and When lactose is added to the growth medium, the lactose molecules bind to the other site on the repressor ...
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Question about proto-oncogenes and oncogenes?

My textbook says: Growth-promoting genes are called proto-oncogenes. Some can be changed into oncogenes by a point mutation that alters the ability of the proto-oncogene to be switched off. They ...
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When does a chromatid become a chromosome?

When chromosomes lie on the metaphase plate, they have the characteristic X shape. But these are actually two chromatids that are held together at the centromere. If separation fails and both ...
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Inheritance of Huntington's disease

People with Huntington's disease have HTT genes with more than 37 copies of CAG repeat. The risk of extra copies being generated is higher during sperm formation than during ovum formation. Why is it ...
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Using evolution of bacteria against themselves

We know that mutations happen regularly in bacteria and also that one bacteria might get the mutation and become stronger than the others and thus survive, causing antibiotic resistance as well. Can ...