Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

learn more… | top users | synonyms

1
vote
1answer
26 views

Gene silencing in C. elegans

I am trying to silence the tph-1 (tryptophan hydroxylase) gene in C. elegans using the pLT63 plasmid to check if that particular gene has anything to do with the pharyneal pumping or not. Am I using ...
2
votes
1answer
100 views

Trisomy 21 and Down syndrome

Can Down syndrome occur without trisomy 21 in the karyotype of an individual? Or vice versa can a person have trisomy 21 while unaffected by Down syndrome?
1
vote
2answers
82 views

Is this a simple Hardy-Weinberg problem?

Phenylketonuria is a severe developmental disability due to a rare autosomal recessive allele. Approximately 1 in every 10,000 newborns suffer from this disease. Calculate the frequency of the allele ...
0
votes
0answers
15 views

Color blind animals [duplicate]

So I was reading some bio books and I came upon the fact that dogs and some other animals were color blind, and so I am wondering how do we know. Did we take apart there eye or sequence some of their ...
1
vote
1answer
52 views

Why to use transgenic mice in ALS models?

In ALS mice model with mutant SOD1 - there are use of transgenic mice, with insert of human mutant SOD1. Why is that? Why not to mutate directly mice SOD1 ? In transgenic mice, after few generations ...
0
votes
1answer
29 views

QTL mapping in Drosophila

I have already googled it before but yet unsuccessful in finding the whole topic with intuition. Please help. A guide to an associated book would be greatly valued.
0
votes
0answers
41 views

Are there any arguments against the Onion Test

Are there are any sound arguments (that are simply explained) against the Onion test (http://www.genomicron.evolverzone.com/2007/04/onion-test/)? Which in turn could contribute to the argument that ...
2
votes
3answers
649 views

What is the biological significance of finding palindromes in DNA sequence?

I found a function called palindromes in Matlab that finds palindromes from DNA sequence. Now what is the biological intention behind incorporating this function? What the biological significance of ...
0
votes
1answer
35 views

how does one apply for masters in genetics abroad? [closed]

Please can some one give me step wise instructions for applying for a masters degree in genetics or biological sciences?
1
vote
1answer
34 views

Producing a genetically modified animal with cell walls [closed]

I'm curious if there has been any genetic experiments transferring cell wall producing genes into the genome of a animal model organism such as the fruit fly (Drosophila melanogaster) or a larger ...
0
votes
1answer
31 views

A trivial question on the meaning of “relatives” in an article on horizontal gene transfer

Am I right in suggesting that by close relatives the author meant closely related species, or did he have individual organisms in mind? DETECTION OF HORIZONTAL GENE TRANSFER There are ...
1
vote
0answers
111 views

mutations induced by transposons

Question: In contrast to chemically-induced mutations, mutations induced by transposons are more likely to ... be lethal de dominant be stable revert to wild types be a gain of function The ...
1
vote
2answers
107 views

Why do males have more birth defects? [closed]

I taught in elementary school for 20 years and noticed that males were far more likely to be classified as handicapped than females. More males than females die at birth and are more likely to have ...
2
votes
1answer
86 views

How does Cas9 interact with CRISPR?

I read that Cas9 protein along with guided RNA binds at a specific DNA fragment of foreign organism integrated in a host organism DNA. To make the host immune to virus infection Cas9 along with gRNA ...
1
vote
0answers
28 views

recombination between DNA segments question

In the diagram shown above, segments A and C are copies of a repeated DNA sequence, flanking a unique stretch shown as B. A and C are in an inverted orientation relative to each other, as indicated by ...
1
vote
0answers
31 views

Genotype-Phenotype databases?

Beyond the Stanford HIV database, what other databases out there provide a dataset linking virus/bacterial genotype to quantitative phenotype? I'm looking for high quality datasets to test machine ...
0
votes
1answer
59 views

Are progenies factually half-clones of the parents?

Given that a "clone" (if anything, in the context of human cloning) is taken to be, as far as I have understood, a specimen possessing the same genome as his "father/mother", aren't all "non-cloned" ...
5
votes
3answers
688 views

How does the colinearity of the HOX genes determine the body plan of an organism?

I was recently reading about colinearity in the HOX genes that give an organism its high-level body plan (where the order of the HOX genes on the chromosome follow the head-to-tail order of body ...
3
votes
3answers
131 views

Abbreviations for molecules: What are CheW, CheA, CheY?

I've encountered the abbreviations such as "CheW" and "CheA" for certain organic molecules. For example: Proteins associating with the Tar complex include the autophosphorylating protein kinase ...
1
vote
1answer
30 views

Genetics of Hybrids

I'm working on this problem, but I'm not sure I've done it correctly. My initial thought was that the answer was $D$, but I don't see anything in the above graph that indicated the Hybrid species is,...
1
vote
5answers
2k views

How is incomplete dominance different from codominance?

Ok let me start with the definitions of incomplete dominance and codominance. incomplete dominance - The situation in which the phenotype of heterozygotes is intermediate between the phenotypes of ...
1
vote
0answers
15 views

Serotonin activity with short 5-HTT promotor region and depression

So after reading a few studies (1,2) it seems that a shorter promotor region for the serotonin transport protein may be associated with increased likelihood of developing depression after stressful ...
1
vote
2answers
238 views

How does the sticky ends of foreign gene bind with its counterpart in the plasmid DNA if positions are not matching?

Consider a foreign gene with recognition sequence as GAATTC for EcoR1. Now suppose that it is being cut at two palindromic sequence to form sticky ends. Here the sticky ends are formed such that ...
0
votes
1answer
2k views

How to write 100% phenotype ratio? [closed]

I am not quite sure how to write 100% out come for the phenotype ratio after using "Punnett Square". The result from the each alleles, the dominant allele completely(100%) took over the recessive ...
3
votes
1answer
62 views

What is meant by “the degree to which a gene is expressed” in an individual?

Here is an excerpt from a text that I was reading, Here is an example of microarray data. The idea is to take a group of different individuals and for each of them, you measure how much they ...
2
votes
3answers
948 views

Why don't the apples seeds from grafted trees produce the same kind of apples?

As Wikipedia says: Grafting is a horticultural technique whereby tissues from one plant are inserted into those of another so that the two sets of vascular tissues may join together. In most ...
1
vote
0answers
147 views

Why do my 23andme results only show me as 8.2% Scandinavian? [closed]

I just got my 23andme results back. My paternal grandfather was full Swedish. Shouldn't that make me 25% Swedish? 23andme tells me I'm only 8.2% Scandinavian. Or maybe my father inherited less than 50%...
0
votes
0answers
15 views

Rates of evolution of mitochondrial genes

I am interested in knowing the rates of evolution of different mitochondrial genes (in base pairs per million years) across different taxa. Has there been any publications along these lines ?
1
vote
0answers
64 views

Genetic mapping problem

A prototrophic Hfr strain of E. coli with the genotype trp+ purB- pyrC+ is conjugated with an F- strain with the genotype trp- purB+ pyrC- . The trp gene is known to enter last. The following numbers ...
3
votes
1answer
77 views

How C. Elegans is used for siliencing genes

The experiment that is using C. Elegans to silence the Genes. I have a question about Why and how C. Elegans can use the DNA plasmid that is generated with the gene of interest in the bacteria by ...
1
vote
1answer
55 views

Do the effect of inbreeding depression disappear after the first generation of outbreeding?

An animal that is the result of generations of inbreeding tends to have lower fitness. (More diseases etc.) This is usually explained by harmful but recessive mutations that exist in all populations, ...
1
vote
0answers
45 views

Chance of passing a risk allele to child?

Our genetics professor has posted up working for previous examination answers, but I am unsure that one of his answers is correct. My answer is close but may just be due to co-incidence. Question: ...
7
votes
1answer
843 views

Why is an HIV infection considered “incurable”?

My biology teacher told me that if one caught HIV, they cannot be cured because it was near to impossible to be completely virus-free. She said this was because HIV keeps on changing its glycoprotein ...
2
votes
2answers
435 views

Is the SRY gene the sole responsible of biological male sex?

It's very well known that the Y chromosome is what determines maleness, but more specifically this seems to happen thanks to the SRY gene located on it. Some individuals have an XX karyotype, but ...
1
vote
1answer
39 views

meaning of “initial gene constructions” vs. “under the control of plant promoters” in an article on GM plants

From "Risks from GMOs due to Horizontal Gene Transfer", by Paul Keese: Antibiotic resistance genes have been introduced to GM plants either as part of the bacterial cloning vectors used for the ...
3
votes
0answers
56 views

In what way is ADHD genetic? [closed]

According to Psychcentral depression, bipolar disorder, ADHD, schizophrenia and autism are traceable to the same inherited genetic variations According to AsapSCIENCE, depression could be genetic due ...
2
votes
0answers
512 views

Why does supercoiled DNA run faster?

The DNA exists in linear and cirular forms. The latter form has interesting feature called Supercoiling. The more number of writhe makes it more supercoiled because of which it gets more compact. ...
1
vote
0answers
24 views

Meaning of “pure” in “pure plant DNA” (horizontally transferred to bacteria in soil conditions)

The abstract of Transformation of Acinetobacter baylyi in non-sterile soil using recombinant plant nuclear DNA, by Simpson et al., 2007: To provide estimates of horizontal gene transfer from ...
2
votes
3answers
275 views

Effect of a doubling of the start codon in a gene

I am learning about frame shift mutations. Frame shifts can occur due to a nucleotide deletion. Suppose that due to a frame shift, because of a deletion somewhere upstream from the original start ...
1
vote
0answers
31 views

Will someone with a double mutation in the allosomes be normal?

Normally a female human has an X allosome from her father and an X allosome form her mother. What if an double mutation happened, which causes that someone has two X allosomes form her mother and no ...
4
votes
3answers
2k views

Chromosome 2 fusion?

I read this article by Jeffrey Tomkins and Jerry Bergman claiming to debunk chromosome 2 fusion. Is there anything wrong with these conclusions? " 1.The reputed fusion site is located in a peri-...
0
votes
2answers
241 views

DNA adaptation in human life

Does our DNA adapt by human lifetime? Or do we have the same genetic information from birth to death? I mean: What is usually called "evolution" means "natural selection" like this: http://www.youtube....
0
votes
2answers
119 views

how do I find the number of bp in chromosome 3 by knowing number of bp in chromosome 1?

If i have a number of bp in chromosome 1 for example(298,295,559 bp) can I use this number to find the number of bp in chromosome 3.
1
vote
2answers
80 views

“structural and regulatory elements of genes” [closed]

Can anyone please explain a little about these two elements of genes? My main problem is with "which ‘switch on’ instructions". genes have structural elements (which code for a particular protein) ...
1
vote
1answer
64 views

meaning of “usually greater than 200 base pairs”

From "Risks from GMOs due to Horizontal Gene Transfer", by Paul Keese: Homologous recombination. All cellular organisms have molecular functions dedicated to recognizing and recombining DNA ...
2
votes
0answers
20 views

Why are multiple copies of the 35S enhancer used for overexpression in plants?

I know that the CaMV 35S promoter is widely used for transgenic plants, and I also know that it can be used as an enhancer element for overexpression. I noticed that it is always used as a ...
21
votes
3answers
2k views

120-year-old gene regulation problem independently solved by a computer. How?

My Background: I'm a mathematics graduate student with a physics background. I have a very little biology knowledge and a little knowledge of machine learning and statistics. Topic: I recently ...
0
votes
2answers
761 views

How do two parents, recessive and dominant genes and two complimentary nucleotides end up in one DNA? [closed]

In the basic school, I was taught that half of genome is received from father and another half comes from mother in the form of double-helix DNA, whose first helix consists of dominant nucleotide ...
9
votes
2answers
4k views

Does one parent transmit more DNA to the offspring than the other one?

Does one parent transmit more DNA to the offspring than the other one? Or do both parents always transmit the same amount of genetic material to their offspring? In other words, can a baby be ...
-1
votes
2answers
197 views

If dog's DNA and human's DNA are almost same then can it be said that dogs evolved from humans? [closed]

https://www.youtube.com/watch?v=IbY122CSC5w In this video it is said our DNA matches almost the dog's then it can be also said that dogs evolved from humans. Is it?