Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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How does a plant decide when to grow a branch? [duplicate]

As a plant grows, at some point the first branch forms. As it continues, branches grow new branches, and so on, in a seemingly random way. Is it random, or is it driven by the environment (heat or ...
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423 views

How are the boundaries of a gene determined?

What statistical processes and methods are used by geneticists/molecular biologists to know where one gene starts and one ends?
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Is DNA mutation locally energetically stabilizing the DNA molecule

I am no biologist, but as a physicist, a spontaneous mutation (seen as a chemical transformation) should lower the energy of the system, at least locally. So I wonder if any research has been done ...
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104 views

Phenotypic Variation of cattle - looking for academic sources

Can someone please point me in the direction of a good academic article on the following: What are possible sources of phenotypic variation of different 400 day weights of cattle? Furthermore how ...
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Terminology question: the scope of an allele in an organism

Let us consider a gene FOO with novel type foo. If I were discussing an organism that has inherited foo in every cell during classical zygote formation, then I would ordinarily just say that the ...
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1answer
760 views

What is a focal copy number variation?

Often, genetics studies, especially genome wide ones, talk about "focal copy number variations" in genes or regions of the chromosome. I know what a copy number variation is. What does "focal" mean, ...
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1answer
135 views

Non-monotonic knock-out effects in prokaryotes

Typically, when performing gene-knockout, the experimenters select one gene to remove/replace-with-junk and then see if the prokaryote can still undergo fission. If it continues to reproduce then the ...
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1answer
237 views

What phenotypes can arise from gender-related aneuploidy?

Humans normally have 46 chromosomes (two copies - one from each parent - of each of the 24 chromosomes: [1:22] + [XX or XY]). Aneuploidy is an abnormal number of chromosomes - Down's syndromes is an ...
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1answer
91 views

In a vertebrate chimera, are particular organs homogenous genetically?

I have read that a chimera is an organism with two or more sets of DNA, with every cell having one of the sets. Is it possible and common for the two or more sets to be present in the cells of a ...
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208 views

Do twins “run in the family”?

My wife and I recently found out that we are going to have twins and so nearly everyone asks if we have a family history of twins. Now I know that the answer for me is that it doesn't matter—as ...
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3answers
163 views

Why don't flies avoid the motorway?

Flies have a short lifespan, therefore evolution should technically happen over a shorter period of time (years). Flies die all the time from getting hit by cars on the motorway. Those flies that ...
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1answer
59 views

Can an organism obtaining a part of its genome via horizontal gene transfer be called a “hybrid”?

Wikipedia definition of "hybrid" offers many competing definitions. But most seem to be centered on sexual-reproduction gene transfer. Is there an official (in a textbook or widely accepted peer ...
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What is the frequency of double-hets between parent and child?

Say both parent and child are genotyped for all SNPs. In this setup we are only looking at variant positions between one parent and child - so neither parent nor child are homozygous reference (no ...
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1answer
282 views

Can parents' learned traits be transmitted genetically?

I am wondering whether a behavioral trait (e.g. fear or stress experienced in the lifetime of the parent) can be transmitted genetically to its offspring? I understand that a behavioral tendency for ...
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1answer
54 views

Drosophila reference genome

Does anyone know the details about which line they are using to sequence as the Drosophila melanogaster reference genome?
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2answers
335 views

Is there any reason for the variation in mitochondrial DNA size?

As my textbook An Introduction to Genetic Analysis points out, yeast mitochondrial DNA has approximately 78 kb of genetic data, while the human mitochondrial DNA contains 17 kb. Is there any evolution ...
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1answer
80 views

Predictable microchimerism

I read in New Scientist recently that microchimerism occurs between previously born siblings and grandparents, not just the mother. Do we know which parts of the genome are likely to be transferred? ...
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152 views

Is there an “evolutionary species similarity calculator”?

Is there a website where I can input pairs of species and get an "evolutionary similarity score"? E.g. (numbers are completely made up) Input: Chimp and Human, Output: 97% Input: Cat and Human, ...
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1answer
68 views

What's in a Name: Statistical Genetics

The novice often performs population calculations using what is referred to as Mendelian Genetics. Soon after the publication of Mendel's results; Hardy and Weinberg presented their results after the ...
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effect of background selection on promoter regions compared to distant enhancers?

Has anyone looked at the effect of background selection on the levels of conservation of promoter regions compared to distant enhancers? Do promoter regions have a higher conservation due to ...
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2answers
993 views

Autosomal Recessive Trait when skipping one generation

I learned recently that given a pedigree it is possible to tell whether a disease is autosomal recessive by observing if the trait skips a generation. If the disease does skip a generation, then the ...
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1answer
55 views

What are treatable foetal conditions during pregnancy?

What are different foetal conditions during pregnancy that could be treated with appropriate prenatal genetic testing? I only know that pregnant women are encouraged to take certain supplements to ...
4
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1answer
80 views

Online toolkit that provides functional similarity scores (in the form of a matrix) between two functional gene sets in the context of gene ontology

Where can I find an online toolkit that provides functional similarity scores (in the form of a matrix) between two functional gene sets in the context of gene ontology? I have tried the following: ...
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134 views

Extreme examples of protein translation/use coupling/decoupling?

What are known extreme examples of protein translation/effect coupling/decoupling? For example, examples of proteins that are immediately used at the time the have been translated and vice versa, ...
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1answer
268 views

T7 promoter leakiness

Can a gene be expressed under the T7 promoter in an E. coli strain (e.g. DH5 alpha), which does not have the T7 polymerase gene encoded in its genome? In other words, is T7 promoter leaky? To be ...
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1answer
396 views

Are there examples of the green beard effect in humans?

Green-beard effects are genes that: Produce an effect that can be detected Produce preference to others with the same effect Are there any examples of this in humans?
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4answers
863 views

Why do men have nipples?

I'd be tempted to call nipples in men vestigial, but that suggests they have no modern function. They do have a function, of course, but only in women. So why do men (and all male mammals) have them? ...
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72 views

Relative Property of Alleles

If there are three different alleles to a gene, is it possible that the first is dominant to the second, but recessive to the third?
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What is the relative power of GWAS studies in different species?

I would like to know of any publication studying the relative power of GWAS studies in different species. For example, I've seen reports that say genotyping and GWAS in dog breeds is much more ...
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2answers
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phylogenetic analysis of gene enrichment?

Are there any tools to do phylogenetic analysis of gene enrichment? This is, I have a list of genes from an experiment performed in several species, with a z-score that can be described as ...
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1answer
125 views

Are there any DNA base sequences that are fully conserved between the genomes of all humans?

That is, they don't differ throughout the entire population. I understand of course that we can't DNA sequence every human, so by "fully" I mean there's an incredibly small probability of there being ...
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2answers
81 views

How do proteins and genes participate in learning?

I am a computer scientist that studies biology and bioinformatics. In the last weeks, I have been trying to study new research directions, and I would like to deepen my knowledge on the role and ...
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1answer
87 views

What are Haplogroups?

What exactly does the term Haplogroup or Haplotype means? How is it claimed that people belonging to the same haplogroups have common ancestors?
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Does the word “polymorphism” refer to the gene, the phenotype, or both?

In genetics, does the word "polymorphism" properly refer to genes, to phenotypes, or both? For example, if there are two alleles that lead to differences in the structure of the D2 neuroreceptor, ...
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202 views

Are there dog breeds that are so far apart genetically that they can't produce viable offspring?

Obviously, a very large dog would have difficulties mating with a very small dog and vice versa. But putting that problem aside (using, say, insemination), considering the large variation of dog ...
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Is there a gene that starts meiosis 2?

Yesterday I thought about a question and asked it to my friend. The question was which gene is completely the same for a male cell that made meiosis 1 recently. My answer was the gene that starts ...
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Co-transformation of plasmids from the same incompatibility group

Can two plasmids with the same origin of replication (for example pBR322 ori) and thus from the same incompatibility group be successfully co-transformed in E. coli? What are the mechanisms that would ...
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Have any mutations or genetic loci been associated with exceptional longevity in humans?

Individuals that avoid age-related diseases into later life are known as 'exceptional survivors', and have increased longevity compared to their 'controls' (those that were born at a similar time, yet ...
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Gametes of two different species

I always wondered why gametes from two different species dont fuse together to form an offspring. eg a donkey (sperm) and a female dog (egg) I know this is not possible but I'm just curious.
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How many pandemic H1N1 2009 virus sequences were submitted by the Indian NIV as of May 10, 2010? [closed]

The handout I was following is maddening. It says; "Go to the NCBI home page and select 'All Resources (A-Z)' and choose GenBank. Follow the NCBI Flu Resource link to determine how many pandemic H1N1 ...
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285 views

Number of beneficial mutations cataloged?

I can see from Wikipedia that there are possibly thousands of harmful mutations that have been cataloged and linked to disease. There are also unnumbered neutral mutations. But, does anyone know how ...
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1answer
457 views

What generates variation in a species?

What is the biological mechanism behind the variation within sexually reproducing species? Obviously, the children are combinations, to differing degrees, of their parents. But how does the variation ...
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1answer
93 views

obesity risk and single gene polymorphisms

I read a fairly recent meta-analysis of studies into the association between adult obesity and polymorphisms of the FTO gene (Peng et al., 2011). The paper looked at 59 studies and found that "FTO may ...
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1answer
198 views

Predicting progeny of recessive mutations using recombination

I was asked this question on a test and got it wrong, but I'd like to know how to do it. The answers are shown in the blanks below: You are studying two recessive mutations in the fruit fly D. ...
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1answer
95 views

What exactly is meant by the expression “differentially expressed”?

As far as I've seen, this expression is almost always used in relation to gene expression profiling. Unfortunately, I have no background in this area. Can someone please explain this in layman terms?
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Determine which gene is in the middle complementation [duplicate]

Possible Duplicate: Crossing mutant strains on minimal media problem I'm studying this problem for my genetics final: My Attempt: The answer for part B is met2 and the answer for part C ...
5
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1answer
630 views

The genetic and physiological origins of laughter?

This Wikipedia article defines laughter in many terms, such as... "a visual expression of happiness, or an inward feeling of joy" and "a part of human behavior regulated by the brain, ...
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95 views

How to find Dmax (genetics problem) [closed]

My attempt: I'm not sure this is right but this is what i did. I found the allele frequencies to be: A=0.4 B-0.3 a=0.1 b=0.2 I think to find Dmax I just multiply the two alleles with the larges ...
8
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1answer
102 views

Why can't we breed watermelons without any remaining seeds in the flesh?

Watermelon is just starting to come in season in the northeastern U.S., and having a seedless watermelon is convenient. The only downside is, the "seedless" almost always still have the immature, ...
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1answer
187 views

Finding DNA from Amino Acid sequence problem

My attempt: First I took the single letter AA codes and made them amino acids. So, the first one is Trp which is 5'-UGG-3'. From this I got the DNA sequence 3'-CCA-5'. However, the correct ...