Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

learn more… | top users | synonyms

1
vote
1answer
44 views

psychological database with sequenced DNA records

I'm looking for an epigenetic database which includes for each example the psychological history of the persons DNA. Right now I can only find DNA and epigenetic databases. Sadly none of the databases ...
2
votes
1answer
54 views

How did the Chromosome #2 Fusion propagate?

There is strong evidence that chromosome 2 in humans is a fusion of two chromosomes of a common ancestor of chimps and humans as explained at wikipedia here Was it necessary for the common ancestor ...
14
votes
2answers
5k views

How many people are required to maintain genetic diversity?

Imagine humans were to colonize a distant planet and it was a single one-way trip. How many people would they need to bring? Obviously 2 is the minimum, but that would result in a lot of inbreeding. ...
6
votes
2answers
176 views

does order of genes in a chromosome matter?

does the order of genes within a chromosome matter? or is the main thing that the genes are there. so for example, our DNA is very similar to that of apes not only by the genes themselves but also by ...
1
vote
2answers
123 views

Heterochromatin binding sites position information

I am working on a project and I'm trying to find data on the position of genes and heterochromatin binding sites such as HP1 in Drosophila melanogaster. Is this information available for the DGRP ...
0
votes
3answers
96 views

can recessive alleles produce codominance?

Maybe I'm confused by the term "codominance", but I wondering if codominance only occurs with two dominant alleles. Can two recessive alleles produce codominance in an individual? Likewise, can two ...
0
votes
1answer
134 views

what is the biggest known functional distance between an enhancer and its target gene (TSS) in cis?

since the title seems self explanatory; It would be nice if anybody could provide a reference. I'm looking for a paper that I belive stated around 1.5 Mb but anything above will be cordialy welcomed. ...
1
vote
1answer
251 views

Convert gene name to uniprot ID

i have a list of gene name in a file CHRNB2 EGR2 GCK KRT14 LMNA FGF3 TK2 ABCC8 How can I map them to uniprot ID ? P.S I tried Uniprot "ID mapping" ...
9
votes
1answer
217 views

How are new people created from the DNA of an aged person. i.e. Why are we young?

The question "why do we age" has been asked numerous times. But why are we young? The cells of the adult human being are an age (time>0), but how can old cells create new cells that are younger than ...
2
votes
1answer
69 views

Could an annual plant be genetically modified to be a perennial?

My chives, asparagus, oregano, and rhubarb come back every year like clockwork. Suppose I want my bok choy to join the party - is there an "I'll be seeing you next year!" gene that can be modified to ...
1
vote
1answer
80 views

Recombination-based vs. Sequence-based genetic mapping

Now that sequencing is becoming increasingly cheap, what is the value of recombination-based genetic mapping against the sequence-based genetic mapping? I think that in the past recombination-based ...
3
votes
1answer
555 views

What is the purpose of back-crossing mice for multiple generations?

Occasionally I will come across articles that refer to back-crossing mice of one strain onto the background other another strain (e.g., C57Bl6). They do not explicitly state the purpose for doing so, ...
2
votes
0answers
58 views

Can a heterozygous allele show non-heterozygous expression in a family?

I'm doing a family study looking for novel cancer-associated variants in germ-line samples; the goal is to find candidate biomarkers which might be used for early detection. At an earlier step our ...
2
votes
2answers
126 views

What is doubling of genetic material invented in flowering plants?

David Attenborough in his Kingdom of Plants 3D said, that flowering plants made two inventions: (1) doubling of genetic material and (2) symbiosis with animals. What was meant by "doubling of genetic ...
6
votes
1answer
1k views

what is the difference between “cistron” and “gene”

I'm asking after reading the cognate wikipedia.en article on "cistron". I still am not sure about the difference of the two terms. To me it seems valid to picture a "cistron" as the genome wide set ...
0
votes
1answer
113 views

Pedigree analysis : autosomal or mitochondrial

I have tried a to decide if this is a autosomal dominant, recessive or a mitochondrial disorder. Is it possible to know for sure, or do you have to use probability? (English is not my native ...
20
votes
1answer
696 views

Do trees age on a microscopic level?

Most animals age via at least two mechinisms: at a "macroscopic" level, basically wear and tear to the point where (on evolutionary time scales) it's more genetically advantageous to optimize for ...
5
votes
2answers
8k views
2
votes
2answers
52 views

Valid comparison of gene expression between several genes in several cell lines

We have gene expression data (Affimetrix mRNA gene expression results) for several cell lines, over a set of genes. Our goal would be to be able to compare relative gene expression for genes over the ...
2
votes
2answers
143 views

Can someone who is color blind recover color vision by surgical means?

I am currently studying color blindness, and there is no medicine that can help it. Is it possible nonetheless for someone who is color blind to have their eyes restored to normal color vision by ...
1
vote
1answer
23 views

Primers on Dystonia

Where can I get a good biochemical overview of dystonia? I will be working in a research lab that focuses on dystonia and I would like to not be clueless.
3
votes
1answer
59 views

Mode of inheritance - DYT1 Dystonia

Homozygous DYT1 mutation carriers have not been reported in humans. Does this mean that the mode of inheritance for dystonia (DYT1) is autosomal dominant? This to me implies that if one has both ...
2
votes
2answers
312 views

What are these strings used to describe animals?

For example, what's a $dt^{sz}$ hamster? (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1144494/). What's a Rgs9-Cre/+;gtROSA/+ mouse? ...
2
votes
1answer
44 views

Does the most common definition of “allele” include a change in phenotype?

I'm prepping an activity for my biology students on cystic fibrosis. There are about 2000 different mutations of the CFTR gene that cause CF. Since the final phenotype is pretty much the same, can I ...
1
vote
1answer
49 views

What is the close and related genome used for in Gene models?

all I am a little bit confused about using the related genome or reference genome. When we have a reference genome, we can do alignment. Also we can do the assembly. Can you give some more reason ...
10
votes
4answers
11k views

Do we get 1/4 of our genes from each grandparent?

I know that we get half of our genes from each parent, but does it necessarily mean we get 1/4 of our genes from each grandparent? Or is it possible that we might get say 30% from one grandparent, 20% ...
4
votes
1answer
146 views

Epistasis Involving Multiple Loci

The following problem is from Schaum's Outlines on Genetics, 5th edition, by Elrod and Stansfield. I'm having some trouble solving it. It is found under a section entitled "Interactions with Three ...
1
vote
1answer
74 views

Religion and Genetics

Are there studies that investigate the heritability of believing in supernatural things (or related concepts)? Or stated differently. Are there studies that ...
2
votes
1answer
42 views

What does “regulatory genomics” mean?

I have read about basics of molecular genetics ,although its not a thorough in-depth knowledge. I would like to know about "regulatory genomics". What is it actually?
4
votes
2answers
122 views

A photosynthesizing mouse?

N. Shubin's Your Inner Fish makes the point several times that there is a lot of functional similarity between some seemingly remote gene cousins. If that needed reinforcing we have the spider-goat, ...
1
vote
1answer
30 views

Property of E.coli harboring F element

From Genetics by Ursula Goodenough E.coli harboring an F element are endowed with a number of phenotypic traits : 1.They are sensitive to infection by ssRNA phages and certain ssDNA phages. ...
1
vote
1answer
49 views

Distribution of fitness in wild populations

If I get out in the wild observe wild populations and measure the distribution of fitness $f(w)$ in a given population. What will I find out? Will I observe a Gaussian distribution, a Poisson ...
5
votes
3answers
249 views
4
votes
3answers
10k views

Evolutionarily speaking, why do humans have 46 chromosomes

In humans, each cell normally contains 23 pairs of chromosomes, for a total of 46. Monkeys, chimpanzees, and Apes have 24 pairs (twenty-four pairs), for a total of 48. What caused humans to have 46? ...
7
votes
1answer
502 views

On average how many genes / alleles do people share?

I am curious about how much more a child can be alike to one parent than the other. If a child were to inherit all the alleles that are shared between both parents from one parent, but inherit all ...
4
votes
2answers
7k views

Why do ladybugs have a different number of points on their backs

Everytime I see a ladybug I ask myself this question. Why does every ladybug have a different amount of points on its back? Is it because of its age? Or because of its genes? Is it inheritable?
2
votes
3answers
856 views

Genetics: pedigree following a rare trait autosomal recessive

I have two questions pertaining to this pedigree I believe it to be an autosomal recessive trait. The probability that individuals IV-1 and IV-2 would give rise to an affected individual would ...
1
vote
3answers
90 views

Definition of species - location of gene

I know that species have been classified on basis of reproduction , DNA similarity , niche, etc. Has there been a classification based on locus of genes ? What are the drawbacks/shortcomings of ...
1
vote
2answers
133 views

Gene perturbation, what is it used for, explain to computer scientists? [closed]

I am trying to build a gene regulation network, and I need some basic knowledge of it. So, in gene research, we perturb genes. Such as knock down them? Can people tell 2 or 3 experiment methods to ...
2
votes
1answer
48 views

Drosophila grey / yellow

I am studying biology by myself via distance-learning. I have been trying to solve the following problem for a while now and hoped you could help me. As this is "homework" I would appreciate hints ...
2
votes
2answers
67 views

In genome research, what is the problem in Mapping that may be caused by reads being too short?

In the following scenario: You were given short sequence reads of plant RNA obtained from a next-generation sequencing machine (fragments of 20–30 nucleotides in length). You attempt to map them back ...
0
votes
1answer
38 views

What information do microarray image convey?

OK I have read that a cell generates 4 kinds of digital (to be precise discrete) data namely DNA, RNA, Protein (sequences that can be encoded as string sequences of nucleotides/ amino acids) and micro ...
0
votes
0answers
55 views

What is the current scientific position on the issue of human race? [duplicate]

Race is perhaps one of the most controversial and sensitive issues in anthropology, biology, and other related fields. As a non-scientist, I've used google to probe the disparity between the positions ...
1
vote
1answer
53 views

Is there a possibility that medicine will affect the efficiency of natural selection?

I mean, saving sick people means that they possibly can propagate something that nature does not allow. I know that there is already something that operate at genetical level producing alteration, ...
3
votes
1answer
126 views

Do there exist publicly available Genome sequences of a family?

I would like to explore the genome sequence of a publicly available genome sequences of a family (like mother, father, son, daughter...). If such human genome sequences are not publicly available at ...
2
votes
1answer
140 views

What does chromosome CHR_Un, CHR_MT in the ftp site of NCBI mean?

I am not a biologist. But need some genetic data. So I searched internet and reached NCBI's website. I came to know from the FAQ page that I can the complete genome data of organisms from ...
5
votes
2answers
417 views

Correlation between genome size and mutation rate?

Martin Nowak in his book "Evolutionary Dynamics" talks about a given correlation between genome size and mutation rate. What correlation does exactly exist between these two concepts? Is it a ...
1
vote
0answers
118 views

Why only able to close one eyelid? Genetic reason?

Eye-dominance is a critical thing with bows: right-eye-dominant is recommended to do the aiming on the right eye here otherwise inaccuracy. This made me think whether all people are even able to do ...
3
votes
3answers
159 views

Help explain multi alleles in terms of actual genetic code

I understand that someones genetic makeup at an allele is usually denoted as (AA,Aa,aa). That means that instead of an A-T pair you get a C-G pair on none, 1 or 2 copies. Now, what exactly happens ...
2
votes
0answers
34 views

examples of chromosomal aberrations with lack of sexual chromosomes?

Are there any examples in animals where individuals survive having no copies of their sexual chromosomes?