The entirety of an organism's hereditary information.
2
votes
0answers
27 views
What does conditional analysis of a SNP in a GWA study entail?
I am familiar with the use of tag-SNPs in genome-wide association studies to identify gene loci involved in complex traits, but I keep seeing the term "conditional analysis" used without any ...
6
votes
4answers
160 views
Chromosomes are of different size but why do all chromosomes have similar GC percentage?
When I browsed NCBI I saw a pattern: even if the chromosome sizes, number of genes, and number of proteins are different, GC% in chromosomes tend to be similar. The examples are linked below.
Yeast,
...
0
votes
1answer
81 views
What is the advantage of circular genomes for bacteria and linear genomes for other organisms?
Bacterial are a great group of organisms. They have circular genomes and never went toward linear genomes while other organisms show the opposite strategy and don't have circular genomes (disregarding ...
0
votes
1answer
59 views
Would two species of yeast with similar genome sizes have the same number of genes or chromosomes?
Similar organisms generally have similar genome sizes. Given this, would two species of yeast have the same number of genes and chromosomes?
Edit: Fixed with thanks to @daniel-standage
2
votes
1answer
30 views
Is There An Initiative To Sequence The Genomes Of Critically Endangered Species?
I realize that there are many isolated efforts to sequence the genome of a particular endangered species such as the orangutan or the snow leopard. However is there a concerted effort to sequence the ...
3
votes
2answers
139 views
Why is the frog genome so much larger than a fish's?
As we have heard in the summaries of the human ENCODE project, 80 per cent of junk DNA appears to have an essential function. Many fish have a genome with only one tenth the size of a usual vertebrate ...
4
votes
1answer
45 views
Drosophila reference genome
Does anyone know the details about which line they are using to sequence as the Drosophila melanogaster reference genome?
6
votes
0answers
57 views
DNA modifications other than 5-mC/5-hmC/5-fC/5-caC in vertebrate genomes?
Other than 5-Methylcytosine and the more recently discovered 5-Hydroxymethyl, 5-formil and 5-carboxylcytosine DNA modifications found in DNA sequences, what are other DNA modifications present in ...
6
votes
1answer
338 views
Examples of intracellular parasites of medical or economic importance?
What are examples of intracellular parasites of medical or economic importance? I have read that Xanthomonas oryzae is an intracellular parasite in rice that produces proteins able to cause changes in ...
1
vote
1answer
51 views
TFBS predictions for yeast and pombe?
Are there any resources out there for TFBS (transcription factor binding site) predictions for the yeast (S. cerevisiae) and S. pombe genomes? Even if these are only de novo predictions, I would like ...
4
votes
0answers
23 views
harvesting fertilized eggs from Tetraodontidae species?
I would like to know how easy/difficult it is to harvest fertilized eggs from Tetraodontidae species such as Tetraodon nigroviridis or Takigufu rubripes compared to zebrafish? Ultimately, I would like ...
10
votes
2answers
65 views
determining genome-wide exogenous binding of pathogens to host genome?
I've read this paper where they specifically modify a region in the rice genome to ablate the binding site of a pathogen, Xanthomonas oryzae, and disrupt the hijacking of a gene network in the rice ...
15
votes
2answers
659 views
Which organism has the smallest genome length?
Which animal/plant/anything has smallest length genome?
9
votes
1answer
86 views
Chicken Genome what are the LGE 'chromosomes'?
The chicken genome identifies two "LGE" sequences in the chicken genome. Are these distinct chromosomes or some highly variable sequence from the genome that is put in a separate sequence? I'm ...
