The study of blood, the blood-forming organs, along with blood diseases and their treatment.

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Do females living on mountains have more RBCs than a normal male [closed]

I got this doubt when I was studying about haematocrit value. According to my NCERT textbook males have greater number of RBCs than females. But who will have more RBCs when comparing a normal male ...
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1answer
40 views

Carbon Monoxide and High-Oxygen-Affinity Varieties of Hemoglobin

I recently learned about the concept of "affinity" in regards to hemoglobin. For hemoglobin in humans, carbon dioxide has a lower affinity than oxygen, which allows gas exchange to occur in our lungs. ...
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34 views

Can lymph be in peripheral blood?

I read an argument that 1-3% of lymph is in peripheral blood. However, I am not sure if this lymph is about lymphocytes in peripheral blood; not lymph itself. Lymph gets exchanged between capillaries ...
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23 views

Plateletpheresis for hemophilia

Plateletpheresis is seperation of platelets from whole blood and putting the leukocytes and erythrocytes back into the blood. If the person donating platelets does not have hemophilia than could a ...
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42 views

Blood consumption

Is consumption of blood more "dangerous" compared to meat? There was a news-article about unnatural chemicals found in the blood of mothers. This reminded me about a question I have pondered upon ...
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64 views

Blood Type Compatibility [closed]

It should be that because O+ blood(which is my blood type) has all antibodies but no antigens that all other blood types including O- would be incompatible making O not a universal donor so why is O ...
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1answer
36 views

Protoporphyrinogen (IX) formation in heme synthesis

This picture shows one of the steps of heme synthesis. In this step two propanoate groups of coproporphyrinogen III are decarboxylated to form protoporphyrinogen IX. The enzyme that catalyses this ...
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237 views

Why does hemoglobin's affinity for oxygen increase if an organism lives at a higher elevation where oxygen is lower?

Wouldn't its affinity for oxygen decrease because the acidity of the body would increase with the lack of oxygen? The textbook said otherwise though and I don't understand.
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59 views

Why are red blood cells considered to be cells?

Wikipedia states that a cell is the basic structural, functional and biological unit of all known living organisms. Cells are the smallest unit of life that can replicate independently. It then ...
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84 views

What actually are the blood groups for human being?

We all know that, Human blood groups are of 4 types with Negative and Positive of each types. The Wikipedia article also states so. But according to this forum thread there are some other types too: ...
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45 views

Trauma, blood loss and thirst

Back story. Watched an episode of Arctic Air, (season three episode six), where they are practicing and hoping to become a licensed search and rescue airline. Anyhow; two hikers gets attacked by a ...
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77 views

Why do so many people have group O blood?

Please forgive me in case my question wouldn't make much sense. I was reading about ABO blood groups on Wikipedia, where I learnt that O is a recessive allele, and that it seems the A allele predates ...
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1answer
23 views

Detecting a Fasting State in the Body via Lasers

I was just wondering wether it would be possible to detect if the body is in a "fasting" state, via lasers attached to the body. If it is possible, what sort of laser would be needed?
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24 views

Does apheresis damage any components of blood? If not, why not?

Blood donation involving apheresis is becoming increasingly common. It looks like the process involves centrifuging blood at very high speeds* before removing the desired fraction and returning the ...
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1answer
29 views

What is the function of clot retraction?

I am thinking how clot retraction and fibrinolysis work together. I think that clot retraction is a process that gets clot towards fibrinolysis process. Fibrinolysis process then lyses the clot. ...
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1answer
16 views

Association of shorter telomeres with heart disease

From this paper Those with shorter telomeres in blood DNA had poorer survival, attributable in part to a 3.18-fold higher mortality rate from heart disease (95% CI 1(.)36-7.45, p=0.0079), and ...
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1answer
45 views

probability of having normal daughter

If father has hemophilia, mother is a carrier of the disease, then what is the probability of having a normal daughter ? My question: Should the probability of having a daughter be also ...
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1answer
63 views

Prothrombin time when extrinsic pathway is turned off

I was searching for an answer that "why do we need intrinsic pathway when there is fast extrinsic pathway" and i found the answer in the following link: http://www.pathologystudent.com/?p=3197 It ...
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1answer
86 views

Why do you need the intrinsic pathway when you have faster extrinsic pathway?

There are two pathways in blood clot fromation; the extrinsic pathway and the intrinsic pathway. The extrinsic pathway is faster than intrinsic pathway because it has less number of steps. So, why do ...
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0answers
29 views

Events after Endothelial interruption

What are the physiological events that occur after there is endothelial interruption in the blood vessel? What does endothelial interruption mean here? And what could be the physiological events?
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90 views

Rh factor and dominance of gene

"Formation of Rh antigen is controlled by dominant gene(R) and its absence by recipient gene(r).People having this antigen with genotype (RR or Rr) are called Rh positive and those whose blood ...
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1answer
51 views

Blood group probability question

My answer ( after rounding off) is 9% -100( 0.75 X 0.25 X 0.5) but the answer given is 22 % Am I correct ?
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1answer
334 views

Why is prothrombin time test not used for heparin

Prothrombin time test is used for the monitoring of warfarin but not heparin. Why is this used for warfarin monitoring and why is it not used for heparin monitoring?
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90 views

Why isn't RH disease present in other mammals?

Basically, I have read about RH disease, Its rare but it can happen when an RH + baby is conceived by an RH - mother. This raises many questions. I have heard this problem only happens with humans, ...
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1answer
147 views

How do proteins get into the blood stream?

So I'm asking this in reference to the injection of insulin, which is commonly done subcutaneously (in the hypodermis, a fatty part of skin). Now I know proteins usually get into the blood when ...
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1answer
1k views

Why does Blood clot outside the body? [closed]

The blood does not clot inside the body due to anti-coagulants. Why does it clot outside the body? For example; when the blood is taken in a tube, it clots after some time, why? Yes, a deficiency of ...
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0answers
41 views

Tonometered blood and the mixing technique?

I am writing an assay about HbA affinity in one specific bird species. In the paper I've read mixing technique is used to determine the P50 values. Can someone explain me this technique and what is ...
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1answer
22 views

External tissues, connected to the body?

Some cancer tumors suppress themselves from spreading. When such tumors are removed by surgery, the metastasis process is accelerated. Isn't it possible to put such tumors into external device like ...
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1answer
36 views

Cellular components of blood cells

There are different types of blood cells in the human body i.e. red blood cells, neutrophils, basophils, eosinophils, monocytes, T-cells, B-cells. What are the cellular components of these cells? ...
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958 views

Presence of MHC on red blood cells

Do red blood cells have no MHC? (I have often heard that they do not.) If so why are they not destroyed by immune cells?
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1answer
739 views

What happens if an IV drip with a saline solution slips out of the vein, but keeps dripping into the body?

A patient has a saline solution IV drip into the vein. They have somehow moved around and the needle has fallen out of the vein, but remained in the body. Nobody has noticed and for a few hours water ...
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1answer
168 views

Does a blood transfusion cure disease?

Does transferring blood between two people also transfer all the white blood cells? Why can't AIDS victims with low t-cell count just get blood transfusions till they have more t-cells? Why can't ...
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1answer
114 views

Does Blood Loss Shorten Telomeres?

If blood loss necessitates immediate cell division to replace lost cells, does the increase in cell division correlate to shortening of telomeres? Does it further cause the Hayflick Limit to be ...
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1answer
65 views

When was the purpose of bone marrow discovered?

I'm currently reading William Cheselden's book Osteographia or The Anatomy of the Bones, which was published in 1733 (for the pretty pictures, naturally; not up to date anatomy). When he addresses the ...
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54 views

Biological/molecular basis of nutritional need differences between blood types?

There are many nutrition books and websites (like http://www.aqua4balance.com/Healthy-Diet/blood-type-nutrition-educational-workshop.html) that assign very different nutritional needs to individuals ...
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What is the genetic basis of blood type (ABO) system?

What is the genetic basis of the A/B/B+/O/etc. blood type system? Are there definitive loci that correspond to each or can multiple different genotypes produce the same antigen profile? Also, is the ...
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392 views

What is the best color for a PPG signal (photoplethysmography)?

What is the best color for a PPG signal? Red, green, blue or infra-red? I'm asking because commercial oximeter sensors usually use a pair of red and infra-red LEDs. But recently, I've seen a lot of ...
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581 views

Antigen Antibody reactions during blood donation

A person wih blood group O is called a Universal Donor. Well, his plasma contains antibodies A and B. During blood donation, if blood group O is given to a person with blood group A (since blood group ...
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1answer
37 views

What Effect would Cannabinoids have on the Acute Porphyrias?

I should be clear in saying that this question is NOT intended for personal medical advice. Rather what I am looking for is journal articles and/or books that touch on this subject because I think it ...
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1answer
57 views

Why don't individuals with sickle cell trait suffer from sickle cell anemia?

Ostensibly, in people with sickle cell trait, half of the hemoglobin in their body would be defective. Is it actually the case that sickle cell hemoglobin is produced in equal amounts? If not, how ...
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1answer
94 views

Is it possible to condition the body to reduce bruising?

I do combat sports, and in these sports there are a lot of hits that can cause bruising. I've found that, over time, physical conditioning can reduce and/or eliminate the bruising to the point where ...
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1answer
1k views

Why does oxygen bind to hemoglobin in an specific angle?

There is an specific angle of the bond between oxygen and hemoglobin in lungs, which I don't know, but what interests me more is the question, why is it specific?
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1answer
135 views

Can antibodies be formed against white blood cells after blood transfusion?

If antibodies are produced against other blood groups' red blood cells, why can't antibodies form against white blood cells, of any blood group? (even the same one, as MHC will be different in almost ...
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1answer
597 views

Why does blood come from mouth when people are shot in the chest area?

In almost every movie scene when a character is shot in the chest area, some blood comes from his mouth or sometimes even coughs blood before he dies. Are these kind of scenes realistic/possible? If ...
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1answer
67 views

Why it is so difficult to treat leukemia?

I want to ask what is the reason that T315I type CML leukemia is currently untreatable. I have read quite a few papers in this subject. Why the current genetic oriented engineering drugs failed to ...
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92 views

How is a blood sample analyzed to give the different levels of metabolites?

How is a blood sample analyzed to give the different levels of metabolites? Are there any any procedural differences with each blood test? Thanks in advance!
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396 views

Iron deficiency anemia symptoms explanation

In my classes and on the internet, brittle nails and dry hair (or hair loss) are described as symptoms of iron deficiency anemia, but none explains the cause of such symptoms. Does anyone have any ...
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1answer
931 views

How much does donating blood affect the amount of oxygen in your blood stream at high altitude?

I am a regular blood donor and I am also a skydiver. We normally go to around 13,000 feet AGL (above ground level). Depending on how high above sea level the ground is, altitudes could be as high as ...
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1answer
147 views

How can the child and the mother have different blood types?

As far as I know the fetus is fed by the umbilical cord which basically connects his/her circulatory system with the mother's in order to supply oxygen and nutrients. But how is this possible if they ...
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4k views

Why do people have antibodies against other blood types?

The ABO blood type divides each blood type according to whether they have the "A" and "B" antigen(s) (AB has both, O has none). People also have antibodies against the antigens they don't have (AB has ...