The study of blood, the blood-forming organs, along with blood diseases and their treatment.

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Origin, or source, of rhesus negative in human blood

This is my first post here, so please be gentle. I recently learned that I have Rh- blood (I'm A-), and was idly looking into blood types on Wikipedia. I was surprised to find that relatively few ...
21
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3answers
34k views

Why do mammalian red blood cells lack a nucleus?

How did the red blood cell in humans get to lose its nucleus (and other organelles)? Does the bone marrow just not put the nucleus in, or is it stripped out at some stage in the construction of the ...
30
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4answers
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Is there any advantage to one blood type over another?

All humans can be grouped into ABO and Rh+/- blood groups (at a minimum). Is there any advantage at all to one group or the other? This article hints that there are some pathogens that display a ...
8
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1answer
214 views

Does the oxygen concentration equilibrate between red blood cells in the liver sinusoids?

In the sinusoids of the liver, venous blood from the hepatic portal system mixes with arterial blood from the hepatic arteries. Do oxygen molecules move between oxygenated RBCs and non-oxygenated ...
9
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1answer
194 views

What are the clotting factors' effect on avascular necrosis development?

Do clotting factors tpa and pai-1 lead to degenerative osteoarthritis in the same way that lupus anticoagulant and prothrombin might? Is one of these pathways particularly detrimental during formation ...
21
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1answer
610 views

Are lymphocyte sizes clustered in two groups?

Tortora writes in Principles of Anatomy and Physiology: Lymphocytes may be as small as 6–9 μm in diameter or as large as 10–14 μm in diameter. Those ranges are quite close to each others. Should ...