The study of blood, the blood-forming organs, along with blood diseases and their treatment.

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Does Blood Loss Shorten Telomeres?

If blood loss necessitates immediate cell division to replace lost cells, does the increase in cell division correlate to shortening of telomeres? Does it further cause the Hayflick Limit to be ...
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22 views

Detecting a Fasting State in the Body via Lasers

I was just wondering wether it would be possible to detect if the body is in a "fasting" state, via lasers attached to the body. If it is possible, what sort of laser would be needed?
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98 views

Why is prothrombin time test not used for heparin

Prothrombin time test is used for the monitoring of warfarin but not heparin. Why is this used for warfarin monitoring and why is it not used for heparin monitoring?
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Does apheresis damage any components of blood? If not, why not?

Blood donation involving apheresis is becoming increasingly common. It looks like the process involves centrifuging blood at very high speeds* before removing the desired fraction and returning the ...
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17 views

What is the function of clot retraction?

I am thinking how clot retraction and fibrinolysis work together. I think that clot retraction is a process that gets clot towards fibrinolysis process. Fibrinolysis process then lyses the clot. ...
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13 views

Association of shorter telomeres with heart disease

From this paper Those with shorter telomeres in blood DNA had poorer survival, attributable in part to a 3.18-fold higher mortality rate from heart disease (95% CI 1(.)36-7.45, p=0.0079), and ...
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69 views

Rh factor and dominance of gene

"Formation of Rh antigen is controlled by dominant gene(R) and its absence by recipient gene(r).People having this antigen with genotype (RR or Rr) are called Rh positive and those whose blood ...
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41 views

Prothrombin time when extrinsic pathway is turned off

I was searching for an answer that "why do we need intrinsic pathway when there is fast extrinsic pathway" and i found the answer in the following link: http://www.pathologystudent.com/?p=3197 It ...
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4k views

Origin, or source, of rhesus negative in human blood

This is my first post here, so please be gentle. I recently learned that I have Rh- blood (I'm A-), and was idly looking into blood types on Wikipedia. I was surprised to find that relatively few ...
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36 views

probability of having normal daughter

If father has hemophilia, mother is a carrier of the disease, then what is the probability of having a normal daughter ? My question: Should the probability of having a daughter be also ...
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11k views

Why do mammalian red blood cells lack a nucleus?

How did the red blood cell in humans get to lose its nucleus (and other organelles)? Does the bone marrow just not put the nucleus in, or is it stripped out at some stage in the construction of the ...
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54 views

Why do you need the intrinsic pathway when you have faster extrinsic pathway?

There are two pathways in blood clot fromation; the extrinsic pathway and the intrinsic pathway. The extrinsic pathway is faster than intrinsic pathway because it has less number of steps. So, why do ...
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28 views

Events after Endothelial interruption

What are the physiological events that occur after there is endothelial interruption in the blood vessel? What does endothelial interruption mean here? And what could be the physiological events?
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43 views

Blood group probability question

My answer ( after rounding off) is 9% -100( 0.75 X 0.25 X 0.5) but the answer given is 22 % Am I correct ?
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116 views

How do proteins get into the blood stream?

So I'm asking this in reference to the injection of insulin, which is commonly done subcutaneously (in the hypodermis, a fatty part of skin). Now I know proteins usually get into the blood when ...
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47 views

Why isn't RH disease present in other mammals?

Basically, I have read about RH disease, Its rare but it can happen when an RH + baby is conceived by an RH - mother. This raises many questions. I have heard this problem only happens with humans, ...
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608 views

Why does Blood clot outside the body? [closed]

The blood does not clot inside the body due to anti-coagulants. Why does it clot outside the body? For example; when the blood is taken in a tube, it clots after some time, why? Yes, a deficiency of ...
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33 views

Tonometered blood and the mixing technique?

I am writing an assay about HbA affinity in one specific bird species. In the paper I've read mixing technique is used to determine the P50 values. Can someone explain me this technique and what is ...
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21 views

External tissues, connected to the body?

Some cancer tumors suppress themselves from spreading. When such tumors are removed by surgery, the metastasis process is accelerated. Isn't it possible to put such tumors into external device like ...
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6k views

Is there any advantage to one blood type over another?

All humans can be grouped into ABO and Rh+/- blood groups (at a minimum). Is there any advantage at all to one group or the other? This article hints that there are some pathogens that display a ...
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33 views

Cellular components of blood cells

There are different types of blood cells in the human body i.e. red blood cells, neutrophils, basophils, eosinophils, monocytes, T-cells, B-cells. What are the cellular components of these cells? ...
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593 views

Presence of MHC on red blood cells

Do red blood cells have no MHC? (I have often heard that they do not.) If so why are they not destroyed by immune cells?
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117 views

Can antibodies be formed against white blood cells after blood transfusion?

If antibodies are produced against other blood groups' red blood cells, why can't antibodies form against white blood cells, of any blood group? (even the same one, as MHC will be different in almost ...
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963 views

Why does oxygen bind to hemoglobin in an specific angle?

There is an specific angle of the bond between oxygen and hemoglobin in lungs, which I don't know, but what interests me more is the question, why is it specific?
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450 views

What happens if an IV drip with a saline solution slips out of the vein, but keeps dripping into the body?

A patient has a saline solution IV drip into the vein. They have somehow moved around and the needle has fallen out of the vein, but remained in the body. Nobody has noticed and for a few hours water ...
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3k views

Why do people have antibodies against other blood types?

The ABO blood type divides each blood type according to whether they have the "A" and "B" antigen(s) (AB has both, O has none). People also have antibodies against the antigens they don't have (AB has ...
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849 views

What is the genetic basis of blood type (ABO) system?

What is the genetic basis of the A/B/B+/O/etc. blood type system? Are there definitive loci that correspond to each or can multiple different genotypes produce the same antigen profile? Also, is the ...
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126 views

Does a blood transfusion cure disease?

Does transferring blood between two people also transfer all the white blood cells? Why can't AIDS victims with low t-cell count just get blood transfusions till they have more t-cells? Why can't ...
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171 views

Are tongues red because they contain blood?

Many animals have red tongues, though not all of them - blue-tongued skinks and giraffes come to mind. Are they red because of the blood (and therefore haemoglobin) in them? It sounds plausible, but ...
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49 views

When was the purpose of bone marrow discovered?

I'm currently reading William Cheselden's book Osteographia or The Anatomy of the Bones, which was published in 1733 (for the pretty pictures, naturally; not up to date anatomy). When he addresses the ...
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47 views

Biological/molecular basis of nutritional need differences between blood types?

There are many nutrition books and websites (like http://www.aqua4balance.com/Healthy-Diet/blood-type-nutrition-educational-workshop.html) that assign very different nutritional needs to individuals ...
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297 views

What is the best color for a PPG signal (photoplethysmography)?

What is the best color for a PPG signal? Red, green, blue or infra-red? I'm asking because commercial oximeter sensors usually use a pair of red and infra-red LEDs. But recently, I've seen a lot of ...
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392 views

Antigen Antibody reactions during blood donation

A person wih blood group O is called a Universal Donor. Well, his plasma contains antibodies A and B. During blood donation, if blood group O is given to a person with blood group A (since blood group ...
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28 views

What Effect would Cannabinoids have on the Acute Porphyrias?

I should be clear in saying that this question is NOT intended for personal medical advice. Rather what I am looking for is journal articles and/or books that touch on this subject because I think it ...
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518 views

What part of food gives the blood red color?

Roughly, what I know is, when we eat food it goes into our: Stomach > Small Intestine > Large Intestine > Rectum. So, it just moves through a digestive pipe. What I don't understand is, what part of ...
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52 views

Why don't individuals with sickle cell trait suffer from sickle cell anemia?

Ostensibly, in people with sickle cell trait, half of the hemoglobin in their body would be defective. Is it actually the case that sickle cell hemoglobin is produced in equal amounts? If not, how ...
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72 views

Is it possible to condition the body to reduce bruising?

I do combat sports, and in these sports there are a lot of hits that can cause bruising. I've found that, over time, physical conditioning can reduce and/or eliminate the bruising to the point where ...
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495 views

Why does blood come from mouth when people are shot in the chest area?

In almost every movie scene when a character is shot in the chest area, some blood comes from his mouth or sometimes even coughs blood before he dies. Are these kind of scenes realistic/possible? If ...
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64 views

Why it is so difficult to treat leukemia?

I want to ask what is the reason that T315I type CML leukemia is currently untreatable. I have read quite a few papers in this subject. Why the current genetic oriented engineering drugs failed to ...
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363 views

Iron deficiency anemia symptoms explanation

In my classes and on the internet, brittle nails and dry hair (or hair loss) are described as symptoms of iron deficiency anemia, but none explains the cause of such symptoms. Does anyone have any ...
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90 views

How is a blood sample analyzed to give the different levels of metabolites?

How is a blood sample analyzed to give the different levels of metabolites? Are there any any procedural differences with each blood test? Thanks in advance!
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716 views

How much does donating blood affect the amount of oxygen in your blood stream at high altitude?

I am a regular blood donor and I am also a skydiver. We normally go to around 13,000 feet AGL (above ground level). Depending on how high above sea level the ground is, altitudes could be as high as ...
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188 views

When giving blood, what is the specific Iron measurement they take?

I went to give blood the other day, and they take an "iron" measurement prior to actually drawing the blood. My level was 16.4 -- but what specific type of iron were they measuring? I've heard of ...
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134 views

How can the child and the mother have different blood types?

As far as I know the fetus is fed by the umbilical cord which basically connects his/her circulatory system with the mother's in order to supply oxygen and nutrients. But how is this possible if they ...
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5k views

Can positive and negative blood type of a couple lead to miscarriage?

I want to know can $+ve$ and $-ve$ blood group of a couple could be a cause of miscarriage in pregnancy?
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51 views

What percentage of human capillaries are located in the skin?

As in the subject line, what percentage of capillaries in a human (expressed in terms of total length, I suppose) are located in the skin, as opposed to internal organs? Google scholar has not turned ...
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43 views

Can gelatine digestion make blood more thick?

Can gelatine cause blood thickening if digested?
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172 views

Does the oxygen concentration equilibrate between red blood cells in the liver sinusoids?

In the sinusoids of the liver, venous blood from the hepatic portal system mixes with arterial blood from the hepatic arteries. Do oxygen molecules move between oxygenated RBCs and non-oxygenated ...
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186 views

What are the clotting factors' effect on avascular necrosis development?

Do clotting factors tpa and pai-1 lead to degenerative osteoarthritis in the same way that lupus anticoagulant and prothrombin might? Is one of these pathways particularly detrimental during formation ...
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Are lymphocyte sizes clustered in two groups?

Tortora writes in Principles of Anatomy and Physiology: Lymphocytes may be as small as 6–9 μm in diameter or as large as 10–14 μm in diameter. Those ranges are quite close to each others. Should ...