The Human Immunodeficiency Virus (HIV) is a single-stranded RNA virus which reproduces in human CD4-positive cells, which are primarily T-helper lymphocytes and macrophages. HIV is the causative pathogen of Acquired Immunodeficiency Syndrome (AIDS).

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Are there people cured of HIV by means of HAART?

I wonder if there people who were cured of HIV only by means of highly active anti retro-viral therapy (HAART) or other drugs rather than by bone marrow transplant? I know that HAART can suppress HIV ...
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Is there a strong reason to be sceptical about the “cured HIV patient” being reported by mainstream media?

There's a story going round the news about a baby that was, apparently, cured of HIV using a cocktail of drugs at an early age. The story piqued my interest, but details seem scarce. One of the main ...
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Why HIV patients have greater virulence of M.tuberculosis?

I am reading Murray Microbiology book. Some facts M. tuberculosis is an intracellular pathogen. At the time of exposure, M. tuberculosis enters the respiratory airways and infectious particles ...
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Reasons why people say that AIDS/HIV doesn't exist

It's been recurrent when I hear people saying that AIDS doesn't exist. When I ask why, they give weird reasons like HIV is a virus created to control economy and to develop medicine, etc. Also when I ...
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Is this a valid principle of curing HIV?

I have a set of questions actually, it will be very helpful if you answer them in order. Where does the HIV virus hide (during incubation period)? Let answer be X cell. Is X cell in the bloodstream? ...
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Can a person be infected with HIV viruses without contacting them by person-related stuffs?

We know that a person can be infected with HIV viruses when he/she has sexual relationship with those having HIV viruses (and very, very, very rarely, urine/defecation-related transmission) - but I ...
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44 views

Which is harder to contract - HIV or AIDS?

I am working on mathematically modeling HIV and Tuberculosis Co-infection dynamics, and am working with 12 differential equations describing the behavior of all of the compartments and parameters. ...
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1answer
27 views

HIV-RT nucleotide contact residues

I'm investigating HIV-RT 3KLF and 1LWF trying to find a perfect pose of thymine. Which residues on HIV-RT is Thymine supposed to contact on 3KLF and 1LWF? Where exactly is the nucleotide binding ...
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qrt-pcr and short fragments

I plan to measure the effects of Tenofovir a Nucleotide analog reverse-transcriptase inhibitors useing qrt-pcr with HIV-RT as the rt enzyme. Tenofovir causes early termination of the reverse ...
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activate a drug using deoxycytidine kinase in vitro

I need to activate a drug similar to the way it is activated in the cell. My set of molecules called Nucleoside analog reverse-transcriptase inhibitors (NARTIs or NRTIs) need three phosphate groups to ...
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in-vitro inhibitor molecule count per reverse transcriptase count

I would like to examine the effects of etravirine in-vitro. How many molecules of Etravirine a HIV Reverse Transcriptase inhibitor are necessary to block a group of Reverse Transcriptase from acting ...
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108 views

HIV and T helper cells

As far as I know and could understand from reading about HIV, T helper cell is one of the main reasons to develop AIDS in patients infected with HIV virus, that because the absence of helper T cell ...
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135 views

HIV Rapid Tests

The hiv antigens that are used in the oral rapid tests, are they infectious? The tests do not contain any actual virus but I am curious if the antigens themselves could somehow create the virus on ...
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Are homozygous carriers of the CCR5-Δ32 allele fully immune to all known strains of HIV?

Or is there documented evidence of even one homozygous carrier contracting HIV and staying infected?
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Can the RNA in the HIV virus make viral enzymes without entering the nucleus?

If the provirus was not formed yet, can the virus make viral enzymes? (I know that it already has some, but supposing it doesn't)
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How does herpes (HSV) infection suppress HIV?

HIV compromises the human body to defend against infection. Yet people who are infected with herpes are at less risk of developing AIDS. How does this work?
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Why human body cannot defend against HIV? [closed]

Some says that HIV destroy IRF3, and some says HIV overruns T-cells.