The Human Immunodeficiency Virus (HIV) is a single-stranded RNA virus which reproduces in human CD4-positive cells, which are primarily T-helper lymphocytes and macrophages. HIV is the causative pathogen of Acquired Immunodeficiency Syndrome (AIDS).

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The ethics of ACST in full blown AIDS patients [closed]

We've always been told that a traditional Allogeneic Stem Cell Transplant (bone marrow transplant) is unsuitable as a treatment option for those living with HIV due to the mortality risks it carries ...
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How Circumcision could reduce the chance for a HIV infection?

Circumcision removes the foreskin of the penis which mainly acts as a cover to the penis. Normally removing the foreskin makes more vulnerable to any STD, so how could circumcision reduce the risk of ...
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Solid phase use in HIV rapid tests [closed]

I have a question in regards to my HIV test research. The rapid tests like Orasures Oraquick contains a strip of synthetic peptides that are used to represent proteins found in the envelope region of ...
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How does a person get AIDS?

I am inquisitive to know about how a person contracts AIDS. Among the common masses it's still the belief that having sex with multiple partners causes the disease but that is not the case when read ...
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Reasons why people say that AIDS/HIV doesn't exist

It's been recurrent when I hear people saying that AIDS doesn't exist. When I ask why, they give weird reasons like HIV is a virus created to control economy and to develop medicine, etc. Also when I ...
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HIV and effectiveness of inhibitor cocktail over single inhibitor

I'm looking for clarification on the answer to this question. It's in my biochemistry class but I figured this is more Biology than Chemistry, so I'm asking it here. The question is: One of the ...
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Why HIV patients have greater virulence of M.tuberculosis?

I am reading Murray Microbiology book. Some facts M. tuberculosis is an intracellular pathogen. At the time of exposure, M. tuberculosis enters the respiratory airways and infectious particles ...
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74 views

It is possible for person with AIDS be negative for HIV antibodies?

I'm just curious as there was a bit controversy around this topic. It is possible for person with AIDS be negative for HIV antibodies? As of 1989, the CDC reported that 5% of all U.S. AIDS patients ...
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Is there a strong reason to be sceptical about the “cured HIV patient” being reported by mainstream media?

There's a story going round the news about a baby that was, apparently, cured of HIV using a cocktail of drugs at an early age. The story piqued my interest, but details seem scarce. One of the main ...
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Is it possible to get infected with HIV from old blood?

Let's say that someone uses a needle which has some old blood infected with HIV. In this case, is it possible for them to get infected with HIV?
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Can HIV be transmitted via breastfeeding?

If a pregnant women is HIV positive and she is treated with medicines to deliver a normal child,can she transfer the HIV virus back to her normal HIV free child by colostrum?
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HIV and T helper cells

As far as I know and could understand from reading about HIV, T helper cell is one of the main reasons to develop AIDS in patients infected with HIV virus, that because the absence of helper T cell ...
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Can a person be infected with HIV viruses without contacting them by person-related stuffs? [duplicate]

We know that a person can be infected with HIV viruses when he/she has sexual relationship with those having HIV viruses (and very, very, very rarely, urine/defecation-related transmission) - but I ...
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Are there people cured of HIV by means of HAART?

I wonder if there people who were cured of HIV only by means of highly active anti retro-viral therapy (HAART) or other drugs rather than by bone marrow transplant? I know that HAART can suppress HIV ...
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Is this a valid principle of curing HIV?

I have a set of questions actually, it will be very helpful if you answer them in order. Where does the HIV virus hide (during incubation period)? Let answer be X cell. Is X cell in the bloodstream? ...
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1answer
59 views

Which is harder to contract - HIV or AIDS?

I am working on mathematically modeling HIV and Tuberculosis Co-infection dynamics, and am working with 12 differential equations describing the behavior of all of the compartments and parameters. ...
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31 views

HIV-RT nucleotide contact residues

I'm investigating HIV-RT 3KLF and 1LWF trying to find a perfect pose of thymine. Which residues on HIV-RT is Thymine supposed to contact on 3KLF and 1LWF? Where exactly is the nucleotide binding ...
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qrt-pcr and short fragments

I plan to measure the effects of Tenofovir a Nucleotide analog reverse-transcriptase inhibitors useing qrt-pcr with HIV-RT as the rt enzyme. Tenofovir causes early termination of the reverse ...
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149 views

HIV Rapid Tests

The hiv antigens that are used in the oral rapid tests, are they infectious? The tests do not contain any actual virus but I am curious if the antigens themselves could somehow create the virus on ...
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Are homozygous carriers of the CCR5-Δ32 allele fully immune to all known strains of HIV?

Or is there documented evidence of even one homozygous carrier contracting HIV and staying infected?
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Can the RNA in the HIV virus make viral enzymes without entering the nucleus?

If the provirus was not formed yet, can the virus make viral enzymes? (I know that it already has some, but supposing it doesn't)
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How does herpes (HSV) infection suppress HIV?

HIV compromises the human body to defend against infection. Yet people who are infected with herpes are at less risk of developing AIDS. How does this work?
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Why human body cannot defend against HIV? [closed]

Some says that HIV destroy IRF3, and some says HIV overruns T-cells.