The Human Immunodeficiency Virus (HIV) is a single-stranded RNA virus which reproduces in human CD4-positive cells, which are primarily T-helper lymphocytes and macrophages. HIV is the causative pathogen of Acquired Immunodeficiency Syndrome (AIDS).

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How does herpes (HSV) infection suppress HIV?

HIV compromises the human body to defend against infection. Yet people who are infected with herpes are at less risk of developing AIDS. How does this work?
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391 views

How does a person get AIDS?

I am inquisitive to know about how a person contracts AIDS. Among the common masses it's still the belief that having sex with multiple partners causes the disease but that is not the case when read ...
11
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120 views

Why do doctors still advise HIV+ couples to wear a condom during sex?

HIV infected people already have HIV, but why do doctors still advise condom use for HIV+ couples?
10
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88 views

Are homozygous carriers of the CCR5-Δ32 allele fully immune to all known strains of HIV?

Or is there documented evidence of even one homozygous carrier contracting HIV and staying infected?
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140 views

How Circumcision could reduce the chance for a HIV infection?

Circumcision removes the foreskin of the penis which mainly acts as a cover to the penis. Normally removing the foreskin makes more vulnerable to any STD, so how could circumcision reduce the risk of ...
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8k views

Reasons why people say that AIDS/HIV doesn't exist

It's been recurrent when I hear people saying that AIDS doesn't exist. When I ask why, they give weird reasons like HIV is a virus created to control economy and to develop medicine, etc. Also when I ...
8
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95 views

Reasons for the HIV-1 epidemic

So, the HIV-1 jump to humans occurred as early as the 1920s, but the AIDS epidemic didn't start until the early 1980s. Some things I don't understand about this: Why the delay? What is needed for a ...
7
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205 views

HIV Rapid Tests

The hiv antigens that are used in the oral rapid tests, are they infectious? The tests do not contain any actual virus but I am curious if the antigens themselves could somehow create the virus on ...
7
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351 views

HIV and effectiveness of inhibitor cocktail over single inhibitor

I'm looking for clarification on the answer to this question. It's in my biochemistry class but I figured this is more Biology than Chemistry, so I'm asking it here. The question is: One of the ...
7
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1answer
299 views

Can HIV be transmitted via breastfeeding?

If a pregnant women is HIV positive and she is treated with medicines to deliver a normal child,can she transfer the HIV virus back to her normal HIV free child by colostrum?
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221 views

What are the effects of removing CD4 receptors?

If the gene for the CD4 receptor was removed, would the person's immune system work normally? Could a new artificial receptor be substituted in place of CD4? Could HIV infection be prevented in this ...
4
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2answers
390 views

Can people with AIDS get tattoos?

When I do a Google search, most of the results are about whether or not people can get HIV / AIDS from getting a tattoo through dirt needles. I am, however, curious whether or not it is possible to ...
4
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3answers
247 views

Are there people cured of HIV by means of HAART?

I wonder if there people who were cured of HIV only by means of highly active anti retro-viral therapy (HAART) or other drugs rather than by bone marrow transplant? I know that HAART can suppress HIV ...
4
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1answer
260 views

Why is an HIV infection considered “incurable”?

My biology teacher told me that if one caught HIV, they cannot be cured because it was near to impossible to be completely virus-free. She said this was because HIV keeps on changing its glycoprotein ...
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121 views

Is there a strong reason to be sceptical about the “cured HIV patient” being reported by mainstream media?

There's a story going round the news about a baby that was, apparently, cured of HIV using a cocktail of drugs at an early age. The story piqued my interest, but details seem scarce. One of the main ...
4
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1answer
41 views

Why does HIV belong to a group of retroviruses called lentiviruses?

HIV is an enveloped retrovirus. Each virus particle contains two copies of an RNA genome. The virus also has a number of enzymes: reverse transcriptase, integrase and viral protease. But, once I also ...
4
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1answer
870 views

Why AZT is selective towards HIV and doesn't impair human DNA replication?

I've found this article, which is a very old one (from the time when nucleoside analogs where researched as a possible way to prevent replication of virus genetic material, before the HIV epidemics). ...
4
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3answers
214 views

HIV and T helper cells

As far as I know and could understand from reading about HIV, T helper cell is one of the main reasons to develop AIDS in patients infected with HIV virus, that because the absence of helper T cell ...
4
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1answer
81 views

Which is harder to contract - HIV or AIDS?

I am working on mathematically modeling HIV and Tuberculosis Co-infection dynamics, and am working with 12 differential equations describing the behavior of all of the compartments and parameters. ...
3
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2answers
123 views

Is there a way to prevent an HIV infection after exposure to HIV infected Blood?

If a person is accidentally injected with blood from an HIV+ person, is there a treatment option that can keep the person from developing an HIV infection?
3
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1answer
550 views

Can the RNA in the HIV virus make viral enzymes without entering the nucleus?

If the provirus was not formed yet, can the virus make viral enzymes? (I know that it already has some, but supposing it doesn't)
3
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117 views

Is it possible to get infected with HIV from old blood?

Let's say that someone uses a needle which has some old blood infected with HIV. In this case, is it possible for them to get infected with HIV?
3
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1answer
56 views

Why is AIDS not a congenital disease?

AIDS can easily pass from mother to the newborn, then why do we not consider it to be a congenital disease (or syndrome)
3
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1answer
36 views

HIV-RT nucleotide contact residues

I'm investigating HIV-RT 3KLF and 1LWF trying to find a perfect pose of thymine. Which residues on HIV-RT is Thymine supposed to contact on 3KLF and 1LWF? Where exactly is the nucleotide binding ...
3
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0answers
28 views

In the life-cycle of the HIV virus, how does the created DNA enter the nuclear membrane?

I am in a high school biology class, so I cannot truly attest to how accurate the information I am given is, but as far as I know only RNA and very small molecules can enter the nuclear membrane ...
3
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222 views

Can HIV mutate to become airborne?

HIV has a very high mutation rate due to its inability to correct errors in DNA replication and it is very adaptable to its environment. Hence I wonder whether is it possible for it to mutate such ...
2
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2answers
169 views

Is this a valid principle of curing HIV?

I have a set of questions actually, it will be very helpful if you answer them in order. Where does the HIV virus hide (during incubation period)? Let answer be X cell. Is X cell in the bloodstream? ...
2
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1answer
281 views

It is possible for person with AIDS be negative for HIV antibodies?

I'm just curious as there was a bit controversy around this topic. It is possible for person with AIDS be negative for HIV antibodies? As of 1989, the CDC reported that 5% of all U.S. AIDS patients ...
2
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3answers
181 views

Why HIV patients have greater virulence of M.tuberculosis?

I am reading Murray Microbiology book. Some facts M. tuberculosis is an intracellular pathogen. At the time of exposure, M. tuberculosis enters the respiratory airways and infectious particles ...
2
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1answer
84 views

How is HIV evolutionarily viable despite its extreme virulence?

How does HIV survive natural selection? And how has it managed to kill far more than any non-airborne virus in recorded history?
2
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0answers
66 views

HIV and open reading frames

In Wilk et al. 2001 I saw that HIV has 3 open reading frames. In the Watts et al. 2009, I noticed they mentioned HIV has 9 open reading frames. I don't understand this very well. e.g. ...
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4answers
260 views

How does HIV mutate into other strains while keeping their virulent phenotype?

How does a virus like HIV mutate into so many strains, and yet all of them are harmful to our immune system? What gives this virus the ability to mutate so efficiently?
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1answer
71 views

Transmission of HIV from Mother-to-Child Through Breastfeeding

If a mother is HIV+ and was on medications which would help her deliver a HIV negative baby, can the baby contract the HIV through her breast milk?
1
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1answer
77 views

qrt-pcr and short fragments

I plan to measure the effects of Tenofovir a Nucleotide analog reverse-transcriptase inhibitors useing qrt-pcr with HIV-RT as the rt enzyme. Tenofovir causes early termination of the reverse ...
1
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1answer
45 views

Engineered CD8 T-cell therapy for HIV infection

CD8 T-cells are effective in controlling HIV during the early phase of the infection. However by the time, the virus mutates and develops an evasion mechanism against CD8 T-cells. Since cancer cells ...
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2answers
999 views

Why human body cannot defend against HIV? [closed]

Some says that HIV destroy IRF3, and some says HIV overruns T-cells.
0
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52 views

Can we use the HIV antibody test to detect HIV in newborns? [closed]

Adults and elder children can use HIV rapid test to test HIV infection. Can we use the HIV antibody test to detect HIV in newborns too?
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Can a person be infected with HIV viruses without contacting them by person-related stuffs? [duplicate]

We know that a person can be infected with HIV viruses when he/she has sexual relationship with those having HIV viruses (and very, very, very rarely, urine/defecation-related transmission) - but I ...