This tag is for questions about the general biological features of human beings (as opposed to the biology of non-humans).

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Counterintuitive action of Vitamin D?

Vitamin D acts in a way which to me is counterintuitive. It functionally supplemets Parathormone. It in the intestinal tract steps up calcium absorption by altering nuclear gene expression and also ...
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169 views

How do the pharmacodynamics of the NSAIDs differ and are there “resistant” COX phenotypes?

I know that the non-steroidal anti-inflammatory drugs (e.g., aspirin, ibuprofen, naproxen) affect the enzymes cyclooxygenase (types I and II). Is there any difference in the degree to which these ...
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38 views

What is the main challenge in creating a chemical male contraceptive?

More than 50 years after hormonal contraception for women was invented, a contraceptive pill for males is still not available. With the obvious major biological differences in mind, why does it appear ...
3
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107 views

Do Asian women have more difficult births than Europeans?

I recently heard a claim that Asians in general have more difficult births than Europeans. Is this true? I have found a few studies(1,2) on the effect of ethnicity on birth outcomes but they seem to ...
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41 views

Database of Medical Assertions

Can anyone point me toward a computationally-accessible database of medical assertions? I'm looking for something where each row in the database contains a single unit of knowledge. It could either be ...
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131 views

Can someone explain the color-changing unit (CCU) to me?

I've been physically carrying out serial tenfold dilutions on samples of Ureaplasma to work out the color-changing units (CCU). As a definition, the CCU is the highest dilution at which there is a ...
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77 views

What are the physiological effects of wine?

I have read that alcohol in general and wine in particular can have advantageous as well as detrimental effects on human health. Is this true? What are the physiological effects of consuming wine in ...
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99 views

What controls the feeling of discomfort/comfort before and after sleep?

I'm interested in which biological systems or hormones are involved in the following phenomenon: Before sleep it may be difficult to find a comfortable position, and muscular aches and pains are more ...
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30 views

Viagra for pain management

Not all men who take Viagra experience any sexual side effects about 40% have no change of sexual abilities on the pill. However like many women the drug in such cases cause a strong pain reduction ...
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93 views

Human female chest model or data representation?

I am looking for professionally used representation of female chest (I know how it sounds ;). Generally - a model comprehensive enough to effectively represent human chest, with focus on breasts. ...
2
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77 views

How is color information transmitted from eye to brain?

Is it frequency-modualated or are different colors transmitted by different axons? I know that each ganglion cell is connected to multiple photoreceptors. How does it tell the brain which ...
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43 views

How well do we notice asynchronicity?

I'm stopped at a stoplight and, with nothing to do, my thoughts wander to the timed don't-walk sign that governs any pedestrians who might wish to cross the street I'm driving along. I can see two ...
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62 views

Are simple esters like those used as flavouring agents metabolised into their constituent carboxylic acids and alcohols in the human body?

By this I mean to ask whether say ethyl butanoate is hydrolysed in humans into ethanol and butyric (butanoic) acid. This is of interest to me as a pharmacology researcher because butyric acid, for ...
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43 views

Why do fresh cavities form from the margins of sliver amalgam fillings on teeth?

Silver amalgam fillings predominantly contain silver a known bactericidal agent and mercury which a known toxin and has bactericidal property. So how is it that the plaque bacteria survive near the ...
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117 views

What tests can be performed to test the purity and quality of the raw peptide HCG (Human Chorionic Gonadotropin)

What tests could be run to test the purity and type of HCG? We are looking to purchase HCG from China but the purity and quality varies between labs, we are able to receive samples of the raw peptide ...
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55 views

Movement of stem cells from mother to fetus

Recent results from J Lee Nelson and colleagues (Sci Am. 2008 Feb;298(2):64-71; available as full text through Google) show that cells from the mother were found in a person aged 46. Logically, these ...
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46 views

How to use mechanical microstrainer to extract tissue proteins from human?

Background: There are many methods to extract proteins form human tissues out there. The majority of them use an extraction buffer containing variable concentrations of detergents and protease ...
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35 views

What processes are responsible for focusing on an image only seen by one of the eyes?

When a person is spying from around a corner with only one eye, it's rather easy to ignore the other eye's image, since it's probably much darker, because one usually spies around a corner standing ...
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77 views

How do omega-3 fatty acids reduce cholesterol at the molecular level?

I have heard that omega-3 fatty acids found in fish are a good way to prevent/reduce cholesterol problems. My question is how do omega-3 fatty acids do that: what are they doing on a chemical level ...
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37 views

Is there an entry-level circadian model of serotonin, ghrelin, dopamine and the sense of well being?

I've long been interested in circadian rhythms and recently came across a variety of articles that appear to indicate that the following neurotransmitters, transferases and hormones are connected. ...
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50 views

Do humans have chemosensors for nutrients or chemicals?

I'm reading about chemoreceptors on Wikipedia, and see that the typical ones are mentioned: taste, smell, co2. I would like to learn more about the other kinds of chemoreceptors that humans may ...
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137 views

Virucides - Herbal and otherwise, for HHV6 type virus or any inner-cell virus

Does anyone know where I can find a reliable list of virucides (not anti-virus) that can be used by humans? This virucide must be able to affect viruses that are already inside the cells. St John's ...
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243 views

Can the sleep/wake cycle be influenced by non-visible spectrum electro-magnetic radiation?

I've been reading a few papers on Melanopsin and Suprachiasmatic Nucleus (SCN), and see that the sleep/wake transition is ...
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62 views

Are there any situations in which phenylephrine is preferred to pseudoephedrine?

In the mid 2000s in the US, due to issues of drug enforcement, pseudoephedrine containing medications were brought behind the pharmacy counter and in most cases require ID, and phenylephrine was ...
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23 views

Is there a difference between endorphins that are released while physical activity and sex/masturbation?

I observerd myself and I can identify two different types of "happines". First - called by me - After Pleasure : Occurs AFTER (and last long) long activity that require from me engagement focus and ...
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73 views

In-Ear headphones increasing nasal breathing resistance

I figure this is a rather strange question, however, I noticed this quite some time ago and wanted to make sure that this is in fact a permanent condition before posting. The situation is as follows: ...
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42 views

Relationship between small and large fast-twitch motor units

When large fast-twitch motor units are temporarily fatigued, non-fatigue small motor units in the same muscle are impaired for small delicate tasks. Why? When impulses from the brain comes down, the ...
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28 views

Nearly Exhaustive List for Cholesterol Pathways

I have run across an interesting case that is similar to only two others I've encountered. What makes it interesting is the combination of undetectable (under normal testing conditions, can elaborate ...
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34 views

How can one accurately diagnose human hearing loss without surgery?

In a human, if you were to avoid a tympanotomy, how could you distinguish between a blocked Eustachian Tube, a ruptured eardrum, or Perilymph Fistula? For instance take the situation where a young ...
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22 views

Is there a homeostatic setpoint for number of hours of sleep required by a human?

I've heard this TED.com talk about dieting and it mentions that there's a very definitive setpoint within the human brain about how much a human should weight. The speaker mentions that after as much ...
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141 views

Why are people tired after surgery?

I had surgery when woke up I felt like I only had 20% energy & felt extremely tired. Is this a common sensation? Why do people feel so tired after surgery?
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39 views

Why does the ovum prefers to be arrested at metaphase 2 of meosis before fertilization? What is the possible advantage of this process?

Why does the human ovum prefers to be arrested at metaphase 2 of meosis before fertilization? What is the possible advantage of this process??Please help me with it.
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69 views

Sodium levels and blood pressure

Why does low $\ce{Na+}$ levels cause hypotension (low blood pressure). Alternatively, why does excessive intake of $\ce{Na+}$ cause hypertension or high blood pressure? From what I ...
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55 views

Possible long term side effects of IV iodine contrast

There are some illnesses that are linked with Iodine deficiency, most notably Multiple Sclerosis (MS) and Parkinson's. The resulting correlations suggest that mortality from Parkinsonism, ...
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40 views

What parts of the brain are involved in regulating blood pressure in mammals?

I'm reading this Wikipedia article on blood pressure and its regulation, and it mentions that medulla is involved. however, I vaguely remember reading another article on Wikipedia and it mentioned ...
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222 views

Size order of human organs

Wikipedia states that the liver is the largest internal organ in the human body. How does it relate to the sizes of ex. the lungs and small intestines? I've been having this personal image for years ...
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78 views

Why do ion concentrations change with different secretion rates in pancreatic juice?

Why is it that when secretory rate increases in the pancreas the concentration of chloride ions decreases, and the concentration of bicarbonate increases in the production of isotonic NaCl secretion? ...
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107 views

How does geography affect morphological features of the human body

I've seen many times how a person born in one place, goes to another country for a long time, and then they start looking more like the people there, but I never found out how it works. This report ...
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138 views

Are there nutritional benefits to drinking diluted urine?

I know that urine drinking is a widespread practice (with a long history). The main reason that people give today involves there being nutrients in urine. If there are nutrients to be gained, why is ...
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30 views

Are anti-inflammatories useful for tendinosis?

I am wondering why some doctors prescribe anti-inflammatory treatments for conditions that are supposedly not inflammatory such as tendinosis. From my understanding, only tendinitis a swollen tendon ...
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76 views

Why do people feel extreme cold at different temperatures compared to other people of same body structure?

I have seen some people shivering in the room temperature of 18°C while others of similar body structure do not feel that much amount of cold. Of course the clothing of both people is similar if ...
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16 views

What are studies linking dietary choices over life with probability of reaching higher ages?

Are there big studies that link diet and lifestyle choices with the probability of reaching a certain age? What are their conclusions?
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116 views

Can dry air make a person more prone to catching a cold?

I'm interested if there is a correlation between room air humidity and risk of catching a cold.
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50 views

Does Dorsal Raphe Nuclei firing pattern change in response to voluntary breathing?

I'm reading this paper, which discusses how Serotonin may be involved in motor functions of mammals: 5-HT and motor control: a hypothesis . The paper includes the following diagram of the Dorsal ...
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37 views

Can we make any judgements about sleep or readiness to sleep from a heart rate metric and/or pulse oxymetry?

I'm looking at inexpensive and un-intrusive ways to quantify the state of human body/mind . One of these is Actigraphy, which is a study of human motion over time. This can be done with an iPhone ...
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32 views

Can progerin formation be triggered explicitly?

Corollary to my question - Could inhibition of progerin formation slow the rate at which a body ages? Is it possible to activate/trigger progerin formation explicitly? Say, by some hormonal/chemical ...
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54 views

Are the intestinal flora substantially different within a diverticulum of the colon?

From the Wikipedia page for the vermiform appendix: This proposal is based on a new understanding of how the immune system supports the growth of beneficial intestinal bacteria, in combination ...
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9 views

What triggers the release of gonadotrophin-releasing hormone with the onset of puberty?

I am interested to know the process of development of puberty. During puberty, when boys/girls reache 12-14 (puberty) years of their age, their hypothalamus releases gonadotropin releasing hormone ...
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16 views

Any relevant knowledge/studies about voluntary goose bumps

I'm not entirely sure how normal this is, but since I was a child, I've been able to produce myself voluntarily a "chill" sensation that seems to start on my head and traverse the rest of my body, ...
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53 views

Why the scent of mouth gets dirty after not eating for a long time?

After a long time of hard workout,not eating and nervousness makes your taste and scent of mouth very uncomfortable and bad why this happens and is there any way to prevent it?