0
votes
1answer
15 views

Cell targets of Glybera

So we know that there is a first gene therapy drug in the market out there called Alipogene tiparvovec to address lipoprotein lipase deficiency (LPLD) at a genetic level. Does this genetic drug ...
0
votes
0answers
18 views

How loss of heterozygosity influence expression levels of a gene ?

I am looking at a genomic region associated with a vascular diseases; this region have loss of heterozygosity. I am wondering how the expression level of the genes in the regions will be affected ...
1
vote
1answer
61 views

Studying genetics [closed]

I am interested in studying disorders that are genetic in origin. However, I am having difficulty in understanding molecular and cellular mechanisms regarding processes such as meiosis, mitosis, and ...
2
votes
1answer
48 views

PGC-1β Sod2 limiters/blockers

I'd like to block a percentage of PGC-1β or Sod2 expression. According to the following paper's figure beta-blockers inhibit some expression of PGC-1α. Are there any medicines/chemicals which safely ...
4
votes
1answer
814 views

Is ovum + ovum fertilization possible for human?

In humans is it possible to fertilize a ovum with another ovum from the same female subject? I already found some works in which the ovum is fertilized by a somatic cell (see e.g. this ), but I am ...