The scientific study of inheritance as it occurs specifically in human beings.

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Is the DNA different in each type of cell? What DNA is passed to offspring?

Our body contains many different types of cells and each of those cells have their own DNA (correct me if wrong) like skin cells their own DNA that makes them skin cells instead of muscle cells. So ...
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0answers
16 views

How should one interpret heritability? Is it related to $R^2$?

From Wiki: Heritability estimates are often misinterpreted if it is not understood that they refer to the proportion of variation between individuals on a trait that is due to genetic factors. It ...
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3answers
9k views

Is it possible for a child to grow taller than their tallest parent?

I have heard that offspring can't grow taller than either of their parents but I've also heard that sometimes some gene activation can skip generations. Is it possible for a child to grow taller than ...
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0answers
11 views

I am 15 and 163 cm tall - will I grow taller? [migrated]

I am a 15 year old Indian. I currently stand at 163 cms but I weigh 75 kg, which is overweight I know. But is there any way I'll grow more? If yes, how much? My dad's height is 172 cm and my mom is ...
2
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3answers
158 views

Swapping genes?

So, gene therapy is to take out a gene, correct its mutation, and put the corrected one back into the organism, right? Is it also possible to take out a gene from an organism and put in a totally ...
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1answer
23 views

“Heterozygotic expection” - when heterozygote differs from both homozygotes, but homozygotes are similar

For simple 2-alleles genetic model {a,A} and corresponding quantitative trait Q is typically true that Q(aa)>=Q(aA)>=Q(AA) or conversely Q(AA)>=Q(aA)>=Q(aA). For example, dominance means that ...
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1answer
110 views

What percentage of people today would likely be descendants a man born 4,000 years ago?

Assuming a particular man was born in southern Mesopotamia, around 4,000 years ago, and was significant involved in a major religion. To what degree (if any) of accuracy could his descendants be ...
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0answers
30 views

How much genetic divergence must there be to yield two different species? [duplicate]

I read that humans are a few percent Neanderthal. So how much difference between egg and sperm is needed for there to be no offspring. That is, for there to be two different species? Is this a ...
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1answer
136 views

Why are the genomes of Humans 99.5% the same?

Human's DNA sequence is said to be roughly 99.5% equal. As far as I understand, this means that if I walked up to you and compared our DNA, the sequence of base pairs would be 99.5% the same. My ...
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1answer
89 views

Have there been any “chopstick gene” mistakes in genetics? [closed]

I've heard of the "chopstick gene" fallacy - wrongly assuming an association between genetics and some characteristic, confounded by non-genetic factors. Has this fallacy happened in real life? I'm ...
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5answers
9k views

Do humans have enough biological differences to be grouped into races or subspecies?

After my online research on the subject, I learnt that, biologically speaking, many scientists believe that there is no such thing as a race. Homo sapiens as a species is only 200,000 years old, which ...
5
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1answer
278 views

How does a fetus retain a blood group different from its mother?

It's a well-established fact that blood group is decided by genotype. But, when a new child starts its journey in the womb, the mother's blood (along with it's agglutinins and agglutinogens) flows ...
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0answers
15 views

What would the resulting karyotype be if someone with Klinefelter syndrome fertilized an “empty” egg?

Endoreduplication: is a form of nuclear polyploidization that results in multiple, uniform copies of chromosomes. This process is common in plants and animals, especially in tissues with high ...
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2answers
2k views

The Uniqueness of DNA Paradox

How can everyone have unique iris and fingerprints? After a certain amount of human beings have lived on earth, wouldn't it be possible to exhaust all possible combinations? The same principle ...
3
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2answers
46 views

Is there a realistic “family tree” model for the human population?

I would like to do some gene inheritance simulations, and I was wondering if there is an accepted model for what mating looks like in the general human population? I am not necessarily looking for the ...
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2answers
53 views

Prader-Willi Syndrome and Angelman Syndrome?

On the website http://www.whatisepigenetics.com/fundamentals/2/ it states that the imprint disorders Prader-Willi syndrome and Angelman syndrome, display an abnormal phenotype as a result of the ...
0
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0answers
31 views

Is it possible to have raw ngs data to practice

I'm looking for raw human ngs data to practice in bioinformatics. Better if it is from different machines (illumina, roche, pacsbio, etc). Panels, exomes and genomes. Anyone knows something?
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2answers
12k views

Why do we assume that the first humans were dark-skinned?

According to the article Dark skin and blue eyes: How Europeans once looked: It is widely accepted that Man's oldest common forefather was dark skinned, and that people became more pale as they ...
0
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1answer
117 views

What does it mean to have a Y-DNA Haplogroup “R-M512”? [closed]

I did a DNA test to learn about my origins, but the results are highly technical. I see I have a Y-DNA Haplogroup R-M512 and a mutation (zero marker in DYS448). I Googled these terms and came across ...
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0answers
12 views

heterolog bodysites development?

Would it actually be possible due to unhomogen distribution of growth factors in the growth of an embryo to develop conditions like Polydactyly only on one side of the body or in an even stranger ...
6
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1answer
650 views

Why is there no cure for Dandruff?

It looks like a simple problem, affecting almost half of the population at the post-pubertal age and of any gender and ethnicity [wikipedia]. What is so complex about finding a cure? Also, if you know ...
2
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1answer
59 views

What does it mean to clone a gene?

When I look up information related to the identification of disease genes, texts will often refer to the gene being "first cloned." What does "clone" mean in this context? Is it simply a synonym for ...
2
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1answer
24 views

Inheritance patterns in individuals with triploidy

If you search on the genetics of Down's Syndrome, you'll find plenty of results explaining the genetic mechanisms which can result in triploidy. However, I can't find any information on the ...
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0answers
46 views

How to find name of the gene

Considering the kegg page, this page contains the description of the gene Edwardsiella tarda EIB202: ETAE_0074 . Now this gene has a name given in the page as : wabG. Now considering another gene 1 ...
4
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1answer
45 views

Human Endogenous Retroviruses

I am reading this paper, which shows that a Human Endogenous Retrovirus (HERV) K provirus is present at the orthologous position of gorilla and chimpanzee genomes but absent in the human genome. If ...
0
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1answer
88 views

difference in genetic instuctions between male and female [duplicate]

I'm a computer science graduate so please bear with me the following computer program : mov ecx, -1 INC ecx consist of 2 instructions (mov,inc) each working on specific data , can genetics ...
2
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2answers
43 views

Do eukaryote cells contain DNA that isn't part of a chromosome or located in the mitochondria?

I specify eukaryote in the title, but I'm also interested if this question isn't applicable to eukaryote cells in general but is to humans. I was reading "RNA-seq: An assessment of technical ...
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2answers
54 views

When did human ancestors learn to walk? [closed]

Where does our ancestor learn to walk from? How do we control our legs whenever we take a step? I confuse every time whenever I take one step.
5
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1answer
95 views

Where in the world does blue eyed whites originate from?

I know that there were no blue eyed people until ~6000 years ago due to a mutation and all blue eyed people have a single common anchestor. But where in the world does it originate? I assume it ...
8
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1answer
103 views

Horizontal gene transfer from humans

It is known that some viruses embed themselves in the human genome. Is there a mechanism by which human genes can be transferred to other animals or plants by means of viruses shuttling them from ...
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0answers
13 views

Serotonin activity with short 5-HTT promotor region and depression

So after reading a few studies (1,2) it seems that a shorter promotor region for the serotonin transport protein may be associated with increased likelihood of developing depression after stressful ...
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0answers
91 views

Why do my 23andme results only show me as 8.2% Scandinavian? [closed]

I just got my 23andme results back. My paternal grandfather was full Swedish. Shouldn't that make me 25% Swedish? 23andme tells me I'm only 8.2% Scandinavian. Or maybe my father inherited less than ...
3
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0answers
48 views

In what way is ADHD genetic? [closed]

According to Psychcentral depression, bipolar disorder, ADHD, schizophrenia and autism are traceable to the same inherited genetic variations According to AsapSCIENCE, depression could be genetic due ...
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0answers
28 views

Will someone with a double mutation in the allosomes be normal?

Normally a female human has an X allosome from her father and an X allosome form her mother. What if an double mutation happened, which causes that someone has two X allosomes form her mother and no ...
0
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2answers
107 views

how do I find the number of bp in chromosome 3 by knowing number of bp in chromosome 1?

If i have a number of bp in chromosome 1 for example(298,295,559 bp) can I use this number to find the number of bp in chromosome 3.
10
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2answers
2k views

Why did humans lose their fur?

The little amount of body hair humans have don't seem to be of much use for keeping warm. Our Simian cousins on the other hand sport thick furs. At which point during the species evolution and why ...
0
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1answer
29 views

IBD-value and IBD-fraction

I have some questions about the IBD-value and IBD-fraction for two of the condensed identity states, $S_1$ and $S_7$. My questions: 1) Is the IBD-value for the individuals i and j two (2) in $S_1$ ...
3
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2answers
95 views

Do transposons usually jump from one chromosome to another?

If it is usual occurrence, does it mean that my one gene can change its location from one chromosome to another?
3
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1answer
36 views

Genetics of epilepsy

Is epilepsy genetically inheritable? If yes, is it dominant?
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0answers
20 views

Genetic component to the location of acquired nevi (moles) on humans?

One of my sons, currently age 4, who was (as is typical) born without moles, has begun to develop them (as is also typical). I noticed that his largest mole is in practically the exact same location ...
5
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1answer
307 views

Why do men grow facial hair?

Ancestral facial hair. Our closest ancestors, the chimpanzee and bonobo, both grow facial hair around the mouth area. What is noteworthy is that this is the case in both males and females of the ...
2
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1answer
15 views

How and why are cells irradiated in human-rodent hybrid cell biology?

When human-rodent hybrids are made the amount of human chromosome in the hybrid can be reduced by irradiation. Why and how exactly is this irradiation step performed?
0
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1answer
149 views

why didn't natives of south america evolve darker skin?

I understand that darker skin tone is caused by melanin which helps to protect against the extra UV radiation that comes from more direct sunlight. It evolved in Africa before we migrated away from ...
5
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2answers
83 views

How can a chromosome translocation in somatic cells lead to disease?

Looking at this picture... ...I get the impression that the part of chromosome is attached to other chromosome, but it is not mutated. When we assume that all genes in the translocated part are ...
9
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2answers
137 views

Cause of hexadactylisim in Amish people

Is it caused by inbreeding of many generations within an isolated population?
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1answer
86 views

Is each generation getting older? [duplicate]

So we know that our sperm and egg cells get set aside relatively early so that they aren't going through unnecessary cell divisions and causing DNA damage or telomere shortening, but since each new ...
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3answers
138 views

Sense and anti sense strand

Why the sense strand is only involved in transcription though the antisense strand just has the compliment strand of the sense strand?
2
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1answer
36 views

DNA dependent RNA polymerase

How does a RNAP locate a specific gene? For instance, growth hormone has to be produced and the RNAP has to locate the gene. But the promoter (TATA box) will also be present infront of all cistrons. ...
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2answers
72 views

Referencing the homologous chromosomes

There exist a co-ordinate system from chromosomes like "12p11.3". In this system, first integer range from 1 to 23 i.e it takes homologous chromosomes as a pair. If we want to distinguish among ...
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1answer
35 views

MTHFR recessive alleles and B-vitamins

I know that being heterozygous or homozygous recessive for the MTHFR gene prevents that person from being able to process and use folate and B-12. It causes an unhealthy level of homocysteine to ...