The scientific study of inheritance as it occurs specifically in human beings.

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How come most animals never seem to evolve over millenia?

People often say, including those with extensive knowledge in biology, that a certain species of animal will evolve in one way or another: 1.From changing environments. 2.Mutations. 3.Possibly even ...
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2answers
520 views

Initial population when i count backwards?

My question is dealing with how many ancestors it took to produce me: --> to produce me it took 2 people (my parents) = ($2^1$) people = 2 --> one generation further included = ($2^1 + 2^2$) people ...
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1answer
463 views

Like other animals, why humans don't have species & breeds?

Like other animals, why don't humans have species & breeds ? Even my pet dog is one type of breed, but we (humans) lack breeds & species? What is the main reason?
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1answer
460 views

What hair color will result in someone inheriting both blond and ginger genes?

Both the genes for blond hair and ginger hair are recessive, so they need both parents to give the same gene for it to take affect. What happens when a person has 1 copy of a recessive gene and ...
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3answers
727 views

What is the difference between eugenics and evolution by natural selection?

So with the working definition of Eugenics: "the aim to improve the human gene pool". What are key features that distinguish Eugenics from evolution by natural selection? I mean, besides that natural ...
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1answer
138 views

What is the evolutionary cause for various finger lengths?

Why are the lengths the way they are with middle finger the longest?
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1answer
43 views

How to determine genotype?

In humans, the ability or inability to roll the tongue is a single gene trait. The allele for tongue rolling (R) is dominant to the allele for not being able to roll the tongue (r). Whether ...
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2answers
61 views

Can genetically engineering the DNA of a human zygote, make it a twin of another human in entirety?

My question is simple. If I wanted to make an exact twin of an individual, will genetically engineering the DNA of the zygote to match with the individual suffice?
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2answers
228 views

How does Humira work when injected into patients with rheumatoid arthritis?

OK, I have rheumatoid arthritis and I've been injecting Humira 2 times a month for the last 8 months. As far as I know rheumatoid arthritis is simply an immune system disorder which makes the immune ...
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1answer
60 views

Why do haemophillic females $X^hX^h$ die before birth?

I just came across a statement in my book , while reading genetics, that haemophiliac females do not survive till birth (the reason not mentioned here why) . Before posting this question here I ...
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1answer
29 views

Is there a realistic “family tree” model for the human population?

I would like to do some gene inheritance simulations, and I was wondering if there is an accepted model for what mating looks like in the general human population? I am not necessarily looking for the ...
3
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1answer
352 views

What factors govern the variable age of onset in Huntington's Disease?

"Huntington's disease (HD) is a neurodegenerative genetic disorder that affects muscle coordination and leads to cognitive decline and psychiatric problems." As we all know, this genetic disease ...
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1answer
90 views

Predictable microchimerism

I read in New Scientist recently that microchimerism occurs between previously born siblings and grandparents, not just the mother. Do we know which parts of the genome are likely to be transferred? ...
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1answer
33 views

Forensic genetics- why is mtDNA comparison sometimes better than nDNA comparison?

Why is (in forensic genetics) in some cases more appropriate comparison of nuclear DNA but in some other cases comparison of mitochondrial DNA? Is it because geneticists are sometimes unable to find ...
3
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1answer
87 views

Regeneration capabilities in humans?

To what extent can humans, (mammals in general), theoretically regenerate, and is their a way to speed up and/or exceed this original extent.
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0answers
40 views

Y Chromosome in Ovary Cancer Data

I have been analyzing TCGA Ovary Cancer data. In Somatic Mutation data, there is data of mutations in all the chromosomes (1-22 and X), but amazingly, I have found one (just one) row of Y Chromosome ...
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63 views

Current Trend in Evolution of Human Intelligence

Up front, I am specifically not interested in philosophical or ethical considerations re Eugenics and related concepts. In an effort to receive a concise answer I'll post a narrowly defined question ...
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6answers
132 views

Which information can be obtained from a list of gene names?

Lets say I only have a list of gene names. I know they are up regulated and I know they are related to cancer. What information can I obtain from having only the names of genes? For example is there ...
2
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1answer
182 views

Is it really detrimental to humans as a species to reproduce with one's own first cousin?

Tired of hearing of these urban legends and popular opinions, I ask this question here to see if there really is scientific merit to this belief. My questions is, is it really "harmful" for a person ...
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2answers
902 views

Are human males and females more genetically different than members of other species?

I'm looking at this Ted talk about a Saudi Arabia woman who dared to drive a car in the last few years. This reminds me that until the last century or so, women (all over the world?) enjoyed less ...
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1answer
31 views

Skin color explanation?

I do not understand how skin color in humans work, even after taking a basic genetics course and reading some on wikipedia. From what I understand, skin is color based on multiple genes that control ...
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1answer
280 views

Is tongue rolling genetic?

Is the ability to roll your tongue or not truly inherited or genetic? What I have gathered from school has been contradicting with evidence I found elsewhere.
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1answer
57 views

Markers for human genetic mapping

For human genetic mapping several different types of markers are used: RFLPs (Restriction Fragment Length Polymorphisms) VNTRs (Variable Number of Tandem Repeats) such as mini- and microsatellites ...
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1answer
35 views

Will a vasectomy prevent genetic engineering of a child?

Making the assumption: Within 10 years, an adult will be able to genetically engineer (modify, enhance, clean, etc.) a child from their own DNA (and the DNA of a non-related partner). then would ...
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1answer
674 views

What do rs id, allele coded 0 and allele coded 1 mean?

So, for a project I've been working on (different story), I've been looking at the HapMap Project, and their free online files. In their README file, they talk about how for each legend file for each ...
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1answer
144 views

Why do genitals feel frozen when freefalling?

I don't want to add much more about that. Since childhood I noticed a chilling effect, even when doing rollercoaster-type activities.
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2answers
40 views

Recessiveness of allele for protection of organism

Heterozygous organisms profit from pairs of gene alleles. Harmful alleles when being recessive can be carried without any harm for the organism. Only when two harmful recessive alleles form a gene the ...
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1answer
1k views

Why do humans seem so much more prone to disease than animals? [closed]

It seems like when we observe animals in the wild, the occurrence of noticeable disease in adult individuals is much lower than in humans. Why? There are a number of reasons that this could happen, ...
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1answer
211 views

List of heritability estimates in humans?

Many people on this site ask questions that directly or indirectly have to do with heritability in human. Do you know a list of estimates of heritability of various traits in humans? Or could you try ...
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1answer
262 views

How do PLINK files and HapMap Phased files differ?

I know that PLINK and HapMap files show the same information, but can you give a thorough explanation of how exactly they differ.
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1answer
21 views

Confused with gamete sorting problem

A man has the genotype AaBbCc, in other words he is heterozygous in three uncoupled loci on three different chromosomes. A, B and C are the dominant alleles while a, b and c are the recessive alleles. ...
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1answer
22 views

MTHFR recessive alleles and B-vitamins

I know that being heterozygous or homozygous recessive for the MTHFR gene prevents that person from being able to process and use folate and B-12. It causes an unhealthy level of homocysteine to ...
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1answer
96 views

Have there been any experiments that duplicate chromosome copies from 23*2 to 23*3 or 23*4?

Deinococcus radiodurans is an amazing bacterium with a fantastic survival rate. It can survive to high doses of radiation, in a complete vacuum and in hydrochloric acid. How does this bacterium ...
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0answers
62 views

Can DNA test of my grandparent's brother reveal my heritage from that branch of the family?

I'm thinking about doing that DNA test on all my grandparents to know where their genes come from. They are getting very old and I don't want to let the opportunity pass to gather more knowledge about ...
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2answers
87 views

Swapping genes?

So, gene therapy is to take out a gene, correct its mutation, and put the corrected one back into the organism, right? Is it also possible to take out a gene from an organism and put in a totally ...
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0answers
53 views

Are the Chromosomes organized in any meaningful way? [closed]

So my major is in pharmacy but both my master and my (currently in progress) doctoral degree are both in theoretical chemistry. My thesis is about quantum chemistry and proteins, but it has a certain ...
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0answers
57 views

Can a heterozygous allele show non-heterozygous expression in a family?

I'm doing a family study looking for novel cancer-associated variants in germ-line samples; the goal is to find candidate biomarkers which might be used for early detection. At an earlier step our ...
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1answer
52 views

PGC-1β Sod2 limiters/blockers

I'd like to block a percentage of PGC-1β or Sod2 expression. According to the following paper's figure beta-blockers inhibit some expression of PGC-1α. Are there any medicines/chemicals which safely ...
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2answers
123 views

Would it be correct to state that any biological difference between the sexes has to be found in the Y chromosome?

If the reason Why Men Don't Listen and Women Can't Read Maps is genetic, then one of the genes in the Y chromosome is to blame and in theory could be identified. Correct or incorrect?
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If a gene is located on the X sex chromosome does that mean males are either Homozygous dominant or Homozygous recessive and are never Heterozygous?

As said in the title I am a little confused on the Idea of traits located on the sex chromosomes. The example we worked on in class was hemophilia a recessive trait and since it is located on the X ...
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1answer
96 views

Generating custom human DNA sequences based on traits such as eye colour?

I'm wondering if it would be possible to create software (unless some already exists, but I couldn't find any) to generate human DNA (the base pairs on the double helix) containing genes representing ...
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3answers
41 views

How do scientists decide which version of a polymorphism is the main one?

This in fact has bugged me for years, but now I finally remembered to ask. I suppose that if one variation is more frequent, it can be labeled as the default, but what about variations that are ...
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2answers
128 views

Which was the last significant event in human evolution? What's next?

At 10.000 BC (12 ka), we became the last of the Homo species on Earth. In evolutionary terms this is a very little time range to something happen, but I'm wondering anyway, in this meantime which are ...
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1answer
25 views

Y-chromosome and phenotype

I have a male colleague which has a son that does not resemble its father in any degree (apart of being male). The "father" is thin, tan-skinned, brown-eyed and the "son" has blue eyes, blond and ...
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1answer
75 views

Are there any studies of epigenetic difference between twins during their lifespan?

Are there any studies of epigenetic difference between twins during their lifespan ? I ask because I wonder if there exist phases during lifespan, when environmental factors plays major role ...
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1answer
225 views

Is there any measure by which the Germans today could be called a genetically superior race? [closed]

The Nazi eugenics programs are well known. Despite their controversy, I cannot find any indication on their effectiveness. Were there ever and studies done on the (arguably subjective definition of) ...
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2answers
403 views

How many recombination events are there per generation in humans?

I'm looking for a reference that tells me how many recombenation events occur in humans from one generation to the next. Assuming that the human genome is a 3.3 GigaBases long DNA sequence, how many ...
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1answer
74 views

Religion and Genetics

Are there studies that investigate the heritability of believing in supernatural things (or related concepts)? Or stated differently. Are there studies that ...
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2answers
184 views

Hardy-Weinberg Equilibrium: To compute probability of finding two siblings (random mating)

I've been working a little with M. G. Bulmer's Principles of Statistics (Dover, 1979) and cannot see how to properly compute half of one question. This should be a basic probability computation, but I ...
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3answers
65 views

DIY storing family DNAs' samples for future uses (eg medical)

I have a question I could not get an understandable reply from Google and I am no expert in the matter, so my plead to you is if you could give me practical and relatively easy to follow advice. With ...