The scientific study of inheritance as it occurs specifically in human beings.

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What effect does the Barr body have, in relation to female Turner syndrome?

Why do persons with Turner syndrome have developmental abnormalities, when normal XX-females do not, even though they only have 1 active X chromosome? From what I know, one X-chromosome is ...
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514 views

Can humans shorten their sleeping patterns?

Can sleeping patterns be trained, or are they genetic? I read that a human needs to sleep at least 4 hours. Can sleeping time be reduced without having a negative impact?
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Is the DNA different in each type of cell? What DNA is passed to offspring?

Our body contains many different types of cells and each of those cells have their own DNA (correct me if wrong) like skin cells their own DNA that makes them skin cells instead of muscle cells. So ...
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A colony of humans are sent to an alien world, at what point would the descendants evolve to be genetically incompatible with Earth humans? [closed]

I recently heard about the evolution of the London Underground mosquitoes, and how they have changed genetically enough that they almost can no longer reproduce with above ground mosquitos. Since this ...
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Why are irises unique?

I heard that irises are different and unique for every person. According this link, probability of two irises having identical pattern is 1 in 10 to the 78th power. That's how iris scanners identify ...
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646 views

Would a spinal injury decrease human height?

A woman I know has been losing height at a rate of few cm a year following a severe spinal injury. How is this possible? What kind of injury could cause such progressive loss of height? Could this be ...
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217 views

Is there some genetic variance underlying music appreciation?

Is there any research done on the genetic variance for Music appreciation? If not, why is there no genetic variance for this trait?
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Is ovum + ovum fertilization possible for human?

In humans is it possible to fertilize a ovum with another ovum from the same female subject? I already found some works in which the ovum is fertilized by a somatic cell (see e.g. this ), but I am ...
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102 views

Proving time travel

Consider this answer to an interesting question. It's not possible to prove completely that someone is the descendant of someone else, there's always a nonzero probability that the results are a ...
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459 views

Redheads and pain receptors

I remember reading this in a biology textbook, and decided to do a little digging. Redheads have a lower sensitivity to some pain and a higher sensitivity to other compared to people of other colored ...
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67 views

Basic Genotyping

As a disclaimer, I'm from a computer science / statistics background, working on some bioinformatics problems. I've got some genotyping data (VCF from Exome Sequencing), and I'm struggling to get my ...
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50 views

Human Endogenous Retroviruses

I am reading this paper, which shows that a Human Endogenous Retrovirus (HERV) K provirus is present at the orthologous position of gorilla and chimpanzee genomes but absent in the human genome. If ...
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278 views

Why isn't Rh disease present in other mammals?

I have read about Rhesus D Hemolytic Disease of the Newborn, sometimes called "Rh disease". It's rare, but it can happen when an Rh+ baby is conceived by an Rh- mother. This raises many questions. I ...
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Y Chromosome in Ovary Cancer Data

I have been analyzing TCGA Ovary Cancer data. In Somatic Mutation data, there is data of mutations in all the chromosomes (1-22 and X), but amazingly, I have found one (just one) row of Y Chromosome ...
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232 views

Is better healthcare a bane to the long-term survival of the human race?

The theory of natural selection has it that individuals with better genes tend to survive and reproduce, passing their genes to their offspring. This gradual process results in a population more ...
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2answers
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Are human males and females more genetically different than members of other species?

I'm looking at this Ted talk about a Saudi Arabia woman who dared to drive a car in the last few years. This reminds me that until the last century or so, women (all over the world?) enjoyed less ...
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2answers
594 views

Initial population when i count backwards?

My question is dealing with how many ancestors it took to produce me: --> to produce me it took 2 people (my parents) = ($2^1$) people = 2 --> one generation further included = ($2^1 + 2^2$) people =...
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How come most animals never seem to evolve over millenia?

People often say, including those with extensive knowledge in biology, that a certain species of animal will evolve in one way or another: 1.From changing environments. 2.Mutations. 3.Possibly even ...
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1answer
700 views

What hair color will result in someone inheriting both blond and ginger genes?

Both the genes for blond hair and ginger hair are recessive, so they need both parents to give the same gene for it to take affect. What happens when a person has 1 copy of a recessive gene and ...
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1answer
103 views

What is the difference between a Human Being, Homo Sapiens and a Neanderthal?

I know that the Neanderthal's are a branch of the Human Being but how do all three relate to each other or more specifically what is the difference?
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48 views

Genetics of epilepsy

Is epilepsy genetically inheritable? If yes, is it dominant?
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186 views

Skin color explanation?

I do not understand how skin color in humans work, even after taking a basic genetics course and reading some on wikipedia. From what I understand, skin is color based on multiple genes that control ...
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3answers
2k views

What is the difference between eugenics and evolution by natural selection?

So with the working definition of Eugenics: "the aim to improve the human gene pool". What are key features that distinguish Eugenics from evolution by natural selection? I mean, besides that natural ...
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1answer
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Perplexing by the way of estimating the shared or different genes between humans and chimps

We share 98.5% genes with chimps (it means we have 98.5% same DNA sequeces ),so there is about one percent difference .It means we can approximately differ from them by one base pair every hundred ...
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94 views

How to determine genotype?

In humans, the ability or inability to roll the tongue is a single gene trait. The allele for tongue rolling (R) is dominant to the allele for not being able to roll the tongue (r). Whether or ...
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Inheritance patterns in individuals with triploidy

If you search on the genetics of Down's Syndrome, you'll find plenty of results explaining the genetic mechanisms which can result in triploidy. However, I can't find any information on the ...
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144 views

Do transposons usually jump from one chromosome to another?

If it is usual occurrence, does it mean that my one gene can change its location from one chromosome to another?
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Can genetically engineering the DNA of a human zygote, make it a twin of another human in entirety?

My question is simple. If I wanted to make an exact twin of an individual, will genetically engineering the DNA of the zygote to match with the individual suffice?
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719 views

How does Humira work when injected into patients with rheumatoid arthritis?

OK, I have rheumatoid arthritis and I've been injecting Humira 2 times a month for the last 8 months. As far as I know rheumatoid arthritis is simply an immune system disorder which makes the immune ...
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77 views

How Much DNA do Siblings whose Parents are First Cousins Share?

On average, two siblings generally share 50% of their genome. How much does this increase if the siblings' parents are first cousins?
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85 views

How likely is it that a person's progeny has an inheritable disorder based on this pedigree?

Case study: A person (let's just call him "John") had 3 aunts that died back in the 1950's in early childhood due to an unknown form of neuromuscular disorder. One died at birth, one at 2 years and ...
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140 views

Why do haemophillic females $X^hX^h$ die before birth?

I just came across a statement in my book , while reading genetics, that haemophiliac females do not survive till birth (the reason not mentioned here why) . Before posting this question here I ...
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Is there a realistic “family tree” model for the human population?

I would like to do some gene inheritance simulations, and I was wondering if there is an accepted model for what mating looks like in the general human population? I am not necessarily looking for the ...
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1answer
557 views

What factors govern the variable age of onset in Huntington's Disease?

"Huntington's disease (HD) is a neurodegenerative genetic disorder that affects muscle coordination and leads to cognitive decline and psychiatric problems." As we all know, this genetic disease ...
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92 views

Predictable microchimerism

I read in New Scientist recently that microchimerism occurs between previously born siblings and grandparents, not just the mother. Do we know which parts of the genome are likely to be transferred? ...
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42 views

Forensic genetics- why is mtDNA comparison sometimes better than nDNA comparison?

Why is (in forensic genetics) in some cases more appropriate comparison of nuclear DNA but in some other cases comparison of mitochondrial DNA? Is it because geneticists are sometimes unable to find ...
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Regeneration capabilities in humans?

To what extent can humans, (mammals in general), theoretically regenerate, and is their a way to speed up and/or exceed this original extent.
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Runs of homozygosity - degree of inbreeding and disease associations

Been reading recently about methods to determine how inbred a particular person is by measuring their "runs of homozygosity." Loosly, these are defined as regions of the genome (typically >1Mb) where ...
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Why is down syndrome more common than other trisomies? [duplicate]

Why is Down syndrome more common than say trisomy 18? Is chromosome 21 easier to replicate? Or is it because those babies are more viable?
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What would the resulting karyotype be if someone with Klinefelter syndrome fertilized an “empty” egg?

Endoreduplication: is a form of nuclear polyploidization that results in multiple, uniform copies of chromosomes. This process is common in plants and animals, especially in tissues with high ...
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In what way is ADHD genetic? [closed]

According to Psychcentral depression, bipolar disorder, ADHD, schizophrenia and autism are traceable to the same inherited genetic variations According to AsapSCIENCE, depression could be genetic due ...
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136 views

Current Trend in Evolution of Human Intelligence

Up front, I am specifically not interested in philosophical or ethical considerations re Eugenics and related concepts. In an effort to receive a concise answer I'll post a narrowly defined question ...
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Which information can be obtained from a list of gene names?

Lets say I only have a list of gene names. I know they are up regulated and I know they are related to cancer. What information can I obtain from having only the names of genes? For example is there ...
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1answer
223 views

Is it really detrimental to humans as a species to reproduce with one's own first cousin?

Tired of hearing of these urban legends and popular opinions, I ask this question here to see if there really is scientific merit to this belief. My questions is, is it really "harmful" for a person ...
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1answer
131 views

What does it mean to clone a gene?

When I look up information related to the identification of disease genes, texts will often refer to the gene being "first cloned." What does "clone" mean in this context? Is it simply a synonym for ...
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3answers
85 views

How valid is the theory of human's chimp-pig origin? [closed]

Edit: I have also asked the question on skeptics.stackexchange.com and it has been answered there. Here is the link. There is a person called Dr. Eugene McCarthy who has a theory that the origin of ...
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2answers
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How many recombination events are there per generation in humans?

I'm looking for a reference that tells me how many recombenation events occur in humans from one generation to the next. Assuming that the human genome is a 3.3 GigaBases long DNA sequence, how many ...
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1answer
412 views

Is tongue rolling genetic?

Is the ability to roll your tongue or not truly inherited or genetic? What I have gathered from school has been contradicting with evidence I found elsewhere.
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1answer
1k views

What do rs id, allele coded 0 and allele coded 1 mean?

So, for a project I've been working on (different story), I've been looking at the HapMap Project, and their free online files. In their README file, they talk about how for each legend file for each ...
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Markers for human genetic mapping

For human genetic mapping several different types of markers are used: RFLPs (Restriction Fragment Length Polymorphisms) VNTRs (Variable Number of Tandem Repeats) such as mini- and microsatellites ...