The scientific study of inheritance as it occurs specifically in human beings.

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Recessiveness of allele for protection of organism

Heterozygous organisms profit from pairs of gene alleles. Harmful alleles when being recessive can be carried without any harm for the organism. Only when two harmful recessive alleles form a gene the ...
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6answers
127 views

Which information can be obtained from a list of gene names?

Lets say I only have a list of gene names. I know they are up regulated and I know they are related to cancer. What information can I obtain from having only the names of genes? For example is there ...
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2answers
1k views

The Uniqueness of DNA Paradox

How can everyone have unique iris and fingerprints? After a certain amount of human beings have lived on earth, wouldn't it be possible to exhaust all possible combinations? The same principle ...
2
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0answers
44 views

Can DNA test of my grandparent's brother reveal my heritage from that branch of the family?

I'm thinking about doing that DNA test on all my grandparents to know where their genes come from. They are getting very old and I don't want to let the opportunity pass to gather more knowledge about ...
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0answers
42 views

Horizontal gene transfer from humans

It is known that some viruses embed themselves in the human genome. Is there a mechanism by which human genes can be transferred to other animals or plants by means of viruses shuttling them from ...
2
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1answer
13 views

MTHFR recessive alleles and B-vitamins

I know that being heterozygous or homozygous recessive for the MTHFR gene prevents that person from being able to process and use folate and B-12. It causes an unhealthy level of homocysteine to ...
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0answers
48 views

Is human reaction time really allmost purely genetic?

I am playing a video game at the moment where reaction time is really important. So I started testing my reaction time using this application: http://humanbenchmark.com/tests/reactiontime. I was ...
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3answers
60 views

DIY storing family DNAs' samples for future uses (eg medical)

I have a question I could not get an understandable reply from Google and I am no expert in the matter, so my plead to you is if you could give me practical and relatively easy to follow advice. With ...
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0answers
41 views

Would it be possible to create a gel, holding viruses, that could alter human genetic code when rubbed in?

I was wondering if it could be possible to engineer a virus, that when it comes into contact with human hair follicles, it could alter someones natural hair color. Naturally blue hair anyone? ...
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1answer
30 views

Can we produce synthetic red blood cells lacking antigens?

I had an idea come to me during Biology class and I immediately asked my teacher, but she couldn't really answer the question, so I'll ask it here. What are the limiting factors in the production of ...
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3answers
157 views

If a gene is located on the X sex chromosome does that mean males are either Homozygous dominant or Homozygous recessive and are never Heterozygous?

As said in the title I am a little confused on the Idea of traits located on the sex chromosomes. The example we worked on in class was hemophilia a recessive trait and since it is located on the X ...
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2answers
533 views

Father with mutated mtDNA- why isn't his offspring at risk?

Mothers transmit their mitochondria (and therefore mtDNA) to their offspring and fathers don't. Lets assume that father had a mutation of the gene that encodes mtDNA, would then be his offspring at ...
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1answer
75 views

Proving time travel

Consider this answer to an interesting question. It's not possible to prove completely that someone is the descendant of someone else, there's always a nonzero probability that the results are a ...
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0answers
38 views

Y Chromosome in Ovary Cancer Data

I have been analyzing TCGA Ovary Cancer data. In Somatic Mutation data, there is data of mutations in all the chromosomes (1-22 and X), but amazingly, I have found one (just one) row of Y Chromosome ...
5
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2answers
62 views

GWAS: why is replication in another cohort so crucial?

Almost all the landmark GWAS (Genome-Wide Association Studies) reviews agree that, for a GWAS finding to be valid, it needs to be replicated in an independent cohort. What exactly is the rationale ...
3
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0answers
60 views

Current Trend in Evolution of Human Intelligence

Up front, I am specifically not interested in philosophical or ethical considerations re Eugenics and related concepts. In an effort to receive a concise answer I'll post a narrowly defined question ...
3
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1answer
32 views

Forensic genetics- why is mtDNA comparison sometimes better than nDNA comparison?

Why is (in forensic genetics) in some cases more appropriate comparison of nuclear DNA but in some other cases comparison of mitochondrial DNA? Is it because geneticists are sometimes unable to find ...
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5answers
5k views

Do humans have enough biological differences to be grouped into races or subspecies?

After my online research on the subject, I learnt that, biologically speaking, many scientists believe that there is no such thing as a race. Homo sapiens as a species is only 200,000 years old, which ...
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0answers
54 views

Swapping genes?

So, gene therapy is to take out a gene, correct its mutation, and put the corrected one back into the organism, right? Is it also possible to take out a gene from an organism and put in a totally ...
2
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1answer
53 views

Markers for human genetic mapping

For human genetic mapping several different types of markers are used: RFLPs (Restriction Fragment Length Polymorphisms) VNTRs (Variable Number of Tandem Repeats) such as mini- and microsatellites ...
5
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1answer
86 views

Understanding recombination scoring in family pedigrees

I am having some problems understanding recombination, and I am not sure what element I am missing here. This figure is an example from my text book. The pedigree belongs to a family with an autosomal ...
3
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1answer
34 views

How to determine genotype?

In humans, the ability or inability to roll the tongue is a single gene trait. The allele for tongue rolling (R) is dominant to the allele for not being able to roll the tongue (r). Whether ...
3
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1answer
50 views

Why do haemophillic females $X^hX^h$ die before birth?

I just came across a statement in my book , while reading genetics, that haemophiliac females do not survive till birth (the reason not mentioned here why) . Before posting this question here I ...
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0answers
9 views

Plants and animals ability to survive polypoidy conditions [duplicate]

In mammals the condition polyploidy produce something euphemistically termed "general developmental disruption" ,practically speaking this means system meltdown which happens very quickly. There is ...
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1answer
18 views

What do we use as baseline to determine what genetic segments are “mutations” (and what are not)

In order to determine whether a particular segment of genetic code is a mutation, there must first be a baseline code on which that code looks somehow different. How has the baseline code been ...
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1answer
71 views

How far can we go in engineering our own evolution? [closed]

After recently seeing Christopher Nolan's Interstellar and reading Kip Thorne's The Science of Interstellar, I've seriously been reflecting on the challenges mankind faces in becoming space pioneers, ...
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2answers
56 views

Can genetically engineering the DNA of a human zygote, make it a twin of another human in entirety?

My question is simple. If I wanted to make an exact twin of an individual, will genetically engineering the DNA of the zygote to match with the individual suffice?
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20 views

How can I classify Breast Cancer if I have incomplete receptor information?

I have a clinical data table for a cohort of Breast Cancer patients and I want to classify them as being either triple negative or triple positive. You can find the file here. For some of the ...
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2answers
425 views

What is biological dark matter?

I recently stumbled upon the Biological Dark Matter wiki page. Its pretty light on details, but it appears to be genetic material found in humans that doesn't fall into currently classifications. ...
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0answers
58 views

How does a baby retain a blood group different from it's mother, in her womb?

It's a well-established fact that blood group is decided by genotype. But, when a new child starts it's journey in the womb, then the mother's blood (along with it's agglutinins and agglutinogens) ...
4
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1answer
99 views

Redheads and pain receptors

I remember reading this in a biology textbook, and decided to do a little digging. Redheads have a lower sensitivity to some pain and a higher sensitivity to other compared to people of other colored ...
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3answers
40 views

How do scientists decide which version of a polymorphism is the main one?

This in fact has bugged me for years, but now I finally remembered to ask. I suppose that if one variation is more frequent, it can be labeled as the default, but what about variations that are ...
8
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1answer
159 views

Why aren't green eyes more prevalent?

Why aren't green eyes more prevalent, given that the green allele is dominant over the blue one? My understanding is that human eye colour is determined by two genes: 1) HERC2, with alleles Bx, BB ...
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0answers
18 views

Question about clusters and populations [closed]

Whats the difference between a cluster and a population?...and do non africans cluster together? Examples European populations or the niger congo cluster.
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201 views

Is the function of adjacent genes correlated?

Do genes that occupy a similar locus on the genome have correlated function, specifically in human beings? It is my understanding that adjacent genes are inherited together, and so location plays a ...
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2answers
443 views

What effect does the Barr body have, in relation to female Turner syndrome?

Why do persons with Turner syndrome have developmental abnormalities, when normal XX-females do not, even though they only have 1 active X chromosome? From what I know, one X-chromosome is ...
4
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1answer
162 views

Why isn't Rh disease present in other mammals?

I have read about Rhesus D Hemolytic Disease of the Newborn, sometimes called "Rh disease". It's rare, but it can happen when an Rh+ baby is conceived by an Rh- mother. This raises many questions. I ...
4
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1answer
79 views

A colony of humans are sent to an alien world, at what point would the descendants evolve to be genetically incompatible with Earth humans? [closed]

I recently heard about the evolution of the London Underground mosquitoes, and how they have changed genetically enough that they almost can no longer reproduce with above ground mosquitos. Since this ...
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2answers
212 views

Why do we have more male infant born?

For every 104 male babies,we have 100 female babies and there is a Statistics which is more reliable (we have 997 female infant born per 1000 male infant born). what's the reason? why do we have male ...
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1answer
132 views
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4answers
431 views

How come most animals never seem to evolve over millenia?

People often say, including those with extensive knowledge in biology, that a certain species of animal will evolve in one way or another: 1.From changing environments. 2.Mutations. 3.Possibly even ...
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0answers
53 views

If two people look alike, is there probability that somewhere in their ancestry there was inter-breeding?

If two people who're otherwise not related but still look a lot alike, is there a probability that somewhere in there ancestry there was an inter-breeding that took place?
2
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0answers
52 views

Are the Chromosomes organized in any meaningful way? [closed]

So my major is in pharmacy but both my master and my (currently in progress) doctoral degree are both in theoretical chemistry. My thesis is about quantum chemistry and proteins, but it has a certain ...
4
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1answer
223 views

Why are irises unique?

I heard that irises are different and unique for every person. According this link, probability of two irises having identical pattern is 1 in 10 to the 78th power. That's how iris scanners identify ...
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1answer
91 views

Possibility of Human cloning

Technology has evolved so much as to clone animals. But, what about human cloning? Is it really possible to create humans in lab? Or is it that technology has not advanced to that level..? Why cant ...
3
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2answers
208 views

How does Humira work when injected into patients with rheumatoid arthritis?

OK, I have rheumatoid arthritis and I've been injecting Humira 2 times a month for the last 8 months. As far as I know rheumatoid arthritis is simply an immune system disorder which makes the immune ...
3
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1answer
379 views

Like other animals, why humans don't have species & breeds?

Like other animals, why don't humans have species & breeds ? Even my pet dog is one type of breed, but we (humans) lack breeds & species? What is the main reason?
6
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1answer
420 views

Why did humans lose their fur?

The little amount of body hair humans have don't seem to be of much use for keeping warm. Our Simian cousins on the other hand sport thick furs. At which point during the species evolution and why ...
4
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2answers
270 views

The gender of offspring of Twins?

Given identical twin males, Michael and Douglas, Douglas and his wife have four children, all of whom are girls. Michael and his wife have only one child, a boy, and are expecting another. What are ...
3
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3answers
679 views

What is the difference between eugenics and evolution by natural selection?

So with the working definition of Eugenics: "the aim to improve the human gene pool". What are key features that distinguish Eugenics from evolution by natural selection? I mean, besides that natural ...