The scientific study of inheritance as it occurs specifically in human beings.

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Proving time travel

Consider this answer to an interesting question. It's not possible to prove completely that someone is the descendant of someone else, there's always a nonzero probability that the results are a ...
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How to determine genotype?

In humans, the ability or inability to roll the tongue is a single gene trait. The allele for tongue rolling (R) is dominant to the allele for not being able to roll the tongue (r). Whether ...
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MTHFR recessive alleles and B-vitamins

I know that being heterozygous or homozygous recessive for the MTHFR gene prevents that person from being able to process and use folate and B-12. It causes an unhealthy level of homocysteine to ...
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If a gene is located on the X sex chromosome does that mean males are either Homozygous dominant or Homozygous recessive and are never Heterozygous?

As said in the title I am a little confused on the Idea of traits located on the sex chromosomes. The example we worked on in class was hemophilia a recessive trait and since it is located on the X ...
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Why do haemophillic females $X^hX^h$ die before birth?

I just came across a statement in my book , while reading genetics, that haemophiliac females do not survive till birth (the reason not mentioned here why) . Before posting this question here I ...
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Plants and animals ability to survive polypoidy conditions [duplicate]

In mammals the condition polyploidy produce something euphemistically termed "general developmental disruption" ,practically speaking this means system meltdown which happens very quickly. There is ...
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18 views

What do we use as baseline to determine what genetic segments are “mutations” (and what are not)

In order to determine whether a particular segment of genetic code is a mutation, there must first be a baseline code on which that code looks somehow different. How has the baseline code been ...
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53 views

How far can we go in engineering our own evolution? [closed]

After recently seeing Christopher Nolan's Interstellar and reading Kip Thorne's The Science of Interstellar, I've seriously been reflecting on the challenges mankind faces in becoming space pioneers, ...
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48 views

Can genetically engineering the DNA of a human zygote, make it a twin of another human in entirety?

My question is simple. If I wanted to make an exact twin of an individual, will genetically engineering the DNA of the zygote to match with the individual suffice?
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How can I classify Breast Cancer if I have incomplete receptor information?

I have a clinical data table for a cohort of Breast Cancer patients and I want to classify them as being either triple negative or triple positive. You can find the file here. For some of the ...
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87 views

What is biological dark matter?

I recently stumbled upon the Biological Dark Matter wiki page. Its pretty light on details, but it appears to be genetic material found in humans that doesn't fall into currently classifications. ...
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How does a baby retain a blood group different from it's mother, in her womb?

It's a well-established fact that blood group is decided by genotype. But, when a new child starts it's journey in the womb, then the mother's blood (along with it's agglutinins and agglutinogens) ...
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67 views

Redheads and pain receptors

I remember reading this in a biology textbook, and decided to do a little digging. Redheads have a lower sensitivity to some pain and a higher sensitivity to other compared to people of other colored ...
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How do scientists decide which version of a polymorphism is the main one?

This in fact has bugged me for years, but now I finally remembered to ask. I suppose that if one variation is more frequent, it can be labeled as the default, but what about variations that are ...
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130 views

Why aren't green eyes more prevalent?

Why aren't green eyes more prevalent, given that the green allele is dominant over the blue one? My understanding is that human eye colour is determined by two genes: 1) HERC2, with alleles Bx, BB ...
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18 views

Question about clusters and populations [closed]

Whats the difference between a cluster and a population?...and do non africans cluster together? Examples European populations or the niger congo cluster.
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Is the function of adjacent genes correlated?

Do genes that occupy a similar locus on the genome have correlated function, specifically in human beings? It is my understanding that adjacent genes are inherited together, and so location plays a ...
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156 views

What effect does the Barr body have, in relation to female Turner syndrome?

Why do persons with Turner syndrome have developmental abnormalities, when normal XX-females do not, even though they only have 1 active X chromosome? From what I know, one X-chromosome is ...
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489 views

Father with mutated gene for mtDNA- why isn't his offspring at risk?

Mothers transmit their mitochondria (and therefore mtDNA) to their offspring and fathers don't. Lets assume that father had a mutation of the gene that encodes mtDNA, would then be his offspring at ...
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154 views

Why isn't Rh disease present in other mammals?

I have read about Rhesus D Hemolytic Disease of the Newborn, sometimes called "Rh disease". It's rare, but it can happen when an Rh+ baby is conceived by an Rh- mother. This raises many questions. I ...
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A colony of humans are sent to an alien world, at what point would the descendants evolve to be genetically incompatible with Earth humans? [closed]

I recently heard about the evolution of the London Underground mosquitoes, and how they have changed genetically enough that they almost can no longer reproduce with above ground mosquitos. Since this ...
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5answers
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Do humans have enough biological differences to be grouped into races or subspecies?

After my online research on the subject, I learnt that, biologically speaking, many scientists believe that there is no such thing as a race, because Homo sapiens species is only 200,000 years old, ...
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184 views

Why do we have more male infant born?

For every 104 male babies,we have 100 female babies and there is a Statistics which is more reliable (we have 997 female infant born per 1000 male infant born). what's the reason? why do we have male ...
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385 views

How come most animals never seem to evolve over millenia?

People often say, including those with extensive knowledge in biology, that a certain species of animal will evolve in one way or another: 1.From changing environments. 2.Mutations. 3.Possibly even ...
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If two people look alike, is there probability that somewhere in their ancestry there was inter-breeding?

If two people who're otherwise not related but still look a lot alike, is there a probability that somewhere in there ancestry there was an inter-breeding that took place?
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Are the Chromosomes organized in any meaningful way? [closed]

So my major is in pharmacy but both my master and my (currently in progress) doctoral degree are both in theoretical chemistry. My thesis is about quantum chemistry and proteins, but it has a certain ...
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135 views

Why are irises unique?

I heard that irises are different and unique for every person. According this link, probability of two irises having identical pattern is 1 in 10 to the 78th power. That's how iris scanners identify ...
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87 views

Possibility of Human cloning

Technology has evolved so much as to clone animals. But, what about human cloning? Is it really possible to create humans in lab? Or is it that technology has not advanced to that level..? Why cant ...
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177 views

How does Humira work when injected into patients with rheumatoid arthritis?

OK, I have rheumatoid arthritis and I've been injecting Humira 2 times a month for the last 8 months. As far as I know rheumatoid arthritis is simply an immune system disorder which makes the immune ...
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300 views

Like other animals, why humans don't have species & breeds?

Like other animals, why don't humans have species & breeds ? Even my pet dog is one type of breed, but we (humans) lack breeds & species? What is the main reason?
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260 views

Why did humans lose their fur?

The little amount of body hair humans have don't seem to be of much use for keeping warm. Our Simian cousins on the other hand sport thick furs. At which point during the species evolution and why ...
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236 views

The gender of offspring of Twins?

Given identical twin males, Michael and Douglas, Douglas and his wife have four children, all of whom are girls. Michael and his wife have only one child, a boy, and are expecting another. What are ...
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545 views

What is the difference between eugenics and evolution by natural selection?

So with the working definition of Eugenics: "the aim to improve the human gene pool". What are key features that distinguish Eugenics from evolution by natural selection? I mean, besides that natural ...
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267 views

How do the pharmacodynamics of the NSAIDs differ and are there “resistant” COX phenotypes?

I know that the non-steroidal anti-inflammatory drugs (e.g., aspirin, ibuprofen, naproxen) affect the enzymes cyclooxygenase (types I and II). Is there any difference in the degree to which these ...
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Can sealed epiphyseal growth plates theoretically be restored via epigenetic or genetic methods?

I know that epiphyseal growth plates seal up once people become young adults and that it is currently impossible to restore them to actively produce new bone growth but, is it theoretically possible ...
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33 views

Cell targets of Glybera

So we know that there is a first gene therapy drug in the market out there called Alipogene tiparvovec to address lipoprotein lipase deficiency (LPLD) at a genetic level. Does this genetic drug ...
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213 views

Why has grey hair evolved?

A vast majority of humans get at least some grey hair as they age. As far as I know this applies to both genders and all races. Presumably this means that at least some grey haired humans have ...
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Why are men stronger than women?

What are the evolutionary explanations for why women are weaker than men (on average), and is this difference adaptive? See figure one here. I suppose that something puts pressure on men to be ...
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Why doesn't the human skin grow back exactly how it was before being damaged?

Very simple: Why (and how) is regenerated skin different from original ? As we know we lose skin cells that becomes the dust in out homes and it always grows back to full thickness right ? So when I ...
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140 views

Is there some genetic variance underlying music appreciation?

Is there any research done on the genetic variance for Music appreciation? If not, why is there no genetic variance for this trait?
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749 views

Why do humans seem so much more prone to disease than animals? [closed]

It seems like when we observe animals in the wild, the occurrence of noticeable disease in adult individuals is much lower than in humans. Why? There are a number of reasons that this could happen, ...
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27 views

Is there a realistic “family tree” model for the human population?

I would like to do some gene inheritance simulations, and I was wondering if there is an accepted model for what mating looks like in the general human population? I am not necessarily looking for the ...
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Implications of what the discovery of Naia means

Recently a discovery was made of a ~12,000 year old girl in Hoyo Negro in Mexico. This has been covered by many different news agencies. I'm confused however by many of the reports. Does it ...
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536 views

Did the eugenics program in Nazi Germany have a measurable effect? [closed]

Did the killing or sterilisation of people considered as living a "life unworthy of life" in Nazi Germany have any measurable effect on the "average health" of Germany? Is there any statistical ...
5
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1answer
302 views

Would a spinal injury decrease human height?

A woman I know has been losing height at a rate of few cm a year following a severe spinal injury. How is this possible? What kind of injury could cause such progressive loss of height? Could this be ...
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137 views

Schedules of mating for men

It’s simple deductive logic to follow that for a species to survive it must provide it’s offspring with the best possible conditions to ensure it’s survival – either that or to reproduce in such ...
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34 views

Will a vasectomy prevent genetic engineering of a child?

Making the assumption: Within 10 years, an adult will be able to genetically engineer (modify, enhance, clean, etc.) a child from their own DNA (and the DNA of a non-related partner). then would ...
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How many people are required to maintain genetic diversity?

Imagine humans were to colonize a distant planet and it was a single one-way trip. How many people would they need to bring? Obviously 2 is the minimum, but that would result in a lot of inbreeding. ...
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Alleles notation in SNPPedia criteria

I can understand the allele notation when is in the form rs8176719(T;T) or rs8176719(G) but recently i found this ones rs8176719(T;-) or rs8176719(-;T). So im confused, rs8176719(T;-) is the same as ...