The scientific study of inheritance as it occurs specifically in human beings.
3
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1answer
66 views
Why are certain aneuploidies more common?
Certain aneuploidies such as trisomy-21 (Downs syndrome), trisomy-18 (Edward syndrome), Turner syndrome (XO) etc are more common than others.
I had a vague thought that it is related to chromosome ...
2
votes
1answer
51 views
Hardy-Weinberg Equilibrium: To compute probability of finding two siblings (random mating)
I've been working a little with M. G. Bulmer's Principles of Statistics (Dover, 1979) and cannot see how to properly compute half of one question. This should be a basic probability computation, but I ...
3
votes
1answer
48 views
What factors govern the variable age of onset in Huntington's Disease?
"Huntington's disease (HD) is a neurodegenerative genetic disorder that affects muscle coordination and leads to cognitive decline and psychiatric problems." As we all know, this genetic disease ...
3
votes
1answer
48 views
Regeneration capabilities in humans?
To what extent can humans, (mammals in general), theoretically regenerate, and is their a way to speed up and/or exceed this original extent.
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1answer
34 views
Are there any studies of epigenetic difference between twins during their lifespan?
Are there any studies of epigenetic difference between twins during their lifespan ? I ask because I wonder if there exist phases during lifespan, when environmental factors plays major role ...
4
votes
1answer
84 views
What is a Mitochondrial Eve and Y-chromosomal Adam
I've read this question:
What kind of event would cause the current Mitochondrial Eve to be replaced by a new one?
And the values in Wikipedia about Mitochondrial Eve and Y-chromosomal Adam and I am ...
2
votes
1answer
59 views
Why do genitals feel frozen when freefalling?
I don't want to add much more about that. Since childhood I noticed a chilling effect, even when doing rollercoaster-type activities.
8
votes
2answers
84 views
Is there any difference in terms of personal healthcare between complete DNA sequencing and SNPs genotyping?
There are several companies (most notably 23andMe) providing SNP genotyping for individuals claiming that there is no sense for individual in obtaining full genome sequence since only small part of it ...
8
votes
3answers
196 views
What kind of event would cause the current Mitochondrial Eve to be replaced by a new one?
Apparently all living humans are matrilineal descendants of a single woman who lived 200.000 years ago. She is called Mitochondrial Eve.
But at the time she lived there was a different matrilineal ...
9
votes
1answer
118 views
How many people are required to maintain genetic diversity?
Imagine humans were to colonize a distant planet and it was a single one-way trip. How many people would they need to bring?
Obviously 2 is the minimum, but that would result in a lot of inbreeding.
...
6
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1answer
726 views
Will a bone marrow transplant change one's blood type?
Will a bone marrow transplant change one's blood type?
Or is the donor blood type matched with the person before transplant?
2
votes
1answer
73 views
Have there been any experiments that duplicate chromosome copies from 23*2 to 23*3 or 23*4?
Deinococcus radiodurans is an amazing bacterium with a fantastic survival rate. It can survive to high doses of radiation, in a complete vacuum and in hydrochloric acid.
How does this bacterium ...
4
votes
0answers
102 views
How do the pharmacodynamics of the NSAIDs differ and are there “resistant” COX phenotypes?
I know that the non-steroidal anti-inflammatory drugs (e.g., aspirin, ibuprofen, naproxen) affect the enzymes cyclooxygenase (types I and II).
Is there any difference in the degree to which these ...
2
votes
1answer
38 views
PGC-1β Sod2 limiters/blockers
I'd like to block a percentage of PGC-1β or Sod2 expression. According to the following paper's figure beta-blockers inhibit some expression of PGC-1α. Are there any medicines/chemicals which safely ...
2
votes
2answers
80 views
Is better healthcare a bane to the long-term survival of the human race?
The theory of natural selection has it that individuals with better genes tend to survive and reproduce, passing their genes to their offspring. This gradual process results in a population more ...
6
votes
3answers
136 views
Are there genes in humans from the common ancestor of all organisms?
How long ago can human genes be traced? Are there any genes that go back unchanged to the beginning of life on Earth? And if so, how many?
0
votes
0answers
72 views
why genetics R&D advances so slowly? [closed]
I'm aware this question may sound stupid but I'm wondering why the research & development in genetics is advancing so slowly compared with the IT world. Is it a problem of funding , ethics, ...
3
votes
1answer
68 views
Predictable microchimerism
I read in New Scientist recently that microchimerism occurs between previously born siblings and grandparents, not just the mother.
Do we know which parts of the genome are likely to be transferred? ...
5
votes
1answer
122 views
Is ovum + ovum fertilization possible for human?
In humans is it possible to fertilize a ovum with another ovum from the same female subject?
I already found some works in which the ovum is fertilized by a somatic cell (see e.g. this ), but I am ...
7
votes
1answer
79 views
Is the function of adjacent genes correlated?
Do genes that occupy a similar locus on the genome have correlated function, specifically in human beings? It is my understanding that adjacent genes are inherited together, and so location plays a ...
8
votes
2answers
107 views
What is the contribution of viruses to the evolution of mankind?
I'm interested in horizontal gene transfer in bacteria, viruses, and organisms such as Bdelloid Rotifers. I've just read in Carl Zimmer's 'A Planet of Viruses' the following passage:
As a host ...
4
votes
1answer
95 views
Can humans shorten their sleeping patterns?
Can sleeping patterns be trained, or are they genetic? I read that a human needs to sleep at least 4 hours. Can sleeping time be reduced without having a negative impact?
10
votes
3answers
189 views
Number of beneficial mutations cataloged?
I can see from Wikipedia that there are possibly thousands of harmful mutations that have been cataloged and linked to disease. There are also unnumbered neutral mutations. But, does anyone know how ...
6
votes
4answers
113 views
Genetic effects on personality
It is said that genes are partly responsible for the choices we make in our life; our genes help to create our environment, and then that environment can influence our personality. So, beside genes, ...
1
vote
1answer
69 views
Generating custom human DNA sequences based on traits such as eye colour?
I'm wondering if it would be possible to create software (unless some already exists, but I couldn't find any) to generate human DNA (the base pairs on the double helix) containing genes representing ...
12
votes
4answers
328 views
Questions to ask to a panel of people that will be sequenced
Some genes have been shown to be associated with left-handedness.
Working with some clinicians, I've recommend them to ask their patients (whose genome will be sequenced) if they are "right or ...
5
votes
2answers
246 views
How are the gene sequences of individual sperm and egg cells “randomized”?
What I mean by "randomized" is, in the place where an egg cell or sperm cell is made, what is the mechanism by which each one is not made identically? Though I am a layman, I'm pretty sure that if the ...
8
votes
2answers
1k views
How is eye color in humans inherited?
In high school we studied the inheritance of eye color, as it was explained to us in the most simple way: blue eye color is a recessive, monogenic, autosomal trait. Now I know that it is a bit more ...
