The scientific study of inheritance as it occurs specifically in human beings.

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2answers
3k views

How many people are required to maintain genetic diversity?

Imagine humans were to colonize a distant planet and it was a single one-way trip. How many people would they need to bring? Obviously 2 is the minimum, but that would result in a lot of inbreeding. ...
13
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2answers
227 views

What is the contribution of viruses to the evolution of mankind?

I'm interested in horizontal gene transfer in bacteria, viruses, and organisms such as Bdelloid Rotifers. I've just read in Carl Zimmer's 'A Planet of Viruses' the following passage: As a host ...
12
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4answers
423 views

Questions to ask to a panel of people that will be sequenced

Some genes have been shown to be associated with left-handedness. Working with some clinicians, I've recommend them to ask their patients (whose genome will be sequenced) if they are "right or ...
11
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3answers
323 views

Number of beneficial mutations cataloged?

I can see from Wikipedia that there are possibly thousands of harmful mutations that have been cataloged and linked to disease. There are also unnumbered neutral mutations. But, does anyone know how ...
10
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2answers
2k views

How is eye color in humans inherited?

In high school we studied the inheritance of eye color, as it was explained to us in the most simple way: blue eye color is a recessive, monogenic, autosomal trait. Now I know that it is a bit more ...
9
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5answers
3k views

Do humans have enough biological differences to be grouped into races or subspecies?

After my online research on the subject, I learnt that, biologically speaking, many scientists believe that there is no such thing as a race, because Homo sapiens species is only 200,000 years old, ...
9
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1answer
107 views

Is there any evidence that humans have faced extinction before?

Have we as a species faced extinction in the past? Resulting in a 'population bottleneck'? If so, what genetic evidence is there of this occurring?
9
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2answers
146 views

Is there any difference in terms of personal healthcare between complete DNA sequencing and SNPs genotyping?

There are several companies (most notably 23andMe) providing SNP genotyping for individuals claiming that there is no sense for individual in obtaining full genome sequence since only small part of it ...
9
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1answer
97 views

Why do so many people have group O blood?

Please forgive me in case my question wouldn't make much sense. I was reading about ABO blood groups on Wikipedia, where I learnt that O is a recessive allele, and that it seems the A allele predates ...
9
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1answer
327 views

Did the eugenics program in Nazi Germany have a measurable effect? [closed]

Did the killing or sterilisation of people considered as living a "life unworthy of life" in Nazi Germany have any measurable effect on the "average health" of Germany? Is there any statistical ...
8
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1answer
493 views

Could humans and chimpanzees hybridize?

In some cases two species can hybridize. For example, Tigers and lions can hybridize to produce "Ligers". Would it also be possible for humans and chimpanzees (or any other species) to hybridize ? ...
8
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3answers
274 views

What kind of event would cause the current Mitochondrial Eve to be replaced by a new one?

Apparently all living humans are matrilineal descendants of a single woman who lived 200.000 years ago. She is called Mitochondrial Eve. But at the time she lived there was a different matrilineal ...
8
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1answer
238 views

How do the pharmacodynamics of the NSAIDs differ and are there “resistant” COX phenotypes?

I know that the non-steroidal anti-inflammatory drugs (e.g., aspirin, ibuprofen, naproxen) affect the enzymes cyclooxygenase (types I and II). Is there any difference in the degree to which these ...
7
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1answer
157 views

Is the function of adjacent genes correlated?

Do genes that occupy a similar locus on the genome have correlated function, specifically in human beings? It is my understanding that adjacent genes are inherited together, and so location plays a ...
6
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3answers
271 views

Are there genes in humans from the common ancestor of all organisms?

How long ago can human genes be traced? Are there any genes that go back unchanged to the beginning of life on Earth? And if so, how many?
6
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3answers
211 views

Genetic effects on personality

It is said that genes are partly responsible for the choices we make in our life; our genes help to create our environment, and then that environment can influence our personality. So, beside genes, ...
6
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3answers
162 views

Why are males more likely than females to have autism spectrum disorder?

The male to female ratio in autism spectrum disorder is around 4:1. However it seems ASD is not a simple X-linked disorder. Then how is it possible males are more susceptible than females, if the ...
6
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2answers
523 views

How are the gene sequences of individual sperm and egg cells “randomized”?

What I mean by "randomized" is, in the place where an egg cell or sperm cell is made, what is the mechanism by which each one is not made identically? Though I am a layman, I'm pretty sure that if the ...
6
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1answer
7k views

Will a bone marrow transplant change one's blood type?

Will a bone marrow transplant change one's blood type? Or is the donor blood type matched with the person before transplant?
5
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2answers
1k views

Why do we assume that the first humans were dark-skinned?

According to the article Dark skin and blue eyes: How Europeans once looked: It is widely accepted that Man's oldest common forefather was dark skinned, and that people became more pale as they ...
5
votes
1answer
180 views

Why are certain aneuploidies more common?

Certain aneuploidies such as trisomy-21 (Downs syndrome), trisomy-18 (Edward syndrome), Turner syndrome (XO) etc are more common than others. I had a vague thought that it is related to chromosome ...
5
votes
1answer
249 views

Would a spinal injury decrease human height?

A woman I know has been losing height at a rate of few cm a year following a severe spinal injury. How is this possible? What kind of injury could cause such progressive loss of height? Could this be ...
5
votes
1answer
179 views

What is a Mitochondrial Eve and Y-chromosomal Adam

I've read this question: What kind of event would cause the current Mitochondrial Eve to be replaced by a new one? And the values in Wikipedia about Mitochondrial Eve and Y-chromosomal Adam and I am ...
5
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1answer
168 views

Why is there no cure for Dandruff?

It looks like a simple problem, affecting almost half of the population at the post-pubertal age and of any gender and ethnicity [wikipedia]. What is so complex about finding a cure? Also, if you know ...
5
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1answer
43 views

Implications of what the discovery of Naia means

Recently a discovery was made of a ~12,000 year old girl in Hoyo Negro in Mexico. This has been covered by many different news agencies. I'm confused however by many of the reports. Does it ...
4
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2answers
200 views

The gender of offspring of Twins?

Given identical twin males, Michael and Douglas, Douglas and his wife have four children, all of whom are girls. Michael and his wife have only one child, a boy, and are expecting another. What are ...
4
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2answers
358 views

Why doesn't the human skin grow back exactly how it was before being damaged?

Very simple: Why (and how) is regenerated skin different from original ? As we know we lose skin cells that becomes the dust in out homes and it always grows back to full thickness right ? So when I ...
4
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1answer
288 views

Can humans shorten their sleeping patterns?

Can sleeping patterns be trained, or are they genetic? I read that a human needs to sleep at least 4 hours. Can sleeping time be reduced without having a negative impact?
4
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1answer
49 views

Why are irises unique?

I heard that irises are different and unique for every person. According this link, probability of two irises having identical pattern is 1 in 10 to the 78th power. That's how iris scanners identify ...
4
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1answer
941 views

Is ovum + ovum fertilization possible for human?

In humans is it possible to fertilize a ovum with another ovum from the same female subject? I already found some works in which the ovum is fertilized by a somatic cell (see e.g. this ), but I am ...
4
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1answer
125 views

Why isn't RH disease present in other mammals?

Basically, I have read about RH disease, Its rare but it can happen when an RH + baby is conceived by an RH - mother. This raises many questions. I have heard this problem only happens with humans, ...
3
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2answers
484 views

Initial population when i count backwards?

My question is dealing with how many ancestors it took to produce me: --> to produce me it took 2 people (my parents) = ($2^1$) people = 2 --> one generation further included = ($2^1 + 2^2$) people ...
3
votes
3answers
142 views

Why has grey hair evolved?

A vast majority of humans get at least some grey hair as they age. As far as I know this applies to both genders and all races. Presumably this means that at least some grey haired humans have ...
3
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1answer
334 views

What hair color will result in someone inheriting both blond and ginger genes?

Both the genes for blond hair and ginger hair are recessive, so they need both parents to give the same gene for it to take affect. What happens when a person has 1 copy of a recessive gene and ...
3
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1answer
88 views

Why did humans lose their fur?

The little amount of body hair humans have don't seem to be of much use for keeping warm. Our Simian cousins on the other hand sport thick furs. At which point during the species evolution and why ...
3
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3answers
369 views

What is the difference between eugenics and evolution by natural selection?

So with the working definition of Eugenics: "the aim to improve the human gene pool". What are key features that distinguish Eugenics from evolution by natural selection? I mean, besides that natural ...
3
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1answer
617 views

Why are men stronger than women?

What are the evolutionary explanations for why women are weaker than men (on average), and is this difference adaptive? See figure one here. I suppose that something puts pressure on men to be ...
3
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2answers
148 views

How does Humira work when injected into patients with rheumatoid arthritis?

OK, I have rheumatoid arthritis and I've been injecting Humira 2 times a month for the last 8 months. As far as I know rheumatoid arthritis is simply an immune system disorder which makes the immune ...
3
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1answer
25 views

Is there a realistic “family tree” model for the human population?

I would like to do some gene inheritance simulations, and I was wondering if there is an accepted model for what mating looks like in the general human population? I am not necessarily looking for the ...
3
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1answer
262 views

What factors govern the variable age of onset in Huntington's Disease?

"Huntington's disease (HD) is a neurodegenerative genetic disorder that affects muscle coordination and leads to cognitive decline and psychiatric problems." As we all know, this genetic disease ...
3
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1answer
87 views

Predictable microchimerism

I read in New Scientist recently that microchimerism occurs between previously born siblings and grandparents, not just the mother. Do we know which parts of the genome are likely to be transferred? ...
3
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2answers
129 views

Is there some genetic variance underlying music appreciation?

Is there any research done on the genetic variance for Music appreciation? If not, why is there no genetic variance for this trait?
3
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1answer
81 views

Regeneration capabilities in humans?

To what extent can humans, (mammals in general), theoretically regenerate, and is their a way to speed up and/or exceed this original extent.
2
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1answer
149 views

Is it really detrimental to humans as a species to reproduce with one's own first cousin?

Tired of hearing of these urban legends and popular opinions, I ask this question here to see if there really is scientific merit to this belief. My questions is, is it really "harmful" for a person ...
2
votes
2answers
761 views

Are human males and females more genetically different than members of other species?

I'm looking at this Ted talk about a Saudi Arabia woman who dared to drive a car in the last few years. This reminds me that until the last century or so, women (all over the world?) enjoyed less ...
2
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2answers
149 views

Is better healthcare a bane to the long-term survival of the human race?

The theory of natural selection has it that individuals with better genes tend to survive and reproduce, passing their genes to their offspring. This gradual process results in a population more ...
2
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4answers
297 views

How come most animals never seem to evolve over millenia?

People often say, including those with extensive knowledge in biology, that a certain species of animal will evolve in one way or another: 1.From changing environments. 2.Mutations. 3.Possibly even ...
2
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2answers
117 views

Like other animals, why humans don't have species & breeds?

Like other animals, why don't humans have species & breeds ? Even my pet dog is one type of breed, but we (humans) lack breeds & species? What is the main reason?
2
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1answer
101 views

What is the evolutionary cause for various finger lengths?

Why are the lengths the way they are with middle finger the longest?
2
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1answer
185 views

Is tongue rolling genetic?

Is the ability to roll your tongue or not truly inherited or genetic? What I have gathered from school has been contradicting with evidence I found elsewhere.