A broad group of consisting of biomolecules that are soluble in non-polar solvents. Most of these molecules have huge hydrocarbon chains (linear or cyclic). Examples include glycerides (glyceryl esters), isoprenoids and steroids.

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Synthesis of Fatty Acids Longer than 16 Carbons

I understand that the human body when performing Fatty Acid Synthesis can synthesize only until C16 (palmitate). However the ER has desaturases and elongases. I know that desaturases are used to add ...
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What is the actual function of HDLs and CETP?

I know that HDLs collect cholesterol from peripheral tissues and transport it back to the liver using SRB1 - Reverse cholesterol transport and dumping it in bile. So the tissue is producing some extra ...
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Lifeforms concentrations of the categories of macromolecules, and Lipids

Lifeforms are formed of large, modular, organic molecules called macromolecules, large organic molecules called Lipids, and simpler molecules such as H2O. Macromolecules are commonly grouped into the ...
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Is there a way to quantify in vivo cholesterol transport rates?

I have always had trouble grasping the physiology of lipoprotein cholesterol transport. The "standard" description found in the literature is that liver synthesizes cholesterol which is carried in ...
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Is it possible to measure in vivo enzyme kinetics?

I was wondering is there way in which we can measure enzyme kinetics in vivo specifically for enzymes acting on lipid substrates (where substrate is restricted to 2D membrane as oppose to freely ...
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phospholipid alterations in breast cancer

I'm interested in designing some experiments to assess how altering fatty acid synthesis affects phospholipid synthesis/lipid profiles. I've come across papers using standard inhibitors of FAS like ...