Internal organ of vertebrate species which is important for a lot of biochemical functions including production of molecules, detoxification and production of glycogen.

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Metabolism priority in poisonings

Let's assume we have two toxins - one of which is routinely metabolized by the liver, and the other is new to the organism (consider for example alcohol in a heavy drinker and any other drug that is ...
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15 views

Is it possible to measure Secondary Bile Acid Kinetics?

Is it possible to measure secondary bile acid kinetic and flux measurements in vivo? Anyone have any experience with this sort of technique?
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117 views

How is ammonia removed from the colon?

“Lactulose is also used to reduce the amount of ammonia in the blood of patients with liver disease. It works by drawing ammonia from the blood into the colon where it is removed from the body.” ...
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If eating 100% fat 2 times more worth the energy I spend during the day, will I store body fat?

So in theory, insulin hormone is the one that tells the body "eat more. don't burn body fat". Alongside with glucose blood level regulation and turning excessive glucose into liver (which later goes ...
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45 views

Liver - Regeneration in Cirrhosis

Liver is the most resilient of the human organ (on par with or next to skin). A very interesting experiment on liver regeneration is here. Even if two-thirds of the liver is removed, the remaining ...
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443 views

Grapefruits and CYP3A4

Grapefruit juice contains furanocoumarins, which irreversibly inhibit CYP3A4. For this reason, when one is taking certain medications it is necessary to not eat grapefruits because the inhibition of ...
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133 views

Duplicity Vs. Singularity of Mammals Organs [closed]

Are there known evolutionary reasons why mammals contain 2 of some organs (such as lungs and kidneys) and only 1 of some (such as liver)?
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39 views

Do metastatic cells still have their parent's identity?

If a liver cancer, for example, gives metastases. Will metastatic cells still have liver identity? I mean, if we mark liver cells, will we see the cancer cells too? Thanks a lot!
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Question about what the liver does NOT do

Which of the following functions is NOT performed by the liver? a) Storage of vitamins and minerals b) converts glucose to glycogen c) converts toxins to harmless chemicals d) produces bile I chose ...
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Does scratched Teflon coated frying pans contain carcinogens which can cause cancer? [closed]

Is it true that using scratched Teflon-coated pans contain carcinogens, and if so, can they be consumed through the food cooked in them? E.g. The deadly toxins from non-stick frying pans
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75 views

Biology Analogy

In my book are given several paired analogies with me being asked to give reason for them. I could solve all of them except this: liver = thrifty house-keeper I mean, I do not understand why the ...
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58 views

What is inside IDL (intermediate density lipoproteïn)?

I am studying about the endogene lipidcycle in the human body and I know that VLDL (very low density lipoproteïn) is made in the liver and that it contains triglycerides and cholesterol from your food ...
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989 views

How do nutrients get to the cells they need to get to?

I understand the basics of digestion. I know that nutrients get absorbed by the microvilli, enter the bloodstream and travel to the liver but after all that, what is the biological mechanism that ...
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301 views

How does activation of adenylcyclase lead to increased cAMP and diarrhea?

I am trying find explanation for these mechanisms Tox plasmid -> exotoxin (enterotoxin) -> activation of adenylcyclase -> \up cAMP enterocytes -> release of H2O, electrolytes in gut lumen -> ...
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83 views

How does Acetaldehyde accelerate mitosis?

I read that one of the ways alcohol is carcinogenic is via accelerated mitosis due to acetaldehyde, I was wondering what pathway caused this acceleration?
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4k views

Which blood vessel carries the most impure blood?

There is a question in my Biology textbook: "Which blood vessel in the human body carries most impure blood after few hours of meal." The answer is given as Renal artery. But I think the ...
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395 views

Why is the liver the only internal organ of the human body to regrow?

Related to my earlier question, "How does the human liver regrow?", am curious as to why the liver is the only major organ that has this capability? Why is it that other major organs, such as the ...
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77 views

How does the human liver regrow?

I understand that there would have to be a portion of liver present to regrow from, so how much liver would the minimum to be able to regrow? By what mechanism does regrowth occur?
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111 views

Size of classical liver lobule across species

A classical liver lobule is made up of a central vein and the portal triads. A typical human liver weighs around 3 lbs. , while a typical bovine liver weighs around 12 lbs. I was wondering if anyone ...
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641 views

What metabolic activities are performed by a developing human fetus's liver?

I understand that organ function varies with the stages of development. Does a fetal liver EVER perform lipogenesis, gluconeogenesis, make bile, etc? Or does it only begin performing these actions ...
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106 views

Can cirrhosis be caused by physical compression of the body?

On a random forum, a member speculated that their cirrhosis was caused by wearing tight-fitting clothing such as a girdle or corset. This leads me to the following question: Question: Can ...
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993 views

Circulation through the liver in light of drug metabolism

I have a lingering question which stems from an answer that I gave to What hydrolyses aspirin within the digestive tract and blood stream? When a drug or any other substance is absorbed into the ...