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3
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0answers
32 views

What makes the amide bond the lowest energy pathway?

I've reading about proteomics and how it can be used with mass spectrometry to sequence digested peptides. Reading this paper the author states (in box 2): peptide fragmentation induced by ...
1
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39 views

Which mass spectrometry database search algorithms include the fragment mass accuracy in the calculation of protein scores?

E.g. in a MASCOT search, the accuracy of the fragment ions in a ms/ms spectrum does not have any influence on the scores of identified proteins (unless the fragment ions are out of the set ms/ms ...
1
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0answers
155 views

Mass change in deamidation from Glutamine to Glutamate

To detect the deamidation from Glutamine to Glutamate in a protein, normal practise seems to be a mass spec, where it is claimed there is a change of 1 dalton. EG It is claimed that: Deamidation ...