Theoretical models that explain a system using mathematical equations.
4
votes
1answer
106 views
Is local equilibrium a reasonable assumption for evolutionary processes?
Whenever I look at discussions of fitness landscapes (in particular, Kauffman's NK model) the questions tend to resemble:
The population is at a local equilibrium, but another equilibrium of ...
3
votes
1answer
61 views
Are there natural selection experiments that quantitatively agree with theoretical modeling?
Has anyone ever conducted an evolution experiment and quantitatively compared it to theory? For example, has anyone ever put bacteria in a million petri dishes filled with antibiotics and calculated ...
3
votes
1answer
53 views
When does weak selection produce qualitatively different results from strong selection?
In evolutionary game theory, it is typical to model organisms as having a base fitness that is modified slightly by the game interaction. The ratio of the game effect versus the base fitness ...
3
votes
0answers
38 views
Structure of fitness landscapes in the NK model
The NK model of rugged fitness landscapes consists of $N$ sites where fitness contribution of each site depends on its state $\{0,1\}$ and is epistatically affected by $K$ other sites. When defining ...
2
votes
0answers
41 views
What is the minimum population size that Hardy-Weinberg calculations can be applied to?
I'm trying to find out if a particular allele is in Hardy-Weinberg disequilibrium, but the data is poor. What's the minimum population number that you can use to get any sort of respectable ...
2
votes
0answers
40 views
Experimental techniques to measure protein-protein and protein-ligand structure and dynamics
We would like to compare our simulation results with experimentation. When one wants to follow experimentally the dynamics (and possibly structure) of protein-protein or protein-ligand docking ...
1
vote
0answers
15 views
Looking for detailed nutrient/energy flow at the bottom of the freshwater food chain
I am trying to model the production and consumption of nutrients and waste at the bottom of the food chain in freshwater ecosystems.
I can only find broad information on the Internet and don't know ...
1
vote
0answers
14 views
Range of feasible coefficients in an unlimited growth model
If you are given an unlimited growth model in the form:
dP(t)/dt = k P(t)
Obviously the population growth would never be unlimited, but let's presume for the ...
0
votes
0answers
3 views
Reverse complement of reconstruction model for assembling reads
One way to assemble fragments produced by DNA sequencing (often called reads) is to seek for the shortest common superstring that contains all the reads of a given set of reads. One model for this ...
