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16
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4answers
2k views

Where’s the flaw in my proposed TB Treatment?

Ten years ago, I emailed a prominent lung specialist with my suggestion for a treatment for Tuberculosis. His lack of response led me to believe that the idea had no merit whatsoever – but I had no ...
14
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1answer
27k views

how to close a severed artery/vein?

This is a medicine-related question that I've been wondering about. I've been watching medical lectures on YouTube regarding the human body and was wondering about how surgeons treat a severed artery ...
13
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1answer
163 views

Doing a medical study on yourself?

What research guidelines is a person legally mandated to follow if they want to do medical experimentation on themselves? There is a large amount of variation in the types of medical experiments so I ...
12
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1answer
187 views

Why do doctors still advise HIV+ couples to wear a condom during sex?

HIV infected people already have HIV, but why do doctors still advise condom use for HIV+ couples?
12
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3answers
4k views

What does irregular heartbeat mean in simple language?

I bought a blood pressure monitor (A&D UA-851) which has the option to measure irregular heartbeat. I do understand what 'irregular' means, but why do irregular heartbeats happen and what are it'...
12
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1answer
3k views

Do we actually get more sick (flu/cold) during winter?

The word flu derives from the Italian phrase "influenza de freddo" meaning "influence of the cold". Indeed it is that time of the year when my colleagues seem to have the flu/cold more often than not....
8
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2answers
1k views

What is the biological reason for a burst appendix being potentially lethal?

Given that the appendix does not seem to be used by the human body, what is the biological reason that it is potentially lethal when this organ bursts? Also, what would cause the 'burst'?
8
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2answers
2k views

How are Maggots Sterilized (Disinfected)?

For maggot therapy, how are maggots disinfected? I'd imagine there's a limited scope of measurements that can be taken to sterilize the maggots - i.e. we don't want to sterilize them and kill them too....
7
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2answers
256 views

Why does botulinum toxin seem to be more dangerous to humans than to other mammals?

Various mammals seem to get away with eating parts of carcasses that we would prefer to not even touch, and that we assume will make us sick. Because of that, I assume botulinum toxin is more ...
7
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1answer
129 views

Do animals get sick with hemorrhoids?

Do animals get sick with hemorrhoids ? And why Humans are most affected of it ? Is it because the gravity center of Humans is sittuated in the anal ?
6
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1answer
85 views

Why ml scale blood retrieval is required to run a blood test?

Substances found in blood are present at microscopic scale and tend to be invisible to the unaided eye. Why is a whole vial of blood (at ml scale) is required to assess the presence and concentration ...
6
votes
1answer
64 views

Are there medical treatments that were so effective they were never subjected to a randomized control trial?

I'm thinking of things like antibiotics for meningitis or tuberculosis, or thiamine for Wernicke-Korsakoff syndrome. In those cases the magnitude of the treatment effect might have been so great that ...
5
votes
2answers
582 views

Functions of the CFTR gene?

I am a senior in high school and I am studying cystic fibrosis. I don't quite get the function of the CFTR gene as this is my first time dealing with this type of heavy scientific info. I had ...
5
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3answers
1k views

How does vasoconstriction/vasodilation change blood pressure?

Background: I am coming at this question from an electrical engineering background, and I feel like I am missing certain assumptions that are going into the statement found in my physiology textbook, "...
5
votes
1answer
137 views

Formaldehyde turns plantar region of feet red?

I'm a freshman med student and I've noticed that on all the feet (and hands) of deceased people that I've worked with, the bottom of the feet always turns red and also the inside of the palm? Why is ...
5
votes
1answer
121 views

Could this Francobelgian comic book woman really have these 4 diseases at the same time?

I'm doing an archive binge of a paper comic "The Kiekeboes". One of the characters is an elderly woman currently at the doctor, and she says the has the following illnesses: Erythema Exsudativum ...
5
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1answer
100 views

Survival curve in early humans

The survival curve/function describes the probability of a given individual to survive to age $x$. In humans, today's survival function is very much influenced by medicine. This leads me to wonder ...
5
votes
2answers
259 views

Viruses: Adaptation to a new host through repeated host jumps

A friend told me, during a 3 minute discussion, that viruses that are endemic in host $A$ and make repeated jumps to host $B$ but can't be transmitted between individuals of species $B$, may slowly ...
5
votes
1answer
2k views

How does food intake affect medicine? Why pill instructions recommends taking them before (after) meal?

Even simple vitamins seem to have this in the instruction. Why is is so? Is there some simple model of how do pills interact with food? Does it depend on the food type? (What about drinks?) Should ...
5
votes
0answers
54 views

Do “scars” in humans replace all the skin layers or only some layers?

When someone has a cut or surgical incision that results in a "scar", is the scar tissue replacing all 3 layers of the skin (epidermis, dermis, hypodermis)? Or only the first one or two of them?
5
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0answers
73 views

Why do some medicines induce sleep? [closed]

I have seen lot of people sleep or say that they are feeling sleepy after taking some medicines. Why? I mean, if a medicine acts on some cell of the body because that cell has got its receptors and ...
4
votes
2answers
4k views

Is pork poisonous?

Besides religious prohibition, there are several non-religious arguments against eating pork. A few of which are: Pigs and swine are so poisonous that you can hardly kill them with strychnine or ...
4
votes
1answer
158 views

Why do people in the scientific community use terminology such as renal, hepatic, cardiac instead of kidney, liver and heart? [closed]

Are there differences between renal, hepatic, cardiac and kidney, liver and heart? Is the "jargon" used more commonly because of tradition, or is there some definitive biological basis to it?
4
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2answers
85 views

What is overdiagnosis?

What is overdiagnosis ? I have searched this Wiki result but didn't understood at all. Can you please explain the first two line of Wikipedia : Overdiagnosis is the diagnosis of "disease" that ...
4
votes
1answer
50 views

Where are newly discovered medicines tested

When a medicine is prepared by a biologist,then where does he first test on? And how does he know that this is the exact combination for a disease to get cured? Does he test that medicine on a human ...
4
votes
2answers
2k views

Do all Gram negative bacteria cause septic shock?

Do all Gram negative bacteria cause septic shock? If they don't could they if you attacked them with an antibiotic that could lyse the cell? For example any antibiotic that attacks the cell wall, ...
4
votes
1answer
71 views

Why can't we find a broad spectrum antiviral drug to viruses like antibiotics to bacteria?

Antibiotics have a very broad spectrum because they attack the metabolism pathways many bacteria share. For example, penicillin inhibits peptidoglycan synthesis, which is vital for formation of cell ...
4
votes
1answer
188 views

Miscarriage in early humans

Today, about 10 to 20 percent of known pregnancy end in miscarriage. Pregnancy is a biological process that has been very well studied by medicine. As a result, modern medicine helps a lot to prevent ...
4
votes
1answer
85 views

Why is the ebola virus so intense now?

So i'm looking into the ebola crisis and it seems the death toll is really getting crazy. I understand that it's a cytomegalovirus and that it basically overwhelms the immune system due to it's size ...
4
votes
2answers
99 views

Is there a standard reference for the importance of tumor heterogeneity?

In a recent post, Philip Gerlee highlighted the two biggest contributions of mathematical oncology to cancer research: (1) increasing focus on the progress of cancer as an evolutionary process, and (2)...
4
votes
1answer
76 views

What is the best way to orally administer a water insoluble powdered drug to macaque monkeys?

They typically need to be given ~150mg, once a day, and it'll last for two weeks. The drug is very water insoluble, becomes almost like a paste, not suitable for tube feeding. And yes, this is for for ...
4
votes
1answer
76 views

What evidence is there on the medical effects of circumcision?

If this is the wrong place to post this question, then I will delete it and post it were it belongs. I have heard many conflicting things about circumcision. I have heard that it reduces the rate of ...
4
votes
0answers
43 views

How does drug-induced photosensitivity work?

Some drugs (tetracyclines, for instance) can cause photosensitivity reactions—that is, some patients become extremely sensitive to the sun, developing rashes or inflammation after spending time ...
3
votes
3answers
237 views

Can/Have cancer cells be/been used in stem cell culture lines?

Since Cancer cells have unlimited growth potential, can they be induced towards totipotency and pluripotency? If so, can cancer cells be used in stem cell culture because of similar properties of ...
3
votes
2answers
68 views

Is half-a-tablet of X a substitute for a tablet of X/2?

This may be anecdotal. At the pharmacy earlier, the prescription called for a drug with X mg of the target chemical. The pharmacy however only had stock of a higher potency of the same brand. E.g. ...
3
votes
1answer
75 views

Is a bone marrow transplant limited by sex?

Can a female patient get transplanted with bone marrow of a male donor and vice versa?
3
votes
1answer
75 views

Why are pharmacology studies so experimental?

I am a med student, and as far as I see from our pharmacology lectures, pharmacologists work almost completely experimental. Quite typically they take a substance (e.g., from nature), they add, change ...
3
votes
1answer
60 views

What are the benefits of statins in terms of prolonging life?

Recently the UK government suggested that all adults over the age of 50, without exception, would benefit from taking statins. I have an elderly female relative who may, or may not have had a minor ...
3
votes
1answer
70 views

spinal cord lesion and result in somatic sensation

Jimbo suffers a lesion to the entire right half of the spinal cord at the T6 level. A few weeks after his injury, his doctor tests his right and left legs for somatic sensation and tone. fill out her ...
3
votes
1answer
8k views

Do Penicillin based antibiotics affect birth control?

I wasn't sure whether to ask this question on Biology or Chemistry Stack Exchange, since it is really biochemisty, but this is something that's been puzzling me. Most pharmacists (all that I've ...
3
votes
1answer
70 views

Gradual slowing breath, its effect on health

I've written a computer program which beeps, then beeps after 10 sec, then beeps after 11 sec, then beeps after 12 sec, etc. I tried the following "experiment" on myself: do only one breath between ...
3
votes
1answer
63 views

What are the longterm effects of pancreatitis?

As the title asks, what are the longterm effects of pancreatitis? Having one event, is the person more susceptible to have a recurrence, or are they at higher risk of other conditions such as ...
3
votes
0answers
17 views

How is the side-polarity of the myosin filament in myofibril maintained?

If myosin molecules are the properly oriented relative to their position in the the myosin filaments, the sarcomere is not functional. But how is the orientation of the myosin molecules determined? ...
3
votes
0answers
39 views

Why are kidney discard rates so high?

A recent report from UNOS states: The kidney discard rate has returned to pre-KAS levels, dropping from 20.2 percent in the first six months to 18.4 percent in months 7-10. To me, this seems ...
3
votes
0answers
54 views

Database of Medical Assertions

Can anyone point me toward a computationally-accessible database of medical assertions? I'm looking for something where each row in the database contains a single unit of knowledge. It could either be ...
2
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2answers
115 views

Why do people use anti-inflammatory drugs?

Why people should take anti-inflammatory drugs, when inflammation is a physiological way to defend our organism?
2
votes
2answers
113 views

Blood draw from the elderly or those with tiny veins

A lot of people have very small veins making it next to impossible to draw blood. Would a nitroglycerin tablet (or some other vasodilator) before drawing blood help to enlarge veins?
2
votes
1answer
71 views

Do oral vaccines exist?

Do edible vaccines exist, and if yes, what is their mode of action? Are there any edible vaccines commercially available now?
2
votes
3answers
92 views

Homeopathy is placebo, but isn't placebo good?

I never considered homeopathy as a serious and scientific medicine, and now we have plenty of evidence supporting this (http://www.theguardian.com/commentisfree/2015/mar/12/no-scientific-case-...
2
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2answers
61 views

Are we more/less resistant to infectious diseases during an allergic reaction?

To my understanding, an allergic response is a non-adaptive response of the immune system to some molecule. The molecule in question is therefore "thought by the immune system" to be infectious ...