0
votes
0answers
38 views

Poly Unsaturated Fatty Acid

PUFAs spontaneously oxidize, speed up the process of glycation, since too much glucose and they also decrease mitochondrial respiration - more oxygen and CO2, less lactate and PUFA also promote ...
2
votes
1answer
41 views

naturally occuring fatty acids

The double bonds in naturally occurring fatty acids present in our body are in cis configuration while the enzymes for beta oxidation can act on trans double bond. Then what will be the significance ...
-1
votes
1answer
63 views

What organism most efficiently converts a given quantity of mass into heat?

Question I am trying to answer: In the popular film The Matrix, heat given off by humans is harvested as an energy source. I wondered, if this were possible, would humans be a good organism to ...
1
vote
0answers
52 views

amino acid containing branched side chain

Branched-chain amino acid are degraded by branched chain alpha-keto acid dehydrogenase complex. These amino acids aren't degraded in liver because of the absence of this enzyme(in liver).Why the ...
3
votes
1answer
22 views

bacterial cell wall degradation in humans

can human degrade the D-amino acid present in bacterial cell wall, I'm confused about it i have read somewhere that human can do so.If yes than why we need antibiotic to kill bacteria???If it is not ...
2
votes
1answer
63 views

Anaerobic respiration choice in E. coli

Under anaerobic conditions E. coli has two options to generate ATP: fermentation (substrate-level phosphorylation), and respiration (proton gradient, chemisomotic phosphorylation). Which is favored? ...
0
votes
1answer
28 views

Feedback affecting myocyte metabolism in humans

I understand that there are several reserves available to muscle that can be tapped for ATP, and that each reserve is being used to some degree at all times. Are these reaction rates purely due to ...
4
votes
2answers
99 views

Why isn't the phosphoglycerate kinase reaction of the glycolysis pathway irreversible?

Step 7 of the glycolysis pathway is the conversion of 1,3-bisphosphoglycerate into 3-phosphoglycerate by the action of the enzyme phosphoglycerate kinase, resulting in the production of 2 ATP ...
5
votes
2answers
125 views

What is an irreversible reaction?

There are reactions with large Delta G negative values. Why these reactions are irreversible? As in: out of 10 steps of Glycolysis, 3 are irreversible steps. I need an explanation for why they are ...
3
votes
2answers
58 views

Why do humans circulate monosaccharides instead of disaccharides as in plants?

Plants transport food mostly in the form of disaccharides like sucrose but humans transport them in the form of a monosaccharide - glucose. What is the reason behind this ?
6
votes
1answer
87 views

What are the lifetimes of cellular components on organelle or molecular level?

I was thinking that even though I know how generally the cell works, I don't really have a feeling of how volatile it is. I want to know what is the lifetime/turnover rate of different constituents of ...
2
votes
0answers
62 views

How is Energy Generated in Cats?

I recall reading that much of the energy a cat produces from its food comes from proteins which I assume would produce energy via being catabolised into amino acids which in turn, if glucogenic, would ...
1
vote
0answers
53 views

Why is a nicotinamide-tryptophan combination used to treat affective episodes in a few older clinical trials?

At least one of the journal articles that reported on such clinical trials allured to the nicotinamide-tryptophan pathway that I assume must be related to the metabolism of tryptophan into serotonin ...
0
votes
0answers
46 views

Where can I find complete description of the nucleotide biosynthesis?

I'm looking for a good source for learning nucleotide biosynthesis pathway (including enzymes and possibly also structural formulas) - what is the best source I could find such pathway, presented in a ...
1
vote
1answer
52 views

Isoprenoid Diphosphate Concentration in Yeast saccharomyces cerevisiae

Isoprenoid Diphosphate(IPP) is an important metabolites which is precursor in lot of secondary metabolites like Dolichol diphosphate, ubiquinone, prenylated proteins and carotenoid (not synthesized ...
0
votes
0answers
96 views

How do cells slowly degrade 5,5'-dibromo-4,4'-dichloro-indigo?

5,5'-dibromo-4,4'-dichloro-indigo is the product of X-gal cleavage, often used as a reporter with B-galactosidase. I've made the (unreferenced) observation that it seems as though the blue product ...
4
votes
1answer
224 views

What is the molecular basis of hangovers?

Well, most of us have experienced the wonderful feeling of the dreaded hangover. How does it work exactly? I imagine it has something to do with dehydration but what are the underlying mechanisms? ...
4
votes
1answer
4k views

Does mixing alcoholic drinks really make you more drunk?

There is plenty of anecdotal evidence ("beer after wine and you'll feel fine, wine after beer will make you feel queer") that mixing alcoholic drink types leads to a stronger effect, but I can't find ...
5
votes
1answer
80 views

In which way would the yeast cell cope with the excess amount of methionine in the growth media?

I guess that when there is surplus of methionine in the cell it is incorporated in the TCA cycle as a succinyl CoA, with cysteine as a by-product. But now the cell has the surplus of cysteine. What ...
4
votes
1answer
254 views

Are there any intersections between the biochemical pathways of uracil biosynthesis (or metabolism) and methionine degradation in eukaryotes?

Is there any way in which uracil biosynthesis or metabolism could help cell in degradation of toxic levels of methionine?
8
votes
3answers
10k views

Why can't the brain and red blood cells use fuels other than glucose?

The question is rather straight forward: I have always been curious as to why, but cannot find an explanation online. I can imagine that the mechanism is different for each, but why does brain tissue ...
15
votes
2answers
3k views

Why is glucose our primary source of energy?

Is there any evolutionary reason for glucose being the "main" molecule used as a source of energy, beginning with glycolysis and subsequently cellular respiration (after being converted to two ...
3
votes
1answer
148 views

Negative feedback in the fructose metabolism in liver

What happens in liver when large amount of fructose is consumed? I vaguely remember my biochemistry lecturer telling us that the enzymes that process fructose in the liver does not have negative ...
8
votes
1answer
232 views

How Antioxidants affects Human Metabolism?

I'd like to know how antioxidants affects the human metabolism and which ones are essential for metabolism processes.
11
votes
3answers
1k views

What happens to dextrorotatory amino acids in humans?

As indicated by this question, most of the amino acids in the human body have the L-chirality. As enzymes also have handedness, what happens to the D-amino acids that end up within the human body? Are ...
12
votes
3answers
26k views

What is a coupled reaction and why do cells couple reactions?

I was wondering what exactly a coupled reaction is and why cells couple them. I read the wikipedia article as well as several others, such as life.illinois.edu but I still don't get it. Could ...
7
votes
2answers
200 views

During famine, does the human body do anything to prioritize which organs receive nutrients?

When food is scarce, the body slows its metabolism. Are there any other systems or processes that encourage prioritization of organs?
8
votes
1answer
217 views

What are the biochemical processes occurring when food spoils?

Let's assume for a minute that microbes themselves and their direct toxic products (i.e. endotoxins) aren't toxic to humans. Let's also discount any innate immune responses the body mounts against the ...
16
votes
1answer
653 views

ATP cost for gene expression

How would you estimate the number of ATPs required to transcribe, export and translate a single eukariotic protein?
7
votes
2answers
322 views

Can a living organism run on electricity?

Each time I'm too lazy too cook I think it'd be cool to be able to just plug myselt into an outlet. Yet I know it is not possible - I need amino acids and a lot of other stuff that electricity can't ...