The set of chemical reactions that happen in the cells of living organisms to sustain life.

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Is body energy production and consumption cyclical?

If we look into how energy is produced by the humans, it always involves some kind of periodicity: fuel combustion rotates engines, water rotates turbines, nuclear chain reactions heat up water, which ...
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1answer
44 views

How does the human body use energy?

As far as I know the glucose gets processed from carbs and fats and as a result carbon dioxide, water and "energy" are released. The carbon dioxide and water are expelled by the body, and then energy ...
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2answers
810 views

What is an irreversible reaction?

There are reactions with large Delta G negative values. Why these reactions are irreversible? As in: out of 10 steps of Glycolysis, 3 are irreversible steps. I need an explanation for why they are ...
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1answer
127 views

How efficient is the human body at metabolizing food?

My friend and I were having a discussion over how "efficient" human digestion is. If a human ate a 1000 calorie hamburger, how many of those calories (how much energy) does the body process into ...
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53 views

Oxidation means inflamation?

All right, I was reading article on nutrition, that focussed on content analysis of pastry-like food product for kids. I have to say that I am not sure this article would pass the imaginary smell ...
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4answers
4k views

Why do we weigh less in the morning?

At first I thought it may be related to physics. You know, in one half of the day, the gravity changes, and the scale shows a different weight than the other. Then at night, gravity intensifies, and ...
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1answer
8k views

Why is my faeces black in color after eating Oreos

Why is my faeces black in colour the morning after I eat some Oreos? Day 1 : Eat a handful of Oreos & the next morning your stool is black. Day 3 : Eat a handful of cocoa flavored biscuits & ...
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1answer
117 views

The smell from eating asparagus

I am wondering about one thing. I have read different accounts of this (prior to reading it on Wikipedia), so I am wondering. Here are the two versions I have read: asparagus leads in a certain ...
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1answer
97 views

Consumption of NAD+ in glycolysis

Out of 10 steps in glycolysis, only one reaction- Glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (PGP), uses NAD+ and thereby producing NADH. Furthermore, this very step is solely ...
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1k views

In Japan, the official average body temperature is 36.0 °C. Why so different from that of Europe?

The Japanese Wikipedia states that the average human body temperature is 36.0 °C (here,"ヒト"). The statement references the data from the Japanese government. Actually all of my Japanese friends think ...
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1answer
961 views

Why our body does not produce polyunsaturated fatty acids?

Our body does not produce two polyunsaturated fatty acids (PUFA): linoleic acid and alfa-linolenic acid. I am thinking reasons for it. Saturated fatty acids have more energy than unsaturated. ...
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59 views

naturally occuring fatty acids

The double bonds in naturally occurring fatty acids present in our body are in cis configuration while the enzymes for beta oxidation can act on trans double bond. Then what will be the significance ...
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1answer
89 views

What organism most efficiently converts a given quantity of mass into heat?

Question I am trying to answer: In the popular film The Matrix, heat given off by humans is harvested as an energy source. I wondered, if this were possible, would humans be a good organism to ...
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1answer
136 views

Why doesn't Diabetes cause death by starvation?

The main cause for diabetes is lack of insulin in the body. Insulin is the hormone that allows body cells to absorb glucose from the blood. With out insulin, the body cells can't get glucose from the ...
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1answer
36 views

bacterial cell wall degradation in humans

can human degrade the D-amino acid present in bacterial cell wall, I'm confused about it i have read somewhere that human can do so.If yes than why we need antibiotic to kill bacteria???If it is not ...
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2answers
97 views

Where can I find a list of common enzyme cofactors and/or co-enzymes?

Where can I find a list of enzyme cofactors and/or co-enzymes, ordered by how common they are? For example, $O_2$, $H_2O$, $ATP$, $ADP$, $NAD$, should be ranked in the first places, because they ...
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1answer
155 views

what is the margarine metabolism in our body?

margarine is commonly used food ingredients that contribute to both inflammation and obesity , but actually I want to know the margarine metabolism in the human body I can find some resources talk ...
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22 views

desaturation in fatty acids [duplicate]

humans are unable to synthesize EFA what is the reason behind it that humans cannot introduce double bond between C-10 and the methyl terminal?
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1answer
153 views

How should I feed and keep an ant queen?

I have captured wandering ant queen. I guess she was just fertilised and was looking for a place to start a hive. I'd like to create my own ant hive in artificial environment. I unfortunately only ...
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66 views

Why Mammals are unable to produce Essential Fatty Acids?

While we have to get them from our diet and if they aren't taken in our diet we will face disease.Then why we don't have the enzymes which are require for EFA synthesis???
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1answer
49 views

Currency metabolites vs. current metabolites: What's the right term?

I have seen the two terms currency metabolite and current metabolite used interchangeably. Is there a consensus on which is the ...
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1answer
89 views

Do mitochondria use ATP in order make another ATP from glucose?

Do mitochondria use ATP in order make another ATP from glucose, or does it use another source of energy to convert glucose to ATP?
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1answer
131 views

What are the lifetimes of cellular components on organelle or molecular level?

I was thinking that even though I know how generally the cell works, I don't really have a feeling of how volatile it is. I want to know what is the lifetime/turnover rate of different constituents of ...
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1answer
63 views

Why is duck fat less saturated than cow fat?

Why does the composition of fat in animals vary? Is there an evolutionary advantage to producing fat that is less or more saturated?
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1answer
239 views

Anaerobic respiration choice in E. coli

Under anaerobic conditions E. coli has two options to generate ATP: fermentation (substrate-level phosphorylation), and respiration (proton gradient, chemisomotic phosphorylation). Which is favored? ...
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1answer
298 views

What marine animals exhibit deep hibernation/aestivation?

Do marine animals exhibit deep hibernation/aestivation as land-based creatures do? If not, Why?
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1answer
72 views

Selective Androgen Receptor Agonist

I'm looking for an inducer that strongly activates the androgen receptor, but not the glucocorticoid receptor that is not DEA regulated. I know that SARMS (Selective Androgen Receptor Modulators) are ...
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1answer
39 views

Feedback affecting myocyte metabolism in humans

I understand that there are several reserves available to muscle that can be tapped for ATP, and that each reserve is being used to some degree at all times. Are these reaction rates purely due to ...
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55 views

Regulation of Cra protein level in E coli

Catabolite Activator/Repressor, Cra protein (formerly known as Fructure Repressor FruR) plays a significant role in central carbon metabolism of E coli. Its activity is inhibited by ...
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2answers
104 views

Why isn't phosphorus or nitrogen a limiting nutrient for animals?

Nitrogen and Phosphorus are usually the limiting nutrient for plants, especially for algae. Phosphorus is used for DNA, ATP and phospholipids, and Nitrogen is used for pretty much every protein a ...
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2answers
317 views

Can animals make their own unsaturated fatty acids?

I know that animals can't make poly-unsaturated fatty acids (PUFA) and so require them from dietary sources. For eg.Omega -3 and Omega 6 fatty acids. My questions : Can animals synthesize other ...
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1answer
66 views

Could the Warburg effect be used to starve cancer cells in situ?

What is wrong with the following chain of reasoning? Nearly all cancer cells rely on high rates of glucose uptake (upto 200 times more than normal cells). This is known as the the Warburg effect. ...
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500 views

Why isn't the phosphoglycerate kinase reaction of the glycolysis pathway irreversible?

Step 7 of the glycolysis pathway is the conversion of 1,3-bisphosphoglycerate into 3-phosphoglycerate by the action of the enzyme phosphoglycerate kinase, resulting in the production of 2 ATP ...
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1answer
75 views

What is the energy consumption of the brain?

What is the energy consumption of the brain, and is there a difference in consumption when waking and sleeping?
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1answer
124 views

How do Gram + bacteria use a proton gradient for F-type ATPase?

Does anyone know of any papers showing how Gram positive Fermiculates or Actinobacteria use a H+ gradient for an F-type ATPase, It seems impossible since there is no outer LPS membrane to maintain ...
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2k views

Do any organisms recycle their own waste internally?

I thought of this question yesterday and it turns out it's surprisingly hard to Google.
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281 views

carbohydrates and lipids as a source of energy? why?

Why carbohydrates and lipids basically used as a sources of energy? Why only proteins are used as building blocks of all the creations? Yes there are some parts of cells like cell walls in which ...
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3answers
509 views

Are all body atoms really recycled several times during a life?

I heard a point, that all (human) body atoms are recycled withing short period like few years. Recycled means "old" atoms are replaced by "new" ones during metabolism, leaving only structure ...
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1answer
65 views

How much solar energy required to compensate food?

Just curious, how much solar energy can power an (herbivore) animal? Specifically, is it enough sunlight on Mercury (4 to 10 times brighter than on Earth) to "feed" a zebra? Will it be sufficient at ...
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1answer
58 views

Is it easier to burn a calorie of fat or a calorie of a carbohydrate?

Say someone eats 100 calories of chocolate vs. 100 calories of carrots. Something tells me that eating the chocolate will lead to you generating more fat. Will it? Is it harder to burn the calories ...
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1answer
120 views

What constitutes the determination of a normal blood glucose level?

Several on-line resources (e.g. MedlinePlus) suggest: Normal range for non-diabetic people who are fasting should range between: 70 and 100 milligrams per deciliter (mg/dL) Non-diabetic people who ...
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2answers
88 views

Why do humans circulate monosaccharides instead of disaccharides as in plants?

Plants transport food mostly in the form of disaccharides like sucrose but humans transport them in the form of a monosaccharide - glucose. What is the reason behind this ?
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122 views

How to relate human metabolic model reactions and cancer drug targets / reactome items?

Trying to find a way to take a cancer drug (from CancerDR, for instance) and infer the metabolic reactions that are affected by it in the Human Metabolic Model. Essentially, I would like to know ...
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1answer
77 views

How usable is the Human Metabolic Model to predict biomass?

In order to use the Human Metabolic Model for Flux Balance Analysis of specific cancer cell lines, we would like to know what sort of flux values have been determined for the Human Metabolic Model. ...
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1answer
36 views

What are good data on the Human Metabolic Model and where can I get them?

Trying to get a good SBML representation of the Human Metabolic Model for use in Flux Balance Analysis and drug targetting (i.e. gene knockout) simulations. What are good sources for these data? ...
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1answer
76 views

Where can I find the metabolic network for the human erythrocyte?

Where can I find the metabolic network of the human erythrocyte (red blood cell), in SBML format? The red blood cell metabolic network is a model that's usually employed in the literature [see refs ...
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2answers
196 views

How to determine the actual flux in the human metabolic model of a cell line?

The problem to be solved is to determine what the flux values are for the different reactions in the human metabolic model. As far as I understand, a good way to do that would be to use gene ...
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1answer
62 views

Isoprenoid Diphosphate Concentration in Yeast saccharomyces cerevisiae

Isoprenoid Diphosphate(IPP) is an important metabolites which is precursor in lot of secondary metabolites like Dolichol diphosphate, ubiquinone, prenylated proteins and carotenoid (not synthesized ...
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3answers
166 views

Assay for Beta-galactosidase activity in single cell microscopy

I'd like to be able to measure the activity of $\beta$-galactosidase in living cells with simple optical (maybe fluorescence) microscopy. Ideally I'd like to do a minimum of genetic engineering, and ...
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1answer
217 views

Why does beta-2-Thienylalanine inhibit bacterial growth?

I'm trying to obtain a better understanding of the Guthrie Test, which checks whether people have a disease called PKU. The Guthrie test uses bacteria to check for Phenylalanine (the amino acid) in ...