The set of biochemical reactions that sustain life by directly or indirectly affecting energy expenditure and/or storage, as well as the complete regulation of those reactions and the enzymes that catalyze them; including, hormonal, cell-signaling, and substrate level regulation.

learn more… | top users | synonyms

7
votes
1answer
133 views

If so many different hormones/molecules work by activating adenylyl cyclase, how do they have different effects?

It seems that many hormones and molecules work by activating adenylyl cyclase to convert $\text{ATP}$ to $\text{cAMP}$, such as adrenaline and glucagon. Both of these seem to bind to $\text G$ protein ...
7
votes
1answer
140 views

What mechanisms tell temperate trees when to drop leaves?

I've been looking around and cannot find a definite answer on what it is that tells trees to change their metabolism and drop leaves. I see that such activity is called Deciduous. What interests me ...
6
votes
2answers
261 views

Is there such thing as a generic “metabolic type”?

A while ago I picked up a book called "Eat right for your metabolic type". The book discussed the effects of the endocrine system on the overall shape and the speed of metabolism. The book outlined ...
6
votes
1answer
428 views

What is the molecular basis of hangovers?

Well, most of us have experienced the wonderful feeling of the dreaded hangover. How does it work exactly? I imagine it has something to do with dehydration but what are the underlying mechanisms? ...
6
votes
1answer
243 views

iodine: how did they manage without it in old ages? (People who were living far from the sea)

Knowing that today iodine comes either from fish products or (artificially) enriched table salt, how did people who lived far from the sea survive before (especially during the the Middle Ages)? Edit ...
6
votes
1answer
175 views

Cooking with sawdust

In a book about post-war Japan (Embracing Defeat, Dower) the author mentions a process for making sawdust at least partially edible, so it could be used in recipes in a 1:4 ratio with flour for ...
6
votes
2answers
395 views

How efficient is the human body at metabolizing food?

My friend and I were having a discussion over how "efficient" human digestion is. If a human ate a 1000 calorie hamburger, how many of those calories (how much energy) does the body process into ...
6
votes
2answers
271 views

At any given moment, how much energy is stored in the human body as ATP?

At any given moment, approximately how much energy is stored in the human body as ATP in the ADP-P-bond? This of course depends on what type of cell it is and the activity of the individual in ...
6
votes
2answers
72 views

Predicting and identifying microbes and enzymes DNA sequence with metabolic prediction

Presently I am working on metagenomics of coal biomethenation by bacterial consortium. I have got the sequence result (Illumina). The sequence is huge and I can't predict anything from the sequence. ...
5
votes
4answers
3k views

Is lemon water an alkalizing agent in the body?

I was recently having a discussion with someone about whether lemon water actually increases the pH of your body (by which I assume they mean the blood); their claim was that once Citric acid was ...
5
votes
2answers
330 views

Energy use by muscles, actual work done by muscles and more

Lately, I've started exercising in the gym and outside. I've also started to look at the details of food I eat. Food usually has a label saying the amount of energy is inside it. For example, some ...
5
votes
1answer
662 views

Why does muscle tissue have relatively constant AMP + ADP + AMP?

I was going over slides of energy expenditure in muscle cells. It mentions that in muscle tissue, the cell's energy charge ([ATP] / [AMP]) is the principle factor controlling glycolytic activity, and ...
5
votes
2answers
228 views

Energy released during the production of ATP?

When glucose is used during aerobic and anaerobic exercise, how much energy is expended or required? During aerobic exercise: $C_6H_{12}O_6 + 6 O_2 \to ATP + H_2O + 6 CO_2$ + energy During ...
5
votes
2answers
153 views

Burning fat transferred from one part of the body to another

While doing some research on cosmetic surgery, I discovered that there are several ways of doing breast enhancements, one of which was using body fat. While I haven't researched this method, I assume ...
5
votes
1answer
20k views

Why is my faeces black in color after eating Oreos

Why is my faeces black in colour the morning after I eat some Oreos? Day 1 : Eat a handful of Oreos & the next morning your stool is black. Day 3 : Eat a handful of cocoa flavored biscuits & ...
5
votes
1answer
69 views

How are ions 'pumped' across a membrane during electron transport?

A number of sites (including this one) that provide descriptions of photosynthesis state that high energy electrons 'pump' ions across a membrane. What is the actual 'pumping' mechanism? I've looked ...
5
votes
1answer
141 views

How to measure metabolic rates of microscopically small animals?

I want to measure metabolism rates in Tardigrades Metabolic rates will be assessed immediately following their exit from cryptobiosis (an animal dormant state). I know that oxygen levels is the ...
5
votes
1answer
2k views

Why our body does not produce polyunsaturated fatty acids?

Our body does not produce two polyunsaturated fatty acids (PUFA): linoleic acid and alfa-linolenic acid. I am thinking reasons for it. Saturated fatty acids have more energy than unsaturated. ...
5
votes
1answer
106 views

In which way would the yeast cell cope with the excess amount of methionine in the growth media?

I guess that when there is surplus of methionine in the cell it is incorporated in the TCA cycle as a succinyl CoA, with cysteine as a by-product. But now the cell has the surplus of cysteine. What ...
5
votes
1answer
2k views

What does vitamin B6 and B12 absorption depend upon?

I'm looking at my question about homocysteine metabolism and am doing a followup inquiry into vitamins B6(Pyroxidine) and B12(Cyanocobalamin). I've found this interesting bit about vitamin B12 and am ...
5
votes
1answer
189 views

What biological systems are affected by Vitamin B6 (or B vitamins in general)?

B vitamins and particularly the B6 vitamin appears to the one of the main ingredients in energy drinks. There has been anecdotal evidence from people interested in dreaming that ingestion of vitamin ...
5
votes
1answer
113 views

How does the body “know” how to metabolize foreign substances

As a freshman biochemistry major, I find myself befuddled by our body's ability to perform complex chemical reactions to break down foreign substances. I can see how we would evolve explicit pathways ...
5
votes
1answer
134 views

Selective Androgen Receptor Agonist

I'm looking for an inducer that strongly activates the androgen receptor, but not the glucocorticoid receptor that is not DEA regulated. I know that SARMS (Selective Androgen Receptor Modulators) are ...
5
votes
1answer
195 views

What effect do oligosaccharides, like those found in legumes, have on the composition of intestinal flora in humans and if so how so?

I know that intestinal flora metabolising oligosaccharides, like those found in legumes, is the cause for the well known fact that legumes cause flatulence, but does an oligosaccharide-rich intestine ...
5
votes
1answer
565 views

What is the biological mechanism underlying caffeine intolerance? (CYP1A2 or other?)

As far as I can tell, caffeine metabolism occurs primarily via the CYP1A2 enzyme. I am curious as to whether mutations in the CYP1A2 gene are associated with caffeine intolerance. Some site that is ...
5
votes
0answers
52 views

Is high metabolism linked to high evolutionary turnover?

I recently read The Dinosaur Heresies by Robert T. Bakker, a 1986 popular science book presenting arguments for an active lifestyle and high metabolic rate in dinosaurs. One of the arguments that ...
4
votes
3answers
2k views

What is the mechanism of oxygen uptake in E. coli?

How does E. coli uptake oxygen? Most of the literature I found is concerned with response to oxygen level supplied in the medium, as opposed to how much is actually transported inside. Can they shut ...
4
votes
2answers
320 views

Breakdown of energy expenditure at the level of a single cell

The metabolic rate measures how much energy an organism expends over a unit of time. Its breakdown for the human body in terms of its functions is well documented : so much for the heart, for the ...
4
votes
2answers
581 views

Where can I find a list of common enzyme cofactors and/or co-enzymes?

Where can I find a list of enzyme cofactors and/or co-enzymes, ordered by how common they are? For example, $O_2$, $H_2O$, $ATP$, $ADP$, $NAD$, should be ranked in the first places, because they ...
4
votes
2answers
99 views

How does it make thermodynamic sense for photosynthesizers to turn CO₂ into O₂?

My understanding is that animal metabolism consists of exothermic reactions like $$\ce{C6H12O6 + 6 O2 ->6 CO2 + 6 H2O + energy}$$ This makes thermodynamic sense to me. Animals need an exothermic ...
4
votes
2answers
548 views

Can animals make their own unsaturated fatty acids?

I know that animals can't make poly-unsaturated fatty acids (PUFA) and so require them from dietary sources. For eg.Omega -3 and Omega 6 fatty acids. My questions : Can animals synthesize other ...
4
votes
2answers
114 views

What's the point of glycolysis in fermentation?

In order to initiate glycolysis, 2 ATP are necessary. In the glycolytic process, you generate an additional 4 ATP, which results in a net gain of 2 ATP. If you don't undergo glycolysis, however, then ...
4
votes
2answers
6k views

Is there an evolutionary reason for the 5 electron transport complexes in plants and animals?

The electron transport chains of both the light reactions of photosynthesis (in plants) and oxidative phosphorylation (in animals) both contain 5 complexes including ATP synthase, as shown below. ...
4
votes
1answer
1k views

When is the lactase in lactose-free milk active?

Recently we have started suspecting that one of our children has hypolactasia (lactose intolerance), and so accordingly I have had my first exposure to lactose-free dairy- and dairy-like products. In ...
4
votes
1answer
584 views

Do effects of caffeine on human body change with habitual use?

I've been reading about homeostatic nature of a lot of neurobiological processes - the brain is trying to maintain a balance by desensitizing receptors, re-uptaking and breaking down neurotransmitters....
4
votes
2answers
1k views

Does the brain and the body use the same energy source (glucose/ATP)?

I've heard that the brain consumes quite a lot of oxygen and energy, compared to the rest of the body. What I'm interested in is if this is the kind of energy and oxygen that the rest of the body ...
4
votes
1answer
199 views

Negative feedback in the fructose metabolism in liver

What happens in liver when large amount of fructose is consumed? I vaguely remember my biochemistry lecturer telling us that the enzymes that process fructose in the liver does not have negative ...
4
votes
1answer
345 views

What do trans-fats do when in human body?

Trans fats cause health problems, especially to the heart. https://en.wikipedia.org/wiki/Trans_fat#Health_risks My guess is that all effects happen because trans-fats are inherently toxic as the ...
4
votes
1answer
44 views

How to measure heat loss in Tardigrades

I want to measure metabolism in tardigrades (a jar of 30 tardigrades). I know that an easy way to measure metabolism is heat loss; I can just measure the temperature of the water before and after a ...
4
votes
1answer
82 views

Oxidation means inflamation?

All right, I was reading article on nutrition, that focussed on content analysis of pastry-like food product for kids. I have to say that I am not sure this article would pass the imaginary smell test,...
4
votes
1answer
658 views

How was the diversity between ethanol fermentation and lactic acid fermentation evolved?

Quite simply, some organisms metabolize glucose under anaerobic conditions via Glucose->(2) Pyruvic Acid->(2)Ethyl Alcohol. Some organisms, however, metabolize to lactic acid. When did such a process ...
4
votes
1answer
56 views

How can I obtain a computer readable model of Dr. Gerhard Michal's biological pathways map?

I want to run simulations of various metabolic pathways – the project could end up becoming quite large, and having a machine readable chart would make thing a lot easier. Does anyone know if there is ...
4
votes
1answer
51 views

How can space-time affect ageing? [closed]

I recently watched the movie -"interstellar" and I came through the question that how can ageing be affected by space-time? Wherever I look, I get it as a fact that it's kind of ageing slows down in ...
4
votes
1answer
42 views

Need for two oxygen sensors in E. coli

E. coli has two oxygen sensors: FNR (fumarate-nitrate reductase) and ArcBA (Anoxic Redox Control, two component control systems). FNR directly senses the oxygen, while the interaction of ArcB with ...
4
votes
2answers
237 views

Plotting metabolic networks?

I need to draw a map of the core metabolism of E.coli. Associated with each reaction in the map I have a number that indicates the flux through this reaction. I want the map to reflect these fluxes ...
4
votes
1answer
104 views

Do mitochondria use ATP in order make another ATP from glucose?

Do mitochondria use ATP in order make another ATP from glucose, or does it use another source of energy to convert glucose to ATP?
4
votes
1answer
1k views

How are non-glucose sugars metabolized in the body?

In my biology book's section on disaccharide metabolism and glycolysis, it states that sugars other than glucose must be acted upon to enter glycolysis. Let's take sucrose as an example. Sucrose is ...
4
votes
1answer
429 views

How is ammonia removed from the colon?

“Lactulose is also used to reduce the amount of ammonia in the blood of patients with liver disease. It works by drawing ammonia from the blood into the colon where it is removed from the body.” (...
4
votes
1answer
170 views

Where does all the food go?

Food goes in, excrements come out. This seems obvious. But it seems like the mass of the excrements is less than the one of the food. Most people I asked answered: "There's a difference because it's ...
4
votes
1answer
64 views

What is the biggest facultative anaerobic metazoan known to science?

Related: What's the biggest obligate anaerobic organism discovered till now? I had always assumed that the Riftia tube worms were obligately anaerobic since they lived next to anoxic volcanic ...