The set of biochemical reactions that sustain life by directly or indirectly affecting energy expenditure and/or storage, as well as the complete regulation of those reactions and the enzymes that catalyze them; including, hormonal, cell-signaling, and substrate level regulation.

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114 views

Why use creatine phosphate?

We use creatine phosphate as an energy storage to resupply ADP with a phosphate group as our muscle cells only contain about 2-5 mM ATP. But why doesn't the muscle cells just keep 20-30 mM ATP instead ...
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53 views

Why doesn't the body optimize how many fatty acids it burns?

Ketone bodies are produced due to an excess of fatty acids being burned (accumulation of acetyl-CoA) so my question is: Why doesn't the body simply regulate how many fats it burns so it doesn't have ...
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0answers
43 views

Cholesterol's role in lipid uptake [closed]

I'm studying the digestion of fats and I understand that our dietary fats mostly consist of triglycerides. We absorb the fats and eventually they end up in a muscle/adipose cell for storage (as ...
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1answer
920 views

How can haired mammals synthesize vitamin D?

The human body can synthesize vitamin D in the skin from cholesterol, when sun exposure is adequate. But how can haired mammals do it? Do not they need it?
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1answer
544 views

How is excretion of metabolic wastes from a cell related to its size?

As with anything that is taking place within a cell, the metabolic waste too must be proportional to the size of the cell. In particular the surface area to volume ratio. But how is the waste ...
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3answers
4k views

Is there any use of CO₂ in human body?

We all know CO₂ as a waste product of metabolism . Does CO₂ have any helpful role , apart from having a role in pH of blood ?
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1answer
345 views

What do trans-fats do when in human body?

Trans fats cause health problems, especially to the heart. https://en.wikipedia.org/wiki/Trans_fat#Health_risks My guess is that all effects happen because trans-fats are inherently toxic as the ...
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1answer
57 views

Mitochondria variability per tissue in humans?

I would like to know the distribution of mitochondrial content per tissue type in humans. I understand the simple metric that energetically active or energy requiring tissues will have more ...
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3answers
209 views

What is the relationship between protein-protein interaction networks and metabolic networks? [closed]

I am trying to find out how these networks can be linked together. I know that Protein-protein interaction networks and metabolic networks both fall under the Intra-cellular type of biological ...
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2answers
99 views

How does it make thermodynamic sense for photosynthesizers to turn CO₂ into O₂?

My understanding is that animal metabolism consists of exothermic reactions like $$\ce{C6H12O6 + 6 O2 ->6 CO2 + 6 H2O + energy}$$ This makes thermodynamic sense to me. Animals need an exothermic ...
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0answers
662 views

Why do plants produce so much more sugar than they use?

I recently asked the question, "Do plants need O2 to consume energy they've stored via sugar?" to which @canadianer responded, "Yes, plants require oxygen to generate ATP from sugar. However, they ...
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40 views

Do plants need O₂ to consume energy they've stored via sugar?

This question came up as I work my way through the answers to another question I just asked. My understanding is that plant photosynthesis looks something like this (though with lots more going on ...
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1answer
65 views

Metabolism of different saccharides

Learning about carbohydrates, I wonder what the differences there are in terms of metabolism, and overall health between the different types of saccharides. In other words, does the body use ...
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1answer
44 views

How to measure heat loss in Tardigrades

I want to measure metabolism in tardigrades (a jar of 30 tardigrades). I know that an easy way to measure metabolism is heat loss; I can just measure the temperature of the water before and after a ...
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0answers
23 views

Which biosynthetic pathways take place in the plastid and were are they located?

I know that the isoprenoid, jasmonate, glucosinolate, fatty acids, chlorophyll, starch, and aromatic amino acid syntheses are located in the plastid. But I don't know if they are located in the ...
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0answers
95 views

Does the metabolic rate determine how fast the telomeres shorten?

In many papers one can read that telomeres may play an important role in longevity. According to Calado et al.1 the telomeres of mice are much longer than the telomeres of humans. However, mice have ...
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1answer
141 views

How to measure metabolic rates of microscopically small animals?

I want to measure metabolism rates in Tardigrades Metabolic rates will be assessed immediately following their exit from cryptobiosis (an animal dormant state). I know that oxygen levels is the ...
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1answer
113 views

How does the body “know” how to metabolize foreign substances

As a freshman biochemistry major, I find myself befuddled by our body's ability to perform complex chemical reactions to break down foreign substances. I can see how we would evolve explicit pathways ...
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1answer
64 views

What is the biggest facultative anaerobic metazoan known to science?

Related: What's the biggest obligate anaerobic organism discovered till now? I had always assumed that the Riftia tube worms were obligately anaerobic since they lived next to anoxic volcanic ...
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1answer
10k views

Why is the Krebs cycle considered a part of aerobic metabolism if molecular oxygen is not involved in any of the reactions in the cycle

Why is the Krebs cycle considered a part of aerobic metabolism if molecular oxygen is not involved in any of the reactions in the cycle? I originally thought that Krebs cycle was aerobic metabolism ...
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1answer
2k views

Does THC excretion increase if urine volume increases?

In regards to the body metabolizing and excreting THC: if urination is increased as a result of drinking lots of fluids, does that mean that more THC is leaving the body? To rephrase the question, is ...
4
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2answers
239 views

Plotting metabolic networks?

I need to draw a map of the core metabolism of E.coli. Associated with each reaction in the map I have a number that indicates the flux through this reaction. I want the map to reflect these fluxes ...
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2answers
268 views

How does the cell regulate different metabolic pathways?

I heard somewhere that cells use different nucleosides bound to triphosphates e.g. ATP, GTP, CTP and other modified compounds: NADH, NADPH to distinguish between different metabolic pathways and so ...
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1answer
42 views

Need for two oxygen sensors in E. coli

E. coli has two oxygen sensors: FNR (fumarate-nitrate reductase) and ArcBA (Anoxic Redox Control, two component control systems). FNR directly senses the oxygen, while the interaction of ArcB with ...
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1answer
106 views

In which way would the yeast cell cope with the excess amount of methionine in the growth media?

I guess that when there is surplus of methionine in the cell it is incorporated in the TCA cycle as a succinyl CoA, with cysteine as a by-product. But now the cell has the surplus of cysteine. What ...
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3answers
71k views

What is a coupled reaction and why do cells couple reactions?

I was wondering what exactly a coupled reaction is and why cells couple them. I read the wikipedia article as well as several others, such as life.illinois.edu but I still don't get it. Could ...
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0answers
12 views

How reactive are reduced antioxidant molecules?

When antioxidant molecules stabilize free radicals, they themselves become unstable and reactive but to a lesser degree. How reactive are these reduced antioxidant molecules? And what substance ...
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1answer
71 views

Can chitosan affect the absorption of unsaturated fatty acid?

I know chitosan will decrease the absorption of fat. However unsaturated fatty acid, such as DHA, is beneficial. Does chitosan effect the absorption of unsaturated fatty acid?
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3answers
2k views

What is the mechanism of oxygen uptake in E. coli?

How does E. coli uptake oxygen? Most of the literature I found is concerned with response to oxygen level supplied in the medium, as opposed to how much is actually transported inside. Can they shut ...
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1answer
799 views

In humans what is the last metabolic process to cease after death?

After death which of our body's metabolic processes will continue functioning for the longest?
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2answers
912 views

How do antioxidants affect human metabolism?

I'd like to know how antioxidants affect human metabolism and which ones are essential for metabolic processes.
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2answers
2k views

What is an irreversible reaction?

There are reactions with large Delta G negative values. Why these reactions are irreversible? As in: out of 10 steps of Glycolysis, 3 are irreversible steps. I need an explanation for why they are ...
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1answer
82 views

Oxidation means inflamation?

All right, I was reading article on nutrition, that focussed on content analysis of pastry-like food product for kids. I have to say that I am not sure this article would pass the imaginary smell test,...
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1answer
145 views

The smell from eating asparagus

I am wondering about one thing. I have read different accounts of this (prior to reading it on Wikipedia), so I am wondering. Here are the two versions I have read: asparagus leads in a certain ...
3
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1answer
390 views

Consumption of NAD+ in glycolysis

Out of 10 steps in glycolysis, only one reaction- Glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (PGP), uses NAD+ and thereby producing NADH. Furthermore, this very step is solely ...
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1answer
2k views

Why our body does not produce polyunsaturated fatty acids?

Our body does not produce two polyunsaturated fatty acids (PUFA): linoleic acid and alfa-linolenic acid. I am thinking reasons for it. Saturated fatty acids have more energy than unsaturated. ...
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1answer
260 views

naturally occuring fatty acids

The double bonds in naturally occurring fatty acids present in our body are in cis configuration while the enzymes for beta oxidation can act on trans double bond. Then what will be the significance ...
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1answer
104 views

What organism most efficiently converts a given quantity of mass into heat?

Question I am trying to answer: In the popular film The Matrix, heat given off by humans is harvested as an energy source. I wondered, if this were possible, would humans be a good organism to choose?...
3
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1answer
179 views

Why doesn't Diabetes cause death by starvation?

The main cause for diabetes is lack of insulin in the body. Insulin is the hormone that allows body cells to absorb glucose from the blood. With out insulin, the body cells can't get glucose from the ...
3
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1answer
53 views

bacterial cell wall degradation in humans

can human degrade the D-amino acid present in bacterial cell wall, I'm confused about it i have read somewhere that human can do so.If yes than why we need antibiotic to kill bacteria???If it is not ...
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2answers
584 views

Where can I find a list of common enzyme cofactors and/or co-enzymes?

Where can I find a list of enzyme cofactors and/or co-enzymes, ordered by how common they are? For example, $O_2$, $H_2O$, $ATP$, $ADP$, $NAD$, should be ranked in the first places, because they ...
2
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1answer
175 views

what is the margarine metabolism in our body?

margarine is commonly used food ingredients that contribute to both inflammation and obesity , but actually I want to know the margarine metabolism in the human body I can find some resources talk ...
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1answer
431 views

How should I feed and keep an ant queen?

I have captured wandering ant queen. I guess she was just fertilised and was looking for a place to start a hive. I'd like to create my own ant hive in artificial environment. I unfortunately only ...
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1answer
172 views

Currency metabolites vs. current metabolites: What's the right term?

I have seen the two terms currency metabolite and current metabolite used interchangeably. Is there a consensus on which is the ...
7
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1answer
208 views

What are the lifetimes of cellular components on organelle or molecular level?

I was thinking that even though I know how generally the cell works, I don't really have a feeling of how volatile it is. I want to know what is the lifetime/turnover rate of different constituents of ...
2
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1answer
74 views

Why is duck fat less saturated than cow fat?

Why does the composition of fat in animals vary? Is there an evolutionary advantage to producing fat that is less or more saturated?
2
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1answer
677 views

Anaerobic respiration choice in E. coli

Under anaerobic conditions E. coli has two options to generate ATP: fermentation (substrate-level phosphorylation), and respiration (proton gradient, chemisomotic phosphorylation). Which is favored? ...
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1answer
776 views

What marine animals exhibit deep hibernation/aestivation?

Do marine animals exhibit deep hibernation/aestivation as land-based creatures do? If not, Why?
5
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1answer
134 views

Selective Androgen Receptor Agonist

I'm looking for an inducer that strongly activates the androgen receptor, but not the glucocorticoid receptor that is not DEA regulated. I know that SARMS (Selective Androgen Receptor Modulators) are ...
0
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1answer
49 views

Feedback affecting myocyte metabolism in humans

I understand that there are several reserves available to muscle that can be tapped for ATP, and that each reserve is being used to some degree at all times. Are these reaction rates purely due to ...