The set of biochemical reactions that sustain life by directly or indirectly affecting energy expenditure and/or storage, as well as the complete regulation of those reactions and the enzymes that catalyze them; including, hormonal, cell-signaling, and substrate level regulation.

learn more… | top users | synonyms

2
votes
1answer
50 views

What are calories and how to burn them? [closed]

What exactly is a calorie? When burning calories, do we always lose fat? I have tried many apps to measure calories, do they give exact amounts? How many calories should be taken a day?
2
votes
1answer
120 views

Why would the citrulline content of the watermelon be so high?

Citrulline is a non-proteinogenic amino acid (that is, citrulline is an amino acid that is not coded for in mRNA), and it is an important metabolic intermediate in the Urea Cycle. The Urea Cycle is ...
2
votes
1answer
69 views

Are there differences in energy of glucose isomers?

There are many isomers of glucose, including galactose and fructose. Do they have different chemical energy levels, and why? What makes galactose and fructose useful compared to glucose, and would ...
2
votes
3answers
1k views

What are the differences between how glucagon and cortisol work to increase blood sugar?

As I understand, both cortisol and glucagon cause an increase in blood sugar concentrations. However I don't understand how they work differently or why they work separately. I would be very grateful ...
2
votes
1answer
260 views

naturally occuring fatty acids

The double bonds in naturally occurring fatty acids present in our body are in cis configuration while the enzymes for beta oxidation can act on trans double bond. Then what will be the significance ...
2
votes
1answer
336 views

How do Gram + bacteria use a proton gradient for F-type ATPase?

Does anyone know of any papers showing how Gram positive Fermiculates or Actinobacteria use a H+ gradient for an F-type ATPase, It seems impossible since there is no outer LPS membrane to maintain ...
2
votes
1answer
72 views

How much solar energy required to compensate food?

Just curious, how much solar energy can power an (herbivore) animal? Specifically, is it enough sunlight on Mercury (4 to 10 times brighter than on Earth) to "feed" a zebra? Will it be sufficient at ...
2
votes
1answer
34 views

Can lactate be created in ketosis?

After looking at Cori Cycle (from wikipedia) I have a question about how the lactate can be produced in ketosis. According to this article: in a low-glucose state, where the body senses that ...
2
votes
1answer
45 views

Does the body prioritise the use of available sugar before fat?

Let's say you eat a very unhealthy snack that contains 90% sugar and 10% fat. Would somatic cells not start using the fat for energy until all the sugar is used up? Does the body not use fat at all ...
2
votes
1answer
25 views

Where does the lactate produced by tumors go?

Tumors are known to burn glucose and secrete lactate (this is known as the Warburg effect). Where does this lactate go? Does it steadily accumulate in the neighborhood of the tumor? This doesn't ...
2
votes
1answer
113 views

How does the pancreatic beta-cell know how much insulin to secrete in response to glucose?

How do $\ce\beta$-cells know how much glucose is in the blood? I know that when glucose enters a beta cell it triggers the cell to produce insulin. $\ce\beta$-cells trap glucose by converting it into ...
2
votes
1answer
101 views

Does creatine-phosphate (CP) supplementation regenerate NADH?

I have the following facts: It is possible to convert ATP <-> creatine vice-versa. (ref - non scientific) CP supplementation protects against metabolic syndrome. ref1 ref2 Fructose digestion ...
2
votes
2answers
88 views

Conversion and storage of glucose to glycogen

Why is excess glucose, synthesized to glycogen, stored only in limited amounts, as compared with lipids/triglycerides that are stored in our body? Why is mature glycogen arranged (polymerized) in 12 ...
2
votes
1answer
210 views

How does the human body use energy?

As far as I know the glucose gets processed from carbs and fats and as a result carbon dioxide, water and "energy" are released. The carbon dioxide and water are expelled by the body, and then energy ...
2
votes
1answer
172 views

Currency metabolites vs. current metabolites: What's the right term?

I have seen the two terms currency metabolite and current metabolite used interchangeably. Is there a consensus on which is the ...
2
votes
1answer
175 views

what is the margarine metabolism in our body?

margarine is commonly used food ingredients that contribute to both inflammation and obesity , but actually I want to know the margarine metabolism in the human body I can find some resources talk ...
2
votes
2answers
540 views

Why isn't phosphorus or nitrogen a limiting nutrient for animals?

Nitrogen and Phosphorus are usually the limiting nutrient for plants, especially for algae. Phosphorus is used for DNA, ATP and phospholipids, and Nitrogen is used for pretty much every protein a ...
2
votes
1answer
114 views

How usable is the Human Metabolic Model to predict biomass?

In order to use the Human Metabolic Model for Flux Balance Analysis of specific cancer cell lines, we would like to know what sort of flux values have been determined for the Human Metabolic Model. ...
2
votes
1answer
542 views

How is transport of glucose into prokaryotic cells different from transport into eukaryotic cells?

I was reading page 92 of Fundamentals of Microbiology, 4th edition, which states In facilitated diffusion, the substance (glucose, for example) to be transported combines with a plasma membrane ...
2
votes
1answer
78 views

Are (baseline) high blood levels of melatonin associated with either circadian rhythm or mood disorders?

(Exogenous) melatonin is administered at night for treatment of circadian rhythm disorders, but melatonin taken during the day is linked with depression. I would like to know if high blood levels of (...
2
votes
1answer
774 views

What marine animals exhibit deep hibernation/aestivation?

Do marine animals exhibit deep hibernation/aestivation as land-based creatures do? If not, Why?
2
votes
1answer
81 views

What is the role of Homocysteine in cognitive function?

I'm looking at this link : Homocysteine and cognitive impairments and am looking for more information on specific cognitive impairments associated with elevated levels Homocysteine. That article is ...
2
votes
1answer
50 views

Why does protein kinase C activated by different means have different effects?

I could be way off base but I think I remember learning that Protein Kinase C has some effects when activated by one pathway and other effects when activated by another. How does this happen? Is it ...
2
votes
1answer
42 views

How many calories do gut bacteria burn?

It has become well-accepted that microbiota of the gut (a.k.a. gut bacteria) consume calories that are ingested and can have significant effects on energy metabolism in humans. For example, if you ...
2
votes
1answer
68 views

Metabolic efficiency for fats and sugars

I am making an exercise for physics students about the first law of thermodynamics, burning heat and evaporation heat. So my idea is to use cycler which runs on fats and sugars where proportion ...
2
votes
2answers
43 views

Is there a known or quantifiable correlation between capsaicin and its effect on the body's metabolism?

I've often heard that spicy foods can speed up your metabolism, I presume, due to the capsaicin. Though I'm sure this is a minor effect - I doubt eating a pound of jalapenos a day will help me lose ...
2
votes
1answer
99 views

What happens when we eat excess fat?

The fats in our body are stored in fat cells. When we over eat fats does the size of our fat cells increase, are more fat cells generated, or do we "throw out" excess fat?
2
votes
1answer
73 views

What is the meaning and significance of extreme pathways

Can someone please explain me what extreme pathways are? I found this definition in this article: Extreme pathways are a unique and minimal set of vectors that completely characterize the ...
2
votes
1answer
41 views

MTHFR recessive alleles and B-vitamins

I know that being heterozygous or homozygous recessive for the MTHFR gene prevents that person from being able to process and use folate and B-12. It causes an unhealthy level of homocysteine to ...
2
votes
1answer
65 views

Metabolism of different saccharides

Learning about carbohydrates, I wonder what the differences there are in terms of metabolism, and overall health between the different types of saccharides. In other words, does the body use ...
2
votes
1answer
89 views

Aerobe or facultative anaerobe organism that metabolizes acetate?

I'm assuming bacteria, but will take any suggestions. Organism must survive primarily on the acetate (plus trace elements), but I can give/take electrons, if necessary. Not interested in strict ...
2
votes
1answer
74 views

Why is duck fat less saturated than cow fat?

Why does the composition of fat in animals vary? Is there an evolutionary advantage to producing fat that is less or more saturated?
2
votes
1answer
194 views

How can we distinguish blended flavors?

As far as I know, humans can distinguish between 5 basic tastes based on various molecules in food and their interactions. There's a level to all 5 so there can be an endless variety of tastes, and we ...
2
votes
1answer
9k views

What are the differences between white and brown adipose tissue?

What are the differences between white and brown adipose tissue? Here are some that I have come across: ...
2
votes
0answers
22 views

Can the respiratory quotient be calculated from a formula or must it be measured directly?

I found the following question on the Respiratory quotient: A normal human diet has a Respiratory quotient (RQ) of approximately 0.85. Given that pure oxidation of fatty acids has a Respiratory ...
2
votes
2answers
38 views

Where do plants obtain the metal ions needed for biological processes?

Enzymes employ metal ions (e.g. Mg, Cr, Mn, Fe, Co, Ni, Cu, Zn) for catalysing certain reactions. Let's consider planting a seed. Where will it obtain these metal ions from? Just from water?
2
votes
0answers
30 views

What is the function of CETP?

I read up that CETP transfers cholesterol from HDL, which collected it from tissues, to VLDL. This VLDL is then sent back to the tissues, ultimately forming LDL internalised by cells. What is the ...
2
votes
0answers
28 views

What is the rationale behind reverse cholesterol transport?

Reverse cholesterol transport is transport of cholesterol from the tissues back to liver/VLDL. My question is why do the tissues have this extra cholesterol in the first place? Why would you ...
2
votes
0answers
32 views

Why lactate inhibits growth (or enhances death rate)?

Extracellular lactate tends to inhibit cellular growth or enhance cell death. This happens in the vicinity of tumors and in cell cultures. See for example this reference: Ozturk, Sadettin S., Mark R....
2
votes
0answers
29 views

Metabolic control theory: proof of the summation theorem?

I'm looking for a rigorous proof of the summation theorem of metabolic control theory. The only sources I find are the original papers by Kacser and Burns 1973 and Heinrich and Rapoport 1974, both of ...
2
votes
0answers
23 views

Which biosynthetic pathways take place in the plastid and were are they located?

I know that the isoprenoid, jasmonate, glucosinolate, fatty acids, chlorophyll, starch, and aromatic amino acid syntheses are located in the plastid. But I don't know if they are located in the ...
2
votes
0answers
95 views

Does the metabolic rate determine how fast the telomeres shorten?

In many papers one can read that telomeres may play an important role in longevity. According to Calado et al.1 the telomeres of mice are much longer than the telomeres of humans. However, mice have ...
2
votes
0answers
51 views

Is body energy production and consumption cyclical?

If we look into how energy is produced by the humans, it always involves some kind of periodicity: fuel combustion rotates engines, water rotates turbines, nuclear chain reactions heat up water, which ...
2
votes
0answers
89 views

Why is a nicotinamide-tryptophan combination used to treat affective episodes in a few older clinical trials?

At least one of the journal articles that reported on such clinical trials allured to the nicotinamide-tryptophan pathway that I assume must be related to the metabolism of tryptophan into serotonin ...
2
votes
0answers
144 views

Are simple esters like those used as flavouring agents metabolised into their constituent carboxylic acids and alcohols in the human body?

By this I mean to ask whether say ethyl butanoate is hydrolysed in humans into ethanol and butyric (butanoic) acid. This is of interest to me as a pharmacology researcher because butyric acid, for ...
2
votes
0answers
43 views

How much does a human brain's metabolic rate vary? [duplicate]

Possible Duplicate: How does brain energy consumption depend on mental activity? Our brains consume about 20% of our energy when we're at rest. How variable is a human brain's energy ...
2
votes
1answer
330 views

Why do mice have a higher metabolism?

Mice and other small animals have higher metabolic rate than humans. How does that happen on cellular level, if we look on one cell in the mouse body? What is it in this cell that will be different?...
1
vote
3answers
69 views

What is the actual storage form of energy in muscles? ATP or Glycogen?

I was asked this question in my latest exam. I think the answer is Glycogen because ATP doesn't store energy for a long time so it isn't the ACTUAL storage of energy. Some classmates argue that in ...
1
vote
2answers
1k views

carbohydrates and lipids as a source of energy? why?

Why carbohydrates and lipids basically used as a sources of energy? Why only proteins are used as building blocks of all the creations? Yes there are some parts of cells like cell walls in which ...
1
vote
1answer
118 views

Is it easier to burn a calorie of fat or a calorie of a carbohydrate?

Say someone eats 100 calories of chocolate vs. 100 calories of carrots. Something tells me that eating the chocolate will lead to you generating more fat. Will it? Is it harder to burn the calories ...