The set of chemical reactions that happen in the cells of living organisms to sustain life.

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What is the molecular basis of hangovers?

Well, most of us have experienced the wonderful feeling of the dreaded hangover. How does it work exactly? I imagine it has something to do with dehydration but what are the underlying mechanisms? ...
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Why is glucose our primary source of energy?

Is there any evolutionary reason for glucose being the "main" molecule used as a source of energy, beginning with glycolysis and subsequently cellular respiration (after being converted to two ...
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How much does a human brain's metabolic rate vary? [duplicate]

Possible Duplicate: How does brain energy consumption depend on mental activity? Our brains consume about 20% of our energy when we're at rest. How variable is a human brain's energy ...
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213 views

How long does it take for E. coli to shift feedstocks?

With our fermentations we're noticing that it takes an appreciable amount of time for E. coli (K12 variant) to change from being metabolically streamlined on amino acids to being metabolically ...
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obesity risk and single gene polymorphisms

I read a fairly recent meta-analysis of studies into the association between adult obesity and polymorphisms of the FTO gene (Peng et al., 2011). The paper looked at 59 studies and found that "FTO may ...
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218 views

Is there such thing as a generic “metabolic type”?

A while ago I picked up a book called "Eat right for your metabolic type". The book discussed the effects of the endocrine system on the overall shape and the speed of metabolism. The book outlined ...
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Does mixing alcoholic drinks really make you more drunk?

There is plenty of anecdotal evidence ("beer after wine and you'll feel fine, wine after beer will make you feel queer") that mixing alcoholic drink types leads to a stronger effect, but I can't find ...
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27 views

How usable is the Human Metabolic Model to predict biomass?

In order to use the Human Metabolic Model for Flux Balance Analysis of specific cancer cell lines, we would like to know what sort of flux values have been determined for the Human Metabolic Model. ...
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295 views

Circulation through the liver in light of drug metabolism

I have a lingering question which stems from an answer that I gave to What hydrolyses aspirin within the digestive tract and blood stream? When a drug or any other substance is absorbed into the ...
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What are good data on the Human Metabolic Model and where can I get them?

Trying to get a good SBML representation of the Human Metabolic Model for use in Flux Balance Analysis and drug targetting (i.e. gene knockout) simulations. What are good sources for these data? ...
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How to relate human metabolic model reactions and cancer drug targets / reactome items?

Trying to find a way to take a cancer drug (from CancerDR, for instance) and infer the metabolic reactions that are affected by it in the Human Metabolic Model. Essentially, I would like to know ...