Do red blood cells have no MHC? (I have often heard that they do not.) If so why are they not destroyed by immune cells?
I read that Doherty and Zinkernagel found that MHC- heterozygotes present more antigens to the immune system than homozygotes; yet, the infected heterozygous mice in their experiment all ...
What evolutionary process lead to so much variation in MHC? What is the advantage of having such variation?
I have read that neurons have proportionately less MHC molecules than other cells of the body. What is the advantage of this?
T-cells recognize the MHC molecules and body's own peptides. When it doesn't, it alarms the immune system. But do T-cells express MHC molecules ? If so, how are they using it? If not, what happens ...