Micro RNA (miRNA) are a class of small (22 nucleotide in the mature form) non-coding RNA. They are present in plants and animals and function as transcriptional and post-transcriptional regulators of genes. They bind to a complementary region in the transcribed gene to form doublestanded RNA ...
Generally in miRNA prediction most researchers do as Blast search with a set of miRNAs downloaded from miRBase with the parameters they require. Later on usually custom methods are utilized to get an ...
I aligned all miRNAs available to the supercontigs of a particular genome with certain parameters (e value of 0.01 and a word match of atleast 7 as suggested in this paper). I have also isolated the ...
I am trying to predict the secondary structure of certain predicted pre-miRNAs through mFOLD which is the generally accepted technique for structure prediction in most studies. I am finding it hard to ...
Have there been any experimentally-verified systems of microRNAs targeting a gene set (e.g., in cancer, perhaps)?
In plasma and other body fluids, miRNAs can be found. They not only originate from dying cells but also from active secretion and are usually 'packed' into vesicles/lipo-proteic structures (i.e. ...