The organelle in which the main stages of respiration occurs in eukaryotes
17
votes
3answers
420 views
How many times did endosymbiosis occur?
According to the endosymbiont theory, mitochondria and chloroplasts originated as bacteria which were engulfed by larger cells. How many times is it estimated that this occurred in the past? Are there ...
7
votes
1answer
39 views
Cell Respiration and Oxidative Phosphorylation
Why and how does the proton travelling through the stalked particle in the inner mitochondrial membrane, cause a conformational change in the ATPase?
7
votes
1answer
90 views
What preceded ATP synthase?
ATP Synthase is ubiquitous throughout life on earth and so most probably evolved within the last universal common ancestor (LUCA) before that lineage diversified into the various kingdoms of life.
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2
votes
1answer
38 views
PGC-1β Sod2 limiters/blockers
I'd like to block a percentage of PGC-1β or Sod2 expression. According to the following paper's figure beta-blockers inhibit some expression of PGC-1α. Are there any medicines/chemicals which safely ...
3
votes
1answer
42 views
mutant down but not out
I am interested in a gene which is null lethal but I need to temporary induce diminished capacity. If a cell is homozygous is it possible to induce heterozygous phenotypes or a partial knockout from ...
3
votes
1answer
212 views
Slow-oxidative fibres vs fast-glycotic fibres
Why do slow oxidative muscle fibres contain more mitochondria compared to fast-glycolytic muscle fibres?
6
votes
1answer
230 views
Does every mitochondrion in a cell contain the same DNA?
I know that mitochondria of eukaryotes have their own DNA, more similar to that of bacteria than to the rest of the cell's DNA. I also know that a cell can have plenty of mitochondria, and I ...
7
votes
1answer
137 views
Why aren't mitochondria and plastids considered symbiotes of eukaryotic cells?
Mitochondria and plastids have their own DNA, their own membranes, and their reproduction is not tied to the reproductive cycle of the host cell. However, they are considered to be organelles rather ...
14
votes
1answer
175 views
How fast does the rotor in ATP synthase spin?
I'm sure the exact frequency varies, but does anyone know roughly how many revolutions per minute / second the rotating center part makes?
6
votes
0answers
51 views
Pancretic Acinar Cell - ATP, calcium concentration data
I need to find a decent source of data for concentration of ATP and calcium in the pancreatic acinar cell.
So far all I can find is ATP or calcium 'levels' based on fluorescence , which are not ...
8
votes
1answer
167 views
How is the number of mitochondria in a cell regulated?
How does the cell regulate the number of mitochondria in a cell? What happens when there are too many or too few?
9
votes
2answers
269 views
Do mitochondria simply automatically convert glucose to ATP?
I wonder whether there is any intelligent decision-making in mitochondria in the timing of their operation.
Do they simply begin ATP production as soon as the correct reactants are present?
Or, ...
5
votes
1answer
137 views
What is the benefit for cells having the ATP production regulated in mitochondria compared to being from the nucleus?
Mitochondria have their own DNA and appear to be loosely connected to the nucleus and it role.
Why are the functions of mitochondria not in the nucleus? Why doesn't the nucleus control the ...
2
votes
1answer
60 views
Substrates of cytochemical reactions in this immunostaining
Expression of extracellular protein Laminin 9 alpha-4 chain in human skeletal muscle.
Indirect immunostaining with HRP immunostain marker. Ob.x40.
I have unsuccessfully searched NCBI -database, JSTOR ...
