Messenger RNA is produced during transcription before it leaves the nucleus to be be translated by a ribosome. This produces a sequence of nucleic acids for which mRNA is considered the template.

learn more… | top users | synonyms

3
votes
0answers
27 views

What is the meaning of conservation site in miRNA-mRNA pairing context?

I am not biologist and just work in Bioinformatics field. Does anyone know what is the meaning of conservation in the context of miRNAs and their pairings to mRNAs? Example: Each of these duplexes ...
2
votes
0answers
20 views

Gene expression for mouse feeder cells (inactivated MEFs)

I'm looking for a paper with gene expression data for mouse feeder cells, inactivated by gamma radiation or mitomycin C. Ideally I'd like RNA-seq data but I'll use microarray data if that's all there ...
1
vote
0answers
32 views

Which data format for mRNA expression matrix is necessary to run pathway analysis with Paradigm?

I am running Paradigm on a matrix of mRNA expression. I read Vaske, Charles J., et al. "Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using ...
1
vote
0answers
12 views

How to automate this custom gene expression microarray chip?

I have 16 gene sequences that I am interested in their detection in clinical samples. I already measured their RNA levels by using RT-qPCR technique and their benefit has already been proven to help ...
0
votes
0answers
9 views

What is the control level of activation in Paradigm?

I am trying to use Paradigm for pathway analysis on mRNA expression data. In Sample-Specific Cancer Pathway Analysis Using PARADIGM it is written that Each entity can take on one of three ...