A change in an organism's genomic sequence.

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Is it possible to elicit transient gene silencing by using virus induced gene silencing (VIGS) in plants?

I am looking for a molecular tech' which could result in transient gene silencing in plants. The objective is to not make transgenic plant, but to use these tech' to silence a gene of interest for a ...
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Are mature trees as susceptible to mutation from exposure to radiation as seedlings?

If a plant, say a ficus or a teak, as a sapling were exposed to radiation, and a tree of the same species were present at the same distance, which of the two would be more likely to mutate?
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Penetrance Calculation of a Spontaneous Mutation

I'm trying to estimate the penetrance of a disease in a population given a rare spontaneous mutation that confers predisposition in an autosomal dominant manner. Given that the mutation is ...
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What is TILLING?

How does TILLING (Targeting Induced Local Lesions in Genomes) work? What is needed to perform a TILLING experiment, and what kind of information can we get out of it?