The theory by which mutations in the genetic code lead to differences from the previous phenotype that, should they be advantageous to an organism's survival to reproductive age, may be passed on to offspring.

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Effect of natural selection on the phenotypic variance. Empirical studies

Short background Theoretically speaking, natural selection causes a decrease in genetic variance and because the environmental variance should remain unchanged, natural selection causes a decrease of ...
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Can I force evolution in a group of cells by removing all the smaller cells?

I actually have algae growing in water in a container. I was thinking if it was possible to filter the water so that all the small cells will be filtered out and only the bigger ones will remain to ...
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Heterozygosity under genetic drift

The wright-Fisher model of genetic drift is: $$p_{ij} = \binom{2N}{j}\left(\frac{i}{2N}\right)^j \left(1- \frac{i}{2N}\right)^{2N-j} $$ ,where $\binom{2N}{j}$ is a binomial coefficient. From this ...
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How does GC-content evolve?

Background GC-content refers to the frequency of base pairs that are either C or G in the genome, or in other words the number of GC base pairs divided by the addition of the number of GC base pairs ...
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List of the biggest companies that work in selective breeding

Looking at this question, I've been wondering, What are the biggest private companies which work in both animal and non-animal selective breeding? Let me know if Biology.SE is not appropriate for ...
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Effect on fitness of mutations

What is the distribution/probability density function (PDF) of impacts on fitness of new mutations? I very welcome any partial answer that does not give the whole PDF but just some information ...
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Dominance/recessivity of new mutations

What is the distribution/probability density function (PDF) of recessivity/dominance of new mutations? I very welcome any partial answer that does not give the whole PDF but just some information ...
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Additive genetic variance with $n$ loci

The genetic variance of a quantitative trait (the quantitative trait in question is fitness) can be express as the sum of two components, the dominance and additive variance: $$\sigma_D^2 + ...
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Additive genetic variance with $n$ alleles

The genetic variance of a quantitative trait (the quantitative trait in question is fitness) can be express as the sum of two components, the dominance and additive variance: $$\sigma_D^2 + ...
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DNA adaptation in human life

Does our DNA adapt by human lifetime? Or do we have the same genetic information from birth to death? I mean: What is usually called "evolution" means "natural selection" like this: ...
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Could mating/recombination be responsible for evolution of entirely novel features?

The diploid chromosomal architecture is rather interesting. For example, because of diploidy we Humans have to mate. Of course in that sense, because diploid organisms often have mate, this has led to ...
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How do I calculate the change in allele frequency in a haploid population under selection?

From this book For simplicity, let us consider a haploid organism and assume that the frequencies of alleles $A_1$ and $A_2$ are given by $x$ and $y=1-x$, respectively. We also assume that the ...
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Effective population size and overlapping generations

From this book; If generations overlap, then the effective population size $N_e$ does not equal the population size $N$. I know mathematical formulations in order to find the effective population ...
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Linkage disequilibrium with $n_l$ loci $n_a$ alleles

Linkage disequilibrium $\left(D\right)$ for two bi-allelic loci is defined as: $$D=X_{11}X_{22} - X_{12}X_{21}$$ , where $X_{11}$, $X_{12}$, $X_{21}$, X$_{22}$ are the frequencies of the haplotypes ...
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Selection on linked loci in a diploid population

Let’s consider two linked loci $A$ and $B$ that are both bi-allelic. In consequence, we have four different possible haplotypes $A_1B_1$, $A_1B_2$, $A_2B_1$, $A_2B_2$, which frequencies are $X_1$, ...
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Is Natural Selection like a Copy Editor?

I am stuck on a Homework Question. It says: Evaluate the following statement: “Natural selection works like a copy editor; it works only with what is already present in a population.” (Note: ...
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Why does the slope of parent-offspring regression equals the heritability in the narrow sense?

Background ---- Notations and assumptions ---- let $W_{ij}$ be the fitness associated to the genotype $AiAj$. $x$ is the frequency of the allele $A1$ in the population. The frequency of the allele ...
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Does recombination increase the additive genetic variance for fitness?

On this article, first column, eighth line of the introduction: By bringing together favourable alleles from different chromosomes, sex and recombination increase the additive genetic variance for ...
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What indices can we use to describe fitness landscapes?

We usually talk of smooth or rugged fitness landscape. Are there any (standard) indices to measure the "structure" of fitness landscapes? For example, one might consider the mean epistatic ...
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question about directional selection

Cattle breeders have improved the quality of meat over the years by which process? A) artificial selection B) directional selection C) stabilizing selection D) A and B E) A and C I know the answer is ...
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Fisher's Fundamental Theorem of Natural Selection

Ronald Fisher discovered what he, with humility, called the Fundamental Theorem of Natural Selection. This theorem says (in its modern terminology): The rate of increase in the mean fitness of any ...
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Linkage disequilibrium, genetic drift and fitness variance

The very first two sentences of the abstract of this article is: "In finite populations subject to selection, genetic drift generates negative linkage disequilibrium, on average, even if selection ...
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260 views

Ka/Ks (dN/dS) analysis module for Python?

From this wiki article: In genetics, the Ka/Ks ratio (or ω, dN/dS), is the ratio of the number of Nonsynonymous substitutions per non-synonymous site (Ka) to the number of synonymous ...
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Why do animals only eat some parts of their food?

For example monkeys/apes only eat part of a fruit and then throw the rest. Cats (big and small species) only eat some parts of their prey and then they abandon it. Humans on the contrary leave as few ...
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Empirical evidence for Group Selection?

A controversial concept in Biology "Group Selection", has caused confusion and conflict amongst scientists since the since the mid 1990s. The more general realm of study is termed the "unit of ...
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Natural enemies boost deep evolutionary fitness?

"Two species that reduce one another's fitness on microevolutionary (short-term) timescales can increase each other's macroevolutionary (long-term) fitness" Opinions? Intuitive Examples: ...
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Assumptions of Hamilton's rule

Which elements of the following list are assumptions of the Hamilton's rule? Population structure (non-panmictic population) Additivity = Fitness of the heterozygote equals the mean of the ...
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Reformulation of Hamiton's rule

Who (and in which article) was the first to reformulate Hamilton's rule using the letters $B$ and $C$?. See below comments on this reformulation. Hamilton, in his 1964's article gave a mathematical ...
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Correlation between genome size and mutation rate?

Martin Nowak in his book "Evolutionary Dynamics" talks about a given correlation between genome size and mutation rate. What correlation does exactly exist between these two concepts? Is it a ...
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What does fitness really mean?

Fitness is certainly the most important concept in the theory of evolution. My question does not have to do with practical measures of fitness but with the theoretical definition of it. I am a bit ...
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What is the relationship between sexual and and natural selection?

In http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12701.html, they say: Thus, it seems that the diverse coloration in this species is promoted by both natural and sexual selection. ...
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Probability of Extinction under Genetic Drift

Here is the Wright-Fisher model of genetic drift: $$\frac{(2N)!}{k!(2N-k)!}p^kq^{2N-k} \Leftrightarrow \binom{2N}{k}p^kq^{2N-k}$$ where $\binom{2N}{k}$ is the binomial coefficient. This formula ...
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1answer
53 views

Who was the first to talk about evolvability?

"Evolvability is the capacity of a system for adaptive evolution." (source) There are several other definitions though: Who was the first person to use the word "evolvability"? Who was the first to ...
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The concepts of relatedness - Hamilton's rule and kin selection

Here is a quotation from this wikipedia page The relatedness parameter (r) in Hamilton's rule was introduced in 1922 by Sewall Wright as a coefficient of relationship that gives the ...
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Empirical evidence for species selection

Do we have any empirical evidence in favor of species (or lineage) selection? Do we know some cases that can only be explained (or seem to be only explained) by lineage selection? What are today the ...
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Is love biologically useful?

I thought about this statement a while ago: Natural selection sucks, it says those who love too much (or too many) will die the easiest and fastest. Sad but true. Only family (biologically of ...
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Phenoptosis, behavior evolved for good of species?

I was reading this and felt like the argument is being made that organisms die for the good of species. Isn't this nonsense? This especially bugged me: "'Age-induced, soft, or slow phenoptosis'" ...
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Does evolution take place universally?

Why does evolution (namely the evolution of primates into humans) take place both uniformly and universally on the earth? Why aren't there any creatures who have not taken the same evolutionary steps ...
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What evolutionary adaptations cause trees to grow tall?

I think there are some obvious costs for trees to grow tall. Carbon and other nutrients costs, maintenance cost, energy cost (for growing, to bring water (and nutrients) up to the higher leaves, ...
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Is there variation of AT/CG ratio along species?

Chargaff's rules say that the number of Adenine of the number of Thymine in a genome are equal (nA=nT) and similarly nC=nG. This makes obvious sense knowing that C binds to G and A to T. But what ...
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Model for fluctuating selection

Is there any mathematical model to predict the behaviour and long-term consequence of counter-acting selection at different time scale? For example, let's consider the bi-allelic gene $A$, with ...
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Are there any scientifically based predictions or theories of future human evolution?

Reading this question of the stack exchange got me thinking. I believe human evolution is an ongoing process and will not stop. Are there any predictions/theories about the phenotypes and genotypes of ...
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Eusociality and Natural selection?

Eusociality, particularly focusing on the presence of certain altruistic sterile organisms within the social set-up creates questions as to why would the process of natural selection have favoured the ...
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Low complexity region and relaxed selection

I'm reading a text (Wagner, 2007) on identifying positive selection. In paper, the author says that low complexity regions are known to be associated with relaxed selection. I'm trying to understand ...
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Structure of fitness landscapes in the NK model

The NK model of rugged fitness landscapes consists of $N$ sites where fitness contribution of each site depends on its state $\{0,1\}$ and is epistatically affected by $K$ other sites. When defining ...
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How does natural selection favour large body mass and size (or so it seems)

I was walking through a park this afternoon and observed a few birds having fun flying around and it got me thinking why would natural selection favour birds with flesh at all if it hinders their ...
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Why is Galapagos island so special?

I am not a biologist so the question may be very stupid. I have no idea. Why did Darwin formulate his theory of evolution just after his visit to the Galapagos island? Why is it so special from the ...
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Have proteins been observed to come into existence through mutations and natural selection?

What is an example of a functional protein that has been observed (in real time) to have come into existence through mutations and natural selection (not through an existing one being made defective). ...
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Genetic Diversity and Adaptation

I am somewhat new to evolutionary biology, having studied it on my free time as a computer science student. There is one particular thing that has always bothered me for which I have not seen a good ...
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effect of background selection on promoter regions compared to distant enhancers?

Has anyone looked at the effect of background selection on the levels of conservation of promoter regions compared to distant enhancers? Do promoter regions have a higher conservation due to ...