The theory by which mutations in the genetic code lead to differences from the previous phenotype that, should they be advantageous to an organism's survival to reproductive age, may be passed on to offspring.

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Distribution of fitness in wild populations

If I get out in the wild observe wild populations and measure the distribution of fitness $f(w)$ in a given population. What will I find out? Will I observe a Gaussian distribution, a Poisson ...
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53 views

What is a sex-biased gene?

How do you define a male-biased gene and a female-biased gene as they are found in the abstract of this article.
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103 views

Definition of Sexual Selection?

How do you define Sexual Selection (SS)? (One might want to subdivide SS into intra- and inter- SS to answer) Is SS clearly different from Natural Selection (NS)? Is SS nested within NS or are NS ...
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111 views

problem with natural selection [duplicate]

I fail to see how natural selection can build any kind of new functionality. New functionality in a design requires sacrificing a complex series of meanwhile useless steps before the new ...
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135 views

Two-fold cost of sex and r/K selection theory

This article cites a bunch of articles (I haven't been through them) that the effect of the two-fold cost of sex is "reduced" in stable environment or in K-selected environment. It says: [..] the ...
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190 views

Evolution and the levels of selection

Reading Okasha's "Evolution and the levels of selection" he talks about "the levels of selection problem." There is a bit of a problem with this opening chapter because, while he talks about why the ...
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Has it been enough time for evolution through simple natural selection?

Let first state that I understand natural selection. I am not asking if evolution happened. I see evolution as a fact, but I do not assume the current theory of natural selection as fact. I wonder if ...
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155 views

Effects of Genetic Drift on Linkage Disequilibrium

From what I understood of @Canadianer's answer here... Genetic drift randomly causes negative or positive linkage disequilibria, by changing allele frequencies through random sampling. Natural ...
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46 views

Definition of Linkage Desiquilibrium (LD)

According to wiki, linkage disequilibrium $D$ equals $$D = x_{11} - p_1\cdot q_1$$ where: $$ \begin{matrix} \text{Haplotype} & \text{Frequency}\\ A_1B_1 & x_{11}\\ ...
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Source of information on the evolution of aging/senescence

Do you know a good review (published peer-reviewed or an online course or whatever) that offers a good overview of all hypothesis explaining the various patterns linked with aging? I'd like this ...
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118 views

Can I force evolution in a group of cells by removing all the smaller cells?

I actually have algae growing in water in a container. I was thinking if it was possible to filter the water so that all the small cells will be filtered out and only the bigger ones will remain to ...
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95 views

Heterozygosity under genetic drift

The wright-Fisher model of genetic drift is: $$p_{ij} = \binom{2N}{j}\left(\frac{i}{2N}\right)^j \left(1- \frac{i}{2N}\right)^{2N-j} $$ ,where $\binom{2N}{j}$ is a binomial coefficient. From this ...
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345 views

How does GC-content evolve?

Background GC-content refers to the frequency of base pairs that are either C or G in the genome, or in other words the number of GC base pairs divided by the addition of the number of GC base pairs ...
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132 views

List of the biggest companies that work in selective breeding

Looking at this question, I've been wondering, What are the biggest private companies which work in both animal and non-animal selective breeding? Let me know if Biology.SE is not appropriate for ...
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99 views

Effect on fitness of mutations

What is the distribution/probability density function (PDF) of impacts on fitness of new mutations? I very welcome any partial answer that does not give the whole PDF but just some information ...
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39 views

Dominance/recessivity of new mutations

What is the distribution/probability density function (PDF) of recessivity/dominance of new mutations? I very welcome any partial answer that does not give the whole PDF but just some information ...
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70 views

Additive genetic variance with $n$ loci

The genetic variance of a quantitative trait (the quantitative trait in question is fitness) can be express as the sum of two components, the dominance and additive variance: $$\sigma_D^2 + ...
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108 views

Additive genetic variance with $n$ alleles

The genetic variance of a quantitative trait (the quantitative trait in question is fitness) can be express as the sum of two components, the dominance and additive variance: $$\sigma_D^2 + ...
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97 views

DNA adaptation in human life

Does our DNA adapt by human lifetime? Or do we have the same genetic information from birth to death? I mean: What is usually called "evolution" means "natural selection" like this: ...
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Could mating/recombination be responsible for evolution of entirely novel features?

The diploid chromosomal architecture is rather interesting. For example, because of diploidy we Humans have to mate. Of course in that sense, because diploid organisms often have mate, this has led to ...
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How do I calculate the change in allele frequency in a haploid population under selection?

From this book For simplicity, let us consider a haploid organism and assume that the frequencies of alleles $A_1$ and $A_2$ are given by $x$ and $y=1-x$, respectively. We also assume that the ...
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140 views

How to calculate the effective population size ($N_e$) with overlapping generations?

From this Source: If generations are overlapping, then the effective population size $N_e$ does not equal the population size $N$. I know mathematical formulations in order to find the effective ...
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112 views

Linkage disequilibrium with multiple alleles and loci

Linkage disequilibrium $\left(D\right)$ for two bi-allelic loci is defined as: $$D=X_{11}X_{22} - X_{12}X_{21}$$ where $X_{11},\ X_{12},\ X_{21},\ X_{22}$ are the frequencies of the haplotypes ...
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140 views

Is Natural Selection like a Copy Editor?

I am stuck on a Homework Question. It says: Evaluate the following statement: “Natural selection works like a copy editor; it works only with what is already present in a population.” (Note: ...
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346 views

Why does the slope of parent-offspring regression equals the heritability in the narrow sense?

Background ---- Notations and assumptions ---- let $W_{ij}$ be the fitness associated to the genotype $AiAj$. $x$ is the frequency of the allele $A1$ in the population. The frequency of the allele ...
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115 views

Does recombination increase the additive genetic variance for fitness?

On this article, first column, eighth line of the introduction: By bringing together favourable alleles from different chromosomes, sex and recombination increase the additive genetic variance for ...
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37 views

What indices can we use to describe fitness landscapes?

We usually talk of smooth or rugged fitness landscape. Are there any (standard) indices to measure the "structure" of fitness landscapes? For example, one might consider the mean epistatic ...
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question about directional selection

Cattle breeders have improved the quality of meat over the years by which process? A) artificial selection B) directional selection C) stabilizing selection D) A and B E) A and C I know the answer is ...
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Fisher's Fundamental Theorem of Natural Selection

Ronald Fisher discovered what he, with humility, called the Fundamental Theorem of Natural Selection. This theorem says (in its modern terminology): The rate of increase in the mean fitness of any ...
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341 views

Why do genetic drift generates negative linkage disequilibrium?

The very first sentence of the abstract of this article are: "In finite populations subject to selection, genetic drift generates negative linkage disequilibrium, on average, even if selection ...
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550 views

Ka/Ks (dN/dS) analysis module for Python?

From this wiki article: In genetics, the Ka/Ks ratio (or ω, dN/dS), is the ratio of the number of Nonsynonymous substitutions per non-synonymous site (Ka) to the number of synonymous ...
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109 views

Why do animals only eat some parts of their food?

For example monkeys/apes only eat part of a fruit and then throw the rest. Cats (big and small species) only eat some parts of their prey and then they abandon it. Humans on the contrary leave as few ...
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157 views

Empirical evidence for Group Selection?

A controversial concept in Biology "Group Selection", has caused confusion and conflict amongst scientists since the since the mid 1990s. The more general realm of study is termed the "unit of ...
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118 views

Natural enemies boost deep evolutionary fitness?

"Two species that reduce one another's fitness on microevolutionary (short-term) timescales can increase each other's macroevolutionary (long-term) fitness" Opinions? Intuitive Examples: ...
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126 views

Assumptions of Hamilton's rule

Which elements of the following list are assumptions of the Hamilton's rule? Population structure (non-panmictic population) Additivity = Fitness of the heterozygote equals the mean of the ...
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Reformulation of Hamilton's rule

Who (and in which article) was the first to reformulate Hamilton's rule using the letters $B$ and $C$?. See below comments on this reformulation. Hamilton, in his 1964's article gave a mathematical ...
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416 views

Correlation between genome size and mutation rate?

Martin Nowak in his book "Evolutionary Dynamics" talks about a given correlation between genome size and mutation rate. What correlation does exactly exist between these two concepts? Is it a ...
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409 views

What does fitness really mean?

Fitness is certainly the most important concept in the theory of evolution. My question does not have to do with practical measures of fitness but with the theoretical definition of it. I am a bit ...
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2k views

What is the relationship between sexual and and natural selection?

In http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12701.html, they say: Thus, it seems that the diverse coloration in this species is promoted by both natural and sexual selection. ...
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220 views

Probability of Extinction under Genetic Drift

Here is the Wright-Fisher model of genetic drift: $$\frac{(2N)!}{k!(2N-k)!}p^kq^{2N-k} \Leftrightarrow \binom{2N}{k}p^kq^{2N-k}$$ where $\binom{2N}{k}$ is the binomial coefficient. This formula ...
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65 views

Who was the first to talk about evolvability?

"Evolvability is the capacity of a system for adaptive evolution." (source) There are several other definitions though: Who was the first person to use the word "evolvability"? Who was the first to ...
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136 views

The concepts of relatedness - Hamilton's rule and kin selection

Here is a quotation from this wikipedia page The relatedness parameter (r) in Hamilton's rule was introduced in 1922 by Sewall Wright as a coefficient of relationship that gives the ...
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367 views

Empirical evidence for species selection

Do we have any empirical evidence in favor of species (or lineage) selection? Do we know some cases that can only be explained (or seem to be only explained) by lineage selection? What are today the ...
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258 views

Is love biologically useful? [closed]

I thought about this statement a while ago: Natural selection sucks, it says those who love too much (or too many) will die the easiest and fastest. Sad but true. Only family (biologically of ...
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57 views

Phenoptosis, behavior evolved for good of species?

I was reading this and felt like the argument is being made that organisms die for the good of species. Isn't this nonsense? This especially bugged me: "'Age-induced, soft, or slow phenoptosis'" ...
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322 views

Does evolution take place universally?

Why does evolution (namely the evolution of primates into humans) take place both uniformly and universally on the earth? Why aren't there any creatures who have not taken the same evolutionary steps ...
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3k views

What evolutionary adaptations cause trees to grow tall?

I think there are some obvious costs for trees to grow tall. Carbon and other nutrients costs, maintenance cost, energy cost (for growing, to bring water (and nutrients) up to the higher leaves, ...
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3answers
650 views

Is there variation of AT/CG ratio along species?

Chargaff's rules say that the number of Adenine of the number of Thymine in a genome are equal (nA=nT) and similarly nC=nG. This makes obvious sense knowing that C binds to G and A to T. But what ...
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146 views

Model for fluctuating selection

Is there any mathematical model to predict the behaviour and long-term consequence of counter-acting selection at different time scale? For example, let's consider the bi-allelic gene A, with alleles ...
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608 views

Are there any scientifically based predictions or theories of future human evolution?

Reading this question of the stack exchange got me thinking. I believe human evolution is an ongoing process and will not stop. Are there any predictions/theories about the phenotypes and genotypes of ...