The theory by which mutations in the genetic code lead to differences from the previous phenotype that, should they be advantageous to an organism's survival to reproductive age, may be passed on to offspring.

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136 views

Correlation between genome size and mutation rate?

Martin Nowak in his book "Evolutionary Dynamics" talks about a given correlation between genome size and mutation rate. What correlation does exactly exist between these two concepts? Is it a ...
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25 views

Linkage disequilibrium with $n_l$ loci $n_a$ alleles

Linkage disequilibrium $\left(D\right)$ for two bi-allelic loci is defined as: $$D=X_{11}X_{22} - X_{12}X_{21}$$ , where $X_{11}$, $X_{12}$, $X_{21}$, X$_{22}$ are the frequencies of the haplotypes ...
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37 views

Reformulation of Hamiton's rule

Who (and in which article) was the first to reformulate Hamilton's rule using the letters $B$ and $C$?. See below comments on this reformulation. Hamilton, in his 1964's article gave a mathematical ...
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40 views

Effective population size and overlapping generations

From this book; If generations overlap, then the effective population size $N_e$ does not equal the population size $N$. I know mathematical formulations in order to find the effective population ...
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43 views

Selection on linked loci in a diploid population

Let’s consider two linked loci $A$ and $B$ that are both bi-allelic. In consequence, we have four different possible haplotypes $A_1B_1$, $A_1B_2$, $A_2B_1$, $A_2B_2$, which frequencies are $X_1$, ...
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70 views

Model for fluctuating selection

Is there any mathematical model to predict the behaviour and long-term consequence of counter-acting selection at different time scale? For example, let's consider the bi-allelic gene $A$, with ...
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63 views

effect of background selection on promoter regions compared to distant enhancers?

Has anyone looked at the effect of background selection on the levels of conservation of promoter regions compared to distant enhancers? Do promoter regions have a higher conservation due to ...
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98 views

Empirical evidence for Group Selection?

A controversial concept in Biology "Group Selection", has caused confusion and conflict amongst scientists since the since the mid 1990s. The more general realm of study is termed the "unit of ...
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37 views

Linkage disequilibrium, genetic drift and fitness variance

The very first two sentences of the abstract of this article is: "In finite populations subject to selection, genetic drift generates negative linkage disequilibrium, on average, even if selection ...
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7 views

Source of information on the evolution of aging/senescence

Do you know a good review (published peer-reviewed or an online course or whatever) that offers a good overview of all hypothesis explaining the various patterns linked with aging? I'd like this ...
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35 views

Why do animals only eat some parts of their food?

For example monkeys/apes only eat part of a fruit and then throw the rest. Cats (big and small species) only eat some parts of their prey and then they abandon it. Humans on the contrary leave as few ...
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39 views

Effect of natural selection on phenotypic variance

Short background Theoretically speaking, natural selection causes a decrease in genetic variance and because the environmental variance should remain unchanged, natural selection causes a decrease of ...