The theory by which mutations in the genetic code lead to differences from the previous phenotype that, should they be advantageous to an organism's survival to reproductive age, may be passed on to offspring.

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Linkage disequilibrium with $n_l$ loci $n_a$ alleles

Linkage disequilibrium $\left(D\right)$ for two bi-allelic loci is defined as: $$D=X_{11}X_{22} - X_{12}X_{21}$$ , where $X_{11}$, $X_{12}$, $X_{21}$, X$_{22}$ are the frequencies of the haplotypes ...
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Reformulation of Hamiton's rule

Who (and in which article) was the first to reformulate Hamilton's rule using the letters $B$ and $C$?. See below comments on this reformulation. Hamilton, in his 1964's article gave a mathematical ...
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Model for fluctuating selection

Is there any mathematical model to predict the behaviour and long-term consequence of counter-acting selection at different time scale? For example, let's consider the bi-allelic gene $A$, with ...
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effect of background selection on promoter regions compared to distant enhancers?

Has anyone looked at the effect of background selection on the levels of conservation of promoter regions compared to distant enhancers? Do promoter regions have a higher conservation due to ...
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Effective population size and overlapping generations

From this book; If generations overlap, then the effective population size $N_e$ does not equal the population size $N$. I know mathematical formulations in order to find the effective population ...
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Empirical evidence for Group Selection?

A controversial concept in Biology "Group Selection", has caused confusion and conflict amongst scientists since the since the mid 1990s. The more general realm of study is termed the "unit of ...
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Soft and Hard selection

Seems to me that these two sources (M. Whitlock, B. Wallace) use different definitions of soft and hard selection. M. Whitlock: Soft selection occurs when the relative fitness of an individual is ...
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Definition of Sexual Selection?

How do you define Sexual Selection (SS)? (One might want to subdivide SS into intra- and inter- SS to answer) Is SS clearly different from Natural Selection (NS)? Is SS nested within NS or are NS ...
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Is there an evolutionary explanation for depression?

Evolutionarily speaking, depression (both clinical depression and temporary sadness) is a curious phenomenon. Since being depressed is likely to increase the chance of a person with it to commit ...
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Source of information on the evolution of aging/senescence

Do you know a good review (published peer-reviewed or an online course or whatever) that offers a good overview of all hypothesis explaining the various patterns linked with aging? I'd like this ...
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Why do animals only eat some parts of their food?

For example monkeys/apes only eat part of a fruit and then throw the rest. Cats (big and small species) only eat some parts of their prey and then they abandon it. Humans on the contrary leave as few ...
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$F_{ST}$ and the genetic variance in metapopulations

From this video (21'15''), the speaker gives the following formulae in order to calculate the between and among populations genetic variance from the $F_{ST}$: $$V_{Among Pop} = 2 F_{ST}V_G$$ ...
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What is a sex-biased gene?

How do you define a male-biased gene and a female-biased gene as they are found in the abstract of this article.
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Effects of Genetic Drift on Linkage Disequilibrium

From what I understood of @Canadianer's answer here... Genetic drift randomly causes negative or positive linkage disequilibria, by changing allele frequencies through random sampling. Natural ...
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Effect of natural selection on phenotypic variance

Short background Theoretically speaking, natural selection causes a decrease in genetic variance and because the environmental variance should remain unchanged, natural selection causes a decrease of ...