The study of the structure and function of the nervous system and its components.

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Hodgin-Huxley model for a single neuron

I am viewing (through edX ) an introduction course to computational neuroscience. In the second lecture, the Hodgin-Huxley model is considered. I am going over some of the questions and have ...
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1answer
35 views

What determines the pathway of a neurological signal?

My question is about the neurological signals. In our body when a signal, for example a hearing signal from hair cells, is built, it goes through a lot of neurons and it passes a lot of synapses. I am ...
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713 views

Lumosity.com? Is it based on science?

I always see these Lumosity adds on TV, and I personally feel they are just trying to "sell me something". I did some layman's research(wikipedia) and read that "Studies of Lumosity's effectiveness ...
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1answer
58 views

Does learning increase the number of neurons in the brain?

I am attempting to understand neurogenesis related to learning. Does learning increase the number of neurons in the human brain? What would be some good scientific publications to read?
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35 views

How nerves interact with other cells? [closed]

I read in a book by Mick O'Hare, that injuries inflicted by electric current are caused by tension of your muscles. Is that explainable only with physics or nerves really use electrical signal as ...
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1answer
82 views

What are dreams, biologically?

Falling asleep or states of subconsciousness does not stop the mind from making its own fictional images. These seem like sensations just like those received from human eyes. But, how do we define ...
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2answers
54 views

Introductory book in genetics? [duplicate]

I am working in the field of neuroscience with a background in computer science. I try to find new ways of analyzing brain imaging data (mostly MRI, EEG, MEG, fMRI) with modern machine learning ...
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1answer
41 views

Is the autonomic nervous system only activated by internal stimuli?

My professor claims that the autonomic nervous system is only activated by stimuli from organs but I really feel like I've read that it can be activated by outside stimuli, although I'm not sure what ...
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1answer
20 views

Why do negative ions flow into a cell in an inhibitory synapse, even though a neuron has a negative resting potential?

In my spare time I have been reading an introductory Psychology textbook and this question came to my mind after reading about action potentials. I have no previous knowledge in chemistry so if I do ...
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107 views

Why does the human brain not overfit when training at some task?

One of the problems that occur during (artificial) neural network training is called overfitting. The error on the training set is driven to a very small value, but when new data is presented to ...
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1answer
97 views

Do rare earth metals actually repel sharks? [closed]

Stroud claims that sharks are effectively repelled by the use of rare earth metals in the water. There has even been a patent issued by the same author for rare earth-wrapped fish hooks to reduce the ...
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4answers
2k views

Why do smaller mammals move intermittently?

I was watching a nice little video on youtube but couldn't help but notice how snappy smaller animals such as rats and chipmunks move. By snappy I mean how the animal moves in almost discrete states ...
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975 views

What kind of memory is “keyboard/keypad memory”?

I work in IT and I have observed many people who cannot remember their iPhone passwords or computer passwords off the top of their head. However, if presented with a keyboard or a phone with a ...
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1answer
35 views

Can nociceptors die because of too much mechanical stress?

In martial art people hit their body (e.g., with small bean bags) to become more insensitive to pain. Can the sensory neurons die during this procedure? I think this is just an urban legend. Instead, ...
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1answer
54 views

Do both Carbamazepinum and Lamotriginum increase glutamate threshold?

I have in my notes that: Carbamazepinum increases threshold for glutamate Lamotriginum delays release of glutamic acid I would like to simplify these sentences into a single line. I would like to ...
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1answer
81 views

What would be required to evolve an animal (non-human) brain to obtain human-level cognition? [closed]

Could any animal subject to the right conditions evolve human-level intelligence? Suppose that an artificial intelligence (AI) decided to artificially evolve a population of octopus (don't ask why, ...
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1answer
78 views

Why can action potentials not be initiated at dendrites?

Why are action potentials not initiated at dendrites, although dendrites are the first to receive input from the presynaptic cell? In fact, excitatory postsynaptic potentials (EPSPs) at the dendrites ...
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22 views

classical conditioning paradigm for hippocampal learning

I wanted to know what a suitable classical conditioning experiment would be to analyze learning and memory capabilities in rodent models with respect to hippocampal long-term potentiation. For ...
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1answer
56 views

Relationship between toxicity of drugs and negative effects on brain

Are psychoactive drugs with lower lethal doses more neurotoxic (more damaging to the brain)? For example, tetrahydrocannabinol (one of the active components of cannabis) has a much higher lethal dose ...
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1answer
65 views

Why does a lack of sleep degrade my balance?

For years, I've noticed that the day after a night of poor sleep (4 hours or less), my balance noticeably degrades. For instance, while walking 20 feet to the coffee maker, I might stumble into the ...
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1answer
30 views

Can the Hebbian theory apply to Inhibitory Neurons

If I understand the basic Hebbian theory, when a neuron fires a pulse to another neuron and this pulse causes the target neuron to fire then the delta energy sent from the initial neuron to the target ...
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34 views

Neuroscience behind the crash

After experiencing things like stress, intense exercise, or using drugs such as caffeine and amphetamine, subjects often assume a depressive and lethargic state afterwards, known as a "crash." What is ...
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1answer
52 views

Oxygenated hemoglobin in MRI

I have read the following sentence: Because this oxygenated hemoglobin is unaffected by magnetic fields, the response RF signal returned to the fMRI scanner is stronger when there is more ...
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0answers
21 views

Hypoglossal nerve location

I kind of know where the hypoglossal nerve is located when I look at the diagram but I'd like to know how far is the nerve from the skin and where is the closest area to the skin before and right ...
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1answer
55 views

What recovers normal polarisation after hyperpolarisation?

I have been taught that a Na+/K+ pump helps to recover normal polarisation after hyperpolarisation in neurons. I could not find out how it does that, since I've also been taught that such a pump moves ...
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2answers
59 views

Mechanism behind negative conductance of ion channels

I am struggling to understand negative conductance shown on I-V curves on ion channels. Mechanistically, negative conductance means that inward (or outward) current increases when voltage across ...
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46 views

Neural coupling between Pinsky-Rinzel (reduced Traub) neuron with a Wang-Buzsaki neuron?

I have read two papers related to modeling neurons. The first one is the paper by Pinsky and Rinzel and the second one by Wang and Buzsaki. The first mentioned neuron model is a excitatory neuron ...
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58 views

Why can we control our breath rate but not our heart rate? [closed]

Even though we cannot survive for more than few minutes if we stop breathing or if our heart stops, why is it so that our heart beat is controlled involuntarily while breathing can be voluntarily ...
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1answer
81 views

Oscillatory electrical system using a chain of neurons

Many daily activities that we perform are result of inbuilt oscillatory circuits in our body. For example walking, breathing, heart beat, blinking, etc. The coding and decoding of stored memory also ...
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1answer
108 views

Neuroscience of mathematicians

I've tried to google this but everything that comes up are things like "mathematical neuroscience" rather than the other way around. Specifically, I'm interested in the workings of a mathematician's ...
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1answer
54 views

Does breathing air containing 3% carbon dioxide gives you a headache?

As far as I know, breathing air containing relatively high levels of CO2 may get you a headache. I also know that CO2 level in the fruit bodies of peppers can reach levels as high as 3% at certain ...
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1answer
70 views

Neuronal coordinates of C.elegans

Is there a list of neural coordinates for C.elegans? I need it to build a 3D model. Update: What is available at the moment is: full connectome for example, at openconnectome; neuron description ...
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2answers
162 views

Could an action potential produce few or more neurotransmitters based on the stimulus received?

I reckon that if you would be able to widen the AP width, it would produce more neurotransmitters in that larger time interval. Is that correct? Or does the neuron have a standard amount of ...
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25 views

Regarding cryonics, why can't you freeze a living body and then thaw it later, fully functional?

Cryonics is very popular in science fiction today, as a method of preserving animals, including humans, for long time storage and thawing the tissue later in the future. What is the difficulties with ...
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39 views

Case Study and speculations of Edward Mordake

I am very interested in the case of the man named Edward Mordake who lived in the 19th century. In particular, he had two faces. If you have not heard of this man, please, search this up as there are ...
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1answer
40 views

Is the motor cortex identical to the sensorimotor cortex?

As far as I understand, the primary motor cortex (M1) and primary sensorimotor (SM1) are notations for the same cortical area in the brain. Am I right that there is no dedicated motor cortex, and that ...
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42 views

Further progression with neuroscience education [closed]

Question for you I hope this is in the right area and all if not please advise on where to put it, Having taken biological neuroscience for a year now as a masters program I feel like I want to go ...
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1answer
50 views

How does a change in the potential across a neuron's membrane get turned into a signal that is sent down the axon?

I understand How a signal is propagated down the axon. How the membrane potential of a neuron changes during the course of it's "firing". But I don't understand how physically the change in ...
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2answers
144 views

Are all action potentials the same shape and amplitude when graphed with respect to time?

The most common visualization of an action potential is a graph of the difference in membrane potential (y axis) at a particular time (x axis). According to my textbook Cognitive Psychology by E. ...
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1answer
59 views

How does a microelectrode work?

On Wikipedia, the entire microelectrode page states only the following: A microelectrode is an electrode of very small size, used in electrophysiology for either recording of neural signals or ...
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1answer
78 views

How precisely can we sense temperature differences?

We have thermoreceptors, thus we can sense temperature (both warm and cold). I'm interested in the sensitivity of our thermoreceptors - What is the smallest temperature difference that we can sense? ...
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135 views

Is it possible for a human to wake up in a wrong way?

There's an old folk saying that goes like "He got out of bed on a wrong foot" - to indicate that the person's day is going poorly because of the way that person woke up. Is it is possible for a human ...
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1answer
33 views

Safe parameters for external nerve stimulation using electrical impulses

Introduction I've recently stumbled upon David Eagleman's TED talk on the concept of sensory substitution and addition. Being the most inspiring thing I've seen on the internet for the last few ...
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39 views

Behavioral change in dolphins during different hemispheres activity periods?

It is known that dolphins never sleep in the sense that we do, instead they have one hemisphere of the brain sleeping while the other one is awake. I wonder, do they show observable changes in ...
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1answer
76 views

How pain can stimulate the vagus nerve

I'm trying to find out why a prompt, severe, short pain is causing a stimulation of the vagus nerve. What could the physiological explanation be? Is that because the pain is triggering the ...
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4answers
891 views

Is there any way a human could whistle and be unable to speak?

Is there any situation anatomically, where a human could understand the speech of others perfectly, without any capabilities of speech themselves, but would retain the ability to whistle with a tune? ...
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1answer
62 views

Why are skin tactile receptors considered to be phasic receptors?

A phasic receptor by definition is one that quickly adapts to change. In terms of neuron firing, this means that it does not trigger another firing because the receptors are used to the stimulus. But ...
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2answers
124 views

Is there a biological neuron that spikes in response to hyperpolarizing currents?

As some background I've been building Electrophysiological models of neurons, and in the process stumbled upon a model, that in all respects is biologically plausible, but has a bizarre property I ...
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26 views

Immediate Early Genes during sleep

In Neuroscience 3rd ed by Bear et al. on page 607, immediate early genes are described as related to changing synaptic strength, yet have decreased expression during sleep. The explanation given is ...
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99 views

What is the mechanism behind tinnitus?

I seem to have come across two contrasting explanations for tinnitus induced by loud noises- i.e. damage to the hair cells in the cochlea. On the one hand, I have read that damage to the hair cells ...