The study of the structure and function of the nervous system and its components.

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Definition of general anesthesia

To quote Goodman & Gilman : An alternative way of defining the anesthetic state is to consider it as a collection of “component” changes in behavior or perception. The components of the ...
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Metabolic activity postmortem

I read some papers about studies on metabolism in post-mortem tissues in human, but I do not exactly the reason about why our brain continues to have activity after death.
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Do repetitive movements on EEGs show up as discernible patterns?

Here is a typical EEG reading: If I am connected to an EEG, and am sitting perfectly still, and then begin doing some repetitive motion, say, 10,000 times, will we see discernible patterns emerge ...
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What causes the range of severity of neurological deficits in Down's syndrome?

It's known that the severity of symptoms caused by a trisomy 21 varies from individual to individual. Part of the explanation for this range of severity is the finding that 94% of Down's syndrome ...
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24 views

Why is the autonomic nervous system divided into parts? [closed]

Why would it be advantageous from an evolutionary perspective to develop parasympathetic and sympathetic systems?
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82 views

Resting membrane potential: K+ concentrations and charges on inside and outside of the neuron

According to this site, there is a greater concentration of K+ ions inside the cell than outside. The following screenshot, taken from this website, supports this statement. However, I don't ...
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Confusion about resting membrane potential and the Na/K pump [duplicate]

To this day, very few people and sources have been able to clear up my confusion about resting membrane potential and how it is maintained. It seems like this is one of those topics that few people ...
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What is the reason for fear induced defecation?

I started to handle mice for my job and noticed that they tend to defecate and/or urinate when they are scared. The fear is induced by me, because I need a long time (due to inexperience) to grab the ...
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Brain wave and motor movement correlation

I am trying to better understand which brain waves are generated when the motor system (arms, legs, muscles of any kind) are activated. According to Wikipedia, several types (Beta, Gamma, Mu) appear ...
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76 views

How does the mechanism which controls blood pressure in the brain work? [closed]

I've heard that the blood pressure in the brain is organised by a special mechanism. What is that and how does it work?
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Why can't we see in low light if staring long enough?

For me it seems reasonable that if I kept my gaze on a fixed point in a room with low light, a progressively brighter and better picture would appear before my eyes, just like a camera can see in the ...
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104 views

Synaptic pruning and selective elimination during adolescence

How does Synaptic pruning occur during pre-adolescence, adolescence and post-adolescence, after there is blooming overproduction of synaptic connections until the years of late childhood, and how does ...
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117 views

All-or-nothing-law: law or general principle?

The all-or-nothing principle indicates that a nerve cell fires at maximum potential or not at all, based on a threshold on the stimulus. Is this a statement which is always true, or only mostly-...
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68 views

What determines the shape of the center-surround receptive fields of retinal ganglion cells?

The wikipedia article about receptive fields of visual system tells us the following: The receptive field is often identified as the region of the retina where the action of light alters the ...
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41 views

What kind of changes “stays” in the neuron after the nervous impulse happened?

I often see in neuroscience textbooks about how the brain controls everything in the body with different tracts and etc, and it seems that information is always being transmitted, like there's no ...
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44 views

What is 'noise'?

In both my psychology, biology and neuroscience classes, professors are constantly talking about 'noise'. For instance, our perception is limited due to 'sensory noise' in our neurons. I am utterly ...
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45 views

How do Binaural Beats Work?

We have a project on different ways of relaxation. One way I found out was binaural beats. Could anyone please tell me how they work. You guys are masters when it comes to simplifying things! All I ...
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36 views

Are axons capable of endocytosis?

There is evidence for the uptake of toxic substances like prions from the cell bodies of neurons via endocytosis. There is also evidence for prion deposition in white matter. But I haven't been able ...
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60 views

How difficult is it to make a shRNA/miRNA/siRNA to silence/knockdown NaV1.7 voltage gated sodium channels in humans?

There have been various research projects that experimented with shRNA/miRNA/siRNA to specifically silence/knockdown NaV1.7 voltage gated sodium channels in small animals like rats & guinea pigs. (...
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51 views

Is HSV-vector-mediated miRNA expression in dorsal root ganglia stable?

My question is on the following article: "Reduction of voltage gated sodium channel protein in DRG by vector mediated miRNA reduces pain in rats with painful diabetic neuropathy" My question is, do ...
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Are 2 eyes necessary for 3D vision?

To start off: I'm not a biology student, but a computer science major It has always been my understanding that humans have 2 eyes so that we can have 3D vision: the left eye see more of the left side ...
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19 views

Are cortical columns restricted to somatosensory cortical sections?

From this previous question, it seems like evidence for the minicolumn organisation of the neocortex seems to be primarily based off observations around the sensory parts of the cortex, such as the ...
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59 views

Why is stimulation of nerve tissue with a negative pulse called “cathodic” stimulation?

By definition, the cathode is defined as the terminal through which current exits a polarized device. But in the context of neuromodulation, such as spinal cord stimulation, deep brain stimulation, ...
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How are individual neuron firing rates characterized?

I'm reading this paper that the Human Brain Project published in Cell and I'm confused how they recorded the firing rates shown in the firing below: In the publication, they mention that they use ...
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49 views

How does the brain train its neural network?

One question that came up learning how artificial neural networks are working was how the brain can train its neural network? When we say we have an artificial neural network, the problem behind it ...
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How does a real brain actually learn? [closed]

In biology class we've learned that neurons are connected. If two or more neurons interact with each other often, then the connection gets stronger and stronger, and new connections may form. But if a ...
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How are targets formed for axon growth cones (CNS)?

Axons have growth cones which find a route to their target using multiple methods (guidepost cells, attraction to target, etc...). My question is, what is the process that actually forms the target? ...
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Understanding the brain: how are neurotransmitters released in the brain?

I have a basic knowledge of how neural networks work. A potential difference is created that forces sodium, potassium, chloride, and calcium ions to flow which carries an electrical signal to the end ...
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81 views

How can neuronal signals faithfully be reproduced by scalp electrodes?

There is a skull barrier (and possibly other layers too) between the brain and the scalp. I have seen people trying to extract EEG signals from the scalp by connecting electrodes and interface it to ...
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27 views

Synapse formation [closed]

I am trying to learn about neuronal synapse formation, but the literature is intimidating to someone with little background knowledge. I am interested in synapse formation in both human adults as ...
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72 views

Reseach on feeling pain of other people

I'm more of a tech than bio kind of guy, but I have read and learned a lot alongside of my girlfriend's education. Which is very interesting!! Currently I want to investigate : people claiming to ...
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Does neural network in brain form cycles?

In other words is it possible for dendrite of neuron A to be connected with axon of neuron B and at the same time dendrite of neuron B to be connections with axon of neuron A (or similarly for any ...
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I know how to solve these equations, but I'm not sure what t' represents?

I am investigating the Wilson Cowan neuron population model, and I can follow most of it, but I'm not sure what is meant by t' in the equation for proportion of neurons in the refractory period. The ...
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64 views

Development and function of spindle neurons

In his book How to Create a Mind author Ray Kurzweil makes some claims about spindle neurons that he provides no source for. Concretely he states that spindle cells: Are Involved in handling ...
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Dreaming after passing out

I'll have few questions about passing out and dreaming. English is not my native language, and my biology knowledge is very limited. So bear with me. What exactly is blackout? (in a really simple ...
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What effect is seen when the extracellular concentration of sodium is increased? [closed]

I can't seem to figure out how this would effect the cell since sodium is not very permeable.
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298 views

Why do nerve cells convert electric signals to chemical signals?

One would assume that a faster response time in the nervous system would be beneficial. However, nerve cells have to convert electrical impulses to chemical signals and cross a synapse. Why didn't ...
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167 views

How does the brain recall information?

In computers, finding a single word is realized through serial attempts across all available connections to find a specified target. How does the brain solve this? How does the whole process, from ...
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156 views

Is there a difference between visual sensation and imagination in the brain?

How substantial is the difference between the neural signal associated with seeing an image and the imagination of that image? Surely, it can not entirely copy the pathway from the sensory organs to ...
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At what point during an action potential are the sodium potassium pumps working?

I'm trying to understand how all of the potentials during an action potential are created. My question specifically is about the sodium potassium pumps, however I would also be grateful if someone ...
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What stimulates a nociceptor?

For instance, when pressure is applied to the skin, what determines how much pressure results in nociceptor stimulation. And when a sharp object pierces the skin, why is pain, rather than simply touch,...
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125 views

How are neural networks encoded in the DNA? [closed]

The central nervous systems as well as the brain->muscles and sensory cells->brain nervous pathways, need to be precisely wired for life to be possible. Moreover they are wired almost exactly the same ...
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How do mindfulness meditation and lucid dreaming relate?

It has occurred to me that mindfulness meditation and lucid dreaming are probably closely related. I'd like to know how brain activation patterns and other biological parameters compare between the ...
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What neurons make up the CNS?

I generally see it written that there are three types of neurons, classified by projection: (1) sensory neurons, (2) interneurons, and (3) motor neurons. Now, in the CNS, I don’t think there would be ...
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Is this “Sympathetic fight response” axis accurate?

Peripheral sensory cell > Preganglionic cell > Dorsal root ganglia cell in the ''Sympathetic chain'' > Ventral root ganglia cell in the ''sympathetic chain'' > Post-ganglionic cell that activates an ...
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Why do we like music?

Music is, of course, just a sequence of sounds. Sounds are vibrations in the air, which our ears detect. So why do we find certain sequences of sounds to be appealing? What makes us want to hear these ...
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Is there any evidence to suggest that exercise reduces the side effects of caffeine?

I heard a friend say: I'm not drinking coffee this week. My body can only process the caffeine if I run at least 15km a week. I found this claim fascinating - that exercise temporarily ...
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Does music enhance neural activity/cognitive or cerebral function, or is it just mania? [closed]

I always find myself drew upon curiosity whilst studying, to whether certain types of music are or are not, effecting me in a sense of cognitive ability. Take a fantastic piece such as, Mozart's, ...
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What is the speed of neurotransmitter release and receptor binding in a neuronal synapse?

Obviously neural signals travel at extremely high speeds, but I'm wondering how much that speed is affected by the release and binding time of neurotransmitters. If my sources are correct, a well ...