The study of the structure and function of the nervous system and its components.

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Which Receptors are Involved in the antidepressant effects of SSRIs?

From what I've read the major receptor subtypes involved in the antidepressant effects of SSRIs are: 5-HT1A 5-HT2C 5-HT3 5-HT6 Please cite journal articles to back up your claims, I don't want any ...
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24 views

Stress regulation in mosquitoes

I was just trying to understand how in insects, specifically mosquitoes does the process of emergency responding, stress regulation take place? Or in simpler words how are flight, fright and fight ...
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1answer
160 views

Are inflammation and anxiety connected?

I've been reading a curious paper about the use of cannabis, and one of the passages piqued my interest: There’s also been a lot of work done on another constituent of marijuana, cannabinoid, ...
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60 views

Missing cells from immunopanning

Why do I not have any cells left in my positive panning plate after transferring from the negative panning plate during immunopanning? I am trying to purify retinal ganglion cells from postnatal rats ...
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9k views

What are the functions and differences between axons and dendrites?

My textbook doesn't do a very good job of pointing out what the differences between the two are. It basically mentions axons only in the same breath as the synapse (that synapses are the endings/tips ...
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115 views

Epinephrine vs. Adrenaline

Both names are widely used, with what appears to me as a slight prevalence of “epinephrine” in scientific literature and an overwhelming prevalence of “adrenaline” in popular media. Are there any ...
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68 views

Organisms with the most extreme sensory capabilities? (sight, smell, sound) [closed]

Background It is quite mind boggling to imagine what it would be like to be missing sight, sound, touch, smell, taste etc. Question Which organism holds the record for most extreme sensory ...
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238 views

Is there a maximum pain threshold?

Is there a maximum threshold of pain a Human can experience, beyond which point there is no noticeable difference? I ask this question in part to better understand the definition of pain and its ...
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2k views

Do neurons secrete multiple neurotransmitters, or just one type?

I know that neurons communicate between each other by filling the junction between dendrites with neurotransmitters. What interests me is if a single neuron only works with one type of ...
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226 views

Are there any types of cancer that cause neurons to divide?

After birth neurons generally do not divide. But is there any specific type of rare cancer or tumour where neurons divide? And if there is such a cancer, then how is it possible for a neuron to regain ...
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8k views

How does the brain's energy consumption depend on mental activity?

What is the impact of mental activity on the energy consumption of the human brain? I am most interested in intellectually demanding tasks (e.g., chess matches, solving a puzzle, taking a difficult ...
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58 views

The Operation of tuning in the S1 layer of ventral model

According to my previous question in ventral Stream pathway and architecture, I want now to get a brief example about how the S1 layer is constructed. In other words, how all the simple units are ...
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1answer
86 views

What will happen if we expose the brain to an intermittent light?

If a brain is exposed to an intermittent light are specific areas going to fire? If yes, which of them? Is there any experiment about this?
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81 views

What in neurons and their connections changes during the process of learning?

I'm not sure if this question belongs more in physics or biology (or maybe even computer science)... but biology seemed to fit more. What changes in the state of our brains when we learn things? ...
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65 views

Radial Basis Function Network (RBF Network)

In the Wikipedia article on radial basis function network, I didn't understand what was meant by "center vector for neuron i", in other words "center of the RBF units called also prototype".
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1answer
188 views

Understanding Membrane / Resting Potential from the perspective of ions?

From wikipedia article RESTING potential: "there is no actual measurable charge excess in either side. That occurs because the effect of charge on electrochemical potential is hugely greater than ...
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2answers
585 views

How is temperature sensed?

Can anyone summarize the mechanism by which when an object of a given temperature is placed in contact with, say, the skin on a human fingertip, the average speed of the particles of the object is ...
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49 views

Nocioception (pain perception) in subcutaneous tissue

There seem to be no nocioceptors (pain and temperature sensitive nerve endings) in subcutaneous fat. there are nocioceptors and other receptors in veins running through fat, but these can be avoided. ...
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3answers
181 views

Mechanical cause of loss of consciousness

Consciousness is an electrical and chemical interaction in the brain, caused by neurons firing and chemical interactions. How does a mechanical "force" cause this to stop working? i.e. How does a ...
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1answer
207 views

Ventral stream pathway and architecture proposed by Poggio's group

Please can you give me a very brief explanation about all functions in the ventral stream architecture summarized in this figure: This figure is from Serre et al.'s A quantitative theory of ...
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3answers
144 views

Why are things conscious?

I've been referred to here from http://philosophy.stackexchange.com/questions/8052/why-are-things-conscious. Could you guys help out? Here's the question: What is the reason for animals or more ...
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9k views

How reversible is decerebrate posturing caused by brain stem damage?

This is a follow-up question to How likely would Abraham Lincoln be to survive his wounds today? You don't have to see a CT scan or autopsy to know if the brainstem is injured (directly or ...
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25 views

How is saltatory conduction faster than conduction of unmyelinated fibers? [duplicate]

It's always the same explanation that currents are able to "hop" along Ranvier nodes instead of passing continuously along the axon making saltatory conduction more efficient than continuous ...
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1answer
53 views

Number of MHCs in neurons

I have read that neurons have proportionately less MHC molecules than other cells of the body. What is the advantage of this?
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282 views

What happens in your brain when you receive information which causes you to bristle?

I'm talking about moments when you watch a film and you bristle, or when you listen to music, etc. What kind of neurotransmitter flow changes?
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179 views

Zombie Ant Fungus?

Ophiocordyceps unilateralis is a parasitoidal fungus that alters the behavior of the infected. Source: Wiki page. How is the fungus able to alter the behavior of the infected to such specfic ...
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1answer
174 views

What happens in the synapse when cocaine administration occurs in the human brain

As far as i know when you accept cocaine in your blood some cocaine molecules reach some synapses in your brain and fill some Reuptake tunnels preventing the cell to simply "do not know that fired ...
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3k views

Why do neurons die so fast without oxygen and nutrients?

Some human tissue can survive without oxygen a couple of minutes, even hours. Why are the neurons are so "weak" and depends so much on oxygen and other nutrients and cannot live without them for ...
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2k views

Why is saltatory conduction faster than continuous conduction?

How does spacing apart sodium and potassium channels allow the action potential to travel faster down the axon? This is the reason always cited for saltatory conduction and myelination, but my mental ...
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1answer
429 views

What is 'calcium conductance'?

What is the meaning of calcium conductance in ion channels. I encountered this in the following text: It was established that the µ and δ opioid receptors open potassium channels, which results ...
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1answer
232 views

L1 - L5 layers of the brain

I have read in some papers about the layers L1-L5 of the brain (e.g. in this paper). I could not find a definition of these layers. I have found information about the layers V1-V5 in the visual ...
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1answer
51 views

Does sympathetic nervous system acts bilaterally for pupil dilation or other two sided organs?

The question might seem weird. Does sympathetic nervous system acts 'bilaterally' meaning if you shout to a person's left ear a loud noise (e.g. by headphones), will it activate sympathetic system ...
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2answers
198 views

Why do the brains of cocaine-users shrink faster than the brains of non-cocaine users?

http://news.sciencemag.org/sciencenow/2012/04/cocaine-may-age-the-brain.html?rss=1 Cocaine-dependent individuals showed a significantly greater-than-normal age-related decline in gray matter in ...
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2answers
104 views

Inverse of dopamine reuptake inhibitor?

The wikipedia article on the dopamine transporter gives examples of some drugs whose effects are mediated by the inhibition of the dopamine transporter, such as cocaine and amphetamines. Are there ...
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3answers
229 views

What exactly is the neural receptive field?

Neural receptive fields map the spatial or temporal distribution of the data to individual neuron excitation, if I understand correctly, but I do not understand if receptive fields (especially in the ...
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33 views

What Role Antagonists Play in the Study of Drugs?

I am pretty unfamiliar to pharmacology. I'm doing a research on drug abuse, particularly opioids' mechanism of action. I encountered several times evidences that come from studies using antagonists ...
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1answer
105 views

What light intensity determines the start/end of a photoperiod in humans?

I'm reading this article, which discusses the influence of Long Photoperiod (LP) and Short Photoperiod (SP) on melatonin production: HIOMT drives the photoperiodic changes in the amplitude of the ...
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1answer
115 views

What areas of the brain are involved in doing arithmetic operations?

Do neuroscientists already know what areas of the brain are involved in mental calculations? Has any fruitful research been done on that or not yet? Do you think that if we understand what areas of ...
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1answer
92 views

What triggers creative thought in humans?

Creativity, innovation and ideation. Is there something in the brain that makes the brain think that way, as opposed to "normal baseline". What triggers creative thought in humans?
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170 views

If a dead snake reflexively attacks itself, why does it not always attack itself?

Recently there has been this video going around of a snake that had been decapitated. Its body swung around to the decapitated head and the head attacked the body on "reflex". Now we know that most ...
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57 views

Does pain scale with mammal mass?

Some biological features scale with the animal mass (see previous Q&A). Assuming the same concentration of nociceptors on the skin surface, I'm wondering how painful a 1 cm wound will be ...
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1answer
1k views

Neuromediator, Neuromodulator, Neurotransmitter?

Of these three words, perhaps Neurotransmitter is the most obvious. I took a look at Wikipedia page for Neuromodulation and found that this is pretty similar to Neurotransmitter too. I guess ...
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62 views

What decides the position of the node of Ranvier?

The oligodendrocytes makes the myelin sheath in CNS and schwann cells make it in PNS. What decides where the oligodendrocyte or Schwann cell will attach and start forming myelin sheath? Is it ...
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118 views

Molecules and human memory

Has it been demonstrated that the memory of human brain is just connections between neurons, not "long" molecules such as RNA or proteins?
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1answer
159 views

If people with colorblindness lack one type of cone cells, shouldn't they be unable to recognize one particular color?

The 3 types of cone cells in normal humans allow them to view 3 types of colors and any color made from mixing and matching those 3. So, 2 types of cone cells should only allow to view just 2 types ...
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2answers
780 views

What is a cortical circuit?

I have read about cortical circuits in the context of connectomics (e.g. any example here) and computational neuroscience (e.g. any example here), but a simple Google/Wikipedia does search not show an ...
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1answer
105 views

Is Nerve Growth Factor (NGF) commercially available?

I'm curious if NGF, or Neurotrophins in general is available commercially. Can I order it online? If not, what are the medical/biological reasons. Does it breakdown quickly after synthesis/capture? Is ...
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1answer
48 views

Is there a type of amnesia that seperately affects long-term memory?

Is there a medical condition that affects the long term memory, but leaving the short-term and working memories totally or fairly intact?
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2answers
831 views

Physiological indicators of happiness and well being

If I understand it correctly, levels of serotonin in the brain can indicate if a person is happy. What other physiological measures indicate happiness or well being for a humans? I am looking for ...
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1answer
79 views

Eye Brain Mapping

If our eyes are separated by some kind of full proof barrier/isolation, is it possible that our brain can picture/visualize two different pictures at a time? How the brain will function in this ...