The study of the structure and function of the nervous system and its components.

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What is the biological basis for the perception of time?

How is the "time axis" of memories encoded in the brain? I guess the time of the event could be "stored" with each event, but how is this translated into neurons etc.?
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169 views

What is the purpose of the adrenal medulla?

The adrenal medulla is less of a 'real' endocrine organ like the others in the endocrine system and much more an extension of the sympathetic nervous system. In fact, its chromaffin cells are modified ...
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70 views

Criteria for compound action potential thresholds

As opposed to action potential thresholds (which are binary yes/no events), electrophysiological thresholds of compound action potentials are arbitrary. Mostly a certain noise level is picked and when ...
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296 views

How does the brain know where a signal came from? What is the addressing system

I am an electronic engineer so I am thinking about this from an electronics outlook. How does the addressing system work, As I see it, the nervous system is small parallel branches attached to larger ...
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183 views

Does playing music during sleep actually suppress rather than rouse the brain?

I've long been interested in the effect of music/sound on dreaming, and even built 2 apps that play music during REM period. Now I'm looking at this article about FMRI studies of a sleeping brain, and ...
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72 views

Missing cells from immunopanning

Why do I not have any cells left in my positive panning plate after transferring from the negative panning plate during immunopanning? I am trying to purify retinal ganglion cells from postnatal rats ...
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2k views

What part of the brain controls depth perception?

Specifically the part of the brain that does depth perception based on binocular vision. I have searched all over the web and have turned up nothing. Is it the same part of the brain that processes ...
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384 views

Does frequency of eye blinking reveal anything about human biology/nervous system?

I'm looking at an output of a single dry sensor EEG headband with the sensor positioned above left eye. As a side effect of it's placement, the device picks up eye blinks, and some eye motion as ...
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52 views

How does Serotonergic (5-HT2A mediated) Psychedelia work?

How does serotonergic (5-HT2A specific) psychedelia work? I've read that there are some theories that it might involve the induction of a glutamate release in certain regions of the brain involved in ...
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331 views

Effects of exercise on the brain

I am well aware of the phenomenon of neurogenesis induced by exercise, as well as the dopamine release that results from exercise. I am really interested in neuropsychology and the effects of exercise ...
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108 views

What light intensity determines the start/end of a photoperiod in humans?

I'm reading this article, which discusses the influence of Long Photoperiod (LP) and Short Photoperiod (SP) on melatonin production: HIOMT drives the photoperiodic changes in the amplitude of the ...
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809 views

Is there a relationship between Melatonin, Norepinephrine and depression in humans?

I'm reading a booklet on melatonin published in 1996, titled "Melatonin and the Biological Clock". This particular paragraph caught my attention and I would like to better understand what it means: ...
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42 views

Case Study and speculations of Edward Mordake

I am very interested in the case of the man named Edward Mordake who lived in the 19th century. In particular, he had two faces. If you have not heard of this man, please, search this up as there are ...
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82 views

Is the six-layer cortex model of the mammalian cortex still the most accepted model?

I've been reading a bit about the different layers of the cerebral cortex and its clear that certainly not every region of the cortex has the same number of layers. Thus, the idea that every region ...
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119 views

If D1 receptors stimulate adenylate cyclase (through GPCRs) and D2 receptors inhibit it, then why do mutations in both have similar effects?

D1 and D2 both refer to specific types of dopamine receptors. I'm sure it has something to do with the fact that the D1 receptors are in regions different from D2 receptors. I know that adenylate ...
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66 views

Why does a lack of sleep degrade my balance?

For years, I've noticed that the day after a night of poor sleep (4 hours or less), my balance noticeably degrades. For instance, while walking 20 feet to the coffee maker, I might stumble into the ...
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784 views

Why do neurones use chemical signalling at synaptic junctions?

Problem. When a neurone fires, it sends an electrical signal that jumps down the axon via the nodes of Ranvier very rapidly. At a synaptic junction, chemical brownian diffusion signalling with ...
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165 views

Could an action potential produce few or more neurotransmitters based on the stimulus received?

I reckon that if you would be able to widen the AP width, it would produce more neurotransmitters in that larger time interval. Is that correct? Or does the neuron have a standard amount of ...
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295 views

Where do butterflies sleep?

Do butterflies (insects) sleep, and if so, where?? I have googled for information but didn't get an exact answer.
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172 views

Membrane potential after exposure to glutamate

Neurons were kept in a physiological solution. During the resting phase, the membrane potential in the axoplasm of neurons was negative compared to the extracellular space and a potential ...
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144 views

What are the factors that control the speed of propagation of neuronal signals?

If we consider an analogy between a wire and a neuron there may be some resemblance between the factors controlling the data flow rate. For example the increased width of wire leads to decreased ...
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581 views

Action potential and sodium channels

In this video on electro tonic potential, the tutor says that when the potassium channels open the potential drops from +40mV to -80mV, where the sodium channels have already closed at +40mV. Now in ...
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159 views

How is information sent from limbs to the brain exactly?

Say you have a needle, and you poke a very specific area on your left thumb. A signal gets sent from that nerve up your spine and into your brain. How does the brain know exactly where this signal ...
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80 views

Biological advantage of electric synapses

Electric synapses are synapses that do not process information but simply foward one action potential from one neuron to the next. There are no neurotransmitters, no inhibitory and exitatory ...
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2k views

Neuromediator, Neuromodulator, Neurotransmitter?

Of these three words, perhaps Neurotransmitter is the most obvious. I took a look at Wikipedia page for Neuromodulation and found that this is pretty similar to Neurotransmitter too. I guess ...
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316 views

What exactly is the neural receptive field?

Neural receptive fields map the spatial or temporal distribution of the data to individual neuron excitation, if I understand correctly, but I do not understand if receptive fields (especially in the ...
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2k views

SPINAL CORD: Do the axons from white matter synapse with the cell bodies in grey matter?

After wading through a sea of information, I understand the main differences between the white matter and grey matter of the spinal cord. I know that white matter contains myelinated axons in the ...
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65 views

How does a microelectrode work?

On Wikipedia, the entire microelectrode page states only the following: A microelectrode is an electrode of very small size, used in electrophysiology for either recording of neural signals or ...
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60 views

Hydrophobia Outside of Rabies?

RELATED: Why does rabies cause hydrophobia? Agony, Hydrophobia and viruses in the light of evolutionary principles Has hydrophobia been found outside of rabies? I have only seen it ...
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277 views

Do skull bones have pain nerves (nociceptors)?

I recently attended an awake brain surgery for deep brain stimulation and it seemed to me that only the skin surrounding the drilled hole got local anaesthesia. I know that the brain itself does not ...
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124 views

What are the physiological roles of Hydrogen sulfide?

I am thinking why hydrogen sulfide has its effects in the body. For instance, it is one Salmonella's virulence factor. I am not sure if such a balance equations holds H2O + H2S ←→ ... Actually, I ...
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243 views

Benefits of CLARITY?

What are the benefits of CLARITY over this technique that was published more than a year earlier? Of course the second technique needs a fancier microscope that is likely more expensive and requires ...
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89 views

Can 'hardware' thermalization explain memory decay?

Often we are able to memorize very precise bits of information (exact addresses, birthdays of inlaws, number of dirty socks under the bed), but over time our recollection tends to become fuzzy. We no ...
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344 views

Is there a maximum pain threshold?

Is there a maximum threshold of pain a Human can experience, beyond which point there is no noticeable difference? I ask this question in part to better understand the definition of pain and its ...
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244 views

What happens in the synapse when cocaine administration occurs in the human brain

As far as i know when you accept cocaine in your blood some cocaine molecules reach some synapses in your brain and fill some Reuptake tunnels preventing the cell to simply "do not know that fired ...
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207 views

Neuroscience of temperature regulation and perception

The hypothalamus is known to be important in the regulation of body temperature, but I'm curious whether anyone knows about the neurocircuitry of perceived temperature. It seems like there could be a ...
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99 views

What triggers creative thought in humans?

Creativity, innovation and ideation. Is there something in the brain that makes the brain think that way, as opposed to "normal baseline". What triggers creative thought in humans?
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50 views

Hodgin-Huxley model for a single neuron

I am viewing (through edX ) an introduction course to computational neuroscience. In the second lecture, the Hodgin-Huxley model is considered. I am going over some of the questions and have ...
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45 views

Why do negative ions flow into a cell in an inhibitory synapse, even though a neuron has a negative resting potential?

In my spare time I have been reading an introductory Psychology textbook and this question came to my mind after reading about action potentials. I have no previous knowledge in chemistry so if I do ...
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82 views

Oscillatory electrical system using a chain of neurons

Many daily activities that we perform are result of inbuilt oscillatory circuits in our body. For example walking, breathing, heart beat, blinking, etc. The coding and decoding of stored memory also ...
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39 views

Safe parameters for external nerve stimulation using electrical impulses

Introduction I've recently stumbled upon David Eagleman's TED talk on the concept of sensory substitution and addition. Being the most inspiring thing I've seen on the internet for the last few ...
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33 views

What is an auditory upward sweep?

I was reading an article in nature communications, when I came across this sentence: "The ‘match’ rule was indicated by either a blue circle or a auditory upward sweep".So I tried googling what was an ...
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101 views

Is the Hypothalamus part of the Central Nervous System or Endocrine System

Sorry for a certainly naive question. Some references (for example https://faculty.washington.edu/chudler/nsdivide.html) seem to to indicate that the hypothalamus is part of the Central Nervous ...
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59 views

How can I determine the purity of cells isolated from rat brains if I cannot use FACS, Immunohistochemistry or SEM anaysis?

Please help. I know how to isolate the different cells (astrocytes, other glial cells, neurons and synaptosomes) from brain tissue using a Ficoll-based separation but how do I determine the purity of ...
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2answers
57 views

Is there any research on how accurately people can follow a beat?

I'm currently helping develop a rhythm game, and as part of the scoring system, I'd like to make scores and ranks based more on accurate pattern recognition rather than hitting notes very exactly on ...
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60 views

What is meant by drug tolerance?

What is meant by drug tolerance? This question is in my biology textbook for IGCSE and I have no idea what drug tolerance is. It would be very helpful if someone could clarify. Thank you.
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56 views

spinal cord lesion and result in somatic sensation

Jimbo suffers a lesion to the entire right half of the spinal cord at the T6 level. A few weeks after his injury, his doctor tests his right and left legs for somatic sensation and tone. fill out her ...
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280 views

Will neurons live after the death of a human? If so, how long?

I don't know if this is correct or not, but I have heard this from a friend and I want to get a clear explanation about this.I hope there is some one who can help me.
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244 views

Ventral stream pathway and architecture proposed by Poggio's group

Please can you give me a very brief explanation about all functions in the ventral stream architecture summarized in this figure: This figure is from Serre et al.'s A quantitative theory of ...
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55 views

Number of MHCs in neurons

I have read that neurons have proportionately less MHC molecules than other cells of the body. What is the advantage of this?