The study of the structure and function of the nervous system and its components.

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What part of the brain controls depth perception?

Specifically the part of the brain that does depth perception based on binocular vision. I have searched all over the web and have turned up nothing. Is it the same part of the brain that processes ...
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368 views

Does frequency of eye blinking reveal anything about human biology/nervous system?

I'm looking at an output of a single dry sensor EEG headband with the sensor positioned above left eye. As a side effect of it's placement, the device picks up eye blinks, and some eye motion as ...
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52 views

How does Serotonergic (5-HT2A mediated) Psychedelia work?

How does serotonergic (5-HT2A specific) psychedelia work? I've read that there are some theories that it might involve the induction of a glutamate release in certain regions of the brain involved in ...
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327 views

Effects of exercise on the brain

I am well aware of the phenomenon of neurogenesis induced by exercise, as well as the dopamine release that results from exercise. I am really interested in neuropsychology and the effects of exercise ...
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106 views

What light intensity determines the start/end of a photoperiod in humans?

I'm reading this article, which discusses the influence of Long Photoperiod (LP) and Short Photoperiod (SP) on melatonin production: HIOMT drives the photoperiodic changes in the amplitude of the ...
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769 views

Is there a relationship between Melatonin, Norepinephrine and depression in humans?

I'm reading a booklet on melatonin published in 1996, titled "Melatonin and the Biological Clock". This particular paragraph caught my attention and I would like to better understand what it means: ...
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39 views

Case Study and speculations of Edward Mordake

I am very interested in the case of the man named Edward Mordake who lived in the 19th century. In particular, he had two faces. If you have not heard of this man, please, search this up as there are ...
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81 views

Is the six-layer cortex model of the mammalian cortex still the most accepted model?

I've been reading a bit about the different layers of the cerebral cortex and its clear that certainly not every region of the cortex has the same number of layers. Thus, the idea that every region ...
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48 views

What were the first neural systems like?

I'm curious about the origin of the neural network. I'm thinking perhaps once life evolved beyond the single cell organism, it needed a simple neural network to coordinate those cells, and cell ...
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117 views

If D1 receptors stimulate adenylate cyclase (through GPCRs) and D2 receptors inhibit it, then why do mutations in both have similar effects?

D1 and D2 both refer to specific types of dopamine receptors. I'm sure it has something to do with the fact that the D1 receptors are in regions different from D2 receptors. I know that adenylate ...
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65 views

Why does a lack of sleep degrade my balance?

For years, I've noticed that the day after a night of poor sleep (4 hours or less), my balance noticeably degrades. For instance, while walking 20 feet to the coffee maker, I might stumble into the ...
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767 views

Why do neurones use chemical signalling at synaptic junctions?

Problem. When a neurone fires, it sends an electrical signal that jumps down the axon via the nodes of Ranvier very rapidly. At a synaptic junction, chemical brownian diffusion signalling with ...
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162 views

Could an action potential produce few or more neurotransmitters based on the stimulus received?

I reckon that if you would be able to widen the AP width, it would produce more neurotransmitters in that larger time interval. Is that correct? Or does the neuron have a standard amount of ...
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293 views

Where do butterflies sleep?

Do butterflies (insects) sleep, and if so, where?? I have googled for information but didn't get an exact answer.
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166 views

Membrane potential after exposure to glutamate

Neurons were kept in a physiological solution. During the resting phase, the membrane potential in the axoplasm of neurons was negative compared to the extracellular space and a potential ...
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143 views

What are the factors that control the speed of propagation of neuronal signals?

If we consider an analogy between a wire and a neuron there may be some resemblance between the factors controlling the data flow rate. For example the increased width of wire leads to decreased ...
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564 views

Action potential and sodium channels

In this video on electro tonic potential, the tutor says that when the potassium channels open the potential drops from +40mV to -80mV, where the sodium channels have already closed at +40mV. Now in ...
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159 views

How is information sent from limbs to the brain exactly?

Say you have a needle, and you poke a very specific area on your left thumb. A signal gets sent from that nerve up your spine and into your brain. How does the brain know exactly where this signal ...
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79 views

Biological advantage of electric synapses

Electric synapses are synapses that do not process information but simply foward one action potential from one neuron to the next. There are no neurotransmitters, no inhibitory and exitatory ...
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2k views

Neuromediator, Neuromodulator, Neurotransmitter?

Of these three words, perhaps Neurotransmitter is the most obvious. I took a look at Wikipedia page for Neuromodulation and found that this is pretty similar to Neurotransmitter too. I guess ...
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311 views

What exactly is the neural receptive field?

Neural receptive fields map the spatial or temporal distribution of the data to individual neuron excitation, if I understand correctly, but I do not understand if receptive fields (especially in the ...
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2k views

SPINAL CORD: Do the axons from white matter synapse with the cell bodies in grey matter?

After wading through a sea of information, I understand the main differences between the white matter and grey matter of the spinal cord. I know that white matter contains myelinated axons in the ...
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57 views

How does a microelectrode work?

On Wikipedia, the entire microelectrode page states only the following: A microelectrode is an electrode of very small size, used in electrophysiology for either recording of neural signals or ...
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56 views

Hydrophobia Outside of Rabies?

RELATED: Why does rabies cause hydrophobia? Agony, Hydrophobia and viruses in the light of evolutionary principles Has hydrophobia been found outside of rabies? I have only seen it ...
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248 views

Do skull bones have pain nerves (nociceptors)?

I recently attended an awake brain surgery for deep brain stimulation and it seemed to me that only the skin surrounding the drilled hole got local anaesthesia. I know that the brain itself does not ...
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123 views

What are the physiological roles of Hydrogen sulfide?

I am thinking why hydrogen sulfide has its effects in the body. For instance, it is one Salmonella's virulence factor. I am not sure if such a balance equations holds H2O + H2S ←→ ... Actually, I ...
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237 views

Benefits of CLARITY?

What are the benefits of CLARITY over this technique that was published more than a year earlier? Of course the second technique needs a fancier microscope that is likely more expensive and requires ...
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89 views

Can 'hardware' thermalization explain memory decay?

Often we are able to memorize very precise bits of information (exact addresses, birthdays of inlaws, number of dirty socks under the bed), but over time our recollection tends to become fuzzy. We no ...
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328 views

Is there a maximum pain threshold?

Is there a maximum threshold of pain a Human can experience, beyond which point there is no noticeable difference? I ask this question in part to better understand the definition of pain and its ...
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239 views

What happens in the synapse when cocaine administration occurs in the human brain

As far as i know when you accept cocaine in your blood some cocaine molecules reach some synapses in your brain and fill some Reuptake tunnels preventing the cell to simply "do not know that fired ...
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205 views

Neuroscience of temperature regulation and perception

The hypothalamus is known to be important in the regulation of body temperature, but I'm curious whether anyone knows about the neurocircuitry of perceived temperature. It seems like there could be a ...
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99 views

What triggers creative thought in humans?

Creativity, innovation and ideation. Is there something in the brain that makes the brain think that way, as opposed to "normal baseline". What triggers creative thought in humans?
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81 views

Oscillatory electrical system using a chain of neurons

Many daily activities that we perform are result of inbuilt oscillatory circuits in our body. For example walking, breathing, heart beat, blinking, etc. The coding and decoding of stored memory also ...
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32 views

Safe parameters for external nerve stimulation using electrical impulses

Introduction I've recently stumbled upon David Eagleman's TED talk on the concept of sensory substitution and addition. Being the most inspiring thing I've seen on the internet for the last few ...
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31 views

What is an auditory upward sweep?

I was reading an article in nature communications, when I came across this sentence: "The ‘match’ rule was indicated by either a blue circle or a auditory upward sweep".So I tried googling what was an ...
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92 views

Is the Hypothalamus part of the Central Nervous System or Endocrine System

Sorry for a certainly naive question. Some references (for example https://faculty.washington.edu/chudler/nsdivide.html) seem to to indicate that the hypothalamus is part of the Central Nervous ...
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57 views

How can I determine the purity of cells isolated from rat brains if I cannot use FACS, Immunohistochemistry or SEM anaysis?

Please help. I know how to isolate the different cells (astrocytes, other glial cells, neurons and synaptosomes) from brain tissue using a Ficoll-based separation but how do I determine the purity of ...
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57 views

Is there any research on how accurately people can follow a beat?

I'm currently helping develop a rhythm game, and as part of the scoring system, I'd like to make scores and ranks based more on accurate pattern recognition rather than hitting notes very exactly on ...
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59 views

What is meant by drug tolerance?

What is meant by drug tolerance? This question is in my biology textbook for IGCSE and I have no idea what drug tolerance is. It would be very helpful if someone could clarify. Thank you.
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spinal cord lesion and result in somatic sensation

Jimbo suffers a lesion to the entire right half of the spinal cord at the T6 level. A few weeks after his injury, his doctor tests his right and left legs for somatic sensation and tone. fill out her ...
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263 views

Will neurons live after the death of a human? If so, how long?

I don't know if this is correct or not, but I have heard this from a friend and I want to get a clear explanation about this.I hope there is some one who can help me.
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241 views

Ventral stream pathway and architecture proposed by Poggio's group

Please can you give me a very brief explanation about all functions in the ventral stream architecture summarized in this figure: This figure is from Serre et al.'s A quantitative theory of ...
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55 views

Number of MHCs in neurons

I have read that neurons have proportionately less MHC molecules than other cells of the body. What is the advantage of this?
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739 views

Optogenetics - How do microbial opsins work?

I'm just introduced to the optogenetics method and am having some trouble grasping the genetics (of the optogenteics) part of things. So we have Retinal and Opsin that form Rhodopsin molecule that ...
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Is “tonic activity” common for neurons firing in the brain?

I've been reading about Dorsal Raphe Nucleus, a serotonin- rich part of the brain. I noticed mentioning of "tonic activity" - regular pulsing that releases neurotransmitters. On top of this "tone" the ...
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372 views

How is propagation of action potentials terminated once the “message” has been sent/received?

I'm thinking about neurons in the brain that are used for "thinking". As I read about action potentials, I see that an Axon is connected to a Dendrite of a neighboring cell and that there are ...
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78 views

Text/resource with information on all skeletal muscles and their motor units

Something analogous to an encyclopedia on baseball players with a list of all thier stats would be ideal. I'm not looking for just generic muscle names, locations and illustrations. Good answers ...
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2answers
284 views

Does body mass have a bearing on reflex speed?

A reflex is an unconscious action in response to some specific stimulus, e.g., blinking an eye, or pulling the hand away from a hot pin I know from school biology, and reading online that withdrawal ...
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42 views

Can a postsynaptic neuron 'shut itself off?

I am an amateur interested in neuroscience and was curious whether there is a process by which a neuron or group of neurons would close their receptors and stop receiving signals from specific ...
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144 views

dopamine paradox in Schizophrenia

If there is more dopamine action in the mesocortical pathway in Schizophrenia, then the patients should always be in euphoric state. But instead patient lacks motivation and don't want pleasure. Why?