The study of the structure and function of the nervous system and its components.

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Criteria for compound action potential thresholds

As opposed to action potential thresholds (which are binary yes/no events), electrophysiological thresholds of compound action potentials are arbitrary. Mostly a certain noise level is picked and when ...
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60 views

Do local field potentials (LFP) create waves on the surfaces of nerve cells?

Are waves created by the LFP on the surfaces of neurons cell bodies? Since the cells have a resting potential, do these waves create harmonic oscillation of the membranes at particular frequencies? ...
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93 views

The mechanism of mechanoreception?

I am interested in knowing the molecular mechanism behind mechanoreception/mechanotransduction (i.e. mechanism behind receptor potential generation on mechanical stimulation). I know that most ...
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298 views

Are there any types of cancer that cause neurons to divide?

After birth neurons generally do not divide. But is there any specific type of rare cancer or tumour where neurons divide? And if there is such a cancer, then how is it possible for a neuron to regain ...
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47 views

What are the molecular mechanisms that make the turtle brain more resistant to hypoxia?

I know that turtle brains, particularly those of individual species that hibernate and burrow are particularly resilient to hypoxia and any tissue damage secondary to a hypoxic event. What are the ...
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48 views

Is there a type of amnesia that seperately affects long-term memory?

Is there a medical condition that affects the long term memory, but leaving the short-term and working memories totally or fairly intact?
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983 views

Why Do Nerve Signals Get Crossed?

First off, I don't know if this is a normal healthy thing to occur. There have been many times where I have an itch on say my arm and I scratch it, only to feel the scratching elsewhere on my body. I ...
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228 views

Is it technically possible to make someone see something when their eyes are closed?

I'm writing a little article and need any information about how human vision works and latest technologies and discoveries around. Actually its not a professional article. Its for a group of my ...
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522 views

How does the eugeroic modafinil work?

How does the drug, modafinil (Provigil), exert its eugeroic (wakefulness-promoting) effects? I've read that it works by increasing dopamine and histamine concentrations in the CNS and by serving as a ...
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170 views

What is the purpose of the adrenal medulla?

The adrenal medulla is less of a 'real' endocrine organ like the others in the endocrine system and much more an extension of the sympathetic nervous system. In fact, its chromaffin cells are modified ...
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338 views

How does the brain know where a signal came from? What is the addressing system

I am an electronic engineer so I am thinking about this from an electronics outlook. How does the addressing system work, As I see it, the nervous system is small parallel branches attached to larger ...
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189 views

Does playing music during sleep actually suppress rather than rouse the brain?

I've long been interested in the effect of music/sound on dreaming, and even built 2 apps that play music during REM period. Now I'm looking at this article about FMRI studies of a sleeping brain, and ...
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74 views

Missing cells from immunopanning

Why do I not have any cells left in my positive panning plate after transferring from the negative panning plate during immunopanning? I am trying to purify retinal ganglion cells from postnatal rats ...
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2k views

What part of the brain controls depth perception?

Specifically the part of the brain that does depth perception based on binocular vision. I have searched all over the web and have turned up nothing. Is it the same part of the brain that processes ...
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401 views

Does frequency of eye blinking reveal anything about human biology/nervous system?

I'm looking at an output of a single dry sensor EEG headband with the sensor positioned above left eye. As a side effect of it's placement, the device picks up eye blinks, and some eye motion as ...
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52 views

How does Serotonergic (5-HT2A mediated) Psychedelia work?

How does serotonergic (5-HT2A specific) psychedelia work? I've read that there are some theories that it might involve the induction of a glutamate release in certain regions of the brain involved in ...
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332 views

Effects of exercise on the brain

I am well aware of the phenomenon of neurogenesis induced by exercise, as well as the dopamine release that results from exercise. I am really interested in neuropsychology and the effects of exercise ...
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111 views

What light intensity determines the start/end of a photoperiod in humans?

I'm reading this article, which discusses the influence of Long Photoperiod (LP) and Short Photoperiod (SP) on melatonin production: HIOMT drives the photoperiodic changes in the amplitude of the ...
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834 views

Is there a relationship between Melatonin, Norepinephrine and depression in humans?

I'm reading a booklet on melatonin published in 1996, titled "Melatonin and the Biological Clock". This particular paragraph caught my attention and I would like to better understand what it means: ...
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70 views

Can axons act as receptors?

In all histology books, it is stated that all sensory nerve endings (receptors) consist of dendrites that translate physical stimuli from the environment into neural signals. However, several sensory ...
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If D1 receptors stimulate adenylate cyclase (through GPCRs) and D2 receptors inhibit it, then why do mutations in both have similar effects?

D1 and D2 both refer to specific types of dopamine receptors. I'm sure it has something to do with the fact that the D1 receptors are in regions different from D2 receptors. I know that adenylate ...
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68 views

Why does a lack of sleep degrade my balance?

For years, I've noticed that the day after a night of poor sleep (4 hours or less), my balance noticeably degrades. For instance, while walking 20 feet to the coffee maker, I might stumble into the ...
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809 views

Why do neurones use chemical signalling at synaptic junctions?

Problem. When a neurone fires, it sends an electrical signal that jumps down the axon via the nodes of Ranvier very rapidly. At a synaptic junction, chemical brownian diffusion signalling with ...
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168 views

Could an action potential produce few or more neurotransmitters based on the stimulus received?

I reckon that if you would be able to widen the AP width, it would produce more neurotransmitters in that larger time interval. Is that correct? Or does the neuron have a standard amount of ...
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298 views

Where do butterflies sleep?

Do butterflies (insects) sleep, and if so, where?? I have googled for information but didn't get an exact answer.
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Membrane potential after exposure to glutamate

Neurons were kept in a physiological solution. During the resting phase, the membrane potential in the axoplasm of neurons was negative compared to the extracellular space and a potential ...
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607 views

Action potential and sodium channels

In this video on electro tonic potential, the tutor says that when the potassium channels open the potential drops from +40mV to -80mV, where the sodium channels have already closed at +40mV. Now in ...
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Can dietary monosodium glutamate intake induce restlestness?

The question is all in the title. More context: I like phở soup. I have noticed that I get restless after eating the phở soup at some restaurants. The effects are similar to the ones resulting from ...
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What are the factors that control the speed of propagation of neuronal signals?

If we consider an analogy between a wire and a neuron there may be some resemblance between the factors controlling the data flow rate. For example the increased width of wire leads to decreased ...
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163 views

How is information sent from limbs to the brain exactly?

Say you have a needle, and you poke a very specific area on your left thumb. A signal gets sent from that nerve up your spine and into your brain. How does the brain know exactly where this signal ...
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80 views

Biological advantage of electric synapses

Electric synapses are synapses that do not process information but simply foward one action potential from one neuron to the next. There are no neurotransmitters, no inhibitory and exitatory ...
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2k views

Neuromediator, Neuromodulator, Neurotransmitter?

Of these three words, perhaps Neurotransmitter is the most obvious. I took a look at Wikipedia page for Neuromodulation and found that this is pretty similar to Neurotransmitter too. I guess ...
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322 views

What exactly is the neural receptive field?

Neural receptive fields map the spatial or temporal distribution of the data to individual neuron excitation, if I understand correctly, but I do not understand if receptive fields (especially in the ...
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2k views

SPINAL CORD: Do the axons from white matter synapse with the cell bodies in grey matter?

After wading through a sea of information, I understand the main differences between the white matter and grey matter of the spinal cord. I know that white matter contains myelinated axons in the ...
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82 views

How does a microelectrode work?

On Wikipedia, the entire microelectrode page states only the following: A microelectrode is an electrode of very small size, used in electrophysiology for either recording of neural signals or ...
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Hydrophobia Outside of Rabies?

RELATED: Why does rabies cause hydrophobia? Agony, Hydrophobia and viruses in the light of evolutionary principles Has hydrophobia been found outside of rabies? I have only seen it ...
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307 views

Do skull bones have pain nerves (nociceptors)?

I recently attended an awake brain surgery for deep brain stimulation and it seemed to me that only the skin surrounding the drilled hole got local anaesthesia. I know that the brain itself does not ...
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131 views

What are the physiological roles of Hydrogen sulfide?

I am thinking why hydrogen sulfide has its effects in the body. For instance, it is one Salmonella's virulence factor. I am not sure if such a balance equations holds H2O + H2S ←→ ... Actually, I ...
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246 views

Benefits of CLARITY?

What are the benefits of CLARITY over this technique that was published more than a year earlier? Of course the second technique needs a fancier microscope that is likely more expensive and requires ...
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Can 'hardware' thermalization explain memory decay?

Often we are able to memorize very precise bits of information (exact addresses, birthdays of inlaws, number of dirty socks under the bed), but over time our recollection tends to become fuzzy. We no ...
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362 views

Is there a maximum pain threshold?

Is there a maximum threshold of pain a Human can experience, beyond which point there is no noticeable difference? I ask this question in part to better understand the definition of pain and its ...
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253 views

What happens in the synapse when cocaine administration occurs in the human brain

As far as i know when you accept cocaine in your blood some cocaine molecules reach some synapses in your brain and fill some Reuptake tunnels preventing the cell to simply "do not know that fired ...
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217 views

Neuroscience of temperature regulation and perception

The hypothalamus is known to be important in the regulation of body temperature, but I'm curious whether anyone knows about the neurocircuitry of perceived temperature. It seems like there could be a ...
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100 views

What triggers creative thought in humans?

Creativity, innovation and ideation. Is there something in the brain that makes the brain think that way, as opposed to "normal baseline". What triggers creative thought in humans?
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203 views

Have webs woven by LSD-intoxicated spiders ever been studied for their efficiency in fly catching?

I ask, because I have a different interpretation of the experiments performed on web-weaving spiders. The famous Robert Pirsig maintains that LSD is somehow helpful to web-weaving spiders, because it ...
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54 views

Hodgin-Huxley model for a single neuron

I am viewing (through edX ) an introduction course to computational neuroscience. In the second lecture, the Hodgin-Huxley model is considered. I am going over some of the questions and have ...
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52 views

Why do negative ions flow into a cell in an inhibitory synapse, even though a neuron has a negative resting potential?

In my spare time I have been reading an introductory Psychology textbook and this question came to my mind after reading about action potentials. I have no previous knowledge in chemistry so if I do ...
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56 views

Neuroscience behind the crash

After experiencing things like stress, intense exercise, or using drugs such as caffeine and amphetamine, subjects often assume a depressive and lethargic state afterwards, known as a "crash." What is ...
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82 views

Oscillatory electrical system using a chain of neurons

Many daily activities that we perform are result of inbuilt oscillatory circuits in our body. For example walking, breathing, heart beat, blinking, etc. The coding and decoding of stored memory also ...
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Safe parameters for external nerve stimulation using electrical impulses

Introduction I've recently stumbled upon David Eagleman's TED talk on the concept of sensory substitution and addition. Being the most inspiring thing I've seen on the internet for the last few ...