The study of the structure and function of the nervous system and its components.

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Mechanical cause of loss of consciousness

Consciousness is an electrical and chemical interaction in the brain, caused by neurons firing and chemical interactions. How does a mechanical "force" cause this to stop working? i.e. How does a ...
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692 views

What is 'calcium conductance'?

What is the meaning of calcium conductance in ion channels. I encountered this in the following text: It was established that the µ and δ opioid receptors open potassium channels, which results ...
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148 views

Why are things conscious?

I've been referred to here from http://philosophy.stackexchange.com/questions/8052/why-are-things-conscious. Could you guys help out? Here's the question: What is the reason for animals or more ...
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36 views

What Role Antagonists Play in the Study of Drugs?

I am pretty unfamiliar to pharmacology. I'm doing a research on drug abuse, particularly opioids' mechanism of action. I encountered several times evidences that come from studies using antagonists ...
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1answer
69 views

Missing cells from immunopanning

Why do I not have any cells left in my positive panning plate after transferring from the negative panning plate during immunopanning? I am trying to purify retinal ganglion cells from postnatal rats ...
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66 views

Does pain scale with mammal mass?

Some biological features scale with the animal mass (see previous Q&A). Assuming the same concentration of nociceptors on the skin surface, I'm wondering how painful a 1 cm wound will be ...
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85 views

Do voltage-gated calcium channels affect neuronal conduction speeds?

We have a hypothesis that a drug may block the voltage-gated calcium channels (VGCC) in annelid worms. We are wondering whether there are any correlations between VGCCs and neuron conduction ...
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321 views

If a dead snake reflexively attacks itself, why does it not always attack itself?

Recently there has been this video going around of a snake that had been decapitated. Its body swung around to the decapitated head and the head attacked the body on "reflex". Now we know that most ...
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2k views

Neuromediator, Neuromodulator, Neurotransmitter?

Of these three words, perhaps Neurotransmitter is the most obvious. I took a look at Wikipedia page for Neuromodulation and found that this is pretty similar to Neurotransmitter too. I guess ...
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68 views

What decides the position of the node of Ranvier?

The oligodendrocytes makes the myelin sheath in CNS and schwann cells make it in PNS. What decides where the oligodendrocyte or Schwann cell will attach and start forming myelin sheath? Is it ...
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1answer
150 views

What areas of the brain are involved in doing arithmetic operations?

Do neuroscientists already know what areas of the brain are involved in mental calculations? Has any fruitful research been done on that or not yet? Do you think that if we understand what areas of ...
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171 views

If people with colorblindness lack one type of cone cells, shouldn't they be unable to recognize one particular color?

The 3 types of cone cells in normal humans allow them to view 3 types of colors and any color made from mixing and matching those 3. So, 2 types of cone cells should only allow to view just 2 types ...
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115 views

Do people with colorblindness have less cones or no cones of a certain type?

https://en.wikipedia.org/wiki/Color_blindness#Red.E2.80.93green_color_blindness Protanopia (1% of males): Lacking the long-wavelength sensitive retinal cones, Deuteranopia (1% of males): ...
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1answer
142 views

Molecules and human memory

Has it been demonstrated that the memory of human brain is just connections between neurons, not "long" molecules such as RNA or proteins?
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1k views

What is a cortical circuit?

I have read about cortical circuits in the context of connectomics (e.g. any example here) and computational neuroscience (e.g. any example here), but a simple Google/Wikipedia does search not show an ...
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1answer
175 views

Is Nerve Growth Factor (NGF) commercially available?

I'm curious if NGF, or Neurotrophins in general is available commercially. Can I order it online? If not, what are the medical/biological reasons. Does it breakdown quickly after synthesis/capture? Is ...
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1answer
139 views

Is (Brain Mass)/(Total Mass) still considered a valid indicator of intelligence?

I was reading this(1) and it led me back to ask a very basic question (I'm not a neuroscientist). All the way back to undergrad anthropology and neuroscience courses I remember being taught the ...
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311 views

What exactly is the neural receptive field?

Neural receptive fields map the spatial or temporal distribution of the data to individual neuron excitation, if I understand correctly, but I do not understand if receptive fields (especially in the ...
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1answer
207 views

Are these claims of “revolutionising” understanding of human vision and hearing valid?

I've started a hobby machine vision project (and posted some questions to this end on other SE sites) and on a side track, also been looking at relevant research in human vision (and partly, hearing). ...
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87 views

Are there “multi-frequency” signals within a human brain?

I know that neurons can exhibit tonic and phasic firing, and also that a neuron is sometimes called an integrator. This makes me interested to know if there are activities in the brain that depend on ...
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1answer
151 views

What is the limit of time resolution in fMRI?

I was reading about a few studies on estimating functional connectivity between brain areas using fMRI signals. However, as far as I know that fMRI has a very poor time resolution, roughly in the ...
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1answer
175 views

Hearing and neurons- do ears have a sampling period?

From what I have read, outer hair cells in the human ear amplify incoming signals and inner hair cells "pick-up" the signals and generate action potential. However, neurons have refractory periods ...
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1answer
381 views

How different is an introverts brain different from an extroverts?

How is an introverts brain wired differently than an extroverts? Just to give you an example. On an average, the processing that goes on in an introverts brain is greater than in an extroverts ...
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1answer
12k views

What are the functions and differences between axons and dendrites?

My textbook doesn't do a very good job of pointing out what the differences between the two are. It basically mentions axons only in the same breath as the synapse (that synapses are the endings/tips ...
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393 views

Can parts of a human brain be asleep independently of each other, or vary in the times required for them to fall asleep?

I know that some birds and marine animals can continue complicated activity (swimming, flying?) while one hemisphere of their brain is asleep. I'm interested if human brain has some parts of it that ...
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1answer
48 views

Is there a type of amnesia that seperately affects long-term memory?

Is there a medical condition that affects the long term memory, but leaving the short-term and working memories totally or fairly intact?
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1answer
80 views

Eye Brain Mapping

If our eyes are separated by some kind of full proof barrier/isolation, is it possible that our brain can picture/visualize two different pictures at a time? How the brain will function in this ...
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1answer
2k views

What part of the brain controls depth perception?

Specifically the part of the brain that does depth perception based on binocular vision. I have searched all over the web and have turned up nothing. Is it the same part of the brain that processes ...
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2k views

Why do neurons have a negative resting potential?

Neurons expend the majority of their energy powering ion pumps to maintain the chemical gradients that power their electrical activity. To have a negative resting potential, neurons leak potassium ...
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1answer
142 views

Do nerve cells cause action potential in cardiac muscle?

I think the answer is no, but I am not 100% sure. If it was yes, then the dendrite of the nerve cell should each time receive a stimulus causing Na+ channels to open, when the contraction happen. ...
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1answer
742 views

Optogenetics - How do microbial opsins work?

I'm just introduced to the optogenetics method and am having some trouble grasping the genetics (of the optogenteics) part of things. So we have Retinal and Opsin that form Rhodopsin molecule that ...
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3answers
178 views

What is the difference between different brain regions

The brain is separated into different regions, and different regions perform different tasks. Well, what are the differences between these regions on the cellular/systemic level. The brain is made up ...
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2answers
127 views

Inverse of dopamine reuptake inhibitor?

The wikipedia article on the dopamine transporter gives examples of some drugs whose effects are mediated by the inhibition of the dopamine transporter, such as cocaine and amphetamines. Are there ...
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2answers
1k views

What is in the space between neurons in a brain?

When neuron animations are displayed, there are frequently seen neurons, axons arranged in a lattice with a lot of empty space between. I'm interested if there is indeed empty space in the brain, or ...
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283 views

Does brain activity generate heat gradients in the brain?

I'm reading this article on guiding axon growth using temperature gradient, and it mentions that the trajectory of growth of neuron connections can be influenced by temperature gradients as little as ...
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1answer
842 views

Cat purring: What are some possible underlying mechanisms behind purring and bone remodeling and formation?

http://www.scientificamerican.com/article.cfm?id=why-do-cats-purr The article above says that cats purr mostly when they're wounded or under duress. They hypothesis that cats purring leads to ...
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3answers
769 views

Why do neurones use chemical signalling at synaptic junctions?

Problem. When a neurone fires, it sends an electrical signal that jumps down the axon via the nodes of Ranvier very rapidly. At a synaptic junction, chemical brownian diffusion signalling with ...
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1answer
712 views

Why does it hurt more when you touch a nerve directly?

I am not a biologist nor know much about biology (so please explain in layman's terms) however I have always been curious as to why this is. What causes the difference in pain between touching an ...
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1answer
59 views

Are there neuronal firing artifacts produced by head movement?

I'm experimenting with a consumer-grade ElectroEncephaloGram (EEG) sensor and have created the image below using the device. Because the sensor on the device does not use a suction cup, there are a ...
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226 views

How does a pinched nerve cause pain (at the molecular level)?

Is this due to pressure differentials in the surrounding tissue? (Is it possible to have a pinched nerve without compression of the surrounding tissues, and does this cause pain?) What are the ...
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2answers
4k views

Why is saltatory conduction faster than continuous conduction?

How does spacing apart sodium and potassium channels allow the action potential to travel faster down the axon? This is the reason always cited for saltatory conduction and myelination, but my mental ...
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1answer
74 views

What processes are responsible for focusing on an image only seen by one of the eyes?

When a person is spying from around a corner with only one eye, it's rather easy to ignore the other eye's image, since it's probably much darker, because one usually spies around a corner standing ...
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1answer
223 views

Why do I see an inverted image of an object when I close my eyes?

If I stare at an object for a long time and close my eyes, at first I can still see the object with my eyes closed. But the image I see with my eyes closed is inverted: dark colors appear as light and ...
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2answers
3k views

What is the function of nodes of Ranvier in axons?

In a neuroscience class I'm taking, it was explained that myelin covers axons in sections, the uncovered sections are called nodes of Ranvier, and signals propagate much faster in the covered ...
2
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1answer
76 views

Carrying or packaging capacity of SAD B19 dG rabies virus

I'm wondering about the carrying capacity also referred to packaging capacity or loading capacity (how many base pairs can be packed efficiently into virions) of the pseudotyped rabies virus SAD-dG as ...
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0answers
123 views

How long does Lentivirus take to express in vivo mouse neurons?

Does anyone know how long it takes for a standard Lentivirus vector to express its genes (under a strong promoter such as CAG, CB7, etc.), after injection into the brain of a mouse? By hearsay I ...
2
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1answer
422 views

How exactly does marijuana damage brain cells?

I've heard that THC can cause permanent damage to brain cells. I've also heard this reffered to anti drug propaganda. Another theory i've read is that temporary effects reduce intelligence but long ...
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1answer
159 views

How do axon terminals report to the soma?

It is important to bear in mind that the distance between a neuron's axon terminal and its soma can be extensive, up to about 1m in the human body. The fastest transport along the axon is 400mm/day ...
4
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1answer
903 views

Why Do Nerve Signals Get Crossed?

First off, I don't know if this is a normal healthy thing to occur. There have been many times where I have an itch on say my arm and I scratch it, only to feel the scratching elsewhere on my body. I ...
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Is it technically possible to make someone see something when their eyes are closed?

I'm writing a little article and need any information about how human vision works and latest technologies and discoveries around. Actually its not a professional article. Its for a group of my ...