The study of the structure and function of the nervous system and its components.

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Ventral stream pathway and architecture proposed by Poggio's group

Please can you give me a very brief explanation about all functions in the ventral stream architecture summarized in this figure: This figure is from Serre et al.'s A quantitative theory of ...
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55 views

Number of MHCs in neurons

I have read that neurons have proportionately less MHC molecules than other cells of the body. What is the advantage of this?
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768 views

Optogenetics - How do microbial opsins work?

I'm just introduced to the optogenetics method and am having some trouble grasping the genetics (of the optogenteics) part of things. So we have Retinal and Opsin that form Rhodopsin molecule that ...
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2k views

Is “tonic activity” common for neurons firing in the brain?

I've been reading about Dorsal Raphe Nucleus, a serotonin- rich part of the brain. I noticed mentioning of "tonic activity" - regular pulsing that releases neurotransmitters. On top of this "tone" the ...
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375 views

How is propagation of action potentials terminated once the “message” has been sent/received?

I'm thinking about neurons in the brain that are used for "thinking". As I read about action potentials, I see that an Axon is connected to a Dendrite of a neighboring cell and that there are ...
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79 views

Text/resource with information on all skeletal muscles and their motor units

Something analogous to an encyclopedia on baseball players with a list of all thier stats would be ideal. I'm not looking for just generic muscle names, locations and illustrations. Good answers ...
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300 views

Does body mass have a bearing on reflex speed?

A reflex is an unconscious action in response to some specific stimulus, e.g., blinking an eye, or pulling the hand away from a hot pin I know from school biology, and reading online that withdrawal ...
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42 views

Can a postsynaptic neuron 'shut itself off?

I am an amateur interested in neuroscience and was curious whether there is a process by which a neuron or group of neurons would close their receptors and stop receiving signals from specific ...
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145 views

dopamine paradox in Schizophrenia

If there is more dopamine action in the mesocortical pathway in Schizophrenia, then the patients should always be in euphoric state. But instead patient lacks motivation and don't want pleasure. Why?
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398 views

What happens in your brain when you receive information which causes you to bristle?

I'm talking about moments when you watch a film and you bristle, or when you listen to music, etc. What kind of neurotransmitter flow changes?
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86 views

Do voltage-gated calcium channels affect neuronal conduction speeds?

We have a hypothesis that a drug may block the voltage-gated calcium channels (VGCC) in annelid worms. We are wondering whether there are any correlations between VGCCs and neuron conduction ...
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179 views

Hearing and neurons- do ears have a sampling period?

From what I have read, outer hair cells in the human ear amplify incoming signals and inner hair cells "pick-up" the signals and generate action potential. However, neurons have refractory periods ...
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155 views

Which Receptors are Involved in the antidepressant effects of SSRIs?

From what I've read the major receptor subtypes involved in the antidepressant effects of SSRIs are: 5-HT1A 5-HT2C 5-HT3 5-HT6 Please cite journal articles to back up your claims, I don't want any ...
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1k views

Physiological indicators of happiness and well being

If I understand it correctly, levels of serotonin in the brain can indicate if a person is happy. What other physiological measures indicate happiness or well being for a humans? I am looking for ...
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256 views

Does the speed of electrical impulses through neurones decrease with age?

From what I read on the NatGeo app, it stated that the speed of the electrical impulses that are sent by a neurone will be approximately 332 kilometers per hour. Will the speed of this electrical ...
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279 views

Why apes started to contemplate and become altruistic? [closed]

I was asking this first on philosophy forums, but it is suggested, that answer could be found from evolutionary view of point, so here we go: Again my question raised when thinking of myths, their ...
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35 views

Does tremor frequency generally increase as Parkinson's disease progresses?

I've been trying to research this question, but most if not all the on-line journals require costly subscription, and the studies that are posted look at tremor frequency with regards to other ...
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38 views

Neuroscience behind the crash

After experiencing things like stress, intense exercise, or using drugs such as caffeine and amphetamine, subjects often assume a depressive and lethargic state afterwards, known as a "crash." What is ...
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50 views

Neural coupling between Pinsky-Rinzel (reduced Traub) neuron with a Wang-Buzsaki neuron?

I have read two papers related to modeling neurons. The first one is the paper by Pinsky and Rinzel and the second one by Wang and Buzsaki. The first mentioned neuron model is a excitatory neuron ...
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60 views

How we share pain?

When somebody else tells me about his or her itching or pain in some specific body part I sometimes begin to feel similar feelings. I can think of about three explanations: I feel pain all over my ...
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44 views

Cross section of actin network in neurites

for a simulation I am developing I would like to know how the actin network in neurites is distributed. Is actin confined to the periphery or is the whole neurite shaft containing actin with a rather ...
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47 views

The use of proteins in memory creation

I have very limited knowledge of how the human memory works as I think, at this time, most people do. However, I have been reading and some articles which say, and I quote the article just linked ...
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222 views

Saltatory Conduction Of Nerve Impulses

I am aware about some basics of Saltatory conduction of nerve impulses. I know that the nerve impulses(ionic flow and the depolarization) are transferred from the node to the node in myelinated nerve ...
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59 views

Nocioception (pain perception) in subcutaneous tissue

There seem to be no nocioceptors (pain and temperature sensitive nerve endings) in subcutaneous fat. there are nocioceptors and other receptors in veins running through fat, but these can be avoided. ...
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62 views

The Operation of tuning in the S1 layer of ventral model

According to my previous question in ventral Stream pathway and architecture, I want now to get a brief example about how the S1 layer is constructed. In other words, how all the simple units are ...
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3answers
426 views

Can human brain memory be removed by EMP?

The human brain is the most complicated human organ so it is hard to examine it completely but based on what we know do you think (or do you know from some source) if a human memory can be removed by ...
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93 views

What are dreams, biologically?

Falling asleep or states of subconsciousness does not stop the mind from making its own fictional images. These seem like sensations just like those received from human eyes. But, how do we define ...
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133 views

Can connections between neurons be weakened?

Connections between neurons are said (by Wikipedia) to be strengthened as part of learning - can they also be weakened (below the original level)? I understand the concept of the connections ...
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1k views

What is in the space between neurons in a brain?

When neuron animations are displayed, there are frequently seen neurons, axons arranged in a lattice with a lot of empty space between. I'm interested if there is indeed empty space in the brain, or ...
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109 views

Parallels between pixelized image and the human retina

On Wikipedia it is explained that the human eye has a certain 'resolution'. Does this mean that the retinal image consists of pixels? If yes, what shape would these pixels have?
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36 views

What Role Antagonists Play in the Study of Drugs?

I am pretty unfamiliar to pharmacology. I'm doing a research on drug abuse, particularly opioids' mechanism of action. I encountered several times evidences that come from studies using antagonists ...
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658 views

Is there such thing as “half-life” of dopamine?

If a dopamine is released at T=0 and binds to receptor D2, what determines the time when the concentration of this neurotransmitter bound to the receptor reaches half of the original concentration? In ...
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101 views

Book recommended for neurobiology

I am looking for a good explanatory book concerning Neurobiology. I am interested on how the brain works but prior to this I believe that I have to start learning things about the biology of neurons. ...
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266 views

Action potential changes in low sodium concentrations but constant osmotic pressure

If I bathe a squid axon in a fluid that has high sodium concentration , why does the duration of action potential decrease compared to a control experiment in low sodium bath but maintained at the ...
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89 views

How small does a nanobot have to be to “swim through the brain” and access any neuron it wants to?

I read on this question What is in the space between neurons in a brain? that there is actually not much empty space in a brain. But my question is slightly different. Is there a visual demonstration ...
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362 views

Neurons with thousands of connections: where are the extra connections coming from?

If every neuron has only one Axon but can can have thousands of (or let's say, even just ten) incoming Axon connections via its dendrites, where are the extra connections coming from? It seems to ...
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128 views

Thoughts precede neuron firing or vise-verse?

I am at the verge of submitting a paper on 'scientific explanation of reality' to an international philosophy body. First submitted draft was returned by the evaluation expert, asking me to re-submit ...
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218 views

Mechanical cause of loss of consciousness

Consciousness is an electrical and chemical interaction in the brain, caused by neurons firing and chemical interactions. How does a mechanical "force" cause this to stop working? i.e. How does a ...
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432 views

How exactly does marijuana damage brain cells?

I've heard that THC can cause permanent damage to brain cells. I've also heard this reffered to anti drug propaganda. Another theory i've read is that temporary effects reduce intelligence but long ...
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214 views

Why does chewing enrage me?

Whether it's snacking on chips, munching on salad, or simply chewing gum, when I hear someone do it within an earshot, it drives me completely bonkers! It doesn't matter if it's my girlfriend, my ...
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97 views

Resting and action membrane potential..?

In the resting membrane potential of neurons the inside of membrane is kept negative and outside of membrane is kept positive by the utilization of energy through Na-K Atpase pump, While during action ...
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98 views

What will happen if we expose the brain to an intermittent light?

If a brain is exposed to an intermittent light are specific areas going to fire? If yes, which of them? Is there any experiment about this?
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1k views

What is a cortical circuit?

I have read about cortical circuits in the context of connectomics (e.g. any example here) and computational neuroscience (e.g. any example here), but a simple Google/Wikipedia does search not show an ...
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61 views

Is numbness the absence of one or all touch sensations?

I am studying the effects of tetrodotoxin and its symptoms when consumed. Numbness is one of the first sensations reported. But I googled numbness and I couldn't find information about whether this ...
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85 views

What would be required to evolve an animal (non-human) brain to obtain human-level cognition? [closed]

Could any animal subject to the right conditions evolve human-level intelligence? Suppose that an artificial intelligence (AI) decided to artificially evolve a population of octopus (don't ask why, ...
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69 views

Why are skin tactile receptors considered to be phasic receptors?

A phasic receptor by definition is one that quickly adapts to change. In terms of neuron firing, this means that it does not trigger another firing because the receptors are used to the stimulus. But ...
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102 views

Is it possible to process electrical signals from the brain and interpret the results as exact thoughts?

If the brain uses extremely low voltage signals to communicate (from what I understand around 100 mV), what sort of breakthroughs would be necessary to intercept these signals and interpret them as ...
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319 views

What percent of the population has some form of synesthesia?

Data I am trying to get my hands on: What types of synesthesia (e.g. Grapheme-color synesthesia, Chromesthesia, etc.) are most common across the population? What percent of population has that ...
2
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1answer
261 views

What is the difference between clinical and non-clinical depression, and is there a term for different severity of the bipolar disorder?

I was looking for a term which describes a bipolar disorder of lesser severity. I know from experience from someone I know well, what a very severe case of the bipolar disorder looks like, when an ...
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115 views

Why do the neuron pathways decussate?

I learn about the brain right now, and there are crossing of neuron pathways everywhere; in the thalamus, the medulla oblongata, the pyramidal tract... And I don't understand why? What is the reason ...