The study of the structure and function of the nervous system and its components.

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41 views

What can myelination tell you about the evolution of sensory receptors?

I am reading Avi Chaudhuri's Fundamentals of Sensory Perception and wondering if the information given about the somatosensory system could tell us anything about the way it evolved. It seems (at ...
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35 views

Kinesin-5 / cytoplasmic dynein spatial density distribution in neurons

Is there some way to experimentally determine the density distribution of Kinesin and Dynein in a Neuron? Fluorescence labeling would be impossible(?) as GFP markers would probably alter the motor ...
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31 views

Neuroscience: zapping an axon connected to thermoreceptor

Let’s say an experimenter has an electrode that can give a shock to a single axon. She takes that electrode and zaps an axon connected to thermoreceptors in the hand of her subject. I) What would the ...
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38 views

What's the best way to measure/calculate the size of a light beam at the sample of a microscope?

I am using a microscope with an LED derived light through the epi-fluorescent port of a microscope. I know that the "field of view" for a given objective is equal to the field number/magnification ...
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90 views

Solubility of Forskolin in ethanol

I am interested in using forskolin in cell culture medium. Does anyone know how to make solution of 10 microM forskolin in 5% ethanol or less. I would like to avoid using DMSO as a solvent. Thank you. ...
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66 views

What happens during a Raynauds episode?

Raynaud's phenomenon can be a serious health issue, as the blood flow to the extremities, mainly the fingers is compromised, causing fingers to blanche, and then turn blue. Severe Raynaud's can cause ...
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112 views

What is the full name of E. G. Gray?

E. G. Gray is Neuro scientist who found and described first the two major morphologically defined synapse types (Gray Type I (asymmetric) and II (symmetric)) in his work E G Gray (Oct. 1959). ...
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109 views

Do people with colorblindness have less cones or no cones of a certain type?

https://en.wikipedia.org/wiki/Color_blindness#Red.E2.80.93green_color_blindness Protanopia (1% of males): Lacking the long-wavelength sensitive retinal cones, Deuteranopia (1% of males): ...
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127 views

In scuba diving, are nitrogen narcosis and high pressure nervous syndrome the same thing?

In training for scuba diving, they tell you that when you're bellow 100 ft or so you have to watch out for changes in mental state that resemble drunkenness. The cause of these mental disturbances is ...
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127 views

How stable is in vivo whole cell patch clamping?

For a head fixed animal, how stable is the current state-of-the-art whole cell recording from a cortical neuron? The animal's breathing, and heart beat must move the neuron relative to the recording ...
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40 views

Converting fmri data to association matrix

I am currently working on a new tool for the analysis of (large) weighted networks. Association matrices (correlation matrices) as obtained from fMRI data are perfect examples of the kind of data I am ...
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46 views

Does the Jungian notion of collective unconsciousness have any legitimacy in the light of modern neurobiology and epigenetics?

Carl Jung has long ago proposed a rather controversial notion of collective unconsciousness [1, 2, 3], a form of the unconscious (that part of the mind containing memories and impulses of which ...
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26 views

What is the mechanism responsible for the 'delay' in delayed rectifier potassium channels?

I've been trying to find a comprehensive explanation concerning the nature of the 'delay' in neurons' delayed rectifier potassium channels. As it's written in my intro to neuroscience textbook, these ...
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0answers
37 views

Biology Experiment Data (Hodgkin-Huxley)

I'm doing research into the Hodgkin-Huxley Model from an electronics/mathematics perspective and I'm looking to find actual numerical results from experiments on squid axons. I want to compare the ...
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54 views

What causes headaches (biologically)? What does it mean directly? [closed]

Even though your brain can't feel pain, thingies in your head are installed to compensate for that. Once I thought your head starts to hurt when your brain is tired. I can't believe this any more. ...
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1answer
74 views

Exercise vs stimulants, which is more effective for promoting concentration?

Stimulants are the first choice for treating ADHD. But we also know that exercise helps to improve concentration. We know that both stimulants and exercise increase bloodflow to muscles and to the ...
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1answer
33 views

The use of proteins in memory creation

I have very limited knowledge of how the human memory works as I think, at this time, most people do. However, I have been reading and some articles which say, and I quote the article just linked ...
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1answer
67 views

What is the energy consumption of the brain?

What is the energy consumption of the brain, and is there a difference in consumption when waking and sleeping?
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151 views

Saltatory Conduction Of Nerve Impulses

I am aware about some basics of Saltatory conduction of nerve impulses. I know that the nerve impulses(ionic flow and the depolarization) are transferred from the node to the node in myelinated nerve ...
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23 views

What features cause mechano sensory adaptation?

In relation to mechanoreceptors (e.g. pacinian corpuscles), what stops a constant stimulus from producing action potentials? I understand that adaption is used to filter out stimuli that aren't ...
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66 views

Organisms with the most extreme sensory capabilities? (sight, smell, sound) [closed]

Background It is quite mind boggling to imagine what it would be like to be missing sight, sound, touch, smell, taste etc. Question Which organism holds the record for most extreme sensory ...
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47 views

Nocioception (pain perception) in subcutaneous tissue

There seem to be no nocioceptors (pain and temperature sensitive nerve endings) in subcutaneous fat. there are nocioceptors and other receptors in veins running through fat, but these can be avoided. ...
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97 views

How long does Lentivirus take to express in vivo mouse neurons?

Does anyone know how long it takes for a standard Lentivirus vector to express its genes (under a strong promoter such as CAG, CB7, etc.), after injection into the brain of a mouse? By hearsay I ...
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3answers
203 views

Action Potential Distribution On Synapses

This is a biology+physics question. Since there is no biology section, I am asking here. In brain, when a neuron reaches to threshold value, it fires an action potential. In most graphics, that is ...
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1answer
114 views

Molecules and human memory

Has it been demonstrated that the memory of human brain is just connections between neurons, not "long" molecules such as RNA or proteins?
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57 views

What do nerves have to do with feeling nervous?

I was thinking about how when people say: "Nerve cells don't regenerate" (which is, apparently, not true at least for some kinds of nerves) and "You're making me nervous" they might not refer to the ...
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1answer
51 views

Are there neuronal firing artifacts produced by head movement?

I'm experimenting with a consumer-grade ElectroEncephaloGram (EEG) sensor and have created the image below using the device. Because the sensor on the device does not use a suction cup, there are a ...
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4answers
68 views

Are neural connections one-way?

I'm trying to think about how two neurons communicate, typically shown in pictures as an electric pulse traveling along a long, thin connective tissue. Is this depiction somewhat accurate, and if so, ...
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1answer
58 views

Is it possible for neurons themselves to manifest cancerous behavior?

From what I understand, one form of cancer is a faulty gene responsible for the programmed death of a cell. Not long ago, popular wisdom used to say neurons don't regenerate. However that is no ...
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220 views

L1 - L5 layers of the brain

I have read in some papers about the layers L1-L5 of the brain (e.g. in this paper). I could not find a definition of these layers. I have found information about the layers V1-V5 in the visual ...
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1answer
51 views

Does sympathetic nervous system acts bilaterally for pupil dilation or other two sided organs?

The question might seem weird. Does sympathetic nervous system acts 'bilaterally' meaning if you shout to a person's left ear a loud noise (e.g. by headphones), will it activate sympathetic system ...
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1answer
22 views

Is the brain functionally symmetrical?

I understand that each half of the human brain handles different parts of our thinking. Left brain, right brain, that whole topic. But in pictures, the brain is always depicted as having symmetrical ...
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1answer
60 views

Alpha wave frequency variance in EEG of single subject over period of a few hours?

I have an Emotiv EPOC (EEG headset: 128 SPS, notch filter @60 Hz, felt saline contacts) I've been playing around with. Over the course of two or three hours using CCA to plot an SNR contour against ...
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1answer
389 views

What is 'calcium conductance'?

What is the meaning of calcium conductance in ion channels. I encountered this in the following text: It was established that the µ and δ opioid receptors open potassium channels, which results ...
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1answer
25 views

Confusion over role of current/potential in Nervous system?

I am taking a course on the nervous system and I am do not have any physics background. Therefore, I would like to know, what are we precisely talking about when we talk about current in the nervous ...
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1answer
60 views

Do ants feel pain?

I have watched video on youtube where guy pours molten aluminium into fire ant colony to make casing. In the comments below there's huge discussion on is that a right thing to do. I am on the side ...
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1answer
79 views

What is the difference between clinical and non-clinical depression, and is there a term for different severity of the bipolar disorder?

I was looking for a term which describes a bipolar disorder of lesser severity. I know from experience from someone I know well, what a very severe case of the bipolar disorder looks like, when an ...
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1answer
44 views

What could cause no pain but sense of touch?

What could cause a mammal to have and respond to a sense of touch with only isolated numbness but not feel pain?
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1answer
48 views

Measurement of glucose concentration in the human brain

If I want to measure the exact glucose concentration in a human brain then how can I proceed to do that? Is there any technique or assay to do that?
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1answer
29 views

Specifics of decussation

Beginner question here: The definition of decussation I see is the crossing through the midline of a bunch of neurons. But I was wondering if there was a little more to it than this, because I'm ...
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1answer
36 views

Nervous System : Organ or Gland Failure

If an organ was to start failing, not total failure, such as the thyroid gland, is it possible that the fault may not lie in the failure of the organ but in the nerve signals coming from the brain?
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35 views

Nervous system : Nerve signals [duplicate]

If the electrical signals from all the various organs throughout the body eventually connect to the nerves in the spinal column traveling up to the brain, how does the brain differentiate the ...
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45 views

Is there a scientific name for the field of study focusing on the hemispheres of the brain and their control of opposite sides of the body?

I'm assuming this field of study would focus on motor controls, movement, and exercise, but it could also focus on activities which strengthen the corpus callosum or stimulate a specific half of the ...
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1answer
71 views

Evolution, self organization and neuroscience

I have rudimentary knowledge of evolution, and biology in general, so bear with me if this question is a bit naive. Let's say we have a particular trait, like highly sensitive peripheral vision. ...
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1answer
154 views

If people with colorblindness lack one type of cone cells, shouldn't they be unable to recognize one particular color?

The 3 types of cone cells in normal humans allow them to view 3 types of colors and any color made from mixing and matching those 3. So, 2 types of cone cells should only allow to view just 2 types ...
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1answer
92 views

Is Nerve Growth Factor (NGF) commercially available?

I'm curious if NGF, or Neurotrophins in general is available commercially. Can I order it online? If not, what are the medical/biological reasons. Does it breakdown quickly after synthesis/capture? Is ...
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2answers
101 views

Inverse of dopamine reuptake inhibitor?

The wikipedia article on the dopamine transporter gives examples of some drugs whose effects are mediated by the inhibition of the dopamine transporter, such as cocaine and amphetamines. Are there ...
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1answer
33 views

Could silicon oil block Na+ ion channels in the membrane of an axon and prevent Na+ influx?

Could silicon oil block Na+ ion channels in the membrane of an axon and prevent Na+ influx? I have been wondering if Na+ influx could have been a diluting factor in anterograde fills. If so, could ...
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1answer
2k views

How do dopamine agonists like amphetamine/methylphenidate affect acetylcholine signalling?

Do they increase it, or is the effect mostly neutral?
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42 views

Satisfication with irrelevant things [closed]

I am not sure if this question is better suited CogSci.SE so please tell me. My question is why are we satisfied when we get things that aren't useful in any important way? For example, relating to ...