The study of the structure and function of the nervous system and its components.

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Inverse of dopamine reuptake inhibitor?

The wikipedia article on the dopamine transporter gives examples of some drugs whose effects are mediated by the inhibition of the dopamine transporter, such as cocaine and amphetamines. Are there ...
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1answer
33 views

Could silicon oil block Na+ ion channels in the membrane of an axon and prevent Na+ influx?

Could silicon oil block Na+ ion channels in the membrane of an axon and prevent Na+ influx? I have been wondering if Na+ influx could have been a diluting factor in anterograde fills. If so, could ...
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2k views

How do dopamine agonists like amphetamine/methylphenidate affect acetylcholine signalling?

Do they increase it, or is the effect mostly neutral?
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1answer
73 views

Simultaneously using both hands - How does that work?

Is some part in one hemisphere the decision maker and "calling the shots" - controlling the opposite side's hand "directly" and controlling its own side's hand through the corpus callosum. Or: is ...
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1answer
29 views

Fastest and slowest action potential

When our instructor asked us about the speed of action potentials in cells, I told him that action potentials and two-wheelers travels at similar speeds. He thought that this is an 'interesting' way ...
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1answer
53 views

Relationship between action potentials and EEG recordings

It is possible that I am overthinking this but I have difficulties relating the neural activation to the amplitude and frequency of EEG recordings. For example; if at the EEG location P3/P4 we ...
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1answer
38 views

Neurology: spinal tract

I have had a few difficulties finding answers for the questions below. I have tried answering the first two myself; but, I am not sure they are correct or not. And I am not too sure about the third ...
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1answer
43 views

Nervous system: Pain and Pleasure?

If you have a constant pain in your body, why does a greater pain or pleasure make you not feel the original pain?
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1answer
46 views

Do's and Don't's of Undergraduate Research? [closed]

I was fortunate enough to get a position as a researcher for the Mayo Clinic's SURF Program this year. My PI's lab focus is on the the immune system's role in CNS axonal and neuronal injury, ...
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1answer
93 views

Studying the fruitfly nervous system

I'm studying Neuroscience and Fruit Flies are a pretty big deal but I don't know as much as I think I should about them. Are there and comprehensive sources that I could read? I'd like a review of ...
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1answer
66 views

What in neurons and their connections changes during the process of learning?

I'm not sure if this question belongs more in physics or biology (or maybe even computer science)... but biology seemed to fit more. What changes in the state of our brains when we learn things? ...
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1answer
60 views

Radial Basis Function Network (RBF Network)

In the Wikipedia article on radial basis function network, I didn't understand what was meant by "center vector for neuron i", in other words "center of the RBF units called also prototype".
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1answer
281 views

What is the physiological difference between snorting/swallowing cocaine

I know that mucosa inside the nose absorbs cocaine molecules when snorting cocaine, but what difference is there compared to swallowing? Also more cocaine administration equals more cocaine molecules ...
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5k views

What are the functions and differences between axons and dendrites?

My textbook doesn't do a very good job of pointing out what the differences between the two are. It basically mentions axons only in the same breath as the synapse (that synapses are the endings/tips ...
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1answer
76 views

Eye Brain Mapping

If our eyes are separated by some kind of full proof barrier/isolation, is it possible that our brain can picture/visualize two different pictures at a time? How the brain will function in this ...
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1answer
119 views

Do nerve cells cause action potential in cardiac muscle?

I think the answer is no, but I am not 100% sure. If it was yes, then the dendrite of the nerve cell should each time receive a stimulus causing Na+ channels to open, when the contraction happen. ...
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1answer
127 views

How do axon terminals report to the soma?

It is important to bear in mind that the distance between a neuron's axon terminal and its soma can be extensive, up to about 1m in the human body. The fastest transport along the axon is 400mm/day ...
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1answer
53 views

Are there any neurotransmitters that trigger all neurons?

I'm reading into the basics of the nervous system, and am intrigued by neurotransmitters. I understand that certain neurotransmitters can trigger more than one neuron type, and may be used as ...
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1answer
1k views

Serotonin - Does being aroused make you sleepy?

My Psychology text book says Serotonin causes "Sleep, arousal levels and emotion" Does this really mean that when you are being aroused, Serotonin is released, which in turn makes you sleepy? If so, ...
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1answer
145 views

What is the biochemical reason for mental fatigue?

Is it known exactly why the brain needs sleep? What's dropping low / going high when we experience mental fatigue? I can see why low glucose could result in mental fatigue, are other reasons known?
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1answer
965 views

What are the positive and negative effects of insulin on cognitive function?

A UCLA study seems to imply that insulin interferes with cognitive function. The DHA-deprived rats also developed signs of resistance to insulin, a hormone that controls blood sugar and ...
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0answers
13 views

What keeps resting potential of neurons constant at -70mV?

I know the sodium-potassium pump pumps out 3 Na+ ions and pumps in 2 K+ ions per reaction so the negative charge in the axon increases. However, once the voltage (difference of charge inside and ...
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28 views

Kinesin-5 / cytoplasmic dynein spatial density distribution in neurons

is there some way to experimentally determine the density distribution of those two molecular motors in a Neuron? Fluorescence labeling would be impossible(?) as GFP markers would probably alter the ...
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0answers
128 views

In-Ear headphones increasing nasal breathing resistance

I figure this is a rather strange question, however, I noticed this quite some time ago and wanted to make sure that this is in fact a permanent condition before posting. The situation is as follows: ...
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0answers
23 views

Neuroscience: zapping an axon connected to thermoreceptor

Let’s say an experimenter has an electrode that can give a shock to a single axon. She takes that electrode and zaps an axon connected to thermoreceptors in the hand of her subject. I) What would the ...
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25 views

Systematic anticoagulant injection after a CVA

Since most of the cerebrovascular accident are ischemic ones, would it be usefull to have anticoagulant everywhere (we already have AEDs everywhere) so that everytime someone would have symptoms of a ...
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0answers
70 views

Why are there different types of neurotransmitters?

Why does the type of neurotransmitter matter? If the neurotransmitter just stimulates a dendrite on a neuron which causes electricity to move through via sodium-pottasium pumps and ion gates to ...
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0answers
86 views

Learning first-year biology + anatomy via documentary? [closed]

Probably going to take first-year biology in ~4 months; so was thinking to go through MIT's 7.00x on EdX… However seeing at how popular this topic is, I was thinking there might be a fun documentary ...
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77 views

Unexplained pain in the legs at night, possibly due to peripheral nerves - diagnosis and cure? [closed]

I have seen a few instances where people suffer from tremendous pain the legs, often around the region of ankle, going a bit down and stretching up to knee. This happens most prominently at the night ...
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43 views

Does pain scale with mammal mass?

Some biological features scale with the animal mass (see previous Q&A). Assuming the same concentration of nociceptors on the skin surface, I'm wondering how painful a 1 cm wound will be ...
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136 views

Does brain activity generate heat gradients in the brain?

I'm reading this article on guiding axon growth using temperature gradient, and it mentions that the trajectory of growth of neuron connections can be influenced by temperature gradients as little as ...
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0answers
35 views

Hippocampal regulation of hypothalamus

What is the difference between CA1-CA4 hippocampal subfields and dentate gyrus (DG) in negative regulation of hypothalamus? I`ve found only evidence that GR expression is more in CA1-2 and DG, while ...
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174 views

Does sexual arousal inhibit functions of prefrontal cortex in human females as well as males?

I've read somewhere, that when a human male experiences sexual arousal, his prefrontal cortex and, hence, his ability to reason and make rational decisions, is being heavily inhibited. Sounds pretty ...
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0answers
61 views

Carrying or packaging capacity of SAD B19 dG rabies virus

I'm wondering about the carrying capacity also referred to packaging capacity or loading capacity (how many base pairs can be packed efficiently into virions) of the pseudotyped rabies virus SAD-dG as ...
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19 views

Which Receptors are involved in Psychedelia/Psychosis?

Which receptors are involved in Psychedelia/Psychosis? I know that the 5-HT2A, 5-HT3, D2, κ-opioid and NMDA receptors are likely involved in psychosis.
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51 views

The relationship between the currents of intracellular and extracellular ions of a cell

In a cell, assume that only sodium, potassium, chloride and calcium ions can cross the membrane and their currents are: $I_{Na}$, $I_{K}$, $I_{Cl}$ and $I_{Ca}$, across the whole membrane. There is ...
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52 views

Does Dorsal Raphe Nuclei firing pattern change in response to voluntary breathing?

I'm reading this paper, which discusses how Serotonin may be involved in motor functions of mammals: 5-HT and motor control: a hypothesis . The paper includes the following diagram of the Dorsal ...
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1answer
86 views

Does the Parasympathetic Tract of Colon Sigmoideum Travel with Nervus Vagus and its Nucleus Dorsalis Nervi Vagi?

I have the following tractus now: nucleus parasymphaticus sacrales -> nervus splanchnic -> ganglion terminalis -> colon sigmoideum The tract is parasympathetic. It suggests me that it should ...
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1answer
291 views

Does one neurotransmitter travel all the way through the nervous system?

Nerve impulses of course go really fast, but the neurotransmitters have to travel through millions of nerves, so how can it go that fast? Is it a sort of relay with lots of neurotransmitters taking ...
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1answer
258 views

Least painful way to die

There is a lot of talk about inhumane treatment of animals and how we don't kill them in the proper way. I wonder how much research is done on this subject. What is the overall least painful way for ...
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2answers
113 views

Chills down the spine with certain music?

I am sure many of us know the feeling of that tingling chill down our spines when listening to certain music. I experienced this most when my younger brother played an emotional piano piece for a ...
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1answer
38 views

What is accumulation and release centre of neurohormones?

What is accumulation and release centre of neurohormones? Is it hypothalamus?
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68 views

Systemic sensory confusion?

Sometimes when a person gets touched on one part of the body they feel it else where and may think it came from a different part of the body. What causes this? Other examples are similar to why you ...
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2answers
89 views

Epinephrine vs. Adrenaline

Both names are widely used, with what appears to me as a slight prevalence of “epinephrine” in scientific literature and an overwhelming prevalence of “adrenaline” in popular media. Are there any ...
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1answer
48 views

How do neurons send electric pulses even though they are surrounded by liquid which is mostly water?

I just thought about the fact that people move through electrical pulses traveling through neurons in the brain and muscles through the body. Here is what i know: the body is full of 97 or more, ...
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1answer
76 views

Is Nerve Growth Factor (NGF) commercially available?

I'm curious if NGF, or Neurotrophins in general is available commercially. Can I order it online? If not, what are the medical/biological reasons. Does it breakdown quickly after synthesis/capture? Is ...
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1answer
79 views

If inhibiting S6 kinase decreases protein translation, then could inhibiting S6 kinase could possibly slow down long-term potentiation in neurons?

From http://en.wikipedia.org/wiki/P70S6_kinase... Phosphorylation of S6 induces protein synthesis at the ribosome. P70S6 kinase is in a signaling pathway that includes mTOR (the mammalian ...
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1answer
8k views

How reversible is decerebrate posturing caused by brain stem damage?

This is a follow-up question to How likely would Abraham Lincoln be to survive his wounds today? You don't have to see a CT scan or autopsy to know if the brainstem is injured (directly or ...
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1answer
57 views

Is it possible to convert nerve signals or electrical activity into a readable format? [closed]

Can we have the technology to recreate the informations (like images, sounds etc.)[as in the form of signals in our mind] from human mind to human understandable format? In short, can we read human ...
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1answer
41 views

Mechanism of antiperistalsis

What is the mechanism of antiperistalsis that occurs during vomiting? Why the peristaltic waves normally don't propagate in anal to oral direction? Please give logical explanation with authentic ...