The study of the structure and function of the nervous system and its components.

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Hodgin-Huxley model for a single neuron - continuation

As continuation to This question I have posted. Another set of questions is given for the same model : This time it is also given that for $t<0$ the membrane potential is $u_0$, and at $t=0$ it ...
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1answer
90 views

Do both Carbamazepinum and Lamotriginum increase glutamate threshold?

I have in my notes that: Carbamazepinum increases threshold for glutamate Lamotriginum delays release of glutamic acid I would like to simplify these sentences into a single line. I would like to ...
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1answer
73 views

Does breathing air containing 3% carbon dioxide gives you a headache?

As far as I know, breathing air containing relatively high levels of CO2 may get you a headache. I also know that CO2 level in the fruit bodies of peppers can reach levels as high as 3% at certain ...
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45 views

What controls gut motility?

I have two different papers. One claims that gut motility is reduced by stimulation of the Opioid κ and δ receptors. The receptors are activated by Morphine and certain derivatives, specifically ...
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1k views

What is the mechanism of reflex arcs?

When a reflex arc occurs the signal from the receptor passes straight to the motor neuron instead of being passed onto the brain. This is a rather simplistic explanation, I was hoping to make it more ...
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34 views

How isolated are different areas of the brain?

I'm interested in understanding how isolated different parts of the brain are from each-other. I'm trying to understand the way that different sections of the brain work together. More specifically, ...
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62 views

Is severe but short-term pain worse than moderate but prolonged pain for the body?

I'm wondering about the effects of different durations and intensities of pain on the body. So the two can be compared, let's say that the cause of pain is the same in both cases, but in one the ...
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143 views

Is an Eidetic Memory (or other unusual forms of memory) less susceptible to anterograde amnesia?

I'm a physicist, so as a fellow scientist I want to apologize because this question will be entirely based on anecdotal inferences and I am well aware how irritating that can be. I have an eidetic ...
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185 views

Inductance in cell

In an animal cell, especially neuron and in particular its axon, while there is electrical resistance and capacitance mechanism in the cell, which play essential roles in the cable theory model of ...
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109 views

Do insomniacs yawn?

According to wikipedia, the jury is still out on the function a yawn serves. The article referenced above however writes to say Yawning most often occurs in adults immediately before and after ...
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64 views

Spinal cord injury bypass

When the spinal cord is damaged, the connection between the brain and some part of the body may be lost. To restore this connection, researches are considering either: Repairing the damaged area so ...
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79 views

Evolution, self organization and neuroscience

I have rudimentary knowledge of evolution, and biology in general, so bear with me if this question is a bit naive. Let's say we have a particular trait, like highly sensitive peripheral vision. ...
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158 views

Does neuroeconomics study the brain or study economics?

I'm trying to understand what neuroeconomics is. There are two possibilities for what it might mean. (1) The study of cognitive processes in the brain by applying basic principles of economic theory ...
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282 views

What areas of the brain are involved in doing arithmetic operations?

Do neuroscientists already know what areas of the brain are involved in mental calculations? Has any fruitful research been done on that or not yet? Do you think that if we understand what areas of ...
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302 views

Why do I see an inverted image of an object when I close my eyes?

If I stare at an object for a long time and close my eyes, at first I can still see the object with my eyes closed. But the image I see with my eyes closed is inverted: dark colors appear as light and ...
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94 views

Carrying or packaging capacity of SAD B19 dG rabies virus

I'm wondering about the carrying capacity also referred to packaging capacity or loading capacity (how many base pairs can be packed efficiently into virions) of the pseudotyped rabies virus SAD-dG as ...
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366 views

What is the biochemical reason for mental fatigue?

Is it known exactly why the brain needs sleep? What's dropping low / going high when we experience mental fatigue? I can see why low glucose could result in mental fatigue, are other reasons known?
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42 views

How are physiological reversal potentials (or ion concentrations) of neurons measured?

Patch clamp electrophysiology experiments typically use an intracellular solution that mimics the ionic concentrations of neuronal cytosol. At the same time, the extracellular solution is meant to ...
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41 views

What kind of changes “stays” in the neuron after the nervous impulse happened?

I often see in neuroscience textbooks about how the brain controls everything in the body with different tracts and etc, and it seems that information is always being transmitted, like there's no ...
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61 views

Dreaming after passing out

I'll have few questions about passing out and dreaming. English is not my native language, and my biology knowledge is very limited. So bear with me. What exactly is blackout? (in a really simple ...
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78 views

All-trans-retinal being converted back to 11-cis-retinal or vitamin A

There are two pathways all-trans-retinal can take after detaching from the scotopsin: (1) it can convert back to 11-cis-retinal, or (2) it can convert to all-trans-retinol (form of vitamin A), which ...
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24 views

Typical neuronal firing rates across the human cerebral cortex

I would like to find a scientific article (or articles), which would summarize typical neuronal firing rates in different parts of the human cerebral cortex. Any good references on this?
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42 views

Are there emotions that motivate pattern completion? If so, where in the brain are they located?

I have been studying musical "tension." Musical tension essentially refers to the "expectations" one builds up in a melody that are then "released" when a stimulus matching the expectation occurs. For ...
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178 views

Biological implementation of convolutional neural networks

In computer science, 'convolutional neural networks' are used, that are meant to be inspired by biological network structures like found in the human brain visual cortex. In the computer ...
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91 views

Anatomy of nervous system's sensory pathways

When I touch my hand on a hot stove, I feel pain. I'm interested in knowing all the main "endpoints" (components/parts of the body) that are involved in relaying this pain signal. As I understand it ...
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2answers
124 views

Converting fmri data to association matrix

I am currently working on a new tool for the analysis of (large) weighted networks. Association matrices (correlation matrices) as obtained from fMRI data are perfect examples of the kind of data I am ...
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1answer
166 views

A subtle test for color-blindness [closed]

Is there a test method of proving a person being color-blind, without letting the test subject know, that he/she is being tested? E.g. showing the person cards with colored dots like depicted here is ...
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134 views

Does Spinning dancer has anything to do with your eyesight

I came across the spinning dancer as part of the brain test to determine left brain vs right brain dominance. I saw the dancer is turning clockwise. The other people around me saw it turning ...
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74 views

What can myelination tell you about the evolution of sensory receptors?

I am reading Avi Chaudhuri's Fundamentals of Sensory Perception and wondering if the information given about the somatosensory system could tell us anything about the way it evolved. It seems (at ...
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47 views

Kinesin-5 / cytoplasmic dynein spatial density distribution in neurons

Is there some way to experimentally determine the density distribution of Kinesin and Dynein in a Neuron? Fluorescence labeling would be impossible(?) as GFP markers would probably alter the motor ...
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219 views

Relationship between action potentials and EEG recordings

It is possible that I am overthinking this but I have difficulties relating the neural activation to the amplitude and frequency of EEG recordings. For example; if at the EEG location P3/P4 we ...
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1answer
45 views

Neuroscience: zapping an axon connected to thermoreceptor

Let’s say an experimenter has an electrode that can give a shock to a single axon. She takes that electrode and zaps an axon connected to thermoreceptors in the hand of her subject. I) What would the ...
2
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1answer
46 views

What's the best way to measure/calculate the size of a light beam at the sample of a microscope?

I am using a microscope with an LED derived light through the epi-fluorescent port of a microscope. I know that the "field of view" for a given objective is equal to the field number/magnification ...
2
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1answer
242 views

Solubility of Forskolin in ethanol

I am interested in using forskolin in cell culture medium. Does anyone know how to make solution of 10 microM forskolin in 5% ethanol or less. I would like to avoid using DMSO as a solvent. Thank you. ...
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90 views

What happens during a Raynauds episode?

Raynaud's phenomenon can be a serious health issue, as the blood flow to the extremities, mainly the fingers is compromised, causing fingers to blanche, and then turn blue. Severe Raynaud's can cause ...
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2k views

What is the physiological difference between snorting/swallowing cocaine

I know that mucosa inside the nose absorbs cocaine molecules when snorting cocaine, but what difference is there compared to swallowing? Also more cocaine administration equals more cocaine molecules ...
2
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180 views

What is the full name of E. G. Gray?

E. G. Gray is Neuro scientist who found and described first the two major morphologically defined synapse types (Gray Type I (asymmetric) and II (symmetric)) in his work E G Gray (Oct. 1959). “Axo-...
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123 views

Do people with colorblindness have less cones or no cones of a certain type?

https://en.wikipedia.org/wiki/Color_blindness#Red.E2.80.93green_color_blindness Protanopia (1% of males): Lacking the long-wavelength sensitive retinal cones, Deuteranopia (1% of males): ...
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84 views

Eye Brain Mapping

If our eyes are separated by some kind of full proof barrier/isolation, is it possible that our brain can picture/visualize two different pictures at a time? How the brain will function in this ...
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173 views

Do nerve cells cause action potential in cardiac muscle?

I think the answer is no, but I am not 100% sure. If it was yes, then the dendrite of the nerve cell should each time receive a stimulus causing Na+ channels to open, when the contraction happen. ...
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4k views

Serotonin - Does being aroused make you sleepy?

My Psychology text book says Serotonin causes "Sleep, arousal levels and emotion" Does this really mean that when you are being aroused, Serotonin is released, which in turn makes you sleepy? If so, ...
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172 views

In scuba diving, are nitrogen narcosis and high pressure nervous syndrome the same thing?

In training for scuba diving, they tell you that when you're bellow 100 ft or so you have to watch out for changes in mental state that resemble drunkenness. The cause of these mental disturbances is ...
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178 views

How stable is in vivo whole cell patch clamping?

For a head fixed animal, how stable is the current state-of-the-art whole cell recording from a cortical neuron? The animal's breathing, and heart beat must move the neuron relative to the recording ...
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1k views

What are the positive and negative effects of insulin on cognitive function?

A UCLA study seems to imply that insulin interferes with cognitive function. The DHA-deprived rats also developed signs of resistance to insulin, a hormone that controls blood sugar and ...
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27 views

Nerve endings on the skin

We can perceive sensation of pain if we are poked on any part of the skin. Does this mean there is a nerve ending at every point on the skin? Does this also mean that each of these nerves go all ...
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29 views

What are tail currents?

This is a voltage clamp on an ion channel. When the voltage is stopped there is a still a current at the end (the tail current). I understand that the gates aren't completely closed because of which ...
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16 views

Why do fishes have both a gustatory and an olfactory system?

I would like to know if there is a know reason for which fishes (and many aquatic species) have both an olfactory and a gustatory system. As far as I know, in all fish species the chemoreceptors, ...
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34 views

Transcranial Magnetic Stimulation on science fair [closed]

My friends and I would love to make a TMS machine and apply it to make famous "god helmet". We know that magnetic stimulation may cause visions of angels, gods etc. My question is: what are the ...
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Pearson correlation of neural responses with it's linear estimation

I am trying to anderstand the following fact from this article (page 13): How can single neurons predict behavior Suppose I have a linear estimation of a stimulus: $ \hat{s} = \mathbf{w}^T(\mathbf{r} ...
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How do the connections from V1 to V2 form during early development of the human brain?

I am wondering how corticocortical efferents from layer I and II in V1 develop to forward visual information to layer IV in V2. Is there topology preservation in these connections from the beginning ...