The study of the structure and function of the nervous system and its components.

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17
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2answers
524 views

Can parts of a human brain be asleep independently of each other, or vary in the times required for them to fall asleep?

I know that some birds and marine animals can continue complicated activity (swimming, flying?) while one hemisphere of their brain is asleep. I'm interested if human brain has some parts of it that ...
-2
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0answers
11 views

How does the brain develop different parts? [on hold]

The mammalian brain contains many parts which perform specialized functions. However, the actual mechanical makeup (neurons) are mostly homogenous throughout the brain. After a brain achieves ...
3
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1answer
39 views

What are tail currents?

This is a voltage clamp on an ion channel. When the voltage is stopped there is a still a current at the end (the tail current). I understand that the gates aren't completely closed because of which ...
1
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0answers
28 views

Forgot to cool slides before washing

I just finished an immunofluorescence experiment and I'm wondering what went wrong. The tissues seem dimmer than they should be. One mistake I made was: I completed the antigen retrieval step, in a ...
3
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1answer
2k views

What happens in your brain when you receive information which causes you to bristle?

I'm talking about moments when you watch a film and you bristle, or when you listen to music, etc. What kind of neurotransmitter flow changes?
14
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1answer
152 views

What's the mechanism for being mentally tired?

I notice that after long tests, or long periods of critical thinking, my body and mind feel noticeably tired. Why does this happen? Are the neurons in my head not firing as quickly, or is there just a ...
16
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2answers
147 views

What are the main mechanisms of interaction between the nervous and immune systems?

We know from pop science that our psychological states have an effect on our immune systems ("worrying ourselves sick", etc.), but what are the actual mechanisms through which our nervous systems pass ...
0
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0answers
5 views

Feedback mechanisms for the dynorphin-kappa opioid system?

(this is all happening in the brain). Also it's best to go context-first I think (1) Normally if you take an agonist drug that hits a receptor "x", eventually the brain will downregulate the density ...
5
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1answer
60 views

Why are so many recreational drugs serotonin 5-HT1A partial agonists?

I found out that many psychoactive drugs partially activate the 5HT1A receptor. Looking at Wikipedia, these include MDMA, LSD, CBD, Psliocybin/Psilocin, amphetamine and various other psychedelics, and ...
0
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0answers
26 views

How does stimulus reach neural threshold?

I understand that when the stimulus into a neuron is greater than the threshold it triggers the action potential. Do all the contributing stimulus have to occur at the same time, or can they occur ...
1
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1answer
64 views

How do heredity and regression to the mean work with respect to intelligence?

I am trying to understand the heredity of intelligence between generations in general, and how regression to the mean works in detail in particular. The answer I'm looking for should preferably answer ...
4
votes
1answer
79 views

Is there a biological explanation for perceived deeper cognition whilst on cannabis?

Cannabis has been associated with literature, arts, and culture for centuries. There are a few features of the drugs affect on the human mind that account for this, however it remains illegal in most ...
5
votes
2answers
317 views

What is the biological principle of this “holotropic breathwork” technique?

Holotropic breathwork is a non-drug technique developed by Stanislav Grof used in psychotherapy. The therapy as a whole is usually called holotropic breathwork (at least by Grof himself) and will most ...
0
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0answers
43 views

Is there an evolutionary advantage associated with migraine? [duplicate]

I have read Wikipedia article on Genetics of migraine headaches and I don't buy it Because genetics influence susceptibility to migraine, it can be shaped by evolution. Fitness-impairing ...
3
votes
2answers
69 views

What neurons make up the CNS?

I generally see it written that there are three types of neurons, classified by projection: (1) sensory neurons, (2) interneurons, and (3) motor neurons. Now, in the CNS, I don’t think there would be ...
2
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0answers
29 views

Nerve endings on the skin

We can perceive sensation of pain if we are poked on any part of the skin. Does this mean there is a nerve ending at every point on the skin? Does this also mean that each of these nerves go all ...
3
votes
2answers
62 views

Why do typical acetylcholinesterase inhibitors (like carbamates) have a greater parasympathetic effect than a sympathetic effect?

I understand that the post-ganglionic neurones of the sympathetic system are adrenergic, but surely these neurones will be excited to the same extent as the parasympathetic post-ganglionic neurones (...
0
votes
1answer
53 views

Where exactly is pleasure

Question from an outsider: have we been able to pinpoint where exactly the feeling of pleasure comes from? I know that there are several types of pleasure, I'm talking about the 'liking'. If that ...
2
votes
1answer
219 views

Relationship between action potentials and EEG recordings

It is possible that I am overthinking this but I have difficulties relating the neural activation to the amplitude and frequency of EEG recordings. For example; if at the EEG location P3/P4 we ...
1
vote
1answer
112 views

Alpha wave frequency variance in EEG of single subject over period of a few hours?

I have an Emotiv EPOC (EEG headset: 128 SPS, notch filter @60 Hz, felt saline contacts) I've been playing around with. Over the course of two or three hours using CCA to plot an SNR contour against ...
5
votes
2answers
72 views

How does the brain know what to remember and what not?

People remember some information for example when learning for an exam, or remember to go to a shop after work etc., but we don't remember usually much other stuff like people passing us, what was the ...
3
votes
1answer
58 views

Do all different types of neurons serve different roles?

I know from my basic education in neurology that the brain has various sorts of neurons. These are usually bunched into 3 different categories (sensory, moto and interneurons). I read in a recently ...
1
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1answer
33 views

What information do bipolar cells encode?

Short version: I don't see what information on-centre bipolar cells are actually capturing. Longer: Actually, the question could be extended to on-centre retinal cells as well, but I'll focus on ...
13
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4answers
1k views

Is it possible to feel pain in some part of a body, but the pain “feeling” is introduced somewhere else?

Is it possible to feel pain in some part of a body, but that the cause of the pain is situated elsewhere in the body? For example, somebody feels pain in his toe, but it turns out that this pain is ...
1
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0answers
46 views

What happens to the human brain when unconscious?

What part of the brain gets affected and does it harm the brain? Thank you I just needed some extra info for a video I'm making.
1
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1answer
23 views

Voltage sensitive dyes technique: What is the underlying measure?

I just discovered voltage sensitive dyes technique: first of all what imaging techniques do we use? And I have seen that figures are labeled with ΔF/F0, what does it stands for?
9
votes
1answer
732 views

How does the brain avoid feedback loops?

The article Ants Swarm Like Brains Think really helped me to understand the way that neurons which are pretty dumb on their own (like ants) can work together to create a pretty genius system (a brain ...
6
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1answer
2k views

Why can action potentials not be initiated at dendrites?

Why are action potentials not initiated at dendrites, although dendrites are the first to receive input from the presynaptic cell? In fact, excitatory postsynaptic potentials (EPSPs) at the dendrites ...
0
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0answers
29 views

Where to go next with clustered C elegans neuronal time series

I'm doing some independent research with the C Elegans nervous system (with the OpenWorm project) and was looking for some guidance as to where I should go next. Right now, I'm dealing with calcium ...
0
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0answers
28 views

Do ion channels block at these temperatures?

I found this paper and it says nerve axons cold block at temperatures near 0C. http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.1968.sp008656/pdf Does this mean ion channels also block (due to ...
8
votes
2answers
262 views

Are unilaterally deaf people able to determine where sound comes from?

My question is on people deafened in one ear, but normal hearing in the other. Time and level differences between the two ears are only part of how the human body can localize the source of the sound....
1
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2answers
58 views

Does the creation of memory involve mRNAs crossing the synaptic gap?

There is a diagram from a book titled "Teaching with the brain in mind". The diagram shows The diagram appears to show that the "creation of memory" involves "messages coded by RNA" moving through ...
3
votes
1answer
56 views

How can neurons divide without centrioles?

I have read in my studies that neurons lack centrioles. If that is so, then how is it possible that new neurons are added to our brain? Does this have anything to do with memory loss?
5
votes
2answers
4k views

Are brain cells replaced over time?

You know how your cells die all the time and new ones are made to replace them, so you practically have a new body every maybe 5 years? Many people say you become a completely different person every ...
4
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2answers
111 views

Does caffeine actually enhance cognition?

I have heard, respectively: Caffeine measurably enhances cognitive function. Caffeine does not measurably enhance cognitive function in any significant way. Caffeine enhances cognitive function, but ...
1
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0answers
21 views

How much yogurt would one have to consume to have a noticeable effect on neurotransmitters [closed]

I read several recent articles that proposed a link between bacteria in our gut and neurotransmitters in our brain. For instance http://www.ncbi.nlm.nih.gov/m/pubmed/24997036/ I am curious how much ...
3
votes
2answers
827 views

What is the difference between clinical and non-clinical depression, and is there a term for different severity of the bipolar disorder?

I was looking for a term which describes a bipolar disorder of lesser severity. I know from experience from someone I know well, what a very severe case of the bipolar disorder looks like, when an ...
5
votes
1answer
90 views

How does the synaptic cleft exist?

I'm not asking why the synaptic cleft exists, i.e. what function it holds, rather how. So I know that the neurotransmitter diffuses across it, it is 20-40 nm wide and contains basal lamina (in NMJs at ...
2
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0answers
16 views

Why do fishes have both a gustatory and an olfactory system?

I would like to know if there is a know reason for which fishes (and many aquatic species) have both an olfactory and a gustatory system. As far as I know, in all fish species the chemoreceptors, ...
10
votes
5answers
1k views

Can the human brain be reduced to a binary system?

Does the brain really function like a computer as in, ultimately every response is related to a binary sequence based on whether particular neurons fire or not?
1
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1answer
24 views

Analysing the ERP (Event-Related Potential from EEG recordings) in terms of the P-300 wave

I am trying to understand how to analyze ERP (Event-Related Potentials) from EEG recordings in focus on P-300 waves. I have come up with a few questions which I hope you might be able to help with: ...
1
vote
1answer
39 views

Why is active transport needed in repolarization?

During the repolarization phase of an action potential, the potassium ions diffuse out of the cell, and active transport begins. What I do not understand is why active transport is needed when the ...
3
votes
1answer
108 views

Has the human body the greatest total length of nerves of all animals?

I've read that a human body contains about 150,000-180,000 km (Pakkenberg et al., 1997; 2003) of nerve wiring in the whole body. But does this length increase with the size of the animal? For example, ...
1
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2answers
55 views

At what age does the mouse skull stop growing?

Unless otherwise mandated, neuroscientific research on mice is done with ~7-week old animals. There is a sort-of mantra that at this age their skulls stop growing. However, recently, I noticed a ...
6
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2answers
223 views

Dopamine paradox in schizophrenia

If there is more dopamine action in the mesocortical pathway in schizophrenia, then schizophrenics should always be in euphoric state. Instead, schizophrenics often lack motivation and do not ...
1
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0answers
13 views

Real unipolar neurons do indeed exist in human?

I studied that the unipolar neuron in human body are not really unipolar but they're pseoudounipolar neurons. On the other hand according to what I understood from wikipedia (neuron) there are real ...
4
votes
1answer
45 views

How long does a spiking signal last?

It is surprisingly hard to find information about the timing of neurons, in particular how long an action potential can contribute to the summation of a neuron. Is it on the order of milliseconds or ...
4
votes
3answers
149 views

what is meta-sympathetic nervous system?

I always knew about the sympathetic and para-sympathetic nervous systems, and today I was told about the meta-sympathetic nervous system, but I didn't understand well the man who told me about it and ...
0
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1answer
95 views

Can multiple overt/covert intentions produce identical EEG readings?

With sophisticated techniques likes ERP, it is possible to correlate certain EEG activity with certain overt/covert actions. What I'm wondering is: is there a risk for 2+ overt/covert actions ...