The study of the structure and function of the nervous system and its components.

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2answers
93 views

Why does anxiety cause diarrhea or constipation?

Anxiety sometimes cause diarrhea, sometimes constipation, and sometimes both. It's interesting because it seems their underlying neurophysiology is somehow different. What are underlying physiological ...
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1answer
35 views

Converting fmri data to association matrix

I am currently working on a new tool for the analysis of (large) weighted networks. Association matrices (correlation matrices) as obtained from fMRI data are perfect examples of the kind of data I am ...
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0answers
122 views

How does Sodium Valproate cause neural plasticity

I have been reading a fascinating paper: Valproate reopens critical-period learning of absolute pitch 18 individuals were given Sodium Valproate (VPA) for a fortnight during which they trained on a ...
6
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0answers
72 views

effect of pupil responses on the electroretinogram

The electroretinogram is generally considered to reflect the retinal processing of a light stimulus, typically a photoreceptor response followed by secondary neuronal activity. However, I am wondering ...
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0answers
70 views

What is the limit of time resolution in fMRI?

I was reading about a few studies on estimating functional connectivity between brain areas using fMRI signals. However, as far as I know that fMRI has a very poor time resolution, roughly in the ...
4
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0answers
110 views

If D1 receptors stimulate adenylate cyclase (through GPCRs) and D2 receptors inhibit it, then why do mutations in both have similar effects?

D1 and D2 both refer to specific types of dopamine receptors. I'm sure it has something to do with the fact that the D1 receptors are in regions different from D2 receptors. I know that adenylate ...
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0answers
38 views

Single long axon vs serial neurons

Based on the comments in this post and also this chat. For discussions and speculations please comment in the chat. The basic question is what is the advantage of having a single long axon such as ...
3
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0answers
58 views

The Operation of tuning in the S1 layer of ventral model

According to my previous question in ventral Stream pathway and architecture, I want now to get a brief example about how the S1 layer is constructed. In other words, how all the simple units are ...
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0answers
44 views

Does the Jungian notion of collective unconsciousness have any legitimacy in the light of modern neurobiology and epigenetics?

Carl Jung has long ago proposed a rather controversial notion of collective unconsciousness [1, 2, 3], a form of the unconscious (that part of the mind containing memories and impulses of which ...
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0answers
37 views

Biology Experiment Data (Hodgkin-Huxley)

I'm doing research into the Hodgkin-Huxley Model from an electronics/mathematics perspective and I'm looking to find actual numerical results from experiments on squid axons. I want to compare the ...
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0answers
147 views

Saltatory Conduction Of Nerve Impulses

I am aware about some basics of Saltatory conduction of nerve impulses. I know that the nerve impulses(ionic flow and the depolarization) are transferred from the node to the node in myelinated nerve ...
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0answers
23 views

What features cause mechano sensory adaptation?

In relation to mechanoreceptors (e.g. pacinian corpuscles), what stops a constant stimulus from producing action potentials? I understand that adaption is used to filter out stimuli that aren't ...
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0answers
47 views

Nocioception (pain perception) in subcutaneous tissue

There seem to be no nocioceptors (pain and temperature sensitive nerve endings) in subcutaneous fat. there are nocioceptors and other receptors in veins running through fat, but these can be avoided. ...
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0answers
97 views

How long does Lentivirus take to express in vivo mouse neurons?

Does anyone know how long it takes for a standard Lentivirus vector to express its genes (under a strong promoter such as CAG, CB7, etc.), after injection into the brain of a mouse? By hearsay I ...
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0answers
18 views

Criteria for electrophysiological threshold

As opposed to action potential thresholds (which are yes/no events), electrophysiological thresholds of compound action potentials are arbitrary. Mostly a certain noise level is picked and when the ...
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0answers
39 views

What keeps resting potential of neurons constant at -70mV?

I know the sodium-potassium pump pumps out 3 Na+ ions and pumps in 2 K+ ions per reaction so the negative charge in the axon increases. However, once the voltage (difference of charge inside and ...
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0answers
25 views

Systematic anticoagulant injection after a CVA

Since most of the cerebrovascular accident are ischemic ones, would it be usefull to have anticoagulant everywhere (we already have AEDs everywhere) so that everytime someone would have symptoms of a ...
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0answers
48 views

Does pain scale with mammal mass?

Some biological features scale with the animal mass (see previous Q&A). Assuming the same concentration of nociceptors on the skin surface, I'm wondering how painful a 1 cm wound will be ...
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0answers
171 views

Does brain activity generate heat gradients in the brain?

I'm reading this article on guiding axon growth using temperature gradient, and it mentions that the trajectory of growth of neuron connections can be influenced by temperature gradients as little as ...
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0answers
58 views

Does Dorsal Raphe Nuclei firing pattern change in response to voluntary breathing?

I'm reading this paper, which discusses how Serotonin may be involved in motor functions of mammals: 5-HT and motor control: a hypothesis . The paper includes the following diagram of the Dorsal ...
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0answers
11 views

More vectors for inducing neurodegeneration (reduction in synaptic plasticity) in D.melanogaster

I've just finished a project on loss of synaptic plasticity in Drosophila melanogaster larvae with uas control gal4 sensor for cAMP expressed in the motor neurons. I induced neurodegeneration through ...
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0answers
19 views

Gastroenteritis virus causing mutation of the Enterochromaffin cells

I am working on the solution to a worldwide problem: IBS or chronic diarrhea following a viral gastroenteritis infection. I think I have an answer. The only missing piece to the puzzle I found in a ...
0
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0answers
36 views

MRI with lots of white matter.

Why might an MRI show a large amount of white matter and a low amount of gray matter yet have a full skull with little shrinkage in an above average intelligence primate?
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0answers
30 views

spinal cord lesion and result in somatic sensation

Jimbo suffers a lesion to the entire right half of the spinal cord at the T6 level. A few weeks after his injury, his doctor tests his right and left legs for somatic sensation and tone. fill out her ...
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0answers
24 views

Stress regulation in mosquitoes

I was just trying to understand how in insects, specifically mosquitoes does the process of emergency responding, stress regulation take place? Or in simpler words how are flight, fright and fight ...