The study of diseases, including their causes and effects.

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Why basement membrane thickens in diabetes mellitus?

Untreated diabetes mellitus may lead to blindness and kidney failure because the basement membrane of small blood vessels in these organs thickens due to increased production of collagen and laminin. ...
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Do any nonhuman species have effective ebola immunity?

I've read that ebola is an effective killer in humans because it has the ability to interrupt dendritic cells from manufacturing proteins that cause the immune system to destroy the dendritic cells ...
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Is there a Lyme disease vaccine?

Each Spring, our local health unit begins its campaign of Lyme disease and tick-bite awareness. I was wondering if there has ever been a vaccine available, and if so, what antigen does it target?
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What is the name of systemic tension of muscles?

I meat a overtrained friend (25 years old) who cannot rest. He has all muscles and most of the skin very tense. He is practising regularly in gym and sleep badly. He moves like a stick figure and has ...
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Which disorders are fully concordant?

I work in neuroscience, mostly Alzheimer's disease (AD), with some work in autism spectrum disorder (ASD). The work is in gene regulation and epigenomics. I'm familiar with monozygotic twin (MZ) ...
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Do people with gout live longer?

Antioxidants reduce damage to tissue (by scavenging the free radicals) and thus may reduce ageing.It is known that Uric acid is a very good antioxidant. People with gout have excess accumulation of ...
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Near point and far point of myopic eye

Suppose a person wears the specs of power -6D, the far point for that person is 16cm. But the near point of normal eye is 25cm. So, is the near point of a person with myopia (having far point less ...
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How was the Huntington's disease gene's location found?

I read in the book "Why we get sick." by Nesse and Williams that: Steady detective work and fabulous luck have enabled geneticists to pinpoint the Huntington's gene on the short arm of ...