The study of diseases, including their causes and effects.

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What are the limiting factors of pathogen population size in human populations?

I understand that one limiting factor in non-human animal populations is that increased pathogen populations decrease animal populations from killing them, which decreases the density of the animals, ...
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Endogenous PAF inhibitor in metastatic process (?)

When neoplastic cells cause a metastasis, they can create a protective coat of platelets that counterbalances immunitary response. My question is if the coat formed due to PAF can be undone by an ...
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Does tremor frequency generally increase as Parkinson's disease progresses?

I've been trying to research this question, but most if not all the on-line journals require costly subscription, and the studies that are posted look at tremor frequency with regards to other ...
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Wolbachia - cytoplasmic incompatibility

I read that cytoplasmic incompatibility in Wolbachia occurs when wolbachia-infected male insects mate with wolbachia-free female insects and produce non-viable offspring. By contrast, ...
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What's the relationship between Drugbank drugs and SMPDB pathways?

In the 'pathway browse' panel SMPDB pathways and their corresponding Drugbank drugs are listed. What are the relationships between the drugs and the pathways? Some listed drugs are not in the ...
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RNAi in nematode resistant plants

Background : Certain plants have been genetically engineered to have sense-antisense gene of a parasitic nematode. The dsRNA produced by the plant then inactivates the mRNA produced in the nematode, ...
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47 views

How does botulinum toxin enter the blood stream from the digestive tract?

To my understanding, large polypeptides such as botulinum toxin cannot pass the intestinal lining intact. How, then, can it enter the bloodstream and cause botulism poisoning?
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Why is the administration of exogenous Anti-D not harmful to the foetus?

Haemolytic disease of the newborn can result from Rhesus incompatibility in utero. In this disease a Rh-ve mother becomes exposed to the antigens of a Rh+ve foetus by fetomaternal haemorrhage causing ...
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Can a fungus become resistant to a chemical such as Potassium Permanganate?

A friend used potassium permanganate solution to treat tinea on the hands/feet but after some initial success, the tinea seems to be making a comeback. Could the fungus develop resistance to potassium ...
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440 views

By what mechanism does an obstructed bile duct cause excess fat in the stool?

By what mechanism does an obstructed bile duct (for example gallstones) cause steatorrhoea (excess fat in the stool)?
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Can you Transfer Cancer Between People via Saliva or other Bodily Fluids?

This may sound like a strange question. But could a Cancerous cell be transferred from one person to another from Oral contact e.g. Through Saliva, or other exchange of bodily fluids? I know that ...
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Can androgen-insensitive genetic-males get pregnant?

According to the linked report, people with androgen insensitivity syndrome appear as male, but have both feminine and masculine outer genitalia. However, I was not able to find out whether their ...
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Dynamic mutation and huntington's

I read that Huntington's is a disorder caused by dynamic mutations in the DNA, which means that a triplet sequence of DNA changes from generation to generation. Say we have the sequence ATGATGATGATG. ...
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165 views

What kind of fly is this?

I found this dude hanging out in my sink, but he didn't fly away when I put a dish in the sink. Turned out it was dead. The front part looks exactly like a housefly. But, I've never seen the back end ...
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71 views

What is the difference between influenza A and B viruses that causes their distinct seasonal patterns?

I recently learned from an answer at health.SE* that influenza B tends to occur later in the season compared to influenza A. According to the graph in that answer, during this year’s flu season the ...
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71 views

What can cause a lump in the middle of the neck? (homework case study) [closed]

What can cause an erythematous, fluctuant, nontender mass in the middle of the neck? Full Case Study: (Its the last of 6 cases and I just can't figure this one out, because of all the possibilities, ...
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130 views

Can people with paralyzed eye muscles see?

As far as I am aware, the saccades of the eye are central to visual perception. If the eye is held still, the human stops seeing, even if light is reaching the retina and the visual pathway is intact. ...
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37 views

Should gene therapy safety protocol include isolation?

In the case of a gene therapy trial where viral vectors are used to deliver genes into mammalian cells, including humans, should biosafety and ethical protocols include isolation of the patient as a ...
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43 views

Liver - Regeneration in Cirrhosis

Liver is the most resilient of the human organ (on par with or next to skin). A very interesting experiment on liver regeneration is here. Even if two-thirds of the liver is removed, the remaining ...
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What is contiguous premise culling and dangerous contact culling?

I am reading this paper related to FMD (foot and mouth disease) epidemics which occurred in UK. It mentioned about terms like IP (infected premise culling), CP (contiguous premise) and DC (dangerous ...
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92 views

What's a mouth ulcer/canker sore “made of”, and why do they develop?

Mouth ulcers are red/white rings with a crater. They are sore and last for 7-10 days. What I want to know is what they are 'made of' - i.e., what is the ring filled with, and why is the centre crater ...
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67 views

Do distinctions between dry, tickly and chesty coughs have any medical basis?

Background At least in Britain you normally come across distinct kinds of cough medicine "chesty", "dry" and "tickly". Questions Are "chesty", "dry" and "tickly" coughs always due to ...
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Can leukopenia in a person with an otherwise normal immune system lead to non-infectious diseases in the long-term?

If a person has developed leukopenia as a side-effect of long-term use of anti-convulsant medications and his/her immune system appears normal otherwise (does not get infections any more often than a ...
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Case Study and speculations of Edward Mordake

I am very interested in the case of the man named Edward Mordake who lived in the 19th century. In particular, he had two faces. If you have not heard of this man, please, search this up as there are ...
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128 views

Can Leptospirosis be spread through human urine

I am wondering if Leptospirosis can be spread via the urine of an infected human individual. All of the sources I have been able to find on the web have stated that the disease is primarily spread ...
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100 views

Congenital blindness due to retinitis pigmentosa - does it exist?

Retinitis pigmentosa (RP) patients typically become blind after a period of years in which their eye sight slowly deteriorates due to photoreceptor degeneration. Generally RP patients develop ...
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Finding confidence level of miRNA disease associations

I'm an undergraduate computer engineering student, and I have a project about bioinformatics. In this manner, I need to find prediction( or association I'm not sure the correct terminology) confidence ...
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Do people that don't feel pain shiver in the cold?

There are a few diseases that cause an insensitivity to pain. This question asks about the relationship between the cold and pain, which got me thinking: Is shivering a response driven by the ...
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111 views

Why do people with Down syndrome get fewer cancers?

I'm coming across some conflicting information regarding the correlation between cancer incidents and trisomy 21. I read a report from nature that discusses how Downs are only a tenth as likely to ...
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42 views

Detailed mechanism of the cause of diabetes mellitus type 1?

I have read in some texts that diabetes mellitus type 1 is caused by degeneration of beta cells due to our body's own immune reaction.Is it true? Can you explain further how are such types of immune ...
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101 views

Why is the upper respiratory tract so vulnerable to infections?

Wikipedia has the following statement on its Upper respiratory tract infection page: In United States URIs are the most common infectious illness in the general population. What is it about ...
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Are there anyother method under research for curing rabies? [duplicate]

Why is rabies incurable after onset of symptoms? Although we administer HRIG (lyssa virus antibody) to the patient, why doesn't it work after onset of symptoms? And are there any other successful ...
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192 views

In cancer, why do cells duplicate themselves?

In regards to cancer why do cells replicate themselves? If it's a mutation, what kind of mutation would this be classified as?
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Is there a graph or ontology that maps diseases to its possible causes or causing diseases?

I am looking for a mapping, list, ontology or graph that shows the connection between a diseases and its (currently known) causes and/or risk factors. For example a well known risk factor for acute ...
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54 views

Why does an complete molar pregnancy not result in a clone?

Complete molar pregnancy is one where an ovum devoid of nucleus is fertilized by a sperm after which the haploid set of chromosomes double to form a diploid set. As far as my understanding extends if ...
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Are some virus loads introduced to human cell but never triggered?

Is there a term or any evidence of phage DNA integrating into chromosomes/ DNA but never being triggered? For example, could a virus that affected Neanderthals still infect human cells today but is ...
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What is overdiagnosis?

What is overdiagnosis ? I have searched this Wiki result but didn't understood at all. Can you please explain the first two line of Wikipedia : Overdiagnosis is the diagnosis of "disease" that ...
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725 views

Why cancer is not a communicable disease?

I have seen this question where the author is asking a question about infectivity of virus. I wish to know why cancer is not a communicable disease?
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Is fever a disease or not?

I have seen this question where the author is asking why people take drugs for fever. So my question is: Is fever is a disease or not?
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Dimensions of an ulcer

This is my understanding of the dimensions of ulcer. Please answer if it's correct. Any more information is very welcome. Edge represents the lateral wall of ulcer. Margin represents the borders in ...
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Are abrasions considered closed wounds?

A closed wound is one where skin is intact and underlying tissue is not exposed to the environment. Abrasion is an erosion of skin usually due to sheering force. In most cases the dermis is intact ...
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Swellings with Variegated consistency

I am interested in knowing the names of all swellings with variegated consistency. I have come across the following: Malignant swelling with partial necrosis Caseated tuberculous lymph nodes ...
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Why do skin and nail go blue in cyanosis?

I have learned that Cyanosis presents with blue skin and nails. What is the reason for the blue coloration of the skin and nails? Why wont the skin and nails turn another color in the visible spectrum ...
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Are there any viruses that are part of all land animals?

An article on I Fucking Love Science (linked to below) got me thinking, are there any viruses that have been so successful that they have spread to all land animals similar to Toxoplasmosis which has ...
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238 views

Why doesn't HDL cause diseases like LDL? [duplicate]

LDL particles pose a risk for cardiovascular disease when they invade the endothelium and become oxidized, since the oxidized forms are more easily retained by the proteoglycans. A complex set of ...
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237 views

Why does our voice change when we get affected by cold or cough?

Why does our voice change when we get affected by cold or cough? I observed the voice change thing in so many people including me.
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93 views

Potential to destroy viruses using prions? [closed]

Could a prion be used to sufficiently deform a viral protein in order to make the virus it is a part of incapable of reproducing? For example, take the common cold's VP1 protein and turn it into a ...
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1answer
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Action of Ebola Viruses

This video suggests that the first cell to be the victim of viral infection of ebola is the dendritic cell which acts as the leader of immune system cells.But I am unable to understand how the ...
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1answer
55 views

Would humans eventually evolve to fight off fatal diseases if we didn't treat/vaccinate for them? [duplicate]

I am definitely pro vaccination, and the question is a bit morbid because people would die, but assuming that we didn't treat or vaccinate people for fatal diseases such as Ebola or the black death, ...
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Hydrophobia Outside of Rabies?

RELATED: Why does rabies cause hydrophobia? Agony, Hydrophobia and viruses in the light of evolutionary principles Has hydrophobia been found outside of rabies? I have only seen it ...