A tag used for questions on the mechanisms responsible for the initiation, development, and treatment of pathological processes in humans and animals.

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How to gauge the clinical significance of specific cell type presence?

How does one decide whether the presence of certain cell types is clinically important or negligible? Would the presence of certain cells in conjunction with other symptoms be enough, or should it be ...
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Predictive Single Nucleotide Polymorphisms (SNPs) for Bipolar Disorder

Are there any validated SNPs that are either predictive of developing bipolar spectrum disorder or are associated with its pathophysiology?
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Recovering Coma patient with theoretical full knowledge of heart function

In coma, there is the medullary depression (stage of agony). Spontaneous respiration and circulation cease i.e. vasomotor center. There is no full circulatory and respiratory support. Assume you ...
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55 views

Can non-carbonated energy drinks boost alcohol intoxication?

I just read news article about banning caffeine in alcohol drinks and about that energy drinks increase the urge to drink alcohol. Energy drinks cause sugar intoxication - answer about it here ...
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50 views

What are the mechanisms of disabling extrinsic control of heart?

I started this thread by thinking this question but I developed it further below What is the mechanism maintaining refractory period of pacemakers? My conjecture is that the mechanism is the ...
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8 views

How to Stabilize Histamine Surges in Exercise of MD/DMII?

I am studying how to stabilize histamine surges/effects without antihistamines in exercise of Metabolic Syndrome (MD) and Diabetes Mellitus II (DMII). Generic/simplified case: Symptoms in exercise: ...
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56 views

Why do leukemia and lymphoma cause “night sweats”?

One of the symptoms of these blood cancers is sleep hyperhidrosis (aka night sweats). Also referred to as one of the B-symptoms, it may be used for prognosis. What is the the mechanism behind the ...
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33 views

Can light pollution cause cancer?

Impaired circadian rhythm is associated with cancer. Light pollution affects the circadian rhythm and the circadian rhythm affects the metabolism. But what is the (molecular) connection between ...
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26 views

To prevent dry cough through reflex arch in chronic rhinitis?

Assume that the patient have atrophic nasal membranes after long chronic rhinitis. He is having frequent dry coughs through reflex arch induced by exercise, allergies, and ... You normally heal ...