This tag refers to how the body interacts with drugs such as how the body absorbs, distributes, metabolises and excretes (these four aspects of pharmacokinetics are often abbreviated ADME) said drugs.

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Pharmacology Half Life Calculation

I'm really stuck on this question. I'm being asked to find the half life of a drug. The Vd is 50L/kg. The clearance is 0.1 L/hr/kg. The patient weighs 70 kg. Equation is: T1/2 (halflife) = 0.693 * ...
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What is the physiological difference between snorting/swallowing cocaine

I know that mucosa inside the nose absorbs cocaine molecules when snorting cocaine, but what difference is there compared to swallowing? Also more cocaine administration equals more cocaine molecules ...
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Why can't sodium butyrate be delivered orally in humans and other mammals?

I think I know why -- bioavailability problems but since I have no firm evidence to support this theory I thought I would ask the biology stackexchange community for their input. I'd like some firm ...