Tagged Questions
4
votes
1answer
98 views
What is the biological mechanism underlying caffeine intolerance? (CYP1A2 or other?)
As far as I can tell, caffeine metabolism occurs primarily via the CYP1A2 enzyme. I am curious as to whether mutations in the CYP1A2 gene are associated with caffeine intolerance. Some site that is ...
0
votes
1answer
29 views
Does the Enzyme Monoamine Oxidase, Isoenzyme A have an allosteric modulatory site?
Does the Enzyme Monoamine Oxidase, Isoenzyme A (MAO-A) have an allosteric modulatory site? I ask because I would like to know if it is possible, in theory at least, for a positive allosteric modulator ...
0
votes
0answers
17 views
Which Enzymes Degrade Dynorphins and what drugs are there available to inhibit said enzymes?
Which Enzymes Degrade Dynorphins and what drugs are there available to inhibit said enzymes?
4
votes
0answers
102 views
How do the pharmacodynamics of the NSAIDs differ and are there “resistant” COX phenotypes?
I know that the non-steroidal anti-inflammatory drugs (e.g., aspirin, ibuprofen, naproxen) affect the enzymes cyclooxygenase (types I and II).
Is there any difference in the degree to which these ...
